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J Nutr Sci Vitaminol (Tokyo) ; 63(5): 291-297, 2017.
Article in English | MEDLINE | ID: mdl-29225313

ABSTRACT

Coffee polyphenols (CPPs) derived from coffee beans have beneficial effects on blood pressure and vascular endothelial function. In addition, CPPs suppress ultraviolet light induced erythema. However, the effects of CPPs on dry skin and cutaneous vascular function have not been clarified. We investigated the effects of CPPs on dry skin and the recovery rate (RR) of skin temperature after a cold-stress test as a measure of vascular function in subjects with visible scaliness in a double-blind, placebo-controlled, randomized study. The subjects were divided into two groups, the CPP group and the Placebo group. In the CPP group, the subjects ingested a beverage containing 297.8 mg CPPs every day for 4 wk. The degree of skin dryness was assessed quantitatively using a Visioscan to evaluate skin scaliness and smoothness. A subjective evaluation using a visual analog scale (VAS) of skin smoothness was also used. As a result, the scaliness and smoothness of cheek skin was significantly improved after 4 wk in the CPP group compared to the Placebo group. The improvements of the VAS score on 'skin smoothness' and the RR were also observed in the CPP group but the difference was not statistically significant. However, when the CPP group was divided into subgroups of high RR and low RR, the improvement of the RR was significant in the low RR subgroup. In conclusion, our results suggest that CPPs improve skin scaliness and play a role in cutaneous blood flow regulation after cold stress.


Subject(s)
Coffea/chemistry , Cold Injury/diet therapy , Dermatitis, Exfoliative/prevention & control , Dietary Supplements , Plant Extracts/therapeutic use , Polyphenols/therapeutic use , Stress, Physiological , Adult , Cold Injury/physiopathology , Dermatitis, Exfoliative/etiology , Dermatitis, Exfoliative/physiopathology , Double-Blind Method , Female , Hand , Humans , Immersion , Japan , Patient Dropouts , Re-Epithelialization , Regional Blood Flow , Seeds/chemistry , Severity of Illness Index , Skin/blood supply , Skin Temperature , Surface Properties
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