Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 104
Filter
1.
BMC Public Health ; 24(1): 1610, 2024 Jun 17.
Article in English | MEDLINE | ID: mdl-38886680

ABSTRACT

BACKGROUND: Condyloma acuminata (CA) is a common, and recurrent sexually transmitted disease (STD) that greatly contributes to direct health care costs and has a substantial psychosocial impact. Human papillomavirus (HPV) vaccination (containing L1 protein for HPV types 6 and 11) effectively controls CA. OBJECTIVES: We investigated attitudes toward the HPV vaccine for CA and willingness to undergo vaccination among STD clinic attendees in China. METHODS: Attendees at STD clinics at two selected hospitals in Guangdong and Jiangsu Provinces from May to September 2017 were requested to complete a self-administered questionnaire for this cross-sectional study. RESULTS: The participants' median age was 28 years (IQR: 24.0-34.0), and the sex ratio was balanced; 63.5% were from Guangdong, 36.5% were from Jiangsu, and 44.5% had a history of CA. The vaccine acceptance rate was high among the participants (85.8%,235/274) to whom the HPV vaccine for CA was available, especially among those who had heard of CA (89.0%, AOR = 3.14, 95% CI: 1.29-7.63, p = 0.0114). 95 (34.7%) of 274 participants had a positive attitude toward the HPV vaccine for CA. STD clinic attendees who had heard of the connection between HPV and CA (AOR = 2.56, 95% CI: 1.31-5.00, p = 0.0060), had heard of the HPV vaccines or cervical cancer vaccines (AOR = 1.90, 95% CI: 1.02-3.54, p = 0.0444) and had ever proactively discussed CA or the vaccine with others (AOR = 1.95, 95% CI:1.00-3.79, p = 0.0488) had better attitudes toward the HPV vaccine for CA. Over half of the participants (52.5%) expected the price of the HPV vaccine for CA to be under $90. CONCLUSION: The acceptance of the HPV vaccine for CA was high among STD clinic attendees in China, and the participants' self-perceived knowledge of CA and HPV was associated with better attitudes toward the HPV vaccine for CA. Education to improve knowledge is vital for reducing vaccine hesitancy.


Subject(s)
Condylomata Acuminata , Papillomavirus Vaccines , Patient Acceptance of Health Care , Humans , Condylomata Acuminata/prevention & control , Condylomata Acuminata/psychology , China , Female , Papillomavirus Vaccines/administration & dosage , Male , Adult , Cross-Sectional Studies , Patient Acceptance of Health Care/psychology , Patient Acceptance of Health Care/statistics & numerical data , Young Adult , Sexually Transmitted Diseases/prevention & control , Health Knowledge, Attitudes, Practice , Surveys and Questionnaires , Papillomavirus Infections/prevention & control , Ambulatory Care Facilities
2.
Arch Dermatol Res ; 313(10): 815-827, 2021 Dec.
Article in English | MEDLINE | ID: mdl-33433720

ABSTRACT

BACKGROUND: Anogenital warts are a common human papillomavirus infection. They cause emotional distress, especially when they are in the anogenital region. Cryotherapy is a first-line treatment. Previous clinical trials and case series have reported variable results with retinoids (isotretinoin) as adjuvant therapy. OBJECTIVE: To determine the safety and efficacy of low-dose oral isotretinoin as adjuvant treatment of anogenital warts. METHODS: Forty-six patients with anogenital warts were randomly assigned to isotretinoin + cryotherapy (n = 23) or only cryotherapy (n = 23). Patients were allocated via an interactive web-based randomization system. Evaluators were blinded to treatments. Isotretinoin 20 mg/daily + cryotherapy or cryotherapy were prescribed for 6 weeks. Patients were followed for 4 months. Genotyping of lesions was performed before treatment started. Dermatology Life Quality Index (DLQI) and Columbia-Suicide Severity Rating Scale (C-SSRS) were measured at the beginning and end of therapy. All patients completed the study. RESULTS: Both Groups had 50% clearance at the end of treatment. Recurrence in the combined group was not significantly lower than in the cryotherapy group (P = 0.59). Improvement was observed in the DLQI of all patients in both groups (P = 0.001). No suicidal intention was detected with the C-SSRS. Two patients (one in each group) had liver function test abnormalities after treatment. CONCLUSION: Combined therapy showed a slight not significant efficacy for anogenital warts in Hispanic patients. Low-dose isotretinoin seems to be safe even when it is used with cryotherapy on anogenital warts. TRIAL REGISTRATION: On April 25, 2019 with registration number DE19-00004, CONBIOÉTICA-19-CEI-001-20160404. Prospectively registered.


Subject(s)
Condylomata Acuminata/therapy , Cryotherapy , Isotretinoin/administration & dosage , Administration, Oral , Adult , Combined Modality Therapy , Condylomata Acuminata/diagnosis , Condylomata Acuminata/psychology , Dose-Response Relationship, Drug , Female , Humans , Isotretinoin/adverse effects , Male , Middle Aged , Prospective Studies , Quality of Life , Recurrence , Severity of Illness Index , Treatment Outcome , Young Adult
3.
J Dermatol ; 47(5): 503-511, 2020 May.
Article in English | MEDLINE | ID: mdl-32189395

ABSTRACT

Genital warts are a common sexually transmitted disease caused by human papillomavirus (HPV) infections. The prevalence of dementia is 4-8% in those aged 65 years or older in Taiwanese community studies, with a high social and economic burden for patients, family caregivers, the community and society. Previous studies have shown that viral infections such as herpes simplex and herpes zoster were associated with dementia. This study aimed to investigate the association between dementia and HPV infections. A population-based cohort study using data from Taiwan's National Health Insurance Research Database was conducted. Fine and Grays's survival analysis was employed to estimate the hazard ratios (HR) and 95% confidence intervals (CI) for the association between genital warts and dementia. From all of the potential participants aged 50 years or more, a total of 16 116 patients were enrolled, including 4029 genital warts-infected patients, with 12 087 sex-, age- and indexed date-matched controls (1:3). The cumulative incidences of dementia were 10.72 per 103  person-years and 6.43 per 103  person-years in the genital warts and control group, respectively. There were 475 dementia cases from the genital warts cohort during the follow-up period of 15 years. The adjusted HR for dementia was 1.485 (95% CI, 1.321-1.668; P < 0.001) for genital warts patients after adjusting for all of the covariates. Our study indicates that genital warts infection may increase the risk of dementia.


Subject(s)
Condylomata Acuminata/epidemiology , Cost of Illness , Dementia/epidemiology , Genital Neoplasms, Female/epidemiology , Genital Neoplasms, Male/epidemiology , Aged , Case-Control Studies , Condylomata Acuminata/psychology , Condylomata Acuminata/virology , Dementia/diagnosis , Female , Genital Neoplasms, Female/psychology , Genital Neoplasms, Female/virology , Genital Neoplasms, Male/psychology , Genital Neoplasms, Male/virology , Humans , Incidence , Male , Middle Aged , Retrospective Studies , Risk Factors , Simplexvirus/isolation & purification , Taiwan/epidemiology
4.
Int J Colorectal Dis ; 35(6): 1103-1110, 2020 Jun.
Article in English | MEDLINE | ID: mdl-32215680

ABSTRACT

PURPOSE: HIV infection and concomitant HPV-associated anal lesions may significantly impact on patients' quality of life (QoL), as they are predicted to have negative effects on health, psyche, and sexuality. MATERIAL AND METHODS: Fifty-two HIV+ patients with HPV-associated anal lesions were enrolled in a survey approach after undergoing routine proctologic assessment and therapy for HPV-associated anal lesions if indicated over a time span of 11 years (11/2004-11/2015). Therapy consisted of surgical ablation and topic treatment. QoL was analyzed using the SF-36 and the CECA questionnaires. RESULTS: Fifty-two of 67 patients (77.6%) were successfully contacted and 29/52 provided full information. The mean age was 43.8 ± 12.8 years. The median follow-up from treatment to answering of the questionnaire was 34 months. Twenty-one percent (6/29) of the patients reported suffering from recurrence of condyloma acuminata, three patients from anal dysplasia (10.3%). In the SF-36, HIV+ patients did not rate their QoL as significantly different over all items after successful treatment of HPV-associated anal lesions. In the CECA questionnaire, patients with persisting HPV-associated anal lesions reported significantly higher emotional stress levels and disturbance of everyday life compared to patients who had successful treatment (71.9/100 ± 18.7 vs. 40.00/100 ± 27.4, p = 0.004). Importantly, the sexuality of patients with anal lesions was significantly impaired (59.8/100 ± 30.8 vs. 27.5/100 ± 12.2, p = 0.032). CONCLUSION: HPV-associated anal lesions impact significantly negative on QoL in HIV+ patients. Successful treatment of HPV-associated anal lesions in HIV+ patients improved QoL. Specific questionnaires, such as CECA, seem to be more adequate than the SF-36 in this setting.


Subject(s)
Anus Neoplasms/complications , Carcinoma in Situ/complications , Condylomata Acuminata/complications , HIV Seropositivity/complications , Neoplasm Recurrence, Local , Quality of Life , Adolescent , Adult , Anus Neoplasms/pathology , Anus Neoplasms/psychology , Anus Neoplasms/therapy , Carcinoma in Situ/pathology , Carcinoma in Situ/psychology , Carcinoma in Situ/therapy , Condylomata Acuminata/psychology , Condylomata Acuminata/therapy , Follow-Up Studies , Humans , Male , Middle Aged , Recurrence , Sexual Behavior , Stress, Psychological/etiology , Surveys and Questionnaires , Time Factors , Young Adult
5.
Curr Med Res Opin ; 36(4): 705-712, 2020 04.
Article in English | MEDLINE | ID: mdl-32049551

ABSTRACT

Objective: To examine the construct validity and reliability of the Spanish version of the HPV Impact Profile scale (HIP) among women in Medellin, Colombia.Methods: We conducted a nested analysis of data from the pragmatic randomized controlled trial "Evaluation of Strategies for Optimal Clinical Management of Women with Atypical Squamous Cells of Undetermined Significance" (ASCUS-COL; NCT02067468). Women with Atypical Squamous Cells of Undetermined Significance (ASCUS) were randomly assigned to one of three triage strategies (Pap smear, colposcopy, HPV). Participants completed a questionnaire with sociodemographic information and the HIP scale translated into Spanish at baseline, two weeks after receiving triage test results, and one year after the second questionnaire. We conducted exploratory and confirmatory factorial analysis, and then assessed test reliability using Cronbach's alpha. Subsequently, we conducted multigroup confirmatory factor analysis to assess differences according to women´s age, and configurational invariance of the factor structure over the three time measures.Results: The sample consisted of 675 women, with a mean age of 40 years. The exploratory and confirmatory factor analysis for the HIP showed a seven-factor structure with appropriate adjustment indicators ([Formula: see text]= 1466.783, p < .0001). Only two items (1 and 10) had low factor loads and were removed from the confirmatory analysis. Multigroup analysis according to women's age showed acceptable goodness of fit (RMSEA = 0.037, CFI/TLI:0.998/0.998). The factor structure was similar among the tree measures and the model preserved acceptable goodness of fit (RMSEA = 0.079, CFI:0.86). The Cronbach's alpha for the total score was 0.91, with the lowest score for sexual impact (0.49) and the highest score for worries and concerns (0.90).Conclusions: The Spanish version of the HIP had adequate reliability and construct validity, and its use could be considered in clinic and research settings.


Subject(s)
Atypical Squamous Cells of the Cervix , Papillomavirus Infections/psychology , Triage/methods , Adult , Colposcopy , Condylomata Acuminata/psychology , Female , Humans , Middle Aged , Papanicolaou Test , Psychometrics , Reproducibility of Results , Uterine Cervical Dysplasia/psychology
6.
Actas Dermosifiliogr (Engl Ed) ; 110(7): 521-525, 2019 Sep.
Article in English, Spanish | MEDLINE | ID: mdl-30981378

ABSTRACT

Anogenital wart (AGW) resulting from human papilloma virus (HPV) is one of the most common sexually transmitted diseases worldwide. Herein, we aimed to evaluate the effects of AGW on patients'marital satisfaction and sexual function. This cross-sectional study was consisted of 74 consecutive patients including 37 patients with AGW and 37 healthy controls. ENRICH Marital Satisfaction Scale and Arizona Sexual Experience Scale were completed and analyzed for all patients. ENRICH scale items were not significantly different between the two groups. Sexual function was found to be lower in female than male patients (P<.001). According to our findings marital satisfaction was not affected by AGW. However, a history of previous treatment for HPV decreased the marital satisfaction. In addition, AGW had more adverse effects on females' sexual function compared to males. Our findings suggest that the psychiatric treatments should be considered when managing an AGW patient.


Subject(s)
Condylomata Acuminata/psychology , Personal Satisfaction , Sexual Behavior/psychology , Spouses/psychology , Adult , Case-Control Studies , Condylomata Acuminata/therapy , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Papillomaviridae , Psychotherapy , Sex Factors , Sexual Behavior/statistics & numerical data , Young Adult
7.
Int J STD AIDS ; 30(3): 264-274, 2019 03.
Article in English | MEDLINE | ID: mdl-30396319

ABSTRACT

Genital warts (GW) are mucosal or skin lesions caused by sexual transmission of human papillomavirus (HPV). This study estimates the frequency of GW cases in physicians' clinics and physicians' usual practices of GW referral and diagnosis in Peru. Participants in this study were a convenience sample of 100 physicians in five specialties: primary care (17), gynecology (37), urology (10), dermatology (31), and infectious diseases (5). Physicians completed a survey and daily log of all patients aged 18-60 years seen over ten days in their offices located in Peru. The survey recorded GW referral patterns and the daily log recorded patient demographic information and GW diagnosis. Among 12,058 patients, the annual GW prevalence (95% confidence interval [CI]) was 2.28% (2.02-2.56) and cumulative incidence (95% CI) was 1.60% (1.38-1.84). Physicians reported that most GW patients were direct consult (73.5% of male and 67.9% of females) and physicians treated most GW patients themselves (73.4% of males and 76.7% of females). As reported, the most common reasons for referring were 'serious cases requiring more specialized treatment' (73.2% of male and 72.2% of female) and 'lack of resources to treat' (26.8% of male and 27.8% of female). We conclude that GW cases are commonly seen by physicians in Peru.


Subject(s)
Condylomata Acuminata/epidemiology , Condylomata Acuminata/psychology , Health Resources/statistics & numerical data , Primary Health Care/statistics & numerical data , Quality of Life/psychology , Referral and Consultation/statistics & numerical data , Adolescent , Adult , Cross-Sectional Studies , Female , Humans , Incidence , Male , Middle Aged , Peru/epidemiology , Practice Patterns, Physicians' , Prevalence , Young Adult
8.
Viral Immunol ; 31(5): 346-351, 2018 06.
Article in English | MEDLINE | ID: mdl-29717924

ABSTRACT

The prevalence of genital warts (GW) and self-reported human papillomavirus (HPV) as well as disease-related psychosocial impact among male and female patients aged 18-60 years in India were assessed. GW prevalence was estimated using a 2-week daily log of patients examined from June 7-September 22, 2011 by 200 participating physicians in 6 regions of India. Psychosocial impact was estimated using one-time, self-administered surveys, including HPV Impact Profile (HIP), Cuestionario Específico para Condiloma Acuminado ([Spanish] CECA; "Specific questionnaire for Condylomata Acuminata") and EuroQol-5 Dimension survey. T-tests or Mann-Whitney U-tests were used for continuous comparisons and Chi-square or Fisher exact tests were applied for categorical comparisons. Overall GW prevalence in India was estimated at 1.07% (95% confidence interval = 0.97-1.17) and was higher among men than women. Regional prevalence ranged from high in Delhi (2.17%) to low in Bangalore (0.40%). Patients aged 25-29 years had the highest GW prevalence (1.42%). GW patients were most often newly diagnosed (74.07%). Among those with existing GW, 56.24% were recurrent, and 43.76% were resistant. According to total HIP scores, 55.4% of male GW patients and 20.0% of those without GW reported moderate psychological impact (p < 0.0001). HIP scores among women revealed that patients with abnormal Papanicolaou (Pap) test results (34.3%), precancerous lesions (46.2%), external GW (48.0%), and those without HPV-related disease (18.5%) reported moderate psychological impact (p = 0.0089) (Psychosocial impact results are reported in the Supplementary Data ). Estimated national GW prevalence, diagnosis, and treatment costs in India were higher for men than for women. GW in men and HPV infection in women had a negative psychosocial impact on well-being and health-related quality of life (HRQoL) scores, especially among women diagnosed with GW and precancerous lesions compared to those with other selected HPV-related diseases. Despite its limitations, this study provides an estimation of GW data in India not previously available.


Subject(s)
Condylomata Acuminata/epidemiology , Condylomata Acuminata/psychology , Quality of Life/psychology , Adolescent , Adult , Cross-Sectional Studies , Female , Humans , India/epidemiology , Male , Middle Aged , Prevalence , Surveys and Questionnaires , Young Adult
9.
Medicine (Baltimore) ; 97(9): e9917, 2018 Mar.
Article in English | MEDLINE | ID: mdl-29489693

ABSTRACT

Condyloma acuminata (CA) is a sexually transmitted disease that affects quality of life (QOL). CECA10 is an English-language questionnaire for assessing QOL in patients with CA, but there is no equivalent in China. This study aimed to develop a validated and reliable Chinese version of CECA10.The Chinese CECA10 was developed from the English version by forward translation, back translation, comparison with the original, cultural adjustments, and a pre-test (5 patients). The Chinese CECA10 and EuroQol Five Dimensions Three Level Questionnaire (EQ-5D-3L) was administered to patients with CA. Content validity (item/scale content validity indexes, I-CVI/S-CVI), test-retest reliability (intraclass coefficient, ICC), internal consistency (Cronbach α), criterion validity (comparison with the Dermatology Life Quality Index, DLQL, using Spearman correlation analysis), construct validity (exploratory factor analysis), and discriminant validity (between subgroups based on number of warts, number of recurrences, or number of sites involved) were assessed.The Chinese CECA10 had good test-retest reliability (ICC = 0.98, P < .001), internal consistency (Cronbach α values of 0.88, 0.84, and 0.83 for the total questionnaire, psychological dimension, and sexual dimension, respectively), content validity (I-CVI = 1 for all items), and criterion validity (r = -0.50, P < .001). Exploratory factor analysis extracted 2 factors with a cumulative contribution of 61.75%; the factor loading with each item was >0.4. Discriminant validity was not high. The mean CECA10 and EQ-VAS scores of 211 patients with CA (28.19 ±â€Š7.16 years; 139 males) were 34.56 ±â€Š19.01 and 64.64 ±â€Š19.28, respectively.The Chinese CECA10 has good reliability and validity for evaluating the QOL of Chinese patients with CA.


Subject(s)
Asian People/psychology , Condylomata Acuminata/psychology , Quality of Life , Surveys and Questionnaires/standards , Adolescent , Adult , China , Cross-Sectional Studies , Factor Analysis, Statistical , Female , Humans , Language , Male , Middle Aged , Reproducibility of Results , Translations , Young Adult
10.
Salud Publica Mex ; 60(6): 624-632, 2018.
Article in English | MEDLINE | ID: mdl-30699267

ABSTRACT

OBJECTIVE: To estimate the burden of genital warts (GW)in Mexico. MATERIALS AND METHODS: We estimated the annual incidence of GW based on data reported by specialist physicians. We also assessed GW treatment practices, the average cost of treatment, and the psychosocial burden of GW among patients. RESULTS: The annual incidence of GW in Mexico was estimated to be 547 200 cases. Treatment procedures vary by specialist and patient gender. The estimated annual cost was $195 million USD. The psychosocial impact of GW was slightly greater in males than females. CONCLUSIONS: This is the first evaluation of the burden of GW in Mexico. Our data suggest that GW are common, with significant health-related costs and psychosocial impact.


OBJETIVO: Estimar la carga por verrugas genitales (VG) en México. MATERIAL Y MÉTODOS: Estimamos la incidencia anual de VG, con base en información proporcionada por médicos especialistas y el manejo de las VG, así como el costo promedio del tratamiento y la carga psicosocial de las VG. RESULTADOS: La incidencia anual de VG en México fue de 547 200 casos. Los tratamientos variaron según la especialidad y el sexo del paciente. El costo anual por VG fue de $195 millones de dólares estadounidenses. El impacto psicosocial de las VG es ligeramente mayor en hombres que en mujeres. CONCLUSIONES: Esta es la primera evaluación de la carga de VG en México. Los datos sugieren que las VG son frecuentes, tienen costos relacionados con salud e impactos psicosociales significativos.


Subject(s)
Anus Diseases/epidemiology , Condylomata Acuminata/epidemiology , Genital Diseases, Female/epidemiology , Genital Diseases, Male/epidemiology , Adult , Anus Diseases/economics , Anus Diseases/psychology , Anus Diseases/therapy , Combined Modality Therapy , Condylomata Acuminata/economics , Condylomata Acuminata/psychology , Condylomata Acuminata/therapy , Cost of Illness , Female , Genital Diseases, Female/economics , Genital Diseases, Female/psychology , Genital Diseases, Female/therapy , Genital Diseases, Male/economics , Genital Diseases, Male/psychology , Genital Diseases, Male/therapy , Health Care Costs , Health Surveys , Humans , Incidence , Male , Medicine/statistics & numerical data , Mexico/epidemiology , Middle Aged , Papillomaviridae/isolation & purification , Papillomavirus Vaccines , Prevalence , Quality of Life
11.
An Bras Dermatol ; 92(3): 427-429, 2017.
Article in English | MEDLINE | ID: mdl-29186268

ABSTRACT

Anogenital warts are a worldwide public health problem. They consist of epithelial proliferations caused by HPV, whose transmission occurs mainly through sexual intercourse. In this study, we evaluated their impact on the quality of life of adult males. We interviewed 88 men in an outpatient clinic for sexually transmitted diseases at a Brazilian public institution, using the DLQI-BRA questionnaire. Most patients (81%) presented mild or no impairment of quality of life. The main dimensions affected were sex life, symptoms, and embarrassment. The low impact on quality of life may well justify the delay in seeking medical treatment, favoring the spread of the disease.


Subject(s)
Anus Diseases/psychology , Condylomata Acuminata/psychology , Quality of Life/psychology , Adult , Ambulatory Care Facilities , Humans , Male , Socioeconomic Factors , Surveys and Questionnaires
12.
An. bras. dermatol ; 92(3): 427-429, May-June 2017. tab, graf
Article in English | LILACS | ID: biblio-1038251

ABSTRACT

Abstract Anogenital warts are a worldwide public health problem. They consist of epithelial proliferations caused by HPV, whose transmission occurs mainly through sexual intercourse. In this study, we evaluated their impact on the quality of life of adult males. We interviewed 88 men in an outpatient clinic for sexually transmitted diseases at a Brazilian public institution, using the DLQI-BRA questionnaire. Most patients (81%) presented mild or no impairment of quality of life. The main dimensions affected were sex life, symptoms, and embarrassment. The low impact on quality of life may well justify the delay in seeking medical treatment, favoring the spread of the disease.


Subject(s)
Humans , Male , Adult , Anus Diseases/psychology , Quality of Life/psychology , Condylomata Acuminata/psychology , Socioeconomic Factors , Surveys and Questionnaires , Ambulatory Care Facilities
13.
J Pediatr Adolesc Gynecol ; 30(1): 96-101, 2017 Feb.
Article in English | MEDLINE | ID: mdl-27498340

ABSTRACT

STUDY OBJECTIVE: Cervical cancer morbidity and mortality are pressing public health issues that affect women in Haiti. To inform efforts to develop a human papillomavirus (HPV) vaccination program in Haiti, we sought to understand HPV awareness and willingness to get HPV vaccination in Haiti. DESIGN, SETTING, AND PARTICIPANTS: We interviewed a convenience sample of 475 women and men in 2 clinical settings in Port-au-Prince and Léogâne, Haiti between April and July 2014. INTERVENTIONS AND MAIN OUTCOME MEASURES: HPV awareness and willingness to get HPV vaccine for daughters. RESULTS: Few participants (27%, 130/475) had heard of HPV. Awareness of HPV was higher among respondents with a previous sexually transmitted infection compared with those without a previous sexually transmitted infection (odds ratio, 2.38; 95% confidence interval, 1.10-5.13). Adults who had heard of genital warts were also more likely to be aware of HPV compared with those who had not (odds ratio, 4.37; 95% confidence interval, 2.59-7.38). Only 10% (24/250) of parents had previously heard of HPV vaccine; however, after researchers explained the purpose of the vaccine, nearly all (96%, 240/250) said they would be willing to get HPV vaccine for their daughters if it were available. CONCLUSION: Despite low awareness of HPV in Haiti, interest in HPV vaccination was nearly universal in our study of health care-seeking adults. This high acceptability suggests that HPV vaccination programs instituted in Haiti would be well received.


Subject(s)
Health Knowledge, Attitudes, Practice , Immunization Programs , Mass Vaccination/psychology , Papillomavirus Infections/psychology , Papillomavirus Vaccines , Parents/psychology , Adolescent , Adult , Condylomata Acuminata/prevention & control , Condylomata Acuminata/psychology , Female , Haiti , Humans , Male , Nuclear Family/psychology , Papillomaviridae , Papillomavirus Infections/prevention & control , Surveys and Questionnaires , Uterine Cervical Neoplasms/prevention & control , Uterine Cervical Neoplasms/psychology
14.
Health Qual Life Outcomes ; 14(1): 163, 2016 Nov 28.
Article in English | MEDLINE | ID: mdl-27894347

ABSTRACT

BACKGROUND: A cost-utility study of a human papilloma virus (HPV) vaccine requires that the utility weights for HPV-related health states (i.e., cervical intraepithelial neoplasia (CIN), cervical cancer, and condyloma) be evaluated. The aim of the present study was to determine the utility weights for HPV-related health states. METHODS: Hypothetical standardised health states related to HPV were developed based on patient education material and previous publications. To fully reflect disease progression from diagnosis to prognosis, each health state comprised four parts (diagnosis, symptoms, treatment, and progression and prognosis). Nine-hundred members from the Korean general population evaluated the HPV-related health states using a visual analogue scale (VAS) and a standard gamble (SG) approach, which were administered face-to-face via computer-assisted interview. The mean utility values were calculated for each HPV-related health state. RESULTS: According to the VAS, the highest utility (0.73) was HPV-positive status, followed by condyloma (0.66), and CIN grade I (0.61). The lowest utility (0.18) was cervical cancer requiring chemotherapy without surgery, followed by cervical cancer requiring chemoradiation therapy (0.42). SG revealed that the highest utility (0.83) was HPV-positive status, followed by condyloma (0.78), and CIN grade I (0.77). The lowest utility (0.43) was cervical cancer requiring chemotherapy without surgery, followed by cervical cancer requiring chemoradiation therapy (0.60). CONCLUSIONS: This study was based on a large sample derived from the general Korean population; therefore, the calculated utility weights might be useful for evaluating the economic benefit of cancer screening and HPV vaccination programs.


Subject(s)
Condylomata Acuminata/psychology , Cost of Illness , Papillomavirus Infections/psychology , Patient Acceptance of Health Care/psychology , Quality of Life , Uterine Cervical Dysplasia/psychology , Uterine Cervical Neoplasms/psychology , Adult , Aged , Aged, 80 and over , Condylomata Acuminata/diagnosis , Condylomata Acuminata/therapy , Early Detection of Cancer , Female , Humans , Male , Middle Aged , Papillomavirus Infections/diagnosis , Papillomavirus Infections/therapy , Prognosis , Republic of Korea , Severity of Illness Index , Uterine Cervical Neoplasms/diagnosis , Uterine Cervical Neoplasms/therapy , Visual Analog Scale , Uterine Cervical Dysplasia/diagnosis , Uterine Cervical Dysplasia/therapy
15.
Health Commun ; 31(2): 139-49, 2016.
Article in English | MEDLINE | ID: mdl-26098812

ABSTRACT

Guided by the risk perception attitude framework (RPA), this study examined men's perceptions of risk and efficacy beliefs as predictors of their intentions to engage in self-protective behaviors. The results of multiple regression analyses did not provide support for the RPA prediction that efficacy beliefs moderate the relationship between risk perceptions and self-protective behavior. However, the results provide support for the main effects of risk and efficacy on all four behavioral intentions examined (i.e., Internet information seeking, communication with a health provider, HPV vaccination, and condom use). Risk and efficacy were positively related to (and significant individual predictors of) all four behavioral intentions. Scholarly and practical implications of these findings are discussed.


Subject(s)
Condylomata Acuminata/psychology , Health Knowledge, Attitudes, Practice , Papillomavirus Infections/psychology , Adolescent , Adult , Condoms/statistics & numerical data , Condylomata Acuminata/prevention & control , Health Behavior , Health Surveys , Humans , Information Seeking Behavior , Male , Papillomavirus Infections/prevention & control , Papillomavirus Vaccines/therapeutic use , Perception , Regression Analysis , Risk , Safe Sex , Self Efficacy , Young Adult
17.
BMC Public Health ; 14: 739, 2014 Jul 21.
Article in English | MEDLINE | ID: mdl-25048000

ABSTRACT

BACKGROUND: Genital warts (GW) are the most common sexually transmitted infections. To date, few studies using a human papillomavirus (HPV)-specific questionnaire have focused on the impact of quality of life (QoL) among patients with GW in developing countries. The origins of GW related psychosocial burdens and variations between genders were poorly characterized as well. METHODS: A hospital-based survey was conducted in Beijing and Nanjing of China in 2008. Eligible patients aged 18-65 who had a diagnosis of GW within 3 months were recruited. Demographic information, HPV knowledge, and assessment of psychosocial burden were collected by the HPV Impact Profile (HIP). The HIP examined 7 specific psychosocial domains by 29 items: (1) worries and concerns, (2) emotional impact, (3) sexual impact, (4) self-image, (5) partner and transmission, (6) interactions with physicians, and (7) control/life impact. HIP scores are reversely relates to the subjects' QoL, by which a higher score indicating a heavier psychosocial burden. RESULTS: Patients with GW experienced heavier psychosocial burdens than those of the general population, and females experienced heavier burdens than males (male vs. female: 49.20 vs.51.38, P < 0.001). "Self Image" and "Sexual Impact" were the two domains that affected patients the most, with mean HIP scores of 63.09 and 61.64, respectively. Women suffered heavier psychosocial burdens than men in the domain of "Worries and Concerns" (female vs. male: 54.57 vs. 42.62, P < 0.001), but lower psychosocial burdens in the domains of "Sexual Impact" (female vs. male: 59.16 vs. 65.26, P < 0.001) and "Interactions with Doctors" (female vs. male: 34.40 vs. 41.97, P < 0.001). Patients from Nanjing suffered a higher psychosocial burden than those of Beijing, especially in domains of "Emotional Impact", "Sexual Impact", "Partner and Transmission", and "Interactions with Doctors". CONCLUSIONS: Patients with GW suffered heavy psychological burden, and self-image and sexual-related concern were the primary cause of burdens. It's important to change the current biomedical model to bio-psycho-social model, and establish psychosocial support systems. The distinctions of origins of psychosocial burden between genders identified will be informative for prevention of GW and control efforts in China and other similar settings.


Subject(s)
Attitude to Health , Condylomata Acuminata/psychology , Papillomaviridae , Quality of Life/psychology , Stress, Psychological/psychology , Adolescent , Adult , China/epidemiology , Comorbidity , Condylomata Acuminata/epidemiology , Cost of Illness , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Self Concept , Sex Factors , Stress, Psychological/epidemiology , Surveys and Questionnaires , Young Adult
18.
Sex Transm Infect ; 90(7): 515-23, 2014 Nov.
Article in English | MEDLINE | ID: mdl-24787367

ABSTRACT

BACKGROUND: Targeted human papillomavirus (HPV) vaccine could prevent HPV-related cancers and genital warts among men who have sex with men (MSM). In order to develop effective vaccination programmes for MSM, it is crucial to understand their knowledge, beliefs about HPV and attitudes towards HPV vaccine. METHODS: A systematic search of 10 databases examined articles investigating HPV knowledge and HPV-related perceptions among MSM. Each paper was assessed to identify potential research directions in the context of targeted HPV vaccination for MSM. RESULTS: We identified 16 studies that included 5185 MSM and conducted mainly in North America. Generally, participants were over 26 years old, had poor-to-moderate knowledge about HPV and were not concerned about HPV-related diseases. Over a half of MSM were willing to accept HPV vaccine, if offered. However, there was large variability in HPV vaccine acceptability, partially due to inconsistencies in methods of ascertainment but also different levels of HPV vaccine awareness. CONCLUSIONS: Despite several misconceptions and poor knowledge of HPV infection, MSM might be receptive to HPV vaccination. However, further research is needed to identify which factors contribute to potential vaccine uptake in hypothetical MSM-targeted HPV vaccination. Future studies need to target those MSM with little sexual experience, who would benefit most from HPV vaccination.


Subject(s)
Anus Neoplasms/psychology , Bisexuality , Condylomata Acuminata/psychology , Health Knowledge, Attitudes, Practice , Homosexuality, Male , Papillomaviridae , Papillomavirus Infections/psychology , Papillomavirus Vaccines , Vaccination/psychology , Anus Neoplasms/prevention & control , Attitude to Health , Condylomata Acuminata/prevention & control , Humans , Male , Motivation , Papillomavirus Infections/prevention & control , Patient Acceptance of Health Care
19.
Rom J Morphol Embryol ; 55(1): 189-95, 2014.
Article in English | MEDLINE | ID: mdl-24715187

ABSTRACT

UNLABELLED: A 63-year-old patient, with no psychiatric history, was admitted in the psychiatric department with depressed mood, loss of interest in activities, apathy, insomnia, attention deficit, irritability, social withdrawal, prejudice and abandon delusions. Cerebral computed tomography (CT) scan was normal but the general physical examination revealed a voluminous tumor in the inguino-pubic-ano-genital area measuring 350/80/40 mm, which appeared 15 years ago and grew gradually leading to local rickety hygiene and also to depression, especially in the last time period when the tumor grew faster. The DSM-IV-TR diagnostic was affective disorder due to general medical condition. Surgical exams concluded it was a giant exophytic tumor and was recommended a pre-operative abdominal CT scan, which did not revealed metastatic spread. The treatment consisted in wide radical excision into the tumor-free resection margins. Anatomopathological exam concluded condyloma acuminatum - Buschke-Löwenstein tumor (BLT), a very rare borderline tumor. In post-operative period, progress of depression was spectacular, with the full mental recovery by decreasing the antidepressant and antipsychotic medication, fact that strengthen the initial diagnostic of depression due to a general medical condition. CONCLUSIONS: Patients diagnosed with BLT may develop mental disorders especially with devaluation and low self-esteem, social withdrawal and secondary functional impairment. Due to the malignancy risk in such tumors and also the psychiatric unfavorable recovery prognostic in case of continuous general medical condition, the only effective treatment is tumor resection with surgical, oncological, psychiatric postoperative revaluation.


Subject(s)
Buschke-Lowenstein Tumor/psychology , Condylomata Acuminata/psychology , Depression/psychology , Psychotic Disorders/psychology , Buschke-Lowenstein Tumor/pathology , Buschke-Lowenstein Tumor/surgery , Condylomata Acuminata/pathology , Condylomata Acuminata/surgery , Epidermis/pathology , Humans , Hyperplasia , Keratinocytes/pathology , Male , Middle Aged , Preoperative Care
20.
Int J STD AIDS ; 25(13): 949-55, 2014 Nov.
Article in English | MEDLINE | ID: mdl-24671715

ABSTRACT

To assess gender-specific impact of genital warts on health-related quality of life (HRQoL), and to explore to what extent sexual characteristics and clinical symptoms influenced the impact on emotional and sexual well-being of both sexes. We conducted a survey of sexual and clinical characteristics from persons diagnosed with genital warts at STI clinics. HRQoL was measured using two measurement tools: 1) the generic EQ-5D; and 2) the genital warts-specific CECA-10 including an emotional well-being and a sexual activity dimension. The EQ-5D scores were compared with scores of the general population. Descriptive analyses were used to explore characteristics associated with HRQoL scores stratified for gender. The HRQoL-measurement tools showed that genital warts have especially an emotional impact. The impact of genital warts on HRQoL was greater for women than for men. In addition, the CECA-10 showed that in women the impact of genital warts on sexual activity was influenced by age, relationship status and number of warts. No related factors were seen in men. Genital warts have a greater impact on women than on men. In women, sexual and clinical factors influenced the impact of genital warts on well-being, whereas in men no such factors were found.


Subject(s)
Condylomata Acuminata/psychology , Emotions , Quality of Life , Sexual Behavior , Sexual Partners , Adult , Aged , Analysis of Variance , Case-Control Studies , Condylomata Acuminata/diagnosis , Condylomata Acuminata/epidemiology , Female , Health Status , Health Surveys , Humans , Male , Middle Aged , Quality of Life/psychology , Reproductive Health , Sex Distribution , Socioeconomic Factors , Surveys and Questionnaires
SELECTION OF CITATIONS
SEARCH DETAIL
...