Subject(s)
Humans , Male , Adult , Middle Aged , Darier Disease/diagnosis , Darier Disease/etiology , Darier Disease/pathology , Darier Disease/therapy , Granuloma Annulare/diagnosis , Granuloma Annulare/pathology , Granuloma Annulare/therapy , Darier Disease/classification , Darier Disease/complications , Darier Disease/prevention & control , Granuloma Annulare/classification , Granuloma Annulare/complications , Granuloma Annulare/prevention & controlABSTRACT
Darier disease is an autosomal-dominant inherited genodermatosis. A woman is described who had Darier disease and hereditary spherocytosis whose inframammary Darier disease had dramatic and sustained improvement following reduction mammaplasty. The postoperative resolution of the dermatosis beneath the patient's breasts introduces the possibility that, when appropriately indicated, breast reduction surgery may have a potential role in the management of severe inframammary Darier disease.
Subject(s)
Darier Disease/prevention & control , Mammaplasty , Chronic Disease , Darier Disease/diagnosis , Female , Humans , Middle Aged , Neck Pain/etiology , Postoperative Complications , Shoulder Pain/etiologyABSTRACT
A hypothesis according to which two types of keratosis follicularis (below) should be differentiated is discussed with reference to clinical findings recorded during mass screening in kindergartens and in a dermatological practice: (1) condition improves, to normal in early adulthood, a type in which the for which heritability not cannot be identified by mass screening; (2) a type with growing incidence, primarily among women up to 30 years of age, caused by an X-linked dominant gene.