Treatment Update of Port-Wine Stain: A Narrative Review.

BACKGROUND: Port-wine stain (PWS) is a congenital vascular malformation affecting 0.3–0.5% of normal population. These characteristic lesions arise due to the interplay of vascular, neural, and genetic factors. Treatment options include lasers, cosmetic tattooing, electrotherapy, cryosurgery, derma-abrasion, and skin grafting; however, none of these treatment alternatives appears to be satisfactory and is unable to provide consistent, satisfactory responses or even complete cures. Currently, laser is the treatment of choice, as it is comparatively safe and more effective than other procedures. The most commonly used modality is pulsed dye laser (PDL). The literature research includes peer-reviewed articles (clinical trials or scientific reviews). Studies were identified by searching electronic databases (MEDLINE and PubMed) to January 2020 and reference lists of respective articles. Only articles published in English language were included. J Drugs Dermatol. 20(5): doi:10.36849/JDD.5005.

[Advances in the research of dermabrasion in burn wounds].

The process of burn wounds healing includes the removal of necrotic tissue, the hyperplasia of granulation tissue and epithelialization. The removal of necrotic tissue is the first step in dealing with burn wounds. Although there are a variety of adjuvant drugs for removing necrotic tissue, surgical debridement is still the main way of debridement of burn wounds. Surgical debridement of burn wounds includes escharectomy, tangential excision and dermabrasion. Escharectomy and tangential excision have been widely used in clinical practice, while dermabrasion has not been known to the majority of burns colleagues. This article summarizes the clinical application and progress of dermabrasion in burn wounds.

Recent advances in physical delivery enhancement of topical drugs.

The skin has evolved to resist the penetration of foreign substances and particles. Effective topical drug delivery into and/or through the skin is hindered by these epidermal barriers. A range of physical enhancement methods has been developed to selectively overcome this barrier. This review discusses recent advances in physical drug delivery by broadly separating the techniques into two main areas; indirect and direct approaches. Indirect approaches consist of electrical, vibrational or laser instrumentation that creates pores in the skin followed by application of the drug. Direct approaches consist of mechanical disruption of the epidermis using techniques such as microdermabrasion, biolistic injectors and microneedles. Although, in general, physical techniques are yet to be established in a clinical setting, the potential gains of enhancing delivery of compounds through the skin is of great significance and will no doubt continue to receive much attention.

[Laser treatment of wrinkles. Update]. / Laser-Faltenbehandlung: Update.

Prolonged exposure to UV-radiation induces a variety of visible skin changes such as lentigines, actinic keratoses and solar elastosis. Laser skin resurfacing using ablative lasers (CO(2) or Erbium:YAG) is a popular procedure to reduce these marks and improve the aesthetic appearance of photoaged facial skin. Skin resurfacing is defined as an ablation of the upper layers of facial skin. Possible side effects are hyperpigmentation, hypopigmentation and, at worst, scarring. The"down time" after the skin resurfacing procedure is about 7 to 10 days. This is the major drawback of resurfacing and the main reason why subsurfacing/skin rejuvenation is becoming even more popular. The literature is not clear on whether this newer approach is as effective as resurfacing.

Treatment of acne scarring.

One of the most distressing side effects of acne vulgaris is the development of acne scars. In this article, the authors discuss the history of and current modalities in use for the treatment of acne scars. The discussion includes resurfacing, dermabrasion, laser surgery, peels, punch excisions, and the use of fillers.

Current trends in the practice of dermatologic surgery.

In a 1984 survey, 2750 members of the American Academy of Dermatology were asked which dermatologic surgery procedures they performed and which procedures they expected to be performing in 5 years. A similar survey was completed by the American Society for Dermatologic Surgery in 1988. In this article, the results of the 1988 survey are presented and compared to that of 1984.

Dermabrasion: state of the art.

Dermabrasion was developed to remove acne scars but has now been utilized for other cosmetic and therapeutic problems. New instruments, anesthesia, and postoperative dressings have given rise to improved results. Complications and contraindications are emphasized. There is an increased popularity in dermabrasion.