1.
J Pharm Sci
; 67(8): 1167-8, 1978 Aug.
Article
in English
| MEDLINE
| ID: mdl-671259
ABSTRACT
Starting from D-phenylalanine, dextroamphetamine sulfate and methamphetamine hydrochloride were synthesized. The reaction sequence proceeds through three intermediates, in which the absolute configuration of the asymmetric carbon atom is changed but the relative configuration remains the same. Either product can be obtained from a common intermediate by altering the reductive conditions employed for the removal of a carbamate protecting group.