1.
Mult Scler Relat Disord
; 21: 69-70, 2018 Apr.
Article
in English
| MEDLINE
| ID: mdl-29474980
ABSTRACT
Fingolimod, taken orally once per day, is approved for the treatment of relapsing-remitting multiple sclerosis (MS). It should be stopped at least two months before conception as it is not considered safe during pregnancy or when breast feeding. In vitro and animal studies have found a possibly increased risk of congenital abnormalities following exposure to Fingolimod. Here, we report a 34-year-old female, with a 10-year history of MS who had unexpected pregnancy with exposure to generic Fingolimod during the first 7 weeks. The infant was born with dextrocardia, but without any further structural cardiac or other abnormalities.
Subject(s)
Dextrocardia/chemically induced , Fingolimod Hydrochloride/adverse effects , Immunosuppressive Agents/adverse effects , Multiple Sclerosis, Relapsing-Remitting/drug therapy , Pregnancy Complications/drug therapy , Pregnancy Trimester, First , Dextrocardia/diagnostic imaging , Female , Fingolimod Hydrochloride/therapeutic use , Humans , Immunosuppressive Agents/therapeutic use , Pregnancy , Pregnancy, Unplanned
2.
J Med Genet
; 31(5): 423, 1994 May.
Article
in English
| MEDLINE
| ID: mdl-7914930
Subject(s)
Abnormalities, Drug-Induced/etiology , Abnormalities, Multiple/chemically induced , Dibenzazepines/adverse effects , Esophageal Atresia/chemically induced , Tracheoesophageal Fistula/chemically induced , Cryptorchidism/chemically induced , Dextrocardia/chemically induced , Female , Humans , Infant, Newborn , Lumbar Vertebrae/abnormalities , Male , Maternal-Fetal Exchange , Pregnancy , Syndrome
3.
Acta Paediatr
; 83(4): 411, 1994 Apr.
Article
in English
| MEDLINE
| ID: mdl-8025399
4.
Orv Hetil
; 124(48): 2935-6, 1983 Nov 27.
Article
in Hungarian
| MEDLINE
| ID: mdl-6657241
Subject(s)
Abnormalities, Multiple/chemically induced , Dextrocardia/chemically induced , Heart Defects, Congenital/chemically induced , Lung/abnormalities , Methylprednisolone/adverse effects , Female , Humans , Infant, Newborn , Maternal-Fetal Exchange , Pregnancy , Pregnancy Complications/drug therapy
5.
Teratology
; 1(1): 109-18, 1968 Feb.
Article
in English
| MEDLINE
| ID: mdl-5696813
Subject(s)
Abnormalities, Drug-Induced/etiology , Aorta/abnormalities , Fetal Heart/abnormalities , Salicylates/poisoning , Animals , Aspirin/administration & dosage , Dextrocardia/chemically induced , Female , Gestational Age , Maternal-Fetal Exchange , Pregnancy , Rats , Transposition of Great Vessels/chemically induced
6.
Anat Rec
; 156(2): 175-90, 1966 Oct.
Article
in English
| MEDLINE
| ID: mdl-5969672
