1.
Renal function, insulin secretion, and glucose tolerance in mild streptozotocin diabetes in the dog.
Am J Vet Res
; 39(5): 807-9, 1978 May.
Article
in English
| MEDLINE
| ID: mdl-153115
ABSTRACT
A mild, stable diabetes mellitus was induced in dogs, using a small (20 mg/kg of body weight) dose of streptozotocin in a standard volume of 200 ml infused in 15 minutes. The stability of the diabetes was evidenced by the results of a standard intravenous glucose-tolerance test, insulin response to the glucose load, and urinary glucose excretion. The results of the urinary clearances for urea, creatinine, and phosphate indicated minimal renal toxicosis and that the toxicosis was localized to the tubules.
Subject(s)
Blood Glucose/analysis , Diabetes Mellitus, Experimental/veterinary , Dog Diseases/chemically induced , Insulin/metabolism , Kidney/physiopathology , Animals , Diabetes Mellitus/metabolism , Dog Diseases/metabolism , Dogs , Female , Glucose Tolerance Test , Glycosuria/veterinary , Injections, Intravenous , Insulin Secretion , Male , Phosphates/urine , Streptozocin/administration & dosage , Urea/urine
2.
Am J Vet Res
; 31(9): 1577-87, 1970 Sep.
Article
in English
| MEDLINE
| ID: mdl-4918899
Subject(s)
Blood Chemical Analysis , Diabetes Mellitus, Experimental/veterinary , Fetal Diseases/veterinary , Pancreas/pathology , Pregnancy in Diabetics/veterinary , Sheep Diseases/metabolism , Animals , Blood Glucose/analysis , Diabetes Mellitus, Experimental/metabolism , Diabetes Mellitus, Experimental/pathology , Disease Models, Animal , Fatty Acids, Nonesterified/blood , Female , Fetal Diseases/metabolism , Fetal Diseases/pathology , Fructose/blood , Histological Techniques , Ketones/blood , Maternal-Fetal Exchange , Pregnancy , Sheep , Sheep Diseases/pathology
3.
Kyoto Daigaku Kokukagaku Kiyo
; 8(2): 97-110, 1968.
Article
in Japanese
| MEDLINE
| ID: mdl-5252869
4.
Zentralbl Veterinarmed A
; 13(5): 392-404, 1966 Jul.
Article
in German
| MEDLINE
| ID: mdl-4959052
