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Padiatr Padol ; 23(4): 343-8, 1988.
Article in German | MEDLINE | ID: mdl-2907379

ABSTRACT

A toxicological investigation of urine could finally explain abnormal neurological symptoms with apnea. 2 Cibalen-suppositories for children were given to an 7 week old infant as treatment of an upper respiratory infect. 12 hours were between the application of the 2 suppositories. 2 hours after the second application coma, hypertonus, opisthotonus, miosis and depression of ventilation were found. 10 hours later an apnea occurred. These symptoms were due to the synergistic effect of Phenobarbital, Aminophenazon and Codeinphosphat in an overhigh dose.


Subject(s)
Aminopyrine/poisoning , Barbiturates/poisoning , Codeine/poisoning , Diphenylacetic Acids/poisoning , Respiratory Insufficiency/chemically induced , Respiratory Tract Infections/drug therapy , Aminopyrine/administration & dosage , Aminopyrine/adverse effects , Barbiturates/administration & dosage , Barbiturates/adverse effects , Codeine/administration & dosage , Codeine/adverse effects , Diphenylacetic Acids/adverse effects , Drug Combinations/adverse effects , Drug Combinations/poisoning , Humans , Infant , Male , Suppositories
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