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J Chromatogr ; 156(1): 189-95, 1978 Aug 21.
Article in English | MEDLINE | ID: mdl-29024

ABSTRACT

A high-performance liquid chromatographic method for the determination of low levels (less than 1 microgram/ml) of the basic metabolite of bezitramide, 1-(4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one, in human urine is described. Special attention is given to the separation from the basic metabolite of droperidol, a drug frequently co-administered with bezitramide.


Subject(s)
Analgesics/urine , Benzimidazoles/urine , Piperidines/urine , Antipsychotic Agents/urine , Chromatography, High Pressure Liquid , Droperidol/urine , Humans , Hydrolysis , Methods , Pimozide/analogs & derivatives , Pimozide/urine , Solubility , Spectrophotometry, Ultraviolet
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