Giardia duodenalis and dysentery in Iron Age Jerusalem (7th-6th century BCE).

The aim of this study was to determine if the protozoa that cause dysentery might have been present in Jerusalem, the capital of the Kingdom of Judah, during the Iron Age. Sediments from 2 latrines pertaining to this time period were obtained, 1 dating from the 7th century BCE and another from the 7th to early 6th century BCE. Microscopic investigations have previously shown that the users were infected by whipworm (Trichuris trichiura), roundworm (Ascaris lumbricoides), Taenia sp. tapeworm and pinworm (Enterobius vermicularis). However, the protozoa that cause dysentery are fragile and do not survive well in ancient samples in a form recognizable using light microscopy. Enzyme-linked immunosorbent assay kits designed to detect the antigens of Entamoeba histolytica, Cryptosporidium sp. and Giardia duodenalis were used. Results for Entamoeba and Cryptosporidium were negative, while Giardia was positive for both latrine sediments when the analysis was repeated three times. This provides our first microbiological evidence for infective diarrhoeal illnesses that would have affected the populations of the ancient near east. When we integrate descriptions from 2nd and 1st millennium BCE Mesopotamian medical texts, it seems likely that outbreaks of dysentery due to giardiasis may have caused ill health throughout early towns across the region.

The dysentery epidemic in Poland in 1920-1921

This article describes in general the issues related to the dysentery epidemic in 1920-1921. The current literature on the subject lacks publications presenting these issues fully. Based on historical sources from that period, including articles published in medical magazines, the incidence rate, the methods and results of the battle against that epidemic were depicted. The article represents an important contribution to a better insight in the struggle of Polish medical services with infectious diseases afflicting people in the first years following the end of World War I. It also sheds light on the development of Polish studies on infectious diseases in the Second Polish Republic, the scientists' belief in the successful treatment of epidemic diseases and understanding of the need to educate people about the rules of hygiene and taking medicines.

Biological and Cultural Causes of Seasonality of Deaths in Historical Populations From Poland.

Seasonal fluctuations in mortality and their causes in the nineteenth century Polish rural populations: wealthy, agriculturally and economically advanced populations from Wielkopolska, and poor populations from Silesia and Galicia (southern Poland) were described. Data-sources included parish death registers from the Roman Catholic parish of Dziekanowice in the region of Wielkopolska, Prussian statistical yearbooks for the Pozna Province as well as information from previous publications regarding Silesia and Galicia. The 19th century patterns were compared with those in present-day Poland. The occurrence of seasonality of deaths was assessed with: the Chi-squared test, the Kolmogorov-Smirnov test, and the Autoregressive Integrated Moving Average Models (ARIMA). In all populations there was a winter maximum of the number of deaths, while the minimum occurred in early summer. In the poor populations of Silesia and Galicia another statistically significant increase in the incidence of deaths was observed in the early spring. In the rich and modern villages of Wielkopolska there was no spring increase in the number of deaths, however, in all populations of Wielkopolska, irrespective of a particular pattern, a secondary mortality peak occurred in the late summer and autumn. Statistical tests used in this study did not show any clear differences in the distribution of the seasonality of deaths between the populations of Wielkopolska on the one hand, and the populations from Galicia and Silesia, on the other hand. The statistical significance of differences was, however, evident between populations representing the two distinguished by secondary peaks death seasonality patterns. Seasonal death increase split the populations under study into two groups according to the criterion of wealth.

Cure for empire: the 'Conquer-Russia-Pill', pharmaceutical manufacturers, and the making of patriotic Japanese, 1904-45.

Seirogan, a popular anti-diarrhoeal pill, is arguably one of the most successful pharmaceutical products of modern Japan. What is less known is that the Japanese army initially developed Seirogan during the Russo-Japanese War as the 'Conquer-Russia-Pill', which was later marketed to the public by private manufacturers. Previous scholars have emphasised the top­down governmental method of mobilising private sectors to manipulate public opinion for the cause of external imperialist expansion and domestic stability during wartime Japan. But the matrix that the Conquer-Russia-Pill allows us to glimpse is an inverted power relation among the state, commercial sectors, and imperial citizens. While the Japanese government remained indifferent if not hostile to jingoistic pharmaceutical manufacturers who could easily disrupt international relations, pharmaceutical companies quickly recognised and exploited the opportunities that the Conquer-Russia-Pill and its symbolism provided under the banner of the empire. In turn, Japanese consumers reacted to commercial sermons carefully anchored in patriotic and militaristic discourses and images by opening their wallets. In other words, the popularity of the Conquer-Russia-Pill was a culmination of the convergence of a governmental initiative to enhance military capabilities, the commercial ingenuity of pharmaceutical manufacturers, and a consumer response to patriotic exhortations.

[The medical literature of the Egyptian campaign]. / La littérature médicale de la campagne d'Egypte.

Bonaparte's Egyptian Campaign (1798 - 1801), like all other episodes from the Napoleonic era, gave rise to an extensive literature on the subject, but most of all a significant medical literature. This fact is due to many reasons:--an important health service for this expeditionary corps of more than 36.000 men, with two main figures at its hea, Desgenettes and Larrey--but also with valuable subordinates like Assalini, Savaresi, Balme, Pugnet or Barbès.--A Commission for Science and Art, of which a few doctors and surgeons were members, but most of all pharmacists like Boudet or Rouyer--The presence in the field of Ludwig Frank, the nephew of the famous Johann Peter Frank.--The creation in Cairo of an Egyptian Institute and the publication of the masterly Description of Egypt and the establishment of printing houses.--The emergence of the myth of the Orient and its mysteries.--An extensive array of indigenous pathologies, which is characteristic of those countries. For instance: plague, dysentery, yellow fever, Egyptian ophthalmia, as well as more common diseases like tetanus, scurvy or venereal diseases. The main medical works that cover this period and its pathologies are skimmed.

[Citation errors: Uplavici (for Hlava) and William the Silent (for Jules Verne and Mignet)]. / Références erronées: Uplavici (pour Hlava) et Guillaume le Taciturne (pour Jules Verne et Mignet).

A certain 'O Uplavici' was cited for more than fifty years, although he had never existed. This error probably came from a misinterpretation of the Czech language, in which the real author's name--Hlava--can mean 'Title'. It was finally recognized, which was not the case for the author of the sentence: 'I have no need of hope to take action, nor of success to persevere', it is still regularly attributed in France to William I, Prince of Orange, called the Silent. It is a mistake, and no serious reference certifies that an historical figure would have pronounced this sentence. It was written by the historian Mignet in 1841, to describe the character of William III, Prince of Orange and King of England. It was then used in 1875 by Jules Verne, to describe a character in 'The Mysterious Island'.

INCAP studies of nutrition and infection.

As soon as the Institute of Nutrition of Central America and Panama (INCAP) began to study the poor nutritional status and stunting of children in the rural villages of Central America, it was apparent that infections, particularly diarrheas, were also a serious problem. Studies of kwashiorkor indicated that infections precipitated kwashiorkor and anemia in children who were already malnourished. In the 1940s there was almost no suggestion in the literature of a relation between nutrition and infection. INCAP gradually identified the mechanisms by which any infection worsens nutritional status and demonstrated that infections were more severe and more often fatal in malnourished children and adults. These studies ultimately led to the 1968 World Health Organization (WHO) monograph "Interactions of nutrition and infection" and widespread recognition by public health workers of the importance of this relationship for morbidity and mortality in poorly nourished populations.

Disentería y absceso hepático en el Chile colonial y republicano: el Doctor Miguel Claro Vásquez / Disentery and hepatic abscess in the colonial and republican Chile: Doctor Miguel Claro Vásquez

En esta comunicación se destaca la frecuencia y gravedad en Chile, durante la época colonial y republicana, de dos entidades clínicas: disentería y absceso hepático, comprobándose finalmente la etiología amebiana en ambos procesos. Además se distingue al doctor Miguel Claro Vásquez, médico, después sacerdote y obispo de la Iglesia Católica, por su aporte a la cirugía del absceso del hígado.

"War dysentery" and the limitations of German military hygiene during World War I.

This article examines major epidemics of bacillary dysentery in the German army as well as among civilians in eastern Europe and in Germany during World War I. These epidemics were all the more surprising in light of prewar advances in understanding the disease and limiting dysentery outbreaks. Three major reasons are adduced for the incapacity of German military hygienists to prevent wartime epidemics. First was the difficulty of bacteriological testing at the front, especially early in the war, with negative consequences for diagnosis, therapy, and disease control. Second was inadequate hygiene including major shortcomings in latrine cleanliness and attempts to grapple with the "fly plague." Third was the lack of a Pasteur-type vaccine until late in the war. Susceptibility to dysentery was also heightened by war-related nutritional deficiencies. Taking off from an article by the English medical historian Roger Cooter, this article shows that the concept of "war dysentery" was socially constructed and served a variety of professional interests but at the same time takes issue with Cooter's arguments against linking "war" and "epidemics" pathogenetically.

La Mettrie's soul: vertigo, fever, massacre, and The Natural History.

La Mettrie's materialist and monistic philosophy is that of a military doctor, knowing what dysentery did to his own mind, watching his regiment destroyed at Fontenoy, running French field hospitals in Flanders. He learned brain science in the injuries of his fellows. He knew pain and that man's main positive drive was sex. He despised the prudish hypocrisies of feeble materialists like Diderot and Voltaire. His brutal military life and his hedonism made him the most coherent monist against Cartesian dualism. His study of vertigo is sound clinical medicine, which well accords with one trend in today's medical practice.

"More fatal than powder and shot": dysentery in the U.S. Army during the Mexican War, 1846-48.

In terms of deaths due to disease, the Mexican War (1846-48) was the deadliest of all American wars. Nearly 13% of the entire U.S. force perished from disease. Of the total 12,535 war deaths, 10,986 (88%) were due to infectious diseases (overwhelmingly dysentery, both bacterial and amoebic); seven men died from disease for every man killed by Mexican musket balls. Camp pollution was the greatest error committed by U.S. troops in the Mexican War. The indifference of line officers and recruits to the need for proper sanitation and military hygiene fueled the dysentery outbreaks, and the poor conditions in military hospitals contributed further to the spread of disease. This defect in military culture undermined the health of the army and led to medical disaster. Disease caused an enormous drain on the U.S. Army's resources, eroded troop morale, and influenced strategy and tactics. As we enter the 21st century, dysentery is still a major public health threat, killing hundreds of thousands of people annually-primarily children in developing countries where personal hygiene is poor and disposal of human and animal wastes is indiscriminate.

Transforming public health?: a critical review of progress made against enteric diseases during the American-led occupation of Japan (1945-52).

Historical assessments of the Occupation's efforts to tackle enteric diseases (cholera, typhoid, paratyphoid and dysentery) have generally reflected a celebratory narrative of US-inspired public health reforms, strongly associated with the head of the Public Health and Welfare Section, Crawford F. Sams. Close inspection of the documentary record, however, reveals much greater continuity with pre-war Japanese public health practices than has hitherto been acknowledged. Indeed, there are strong grounds for disputing American claims of novelty and innovation in such areas as immunisation, particularly in relation to typhoid vaccine, and environmental sanitation, where disparaging comments about the careless use of night soil and a reluctance to control flies and other disease vectors reveal more about the politics of public health reform than the reality of pre-war practices. Likewise, the representation of American-inspired sanitary teams as clearly distinct from and far superior to traditional sanitary associations (eisei kumiai) was closer to propaganda than an accurate rendering of past and present developments.

[National Institute of Hygiene during the World War 1939-1944]. / Panstwowy Zaklad Higieny w czasie wojny w latach 1939-1944.

The article presents history of the National Institute of Hygiene (PZH) in the period from September 1939 until the fall of Warsaw Uprising (1944). German occupation left unaltered activities, structure and Polish personnel of the Institute, enforcing commissoner board by professor Ernst Nauck, and subsequently--professor Robert Kudicke from Frankfurt. German production of vaccine against typhus exanthematous for German army was managed by German physician--Herman Wohlrab. National Institute of Hygiene was to be a place modelled on Institute for Tropical Diseases in Hamburg. Polish personnel was subject to military regime, however Feliks Przesmycki, PhD started underground production of vaccine against typhus exanthematous for Polish citizens, which was distributed to prisons (Pawiak Prison) and ghetto. Hospital personnel in Warsaw was also vaccinated. Underground studies programme, including editing handbooks, was set up for the students of closed Microbiology Faculty of Warsaw University, and other wartime conspiracy actions were taken. Personnel of National Institute of Hygiene (PZH) protected research equipment and supplies from war plundering, and supported Polish civilians by e.g. reporting about harmfulness of low-quality and polluted food for the Polish, which Germans supplied market with. During Warsaw Uprising Personnel helped the injured and protected the premises of National Institute of Hygiene (PZH) from burning down; mobile army surgical hospital and pharmacy for the participans of Warsaw Uprising functioned within PZH.