ABSTRACT
In this case, we present imaging findings characteristic of chronic genitourinary schistosomiasis. Schistosoma haematobium, a blood fluke endemic to Africa and the Middle East, is a prominent cause of hematuria and bladder cancer in regions lacking adequate water sanitation. Luminal calcifications of the genitourinary tract, that is, of the bladder and/or ureters, from deposition of fluke eggs are a classic sign of chronic S. haematobium infection and should raise suspicion for the disease even when urine or serological tests are negative. It is important to recognize these findings on CT or, in resource-limited settings, plain film to allow for prompt, effective treatment.
Subject(s)
Dysuria/parasitology , Hematuria/parasitology , Schistosomiasis haematobia/complications , Adult , Female , HumansSubject(s)
Disease Outbreaks , Hematuria/etiology , Schistosoma haematobium/isolation & purification , Schistosomiasis haematobia/epidemiology , Abdominal Pain/etiology , Abdominal Pain/parasitology , Adolescent , Animals , Case-Control Studies , Child , Dysuria/etiology , Dysuria/parasitology , Female , Health Education/methods , Hematuria/parasitology , Humans , Male , Namibia/epidemiology , Risk Factors , Schistosomiasis haematobia/diagnosis , Schistosomiasis haematobia/prevention & control , Students , Young AdultABSTRACT
PURPOSE: The aim of this study was to evaluate the efficacy of Mentha crispa in the treatment of women with Trichomonas vaginalis infection (TVI). METHODS: This was a randomized, double-blind, and controlled clinical trial consisting of three phases, pre-treatment, treatment, and post-treatment. Sixty female patients were randomized to a treatment group, M. crispa (24 mg) or secnidazole (2,000 mg), both consisting of single dose. RESULTS: After treatment the proportion of patients without TVI in secnidazole group was 96.6% and in the M. crispa group was 90%, no difference was found between groups (P = 0.6120). We observed improvement in vaginal discharge, malodorous vaginal secretion, dyspareunia, dysuria, pelvic pain, and burning and itching in the genital area in patients of both groups of treatment, with no statistically significant differences between them (P > 0.05). Adverse effects were significantly higher (P = 0.0006) in the secnidazole group (66.6%) than in the M. crispa group (20%), that being mostly nausea and metallic taste with statistically significant differences between treatment groups (P < 0.001). CONCLUSION: This study is the first to show that M. crispa is effective and safe, representing an alternative for the treatment of TVI in women.
Subject(s)
Antitrichomonal Agents/therapeutic use , Mentha , Metronidazole/analogs & derivatives , Phytotherapy , Plant Extracts/therapeutic use , Trichomonas Vaginitis/drug therapy , Vaginal Discharge/parasitology , Adult , Antitrichomonal Agents/adverse effects , Double-Blind Method , Dyspareunia/parasitology , Dysuria/parasitology , Female , Humans , Male , Metronidazole/adverse effects , Metronidazole/therapeutic use , Middle Aged , Nausea/chemically induced , Pelvic Pain/parasitology , Plant Extracts/adverse effects , Pruritus/parasitology , Statistics, Nonparametric , Taste Disorders/chemically induced , Trichomonas vaginalis , Young AdultABSTRACT
BACKGROUND: Schistosomiasis is a parasitic infection affecting both adults and children. It occurs on contact with infected fresh water that harbours the intermediate host. It is a chronic disease and its urinary symptoms manifests as dysuria and haematuria. METHOD: This is a nine months prospective study of patients diagnosed and managed for urinary schistosomiasis at General Hospital Aliero, Nigeria from February to October 2006. The patients were followed up after presentation and commencement of therapy. RESULT: During the period of study, 35 patients were managed at the centre for urinary schistosomiasis. The patients presented with haematuria (13), dysuria (12), abdominal pain (4), fever (3), oliguria (2), polyuria (1), penile pain (1), and urethral discharge (1). The patients were managed with praziquantel. CONCLUSION: Haematuria and dysuria were the main symptoms of urinary schistosomiasis. There is need for mass treatment of schistosomiaisis in affected areas. Regular continuous education and campaign against schistosomiasis is necessary for control ofthe disease.