ABSTRACT
Eccrine glands are uniquely susceptible to a variety of pathologic processes. Alteration in the rate of sweat secretion manifests as hypohidrosis and hyperhidrosis. Obstruction of the eccrine duct leads to miliaria. The excretion of drugs into eccrine sweat may be a contributory factor in neutrophilic eccrine hidradenitis (NEH), syringosquamous metaplasia (SSM), coma bulla, and erythema multiforme (EM). Alterations in the electrolyte composition of eccrine sweat can be observed in several systemic diseases, most notably cystic fibrosis. This article summarizes current knowledge of eccrine gland pathophysiology.
Subject(s)
Adult , Child , Humans , Coma/chemically induced , Sweat Gland Diseases/etiology , Sweat Gland Diseases/physiopathology , Sweat Gland Diseases/chemically induced , Electrolytes/analysis , Erythema Multiforme/chemically induced , Cystic Fibrosis/metabolism , Eccrine Glands/physiopathology , Eccrine Glands/metabolism , Eccrine Glands/pathology , Hidradenitis/chemically induced , Hyperhidrosis/etiology , Hyperhidrosis/physiopathology , Hypohidrosis/etiology , Hypohidrosis/physiopathology , Metaplasia , Miliaria/etiology , Miliaria/physiopathology , Sweat/metabolism , Sweat/chemistry , Disease Susceptibility , Drug Therapy/adverse effects , Blister/chemically inducedABSTRACT
Se presenta el caso de un hombre de 47 anos a quien se le diagnostico un poroma ecrino maligno localizado en el dorso del pie derecho, con metastasis a region inguinal, pulmon, higado y sistema nervioso central, que le produjeron la muerte. Se discuten los hallazgos clinico e histopatologicos
We report on the case of a 47 year-old man with the diagnosis of malignant eccrine poroma, located on the right foot; he died from metastatic lesions affecting inguinal region, lungs, liver and central nervous system. Clinical and histopathologic findings are discussed .A review Is Included on sweat gland carcinomas.