1.
J Vet Med Sci
; 67(11): 1167-71, 2005 Nov.
Article
in English
| MEDLINE
| ID: mdl-16327230
ABSTRACT
Edema disease (ED) has become frequent in Japan, but no effective method for experimental infection has been developed. We report here the use of a capsule that resistant against gastric digestion to induce the ED in piglets. Four 21-day-old piglets were used. Shiga toxin 2e-producing Escherichia coli (STEC) cell pellet was encapsulated and administered orally. Two pigs received 1.0x10(10) CFU for two days, and the others received 3.9x10(8) CFU for three days. The high-dose group caused the typical clinical ED signs (palpebral edema or neurologic impairment). Eosinophil infiltration, swollen lymphoid follicles, and edema were observed in the ileum. The kidney had the thrombus in the glomerulus.
Subject(s)
Edema Disease of Swine/microbiology , Edema Disease of Swine/pathology , Escherichia coli Infections/veterinary , Intestines/pathology , Shiga Toxin 2/administration & dosage , Animals , Body Constitution , Body Weight , Diarrhea/etiology , Diarrhea/pathology , Edema Disease of Swine/complications , Escherichia coli Infections/complications , Escherichia coli Infections/pathology , Intestines/microbiology , Kidney/pathology , Swine
2.
Berl Munch Tierarztl Wochenschr
; 85(12): 221-4, 1972 Jun 15.
Article
in German
| MEDLINE
| ID: mdl-5047126