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1.
Cerebral acid hydrolases as indicators of the progress of viral encephalitis [proceedings].
Suckling, A J; Jagelman, S; Webb, H E.
Biochem Soc Trans ; 5(4): 1085-8, 1977.
Article in English | MEDLINE | ID: mdl-913788

Subject(s)
Acetylglucosaminidase/metabolism , Acid Phosphatase/metabolism , Arboviruses , Brain/enzymology , Encephalitis, Arbovirus/enzymology , Glucuronidase/metabolism , Hexosaminidases/metabolism , Animals , Encephalitis, Arbovirus/mortality , Lysosomes/enzymology , Mice
2.
Vascular and neuroglial changes in experimental herpes simplex encephalitis enzyme histochemical study.
Farkas-Bargeton, E; Diebler, M F; Kristensson, K; Lycke, E; Sourander, P.
Acta Neuropathol ; 33(1): 51-7, 1975 Oct 27.
Article in English | MEDLINE | ID: mdl-170779

ABSTRACT

An enzyme histochemical study of experimental herpes simplex encephalitis of the mouse has revealed a decrease in the number of capillaries displaying alkaline phosphatase activity. Glial cells showed increased Inosine 5 diphosphatase and ATPase activity. These enzyme histochemical changes were distributed throughout the nervous parenchyma while the lesions, seen by light microscopy, are localized to well defined areas. Mice inoculated with a pure culture of irradiated HSV failed to show the above mentioned modifications.


Subject(s)
Encephalitis, Arbovirus/enzymology , Herpes Simplex/enzymology , Neuroglia/enzymology , Adenosine Triphosphatases/metabolism , Alkaline Phosphatase/metabolism , Animals , Brain/blood supply , Capillaries/enzymology , Encephalitis, Arbovirus/pathology , Herpes Simplex/pathology , Histocytochemistry , Mice , Neuroglia/pathology , Radiation Effects , Simplexvirus/radiation effects
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