ABSTRACT
Verificar a associação da predição de lesão por pressão com os níveis de albumina, hematócrito ehemoglobina. Métodos: estudo documental, desenvolvido em uma Unidade de Terapia Intensiva para Adultoscom prontuários de pacientes elegíveis (n=255). Foram extraídas variáveis de caracterização sociodemográficae clínica, desenvolvimento de lesão por pressão e região; escore da escala de Braden e resultados dosmarcadores bioquímicos. Fez-se análise estatística descritiva e inferencial, adotando-se nível de significânciade 5,0%. Resultados: houve prevalência do sexo masculino (64,7%) e de pacientes cirúrgicos (69,8%). Nãohouve associação estatística significativa entre os marcadores de hematócrito e hemoglobina com a prediçãode lesão por pressão, diferentemente dos níveis de albumina (p=0,023). Conclusão: há associação de prediçãode lesão por pressão no que se refere à albumina. O aporte proteico do paciente deve ser visto com maior rigorpela equipe de saúde.
Objective: to verify the association of pressure injury prediction with albumin, hematocrit and hemoglobin levels. Methods: documentary study, developed in an Intensive Care Unit for Adults with records of eligible patients (n=255). Sociodemographic and clinical characterizations lesion, development of pressure injury and region; a score of the Braden scale and results of biochemical markers were extracted. There was a descriptive and inferential statistical analysis, adopting a significance level of 5.0%. Results: there was a prevalence of males (64.7%) and surgical patients (69.8%). There was no significant association between hematocrit and hemoglobin markers with the pressure injury prediction, unlike albumin levels (p=0.023). Conclusion: there is an injury pressure prediction association in the albumin. The protein intake of the patient should be seen in greater detail by the health team.
Subject(s)
Humans , Male , Female , Albumins/antagonists & inhibitors , Nutrition Assessment , Biomarkers , Biomarkers/chemistry , Nursing Care , Endophenotypes/chemistry , Patient Safety , Pressure Ulcer , Medical Records Department, HospitalABSTRACT
BACKGROUND: A new method of assessment of microvascular abnormality in living schizophrenic subjects via retinal imaging was described by Meier et al. (2013). The principal aim of this review is to summarise the relevant knowledge and suggest further avenues of research into this topic. SUBJECT AND METHODS: On 20th April 2015, we carried out a search using the computer database system PubMed by using keywords "microvascular AND schizophrenia". RESULTS: Out of the 17 articles found, only seven were relevant. They are generally consistent with the hypothesis of microvascular pathology and brain inflammation as part of the pathogenesis in schizophrenia. It is important to stress that all studies of brain microvasculature in schizophrenia to date have been post mortem findings, apart from the work by Meier et al. (2013) which is related to retinal imaging in living subjects. CONCLUSIONS: Based on the literature, we suggest the following research and clinical avenues: Firstly, to assess whether microvascular abnormality found via retinal imaging, fulfils the criteria for the schizophrenia endophenotype. Secondly, to examine retinal imaging in high-risk individuals for schizophrenia. Thirdly, to determine whether the fMRI findings and cognitive abilities of schizophrenia patients in both longitudinal as well as cross-sectional studies, is associated with the microvascular abnormalities assessed by the retinal imaging. Fourthly, to determine if there is a correlation between microvascular retinal pathology and the positive or negative schizophrenia symptoms. Furthermore, to determine if childhood maltreatment results in any abnormities in retinal imaging. Lastly, to analyse the genetic background of schizophrenia retinal microvascular pathology and to apply anti-inflammatory agents in the treatment and prevention of schizophrenia if brain vasculitis is confirmed.