Effects of different levels of two types of olive pulp with or without exogenous enzyme supplementation on broiler performance and economic parameters

The effects of the dietary inclusion of olive pulp (OP) and supplementation birds with a commercial enzyme blend (ENZ) on the performance of broilers were evaluated. Six hundred one-day-old male Ross 308 broilers were divided according to a completely randomized design into 10 treatments in a 2×2×2+2 factorial arrangement, consisting of two olive pulp levels (50 and 100 g/kg diet), two pulp categories (processed and non-processed), the inclusion or not of an enzyme blend supplement, and two control treatments without OP and the inclusion or not of the enzyme blend in the diet. Feed intake (FI), weight gain (WG), feed efficiency (FE), energy intake (EI), energy efficiency (EE), protein intake (PI), protein efficiency (PE), feed cost per kg live weight (FC/kg), and production index (IP) were determined. There was no significant difference (p> 0.05) between broilers fed the OP diets and the control diets for all parameters. Processed OP improved FE (p 0.019 from 1-21 days; p 0.005 from 22-42 days; and p 0.008 from 1-42 days of age) and EE (p 0.05) any of the studied variables. The inclusion of OP in the diets at levels up to 100g/kg would does not have deleterious effects on broiler production performance.

Effects of different levels of two types of olive pulp with or without exogenous enzyme supplementation on broiler performance and economic parameters

The effects of the dietary inclusion of olive pulp (OP) and supplementation birds with a commercial enzyme blend (ENZ) on the performance of broilers were evaluated. Six hundred one-day-old male Ross 308 broilers were divided according to a completely randomized design into 10 treatments in a 2×2×2+2 factorial arrangement, consisting of two olive pulp levels (50 and 100 g/kg diet), two pulp categories (processed and non-processed), the inclusion or not of an enzyme blend supplement, and two control treatments without OP and the inclusion or not of the enzyme blend in the diet. Feed intake (FI), weight gain (WG), feed efficiency (FE), energy intake (EI), energy efficiency (EE), protein intake (PI), protein efficiency (PE), feed cost per kg live weight (FC/kg), and production index (IP) were determined. There was no significant difference (p> 0.05) between broilers fed the OP diets and the control diets for all parameters. Processed OP improved FE (p 0.019 from 1-21 days; p 0.005 from 22-42 days; and p 0.008 from 1-42 days of age) and EE (p <= 0.012 from 1-21 days; p <=0.012 from 22-42 days; and p <= 0.002 from 1-42 days of age). The enzyme blend supplementation did not influence (p> 0.05) any of the studied variables. The inclusion of OP in the diets at levels up to 100g/kg would does not have deleterious effects on broiler production performance.(AU)

Cyclooxygenase-2 expression in epithelial neoplasms and its relevance as a targeted therapy in dogs / Expressão de ciclooxigenase-2 em neoplasias epiteliais e sua relevância como terapia alvo em cães

Targeted therapy of neoplasms is an emergent approach in human and veterinary medicine. Cyclooxygenase (COX) is a class of catalytic enzymes related to the formation of inflammatory mediators. COX-2 is expressed constitutively in a few body tissues, but it may be induced in specific pathophysiologic conditions, such as cancer. COX-2 expression in neoplams may be considered a potential predictive factor, due to the possible association of selective COX-2 inhibitors in adjuvant treatments. This scientific communication has the objective to report COX-2 expression in seven neoplasms of dogs and the usage of adjuvant treatment with COX-2 selective inhibitors as an effective and feasible option in cancer treatment.(AU)

O tratamento direcionado das neoplasias é uma abordagem emergente tanto na medicina humana, quanto na veterinária. A cicloxigenase (COX) é uma classe de enzimas catalíticas relacionada à formação de mediadores inflamatórios. A COX-2é expressa de forma constitutiva em poucos tecidos, mas pode ser induzida em condições patofisiológicas específicas, como os processos neoplásicos. A expressão da COX-2 em neoplasias pode ser considerada um fator preditivo em potencial, tendo em vista a possibilidade de associação de inibidores seletivos para COX-2 em tratamentos adjuvantes. Esta comunicação científica teve como objetivo relatar a expressão de COX-2 em neoplasias de sete cães e o tratamento adjuvante com inibidores seletivos para COX-2 como uma opção efetiva e viável no tratamento do câncer.(AU)