ABSTRACT
A 9 yr old castrated male golden retriever weighing 36 kg was presented for evaluation of progressive left pelvic limb paresis and fecal and urinary incontinence. MRI demonstrated an extradural, ovoid mass compressing the lumbar spinal cord. Surgical excision of the mass was performed. Histologically, the mass was consistent with hemangiosarcoma with no involvement of the adjacent vertebrae. The dog underwent a doxorubicin-based chemotherapy protocol with the addition of oral cyclophosphamide. After completion of chemotherapy, the dog was evaluated q 4 mo for restaging. Clinicopathological evidence of primary tumor recurrence or metastatic disease was not detected for 15 mo after initial diagnosis and treatment. To the authors' knowledge, this is the first report of a primary extradural hemangiosarcoma in the lumbar vertebral column in a dog. The clinical presentation, diagnosis, treatment, and outcome are also discussed.
Subject(s)
Antineoplastic Agents/therapeutic use , Dog Diseases/diagnosis , Epidural Neoplasms/veterinary , Hemangiosarcoma/veterinary , Animals , Dog Diseases/drug therapy , Dogs , Epidural Neoplasms/diagnosis , Epidural Neoplasms/drug therapy , Hemangiosarcoma/diagnosis , Hemangiosarcoma/drug therapy , Lumbar Vertebrae , MaleABSTRACT
Epidural spinal myelolipoma was diagnosed in an 11.5-year-old castrated male Husky-cross that was evaluated at the veterinary teaching hospital due to progressive thoracolumbar spinal hyperaesthesia and mild proprioceptive pelvic limb ataxia. A focal, ill-defined mildly inhomogenous extradural mass lesion was detected by MRI. The dog was euthanized. At necropsy an extradurally located reddish mass of about 2.5 cm in diameter was present in the vertebral canal. The mass was identified histopathologically as an epidural myelolipoma.
Subject(s)
Dog Diseases/pathology , Epidural Neoplasms/veterinary , Myelolipoma/veterinary , Animals , Dogs , Epidural Neoplasms/pathology , Male , Myelolipoma/pathologyABSTRACT
Epidural spinal myelolipoma was diagnosed in a 13-year-old, male Siberian husky that was referred for evaluation of progressive pelvic limb paresis and urinary incontinence. An epidural mass was detected by magnetic resonance imaging and computed tomography. The mass was removed and identified histopathologically as an epidural myelolipoma. Pelvic limb paresis improved after surgery, but urinary retention associated with neurological bladder dysfunction persisted.
Subject(s)
Adrenal Gland Neoplasms/veterinary , Dog Diseases/surgery , Epidural Neoplasms/veterinary , Myelolipoma/veterinary , Paresis/veterinary , Adrenal Gland Neoplasms/complications , Adrenal Gland Neoplasms/diagnosis , Adrenal Gland Neoplasms/surgery , Animals , Dog Diseases/diagnosis , Dog Diseases/etiology , Dog Diseases/pathology , Dogs , Epidural Neoplasms/complications , Epidural Neoplasms/diagnosis , Epidural Neoplasms/surgery , Laminectomy/veterinary , Magnetic Resonance Imaging/veterinary , Male , Myelolipoma/complications , Myelolipoma/diagnosis , Myelolipoma/surgery , Paresis/etiology , Tomography, X-Ray Computed/veterinary , Treatment Outcome , Urinary Bladder, Neurogenic/etiology , Urinary Bladder, Neurogenic/veterinary , Urinary Incontinence/etiology , Urinary Incontinence/veterinary , Urinary Retention/etiology , Urinary Retention/veterinaryABSTRACT
A 5-year-old dog developed neurologic signs of thoracolumbar spinal cord dysfunction. The presence of an epidural mass which affected the electromyogram of the T-13 to L-3 spinal segments was demonstrated by myelography. Surgical removal was attempted. Examination of frozen and formalin-fixed tissues revealed the mass to be a chondrosarcoma. Doxorubicin hydrochloride was given every third week for a total of 6 doses following surgery. No signs of recurrence or metastases have been found for over 6 months. The differential diagnosis of epidural masses should include chondrosarcoma, even in the absence of vertebral lesions on plain radiographs, as in this case. Rapid diagnosis and aggressive therapy may have improved the prognosis.
