Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 7 de 7
Filter
Add more filters










Database
Publication year range
1.
Clin Otolaryngol ; 35(2): 104-10, 2010 Apr.
Article in English | MEDLINE | ID: mdl-20500579

ABSTRACT

OBJECTIVES: Based on our hypothesis that biofilm is nothing else but normal, otherwise abundantly colonised mucosal mucous blanket, the aim of this study was to check out whether bacterial biofilm exists exclusively at the diseased mucosal surfaces or at healthy mucosa of paranasal sinuses as well. DESIGN: Prospective and blinded. SETTING: Tertiary academic hospital. PARTICIPANTS: The patients suffering from the diseases not related to the chronic inflammation of the paranasal sinuses. Mucosal tissue samples from healthy sphenoid sinuses were taken from 48 patients who underwent pituitary gland surgery and from ethmoidal sinuses mucosa of the 17 patients who underwent endonasal endoscopic orbital decompression because of Graves' disease. MAIN OUTCOME MEASURES: The samples were submitted blindly along with similar samples from patients with chronic rhinosinusitis to two scanning electron microscope experts. In all samples the looked for the main signs of biofilm presence of: the 'towers', rod-shaped bacteria and water channels. RESULTS: Signs of biofilm presence were found in 45 out of 48 pituitary gland surgery patients (94%) and in all of 17 EEOD patients (100%). CONCLUSIONS: Our study showed the presence of the biofilm at the surface of the healthy mucosa of the paranasal sinuses. This suggests that perhaps so called bacterial biofilm is nothing else but regular respiratory mucosal blanket, a part of the mucociliary system itself, containing a great number of bacteria.


Subject(s)
Biofilms , Ethmoid Sinus/physiology , Ethmoid Sinus/ultrastructure , Nasal Mucosa/physiology , Nasal Mucosa/ultrastructure , Rhinitis/complications , Sinusitis/complications , Adult , Aged , Double-Blind Method , Endoscopy/methods , Ethmoid Sinus/microbiology , Female , Humans , Male , Microscopy, Electron/methods , Middle Aged , Nasal Mucosa/microbiology , Prospective Studies , Pseudomonas Infections/complications , Pseudomonas aeruginosa/isolation & purification , Rhinitis/microbiology , Rhinitis/surgery , Sinusitis/microbiology , Sinusitis/surgery , Young Adult
2.
Lin Chuang Er Bi Yan Hou Ke Za Zhi ; 11(5): 206-8, 1997 May.
Article in Chinese | MEDLINE | ID: mdl-9812798

ABSTRACT

The ultrastructures of the uncinate processes (UP) obtainel from 16 patients with clinical diagnosis of chronic sinusitis were observed by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The results showed that there were three main surface cell types on the UP: Most of the cilia was leaned, fractured and in disorder; Gaps of the cells increased obviously; Squamous cell metaplasia was seen; The endoplasmic reticulums and mitochondria in cytoplasm were expanded moderatly or seriously. The morphological changes indicated that mucus transportation functions in the anterior ethmoid region and the middle meatus were damaged. It is of great importance in occurrence and development of chronic sinusitis. The demaged nasal mucosa epithlial cells are repairable and reproducible.


Subject(s)
Ethmoid Sinus/ultrastructure , Sinusitis/pathology , Adult , Chronic Disease , Cilia/ultrastructure , Female , Humans , Male , Middle Aged
3.
Zhonghua Er Bi Yan Hou Ke Za Zhi ; 32(6): 363-5, 1997 Dec.
Article in Chinese | MEDLINE | ID: mdl-10743114

ABSTRACT

To provide further understanding of uncinate process, 15 uncinate processes were examined under scanning electron microscope, and 32 high-resolution coronal CT scans were studied in patients with septal deformity or sinusitis. It was found that(1)pathological ultrastructural changes of uncinate process were noted in patients with chronic sinusitis; (2) medially deviated, laterally deviated, pneumatization and hypertrophy of uncinate process were demonstrated. The following conclutions were drawn(1)the anatomic variations in ostiomeatal complex is responsible for the formation of chronic sinusitis; (2)for patients with chronic sinusitis, uncinatectomy is the treatment of choice; (3)preoperative and intraoperative studies of CT scans are mandatory for avoidance of complications.


Subject(s)
Ethmoid Bone/ultrastructure , Ethmoid Sinus/ultrastructure , Sinusitis/diagnostic imaging , Sinusitis/pathology , Adolescent , Adult , Female , Humans , Male , Middle Aged , Nasal Cavity/ultrastructure , Tomography, X-Ray Computed
4.
Laryngoscope ; 104(3 Pt 1): 364-9, 1994 Mar.
Article in English | MEDLINE | ID: mdl-8127195

ABSTRACT

The uncinate process (UP) has become a familiar anatomical landmark to otolaryngologists due to the increasing popularity of functional endoscopic sinus surgery (FESS) in recent years. This study examines the histological and morphological features of UPs removed from a group of patients undergoing FESS operations for chronic sinusitis. The structure of the UP by light microscopy (LM) is reported. A relatively high proportion of goblet cells and seromucous glands was noted. Scanning electron microscopy (SEM) identified four surface cell types on the UP. Furthermore, four categories of surface morphology were noted. The most common appearance was of predominantly ciliated cells. A nonciliated surface ultrastructure is associated with a longer history of sinonasal symptoms and a higher incidence of surgical intervention.


Subject(s)
Ethmoid Bone/pathology , Ethmoid Sinus/pathology , Ethmoid Sinusitis/pathology , Adult , Chronic Disease , Ethmoid Bone/ultrastructure , Ethmoid Sinus/ultrastructure , Ethmoid Sinusitis/surgery , Female , Humans , Male , Microscopy, Electron, Scanning , Middle Aged
5.
Zentralbl Veterinarmed A ; 39(8): 609-15, 1992 Oct.
Article in English | MEDLINE | ID: mdl-1455929

ABSTRACT

A histopathological, morphometric and ultrastructural study was made of enzootic nasal neoplasia in a group of 25 Verata goats. A nasal adenocarcinoma was diagnosed. The neoplasm contained two clearly defined zones, one cystic and the other compact. The tumour stroma was composed of abundant loose connective tissue, in which mononuclear infiltrate was clearly identifiable. The observed viral particles were morphologically similar to Visna-Maedi. These particles had an eccentrically located electrodense core. The diameter of the virus was about 90 nm and it showed envelope numerous spikes on the surface. The virus is assumed to be the causative primary agent of the tumour.


Subject(s)
Adenocarcinoma/veterinary , Ethmoid Sinus/pathology , Goat Diseases/pathology , Paranasal Sinus Neoplasms/veterinary , Virion/ultrastructure , Adenocarcinoma/microbiology , Adenocarcinoma/pathology , Animals , Ethmoid Sinus/ultrastructure , Goat Diseases/microbiology , Goats , Paranasal Sinus Neoplasms/microbiology , Paranasal Sinus Neoplasms/pathology
6.
J Laryngol Otol ; 104(7): 570-3, 1990 Jul.
Article in English | MEDLINE | ID: mdl-2384715

ABSTRACT

Extraskeletal Ewing's sarcoma is rarely found arising in the head and neck region. An unusual case arising in the nasal fossa in a young child is reported and the differential diagnosis, pathology and treatment discussed.


Subject(s)
Ethmoid Sinus/ultrastructure , Nose Neoplasms/ultrastructure , Paranasal Sinus Neoplasms/ultrastructure , Sarcoma, Ewing/ultrastructure , Child , Humans , Male , Nasal Cavity , Orbit/ultrastructure
7.
Vet Pathol ; 16(2): 180-90, 1979 Mar.
Article in English | MEDLINE | ID: mdl-442448

ABSTRACT

In five cases of endemic ethmoidal carcinoma in cattle from the Dominican Republic three tumor types could be classified: undifferentiated carcinoma (3), adenocarcinoma (1), and squamous cell carcinoma (1). Electron microscopy showed that the tumor cells in undifferentiated carcinomas closely resembled the cells of the normal olfactory mucosa. This was especially true for the dark cells of Bowman's gland. Ultrastructurally, the lymphoid cells of the undifferentiated bovine carcinoma resembled the lymphoid cells of human nasopharyngeal carcinoma being closely associated with Epstein-Barr Virus. This and epidemiological observations suggested a viral cause of endemic ethmoidal carcinoma.


Subject(s)
Cattle Diseases/pathology , Ethmoid Sinus , Paranasal Sinus Neoplasms/veterinary , Adenocarcinoma/ultrastructure , Adenocarcinoma/veterinary , Animals , Carcinoma/ultrastructure , Carcinoma/veterinary , Carcinoma, Squamous Cell/ultrastructure , Carcinoma, Squamous Cell/veterinary , Cattle , Cattle Diseases/epidemiology , Cattle Diseases/etiology , Dominican Republic , Ethmoid Sinus/pathology , Ethmoid Sinus/ultrastructure , Paranasal Sinus Neoplasms/epidemiology , Paranasal Sinus Neoplasms/ultrastructure , Virus Diseases/veterinary
SELECTION OF CITATIONS
SEARCH DETAIL
...