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1.
J Drugs Dermatol ; 18(1): 67-74, 2019 01 01.
Article in English | MEDLINE | ID: mdl-30681799

ABSTRACT

Objective: To study the safety, efficacy, optimal volume, and longevity of an injectable hyaluronic acid (HA) gel dermal filler to treat facial temporal fossa fat loss. Methods and materials: This open-label, single-site, 12-month study used 20 mg/mL HA gel to correct volume loss in both temples in 30 subjects. Touch-ups were allowed at week 2. At each visit, the investigator completed a Frontal Temporal Fossa Scale and a 7-point satisfaction scale. Subjects completed a 7-point satisfaction scale, Subject Global Aesthetic Improvement Scale (GAIS), and self-perception of age assessment. Photos were taken at each visit. Results: Subjects who returned for the one-month visit (29) achieved a ≥ 1-point improvement on the Temporal Fossa Scale in both temples. At month 12, 98% of the temples maintained a ≥ 1-grade, 18% showed a 3-grade, 34% showed a 2-grade, and 46% showed a 1-grade improvement. All subjects received an average of 1.1 mL per temple. Mild to moderate jaw pain after injections was noted by 40% of patients. The pain was reported to occur during mastication. There was no correlation between the amount of the study device injected and the incidence of jaw pain, which did not occur at the touch-up injections and was self-limited. Injections were well tolerated, and no patients developed vascular compromise, vascular events, or visual disturbances. Conclusion: HA gel (20 mg/mL) is safe and efficacious when used in the facial temporal fossa. The results lasted at least 12 months in 98% of subjects. Most subjects perceived themselves as looking younger than at baseline. J Drugs Dermatol. 2019;18(1):67-74.


Subject(s)
Dermal Fillers/therapeutic use , Facial Dermatoses/drug therapy , Hyaluronic Acid/therapeutic use , Patient Satisfaction , Skin Aging , Adult , Aged , Cosmetic Techniques , Dermal Fillers/administration & dosage , Ethnicity , Facial Dermatoses/ethnology , Female , Gels , Humans , Hyaluronic Acid/administration & dosage , Male , Middle Aged , Rejuvenation , Surveys and Questionnaires , Treatment Outcome
2.
Dermatology ; 235(2): 112-119, 2019.
Article in English | MEDLINE | ID: mdl-30466093

ABSTRACT

BACKGROUND: Various facial and extrafacial lesions have been reported in frontal fibrosing alopecia (FFA). Facial papules have been associated with worse prognosis. OBJECTIVES: We sought to detect the prevalence of facial and extrafacial lesions and to analyze their relation to demographic and clinical variables in a large and ethnically diverse series of patients with FFA. METHODS: Charts of patients diagnosed with FFA between January 1, 2015, and December 31, 2017, at the Department of Dermatology, University of Miami, were reviewed retrospectively. RESULTS: 91 patients (87 women and 4 men) met inclusion criteria: 45% (n = 41) were of Hispanic/Latino ethnicity, and 34% (n = 30) were premenopausal. Facial papules were most commonly detected (41% among Hispanic/Latino patients). Significant associations were found between: (1) Hispanic/Latino ethnicity and any FFA-associated facial lesions, facial papules alone, or lichen planus pigmentosus alone, as well as premenopausal status; (2) any FFA-associated facial lesions or facial papules alone and premenopausal status; and (3) Hispanic/Latino ethnicity and simultaneous presence of facial and extrafacial lesions. CONCLUSIONS: There is a significant association among Hispanic/Latino ethnicity, facial papules, and premenopausal status, which may portend a susceptibility to severer disease and prompt early and aggressive treatment in this group.


Subject(s)
Alopecia/ethnology , Facial Dermatoses/ethnology , Hispanic or Latino , Premenopause , Skin/pathology , Adult , Black or African American , Aged , Aged, 80 and over , Asian , Comorbidity , Extremities , Female , Fibrosis , Florida , Humans , Lichen Planus/ethnology , Male , Middle Aged , Neck , Retrospective Studies , Torso , White People
3.
Photomed Laser Surg ; 36(1): 37-43, 2018 Jan.
Article in English | MEDLINE | ID: mdl-28994643

ABSTRACT

OBJECTIVE: To compare the safety and efficacy of pulsed dye laser (PDL) at different intervals for the treatment of East Asians with Port-Wine Stain (PWS). BACKGROUND: The population of East Asians around the world is about 1.6 billion, and they are considered to have more melanin in their skin compared with Caucasians. Nevertheless, no studies about the optimal treatment intervals for East Asians with PWS have been carried out. METHODS: We prospectively investigated 39 East Asian patients with untreated PWS. Half of the PWS lesion was randomly allocated to be treated at 3 weeks and the other half at 6 weeks. Both halves of the PWS were treated three times in total. The efficacy outcome 2 months post final treatment was evaluated by visual and chromameter evaluation. RESULTS: The average blanching rate was 40.27% and 44.17% for PDL treatments at the 3- and 6-week interval sites, respectively (p > 0.05). No patient developed scarring or permanent pigmentation change. LIMITATIONS: There was no age criteria involved in the enrollment of patients in this study. Additionally, there is no comparison with long-term treatments at different intervals. CONCLUSIONS: PDL treatment at 3-week interval proved to be safe for East Asians with PWS. This can reduce the total duration of the course of treatments and had no increase in side effects compared with the standard interval treatments.


Subject(s)
Lasers, Dye/therapeutic use , Low-Level Light Therapy/methods , Patient Safety , Port-Wine Stain/ethnology , Port-Wine Stain/radiotherapy , Adolescent , Child , Child, Preschool , Cohort Studies , Facial Dermatoses/diagnosis , Facial Dermatoses/ethnology , Facial Dermatoses/radiotherapy , Asia, Eastern , Female , Humans , Infant , Male , Port-Wine Stain/diagnosis , Prognosis , Prospective Studies , Statistics, Nonparametric , Time Factors , Treatment Outcome , Young Adult
4.
Dermatol Surg ; 43(9): 1137-1143, 2017 Sep.
Article in English | MEDLINE | ID: mdl-28746258

ABSTRACT

BACKGROUND: Fractional carbon dioxide (CO2) laser resurfacing unites the idea of fractional photothermolysis with an ablative 10,600-nm wavelength. This technology permits effective treatment of acne scarring, with shorter recovery and a decreased side effect profile as compared to traditional CO2 laser resurfacing. OBJECTIVE: The aims of this study were to study the efficacy and safety of fractional CO2 laser for acne scars in Asian patients. METHODS: This was a retrospective study of all patients treated with the fractional CO2 laser for facial acne scarring between January 2, 2008, and December 31, 2010, at the National Skin Centre, Singapore. Data reviewed included sex, age, and severity of acne, type of scarring, previous treatment history, frequency of treatments, adverse events, and efficacy. RESULTS: Two hundred and ten fractional CO2 laser treatments for facial acne scars were performed on 107 patients (65 men and 42 women, Fitzpatrick skin Types II to V) during the study period. Sixteen of 107 patients experienced (15.0%) adverse events. The adverse events include hyperpigmentation (6.4%), blistering (4.0%), crusting (2.9%), aggravation of inflammatory acne lesions (1.7%), and scarring (0.6%). There were no reported side effects of hypopigmentation, bacterial or viral infection. Follow-up results after final laser treatment showed that 66.4% of patients reported Grade 1 skin texture improvement, that is, <25% (n = 71); 30.0% had Grade 2 improvement, that is, 25% to 50% improvement (n = 31); 3.7% had Grade 3 improvement, that is, 51% to 75% improvement (n = 4); and 0.9% had Grade 4 improvement, that is, >75% improvement (n = 1). CONCLUSION: The study demonstrated the efficacy and safety of a fractional CO2 laser in the treatment of acne scars in Asian. Future studies are required to establish optimum treatment parameters and achieve better clinical results.


Subject(s)
Acne Vulgaris/complications , Asian People , Cicatrix/ethnology , Cicatrix/radiotherapy , Facial Dermatoses/ethnology , Facial Dermatoses/radiotherapy , Lasers, Gas/therapeutic use , Low-Level Light Therapy , Acne Vulgaris/ethnology , Adult , Cicatrix/etiology , Facial Dermatoses/etiology , Female , Humans , Lasers, Gas/adverse effects , Low-Level Light Therapy/adverse effects , Male , Middle Aged , Retrospective Studies , Young Adult
5.
Skin Res Technol ; 23(4): 613-618, 2017 Nov.
Article in English | MEDLINE | ID: mdl-28568473

ABSTRACT

BACKGROUND/PURPOSE: Facial skin hyperpigmention caused by chronic sun exposure is a major skin complaint, however, its characteristics and influential factors are still limitedly known. METHODS: A cross-sectional survey in healthy Japanese women aged from 6 to 62 years (n=169) was conducted using a facial image analyzer VISIA™ for knowing onset age of hyperpigmented spot formation, its chronological changes, and influence of environmental factors. RESULTS: UV Pigmented Spot (PS) Score was positively correlated with age (R=.487, P=.000). Hyperpigmented spots appeared first around 18 years old in most subjects, and PS score remarkably increased at 20s then gradually increased by ages. The subjects with Skin Type I, one of the three grades of Japanese Skin Type (JST), whose melanin formation is genetically lower, showed higher PS score. A woman aged 31 years was subjected a weekly VISIA measurement for 2 years, and found no changes in the number, place, size and intensity of the pigment spots in this duration. CONCLUSION: Hyperpigmented spots developed in women over 20 years of age due to chronic sun exposure without sun protection during childhood and adolescent and it was stable afterwards, whose intensity was influenced by age and skin type.


Subject(s)
Facial Dermatoses/etiology , Hyperpigmentation/etiology , Skin Aging/physiology , Adolescent , Adult , Age Distribution , Child , Cross-Sectional Studies , Diet , Environment , Facial Dermatoses/ethnology , Female , Humans , Hyperpigmentation/ethnology , Japan/ethnology , Life Style , Middle Aged , Skin Aging/ethnology , Sunlight , Ultraviolet Rays , Young Adult
6.
J Am Acad Dermatol ; 75(2): 385-92, 2016 Aug.
Article in English | MEDLINE | ID: mdl-27206758

ABSTRACT

BACKGROUND: Melasma is a common pigmentary disorder among Asians and treatment is challenging. Oral tranexamic acid (TA) has emerged as a potential treatment for refractory melasma. Large-scale studies on its use, outcomes, and safety are limited. OBJECTIVE: We sought to evaluate treatment outcomes and adverse effects of oral TA in melasma in an Asian population. METHODS: We conducted a retrospective analysis of patients who received oral TA for melasma in a tertiary dermatologic center from January 2010 to June 2014. RESULTS: In all, 561 patients (91.4% female, 8.6% male) were enrolled. Median duration of treatment was 4 months. The majority (503 [89.7%]) improved, 56 (10.0%) had no improvement, and 2 (0.4%) worsened. Patients without family history of melasma had better response rates than those with family history (90.6% vs 60.0%, P = .01). Of the 503 who improved, response was seen within 2 months of TA initiation, with a relapse rate of 27.2%. Adverse events occurred in 40 (7.1%). Most were transient, but 1 developed deep vein thrombosis requiring prompt discontinuation. She was later given the diagnosis of familial protein S deficiency. LIMITATIONS: This was a retrospective study. CONCLUSION: Oral TA may be an effective adjunct for refractory melasma. Careful screening for personal and familial risk factors for thromboembolism should be done before initiation.


Subject(s)
Dermatologic Agents/therapeutic use , Facial Dermatoses/drug therapy , Melanosis/drug therapy , Tranexamic Acid/therapeutic use , Administration, Oral , Adult , Asian People , Dermatologic Agents/adverse effects , Facial Dermatoses/ethnology , Female , Gastrointestinal Diseases/chemically induced , Headache/chemically induced , Humans , Male , Melanosis/ethnology , Middle Aged , Recurrence , Retrospective Studies , Risk Factors , Singapore , Tranexamic Acid/adverse effects , Treatment Outcome , Venous Thrombosis/chemically induced
8.
An Bras Dermatol ; 89(4): 576-9, 2014.
Article in English | MEDLINE | ID: mdl-25054743

ABSTRACT

BACKGROUND: Acne vulgaris has high prevalence, disturbing quality of life during adolescence. OBJECTIVES: To measure dissastifaction and acne in 18-year-old male individuals and its associated factors. METHODS: A questionnaire was applied by trained interviewers to all boys during selection for the military service. Dissatisfaction and acne was evaluated using a self-administered face scale. Facial, prestrernal and dorsal acne were evaluated separately. RESULTS: A total of 2,200 adolescents, aged 18 years, were interviewed. Among these, 1,678 had acne on the face and 974 (54.05%) showed some degree of dissatisfaction. Regarding the impact of acne located on the chest, 326 out of 686 adolescents (47.52%) reported dissatisfaction. For acne located on the back, 568 out of 1,103 affected individuals (51.50%) showed dissatisfaction. Facial / dorsal acne and dissatisfaction were statistically associated with lower income, lower education levels and with non-whites. Presternal acne and dissatisfaction were statistically asssociated with lower income and lower education levels. CONCLUSION: This population-based study found a high prevalence of acne on the face, back and chest, with high rates of dissatisfaction.


Subject(s)
Acne Vulgaris/epidemiology , Acne Vulgaris/psychology , Acne Vulgaris/ethnology , Adolescent , Back , Brazil/epidemiology , Emotions , Facial Dermatoses/epidemiology , Facial Dermatoses/ethnology , Facial Dermatoses/psychology , Humans , Male , Prevalence , Quality of Life/psychology , Risk Factors , Severity of Illness Index , Socioeconomic Factors , Surveys and Questionnaires , Thoracic Wall
10.
An. bras. dermatol ; 89(4): 576-579, Jul-Aug/2014. tab, graf
Article in English | LILACS | ID: lil-715533

ABSTRACT

BACKGROUND: Acne vulgaris has high prevalence, disturbing quality of life during adolescence. OBJECTIVES: To measure dissastifaction and acne in 18-year-old male individuals and its associated factors. METHODS: A questionnaire was applied by trained interviewers to all boys during selection for the military service. Dissatisfaction and acne was evaluated using a self-administered face scale. Facial, prestrernal and dorsal acne were evaluated separately. RESULTS: A total of 2,200 adolescents, aged 18 years, were interviewed. Among these, 1,678 had acne on the face and 974 (54.05%) showed some degree of dissatisfaction. Regarding the impact of acne located on the chest, 326 out of 686 adolescents (47.52%) reported dissatisfaction. For acne located on the back, 568 out of 1,103 affected individuals (51.50%) showed dissatisfaction. Facial / dorsal acne and dissatisfaction were statistically associated with lower income, lower education levels and with non-whites. Presternal acne and dissatisfaction were statistically asssociated with lower income and lower education levels. CONCLUSION: This population-based study found a high prevalence of acne on the face, back and chest, with high rates of dissatisfaction. .


Subject(s)
Adolescent , Humans , Male , Acne Vulgaris/epidemiology , Acne Vulgaris/psychology , Acne Vulgaris/ethnology , Back , Brazil/epidemiology , Emotions , Facial Dermatoses/epidemiology , Facial Dermatoses/ethnology , Facial Dermatoses/psychology , Prevalence , Quality of Life/psychology , Risk Factors , Severity of Illness Index , Socioeconomic Factors , Surveys and Questionnaires , Thoracic Wall
11.
J Eur Acad Dermatol Venereol ; 28(10): 1286-91, 2014 Oct.
Article in English | MEDLINE | ID: mdl-24118351

ABSTRACT

BACKGROUND: Erythromelanosis follicularis faciei (EFF) is clinically characterized by well-demarcated erythema, hyperpigmentation and follicular papules. No satisfactory therapy has been widely accepted. OBJECTIVE: This study was aimed to evaluate the efficiency and complications of a dual-wavelength laser system in the treatment of EFF in Chinese population. METHODS: Twelve Chinese patients with EFF were enrolled in this study. One side of the face was randomized to receive five successions of treatments at intervals of 6-8 weeks, with the other side spared as control. The parameters were set as follows: energy densities of 6.5-7.5 J/cm(2) with pulsed dye laser (PDL) and 35-50 J/cm(2) with Nd:YAG; pulse duration of 0.5 ms with PDL and 15 ms with Nd:YAG; a delay time of 100 ms between delivery of the two wavelengths. The efficacy was evaluated using subjective assessment and non-invasive measurement. RESULTS: After five sessions of treatment, over 40% patients achieved more than 50% (moderate or significant) improvement. The efficacy maintained at 3-month follow-up. The values of erythema index and melanin index on treated side were significantly less than those on untreated side after sessions of treatments. Adverse effects of treated side were limited. CONCLUSION: Using this split-face module, dual-wavelength laser system treatment is proved to be suitable for Chinese EFF. Adverse effects were minimal.


Subject(s)
Erythema/surgery , Facial Dermatoses/surgery , Laser Therapy , Lasers, Dye/therapeutic use , Lasers, Solid-State/therapeutic use , Melanosis/surgery , Adult , Asian People/ethnology , China/epidemiology , Double-Blind Method , Erythema/ethnology , Erythema/pathology , Facial Dermatoses/ethnology , Facial Dermatoses/pathology , Female , Follow-Up Studies , Humans , Incidence , Male , Melanosis/ethnology , Melanosis/pathology , Middle Aged , Retrospective Studies , Time Factors , Treatment Outcome , Young Adult
12.
Br J Dermatol ; 169 Suppl 3: 41-56, 2013 Oct.
Article in English | MEDLINE | ID: mdl-24098900

ABSTRACT

By midcentury, the U.S.A. will be more ethnically and racially diverse. Skin of colour will soon constitute nearly one-half of the U.S. population, and a full understanding of skin conditions that affect this group is of great importance. Structural and functional differences in the skin, as well as the influence of cultural practices, produce variances in skin disease and presentation based on skin type. In the skin of colour population, dyschromia is a growing concern, and a top chief complaint when patients present to the physician. A thorough understanding of the aetiology and management strategies of facial hyperpigmentation is of importance in caring for those afflicted and also in the development of new therapies.


Subject(s)
Facial Dermatoses/etiology , Hyperpigmentation/etiology , Administration, Cutaneous , Alphavirus Infections/complications , Alphavirus Infections/ethnology , Chikungunya Fever , Dermabrasion/methods , Dermatologic Agents/therapeutic use , Drug Combinations , Facial Dermatoses/ethnology , Facial Dermatoses/therapy , Humans , Hyperpigmentation/ethnology , Hyperpigmentation/therapy , Laser Therapy/methods , Lichen Planus/complications , Lichen Planus/ethnology , Lichen Planus/therapy , Nevus/complications , Nevus/ethnology , Nevus/therapy , Ochronosis/complications , Ochronosis/ethnology , Ochronosis/therapy , Skin Neoplasms/complications , Skin Neoplasms/ethnology , Skin Neoplasms/therapy
13.
Indian J Dermatol Venereol Leprol ; 77(5): 552-63; quiz 564, 2011.
Article in English | MEDLINE | ID: mdl-21860153

ABSTRACT

Facial melanoses (FM) are a common presentation in Indian patients, causing cosmetic disfigurement with considerable psychological impact. Some of the well defined causes of FM include melasma, Riehl's melanosis, Lichen planus pigmentosus, erythema dyschromicum perstans (EDP), erythrosis, and poikiloderma of Civatte. But there is considerable overlap in features amongst the clinical entities. Etiology in most of the causes is unknown, but some factors such as UV radiation in melasma, exposure to chemicals in EDP, exposure to allergens in Riehl's melanosis are implicated. Diagnosis is generally based on clinical features. The treatment of FM includes removal of aggravating factors, vigorous photoprotection, and some form of active pigment reduction either with topical agents or physical modes of treatment. Topical agents include hydroquinone (HQ), which is the most commonly used agent, often in combination with retinoic acid, corticosteroids, azelaic acid, kojic acid, and glycolic acid. Chemical peels are important modalities of physical therapy, other forms include lasers and dermabrasion.


Subject(s)
Facial Dermatoses/ethnology , Facial Dermatoses/pathology , Melanosis/ethnology , Melanosis/pathology , Administration, Topical , Animals , Facial Dermatoses/therapy , Humans , Hyperpigmentation/ethnology , Hyperpigmentation/pathology , Hyperpigmentation/therapy , Keratolytic Agents/administration & dosage , Melanosis/therapy , Tretinoin/administration & dosage , Ultraviolet Rays/adverse effects
14.
J Drugs Dermatol ; 10(5): 517-23, 2011 May.
Article in English | MEDLINE | ID: mdl-21533299

ABSTRACT

Melasma is an acquired skin condition characterized by irregular brown or hyperpigmented patches typically located on the forehead, cheeks, nose, chin and upper lip. The pathogenesis of melasma is not completely understood, but is thought to be influenced by genetics, UV exposure, thyroid dysfunction and hormonal influences from either pregnancy or hormonal therapeutic medications. Peoples of Latin descent comprise a vast array of skin colors and skin phototypes. Similarly, disorders of pigmentation, particularly melasma, occur more frequently in people of Latin descent when compared to the general population. Melasma can be particularly distressing to patients and has been shown to impact a patient's quality of life in several studies. These factors can raise significant quality of life issues and therefore treatment is not only significant for improving patient clinical outcomes, but is crucial in improving important psychological and emotional aspects of patients' overall well being. This article provides a stepwise approach to the treatment of melasma based on current literature recommendations.


Subject(s)
Hispanic or Latino , Melanosis/epidemiology , Skin Pigmentation , Facial Dermatoses/epidemiology , Facial Dermatoses/ethnology , Facial Dermatoses/therapy , Female , Humans , Melanosis/ethnology , Melanosis/therapy , Pregnancy , Quality of Life
15.
J Cosmet Dermatol ; 9(4): 302-6, 2010 Dec.
Article in English | MEDLINE | ID: mdl-21122049

ABSTRACT

Postinflammatory hyperpigmentation (PIH) developing after cosmetic procedures, such as chemical peeling and laser therapies, are always a concern, especially in Asians. Some cases of PIH tend to be spontaneously regressed; however, certain forms of PIH need to be treated with several therapeutic attempts, including bleaching creams, several kinds of Q-switched lasers, and erbium-doped fractional photothermolysis system, with various treatment outcomes. A 1064-nm Q-switched Nd:YAG laser with low-fluence therapy is easily applicable, and the therapeutic trial in our case was revealed to have minimal downtime without post-therapy bleeding or crust formation; the post-therapy erythema spontaneously resolved within a few hours. The 1064-nm Q-switched Nd:YAG laser with low-fluence treatment should be considered in the treatment of PIH caused by procedures like laser surgery and chemical peeling in Asian patients.


Subject(s)
Facial Dermatoses/radiotherapy , Hyperpigmentation/radiotherapy , Lasers, Solid-State/therapeutic use , Low-Level Light Therapy , Adult , Asian People , Face/pathology , Face/radiation effects , Facial Dermatoses/ethnology , Facial Dermatoses/etiology , Female , Humans , Hyperpigmentation/ethnology , Hyperpigmentation/etiology , Inflammation/complications , Male , Treatment Outcome
16.
Actas Dermosifiliogr ; 101(9): 749-57, 2010 Nov.
Article in Spanish | MEDLINE | ID: mdl-21034705

ABSTRACT

Pseudofolliculitis barbae is a chronic, irritating, and potentially disfiguring condition that develops as a result of attempts to eliminate hair from the beard area, usually by shaving. It is difficult to determine the incidence of the disorder, but some studies report that it affects up to 1 of every 5 caucasian individuals and that it is much more common in black persons. Clinically it is characterized by the appearance of inflammatory papules and pustules. Once pseudofolliculitis has become established, treatment consists of avoiding shaving and the use of medical treatment similar to that used in acne. However, the long-term result is much more dependent on prevention through a correct shaving technique. In severe cases or when a definitive solution is sought, the treatment of choice is photodepilation.


Subject(s)
Facial Dermatoses/etiology , Hair Diseases/etiology , Hair Removal/adverse effects , Benzoyl Peroxide/therapeutic use , Black People , Cicatrix/etiology , Cicatrix/prevention & control , Combined Modality Therapy , Dermatologic Agents/therapeutic use , Disease Susceptibility , Eflornithine/therapeutic use , Facial Dermatoses/drug therapy , Facial Dermatoses/ethnology , Facial Dermatoses/radiotherapy , Female , Folliculitis/drug therapy , Folliculitis/ethnology , Folliculitis/etiology , Folliculitis/radiotherapy , Hair Diseases/drug therapy , Hair Diseases/ethnology , Hair Diseases/radiotherapy , Hair Removal/instrumentation , Hair Removal/methods , Hirsutism/complications , Humans , Hyperpigmentation/etiology , Hyperpigmentation/prevention & control , Keloid/etiology , Keloid/prevention & control , Lasers, Dye/therapeutic use , Low-Level Light Therapy , Male , Skin Pigmentation , White People
17.
Clin Exp Dermatol ; 34(8): e521-30, 2009 Dec.
Article in English | MEDLINE | ID: mdl-19719761

ABSTRACT

BACKGROUND: People with sensitive skin vary not only in the signs and symptoms they experience, but also in the degree of sensitivity at different anatomical sites. AIM: To determine patterns of perceived sensitive skin using an epidemiological approach among a general population, evaluating the results for ethnic, gender and age differences. METHODS: Questionnaires designed to evaluate perceptions of sensitive skin in general and at specific body sites (face, body and genital area) were given to 1039 people. Respondents were not selected based on any criteria related to sensitive skin, but consisted of people participating in other studies on consumer products. RESULTS: Of the study population, 68.4% claimed their skin was sensitive to some degree, 77.3% claimed sensitive facial skin, 60.7% claimed sensitive body skin and 56.3% claimed sensitive skin in the genital area. There were no significant gender, ethnic or age differences, except in the genital area; a higher percentage of women and African Americans claimed sensitive skin in this area. CONCLUSIONS: The prevalence of perceived sensitive skin was higher in this study than in previous reports. Individuals had different perceptions about the degree of sensitivity at different anatomical sites.


Subject(s)
Dermatitis, Contact , Facial Dermatoses , Adolescent , Adult , Age Factors , Aged , Dermatitis, Contact/epidemiology , Dermatitis, Contact/ethnology , Epidemiologic Studies , Facial Dermatoses/epidemiology , Facial Dermatoses/ethnology , Female , Genital Diseases, Female/epidemiology , Genital Diseases, Female/ethnology , Genital Diseases, Male/epidemiology , Genital Diseases, Male/ethnology , Health Surveys , Humans , Male , Middle Aged , Prevalence , Sex Factors , Skin Irritancy Tests , Surveys and Questionnaires , United Kingdom/epidemiology , United States/epidemiology , Young Adult
18.
Semin Cutan Med Surg ; 28(2): 63-70, 2009 Jun.
Article in English | MEDLINE | ID: mdl-19608055

ABSTRACT

The demographics of the United States continue to evolve, with a growing proportion of the population consisting of non-Caucasian racial and ethnic groups. As darker skin types become more prevalent, so will the need to better understand their skin, the conditions that affect it, and optimal approaches for treatment. This population poses a special challenge for practitioners in part as a result of the sequelae often associated with the conditions in their own right - postinflammatory hyperpigmentation and scarring - and potential iatrogenic adverse effects that may occur during treatment. Through careful consideration of cultural, clinical, and therapeutic nuances, safe and effective management of common disorders in skin of color is achievable.


Subject(s)
Acne Vulgaris/ethnology , Black or African American , Skin Diseases/ethnology , Skin Diseases/therapy , Acne Keloid/ethnology , Acne Vulgaris/complications , Acne Vulgaris/therapy , Barbering , Facial Dermatoses/ethnology , Facial Dermatoses/therapy , Folliculitis/ethnology , Folliculitis/psychology , Foreign-Body Reaction/ethnology , Hair Removal , Humans , Hyperpigmentation/ethnology , Hyperpigmentation/therapy
19.
Ann Dermatol Venereol ; 135(10): 663-7, 2008 Oct.
Article in French | MEDLINE | ID: mdl-18929915

ABSTRACT

BACKGROUND: The term Facial Afro-Caribbean childhood eruption (FACE) was coined in 1990 to describe a perioral granulomatous eruption in black-skinned children. We present a typical case of this condition, together with a histological and immunohistochemical study. PATIENTS AND METHODS: A seven-year-old boy with black skin was referred for numerous nonpruritic papules that appeared on his face several months prior to the consultation. He had a past history of atopic dermatitis, but his mother denied any use of steroids or other topical treatment on his face. Examination showed numerous small lupoid and flesh-colored papules localised in the perioral, perinasal and periocular areas. Biopsy revealed a diffuse granulomatous infiltrate of the dermis comprising histiocytes, multinucleated giant cells and a heavy lymphocytic component. Histiocytes were CD68+ and CD1a-, while the majority of lymphocytes were CD3+ (70% CD8+ and 30% CD4+). DISCUSSION: This particular type of perioral dermatitis is seen chiefly in male children with black skin. Our histologic study revealed a diffuse and massive granulomatous infiltrate of the dermis, in contrast with the small size of the papules. Expression of CD68, absence of necrosis and dense CD3+ infiltrate in this disease resembles findings in the granulomatous variant of rosacea. This entity must be differentiated from lupus miliaris disseminatus faciei and from sarcoidosis.


Subject(s)
Facial Dermatoses/pathology , Granulomatous Disease, Chronic/pathology , Black People , Child , Facial Dermatoses/ethnology , Granulomatous Disease, Chronic/ethnology , Humans , Male
20.
Dermatol Online J ; 14(4): 10, 2008 Apr 15.
Article in English | MEDLINE | ID: mdl-18627732

ABSTRACT

Lichen nitidus is a relatively common inflammatory disorder of uncertain etiology seen primarily in the pediatric population. A rare variant may demonstrate a photodistribution of characteristic lesions. We describe 3 cases of lichen nitidus actinicus with prominent facial lesions.


Subject(s)
Black or African American , Face/pathology , Facial Dermatoses/pathology , Lichen Nitidus/pathology , Photosensitivity Disorders/pathology , Child , Facial Dermatoses/ethnology , Female , Humans , Lichen Nitidus/ethnology , Photosensitivity Disorders/ethnology , Skin/pathology , Sunlight/adverse effects
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