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1.
BMC Geriatr ; 22(1): 912, 2022 11 28.
Article in English | MEDLINE | ID: mdl-36443675

ABSTRACT

BACKGROUND: Femoral neck fracture and lacunar cerebral infarction (LCI) are the most common diseases in the elderly. When LCI patients undergo a series of traumas such as surgery, their postoperative recovery results are often poor. Moreover, few studies have explored the relationship between LCI and femoral neck fracture in the elderly. Therefore, this study will develop a ML (machine learning)-based model to predict LCI before surgery in elderly patients with a femoral neck fracture. METHODS: Professional medical staff retrospectively collected the data of 161 patients with unilateral femoral neck fracture who underwent surgery in the Second Affiliated Hospital of Wenzhou Medical University database from January 1, 2015, to January 1, 2020. Patients were divided into two groups based on LCI (diagnosis based on cranial CT image): the LCI group and the non-LCI group. Preoperative clinical characteristics and preoperative laboratory data were collected for all patients. Features were selected by univariate and multivariate logistic regression analysis, with age, white blood cell (WBC), prealbumin, aspartate aminotransferase (AST), total protein, globulin, serum creatinine (Scr), blood urea nitrogen (Bun)/Scr, lactate dehydrogenase (LDH), serum sodium and fibrinogen as the features of the ML model. Five machine learning algorithms, Logistic regression (LR), Gradient Boosting Machine (GBM), Extreme Gradient Boosting (XGBoost), Random Forest (RF), and Decision tree (DT), were used in combination with preoperative clinical characteristics and laboratory data to establish a predictive model of LCI in patients with a femoral neck fracture. Furthermore, indices like the area under the receiver operating characteristic (AUROC), sensitivity, specificity, and accuracy were calculated to test the models' performance. RESULTS: The AUROC of 5 ML models ranged from 0.76 to 0.95. It turned out that the RF model demonstrated the highest performance in predicting LCI for femoral neck fracture patients before surgery, whose AUROC was 0.95, sensitivity 1.00, specificity 0.81, and accuracy 0.90 in validation sets. Furthermore, the top 4 high-ranking variables in the RF model were prealbumin, fibrinogen, globulin and Scr, in descending order of importance. CONCLUSION: In this study, 5 ML models were developed and validated for patients with femoral neck fracture to predict preoperative LCI. RF model provides an excellent predictive value with an AUROC of 0.95. Clinicians can better conduct multidisciplinary perioperative management for patients with femoral neck fractures through this model and accelerate the postoperative recovery of patients.


Subject(s)
Femoral Neck Fractures , Prealbumin , Aged , Humans , Femoral Neck Fractures/diagnosis , Femoral Neck Fractures/surgery , Retrospective Studies , Machine Learning , Fibrinogen , Cerebral Infarction
2.
J Am Acad Orthop Surg ; 30(7): 302-311, 2022 Apr 01.
Article in English | MEDLINE | ID: mdl-35077440

ABSTRACT

Femoral neck stress fractures represent a relatively rare spectrum of injuries that most commonly affect military recruits and endurance athletes. If unrecognized and if proper treatment is not initiated, this condition carries potentially devastating consequences. Patients will typically present with an insidious onset, atraumatic hip, and groin pain that is relieved with rest. The condition may be initially misdiagnosed because radiographs are often normal. Magnetic resonance imaging has demonstrated superior specificity, sensitivity, and accuracy compared with other diagnostic modalities in identifying and classifying stress fractures of the femoral neck. Treatment algorithms are based on the MRI fracture morphology and presence of an intra-articular effusion. Nonsurgical management consists of a period of non-weight-bearing followed by gradual return to activity. Surgical management consists of prophylactic fracture fixation with cannulated screws to prevent fracture progression. If left untreated, patients may progress to a complete displaced femoral neck fracture, which can be associated with complications that include nonunion, osteonecrosis of the femoral head, and long-term disability. These poor outcomes emphasize the importance of early diagnosis and treatment of incomplete femoral neck stress fractures.


Subject(s)
Femoral Neck Fractures , Fractures, Stress , Femoral Neck Fractures/diagnosis , Femoral Neck Fractures/etiology , Femoral Neck Fractures/surgery , Femur Head , Femur Neck , Fracture Fixation/methods , Fracture Fixation, Internal/methods , Fractures, Stress/diagnosis , Fractures, Stress/etiology , Fractures, Stress/surgery , Humans
3.
J Korean Med Sci ; 36(38): e238, 2021 Oct 04.
Article in English | MEDLINE | ID: mdl-34609090

ABSTRACT

BACKGROUND: The aim of this study was to assess the prevalence of dementia as an underlying disease in elderly patients with hip fracture, to investigate the effect of dementia on postoperative mortality after surgery of hip fracture, and to analyze the differences in postoperative mortalities according to the severity of dementia through subgroup analysis. METHODS: This study selected 2,346 elderly patients who were diagnosed with unilateral intertrochanteric or femoral neck fractures who underwent surgery between January 2004 and December 2018. The patients were classified into the non-dementia group (2,196 patients) and dementia group (150 patients; no-medication [66 patients] and medication [84 patients] subgroups). The cumulative crude mortality rate was calculated, and 30-day, 60-day, 3-month, 6-month, and 1-year mortality rates were compared between the groups. A univariate regression test was performed using age, sex, diagnosis, surgery type, and Charlson's comorbidity index (CCI), as these variables had P values of < 0.10. Multivariate regression analysis was performed to identify independent risk factors associated with mortality. RESULTS: The 30-day, 60-day, 3-month, 6-month, and 1-year postoperative cumulative mortality rates were 1.8%, 3.8%, 5.6%, 8.9%, and 13.6%, respectively, in the non-dementia group, and 2%, 7.3%, 14%, 19.3%, and 24%, respectively, in the dementia group (P = 0.748, P = 0.048, P < 0.001, P < 0.001, and P = 0.001). The factors that affected the 1-year mortality were age (odds ratio [OR], 1.06; 95% confidence interval [CI], 1.02-1.08; P < 0.001), sex (OR, 2.68; 95% CI, 2.07-3.47; P < 0.001), CCI (OR, 1.34; 95% CI, 1.23-1.47; P < 0.001), and dementia (OR, 1.70; 95% CI, 1.46-1.08; P = 0.016). In subgroup analysis, severity of dementia influenced the 6-month mortality (OR, 1.41; 95% CI, 1.70-2.01; P = 0.018), and 1-year mortality (OR, 1.30; 95% CI, 1.17-1.90; P = 0.027). CONCLUSION: In elderly hip fracture patients, the comparison between patients with and without dementia revealed that dementia was an independent risk factor for mortality at a minimum of 1 year of follow-up, and the severity of dementia in hip fracture patients was a risk factor for mortality within 6 months and 1 year, postoperatively.


Subject(s)
Dementia/complications , Hip Fractures/mortality , Aged , Aged, 80 and over , Comorbidity , Dementia/drug therapy , Female , Femoral Neck Fractures/complications , Femoral Neck Fractures/diagnosis , Femoral Neck Fractures/mortality , Femoral Neck Fractures/surgery , Hip Fractures/complications , Hip Fractures/diagnosis , Hip Fractures/surgery , Humans , Male , Multivariate Analysis , Nootropic Agents/therapeutic use , Odds Ratio , Postoperative Period , Retrospective Studies , Risk Factors , Survival Rate
4.
BMC Musculoskelet Disord ; 22(1): 806, 2021 Sep 18.
Article in English | MEDLINE | ID: mdl-34537036

ABSTRACT

BACKGROUND: Performing postoperative laboratory tests following joint arthroplasty is a regular practice. However, the role of routine postoperative laboratory tests in primary hip arthroplasty is currently in doubt. This study aimed to assess the role of routine postoperative laboratory tests for femoral neck fractures in elderly patients who underwent hip hemiarthroplasty and to evaluate the risk factors for postoperative laboratory testing abnormalities and related interventions. METHODS: This retrospective study reviewed 735 consecutive patients with femoral neck fractures (FNFs) who underwent hip hemiarthroplasty at a single tertiary academic organization. Patient characteristic features and laboratory testing values were recorded. Logistic regression models were calculated to identify risk factors. RESULTS: A total of 321 elderly patients (> 75 years of age) were ultimately enrolled for analysis. Abnormal postoperative laboratory tests were found in 265 patients (82.6%). Only a minority of the included patients (7.5%) needed medical intervention to treat postoperative laboratory testing abnormalities. Multivariate logistic regression analysis reported that a higher Charlson comorbidity index (CCI) (P = 0.03), abnormal preoperative haemoglobin level (P < 0.01), higher intraoperative blood loss (P < 0.01) and less frequent tranexamic acid use (P = 0.05) were risk factors for abnormal postoperative laboratory tests. Furthermore, a higher CCI has been identified as a risk factor for patients needing clinical interventions related to laboratory abnormalities. CONCLUSIONS: Because 92.5% of laboratory tests did not influence postoperative management, the authors suggest that routine laboratory tests after hip hemiarthroplasty for FNFs are less instructive for the majority of elderly patients. Nevertheless, for patients with identified risk factors, postoperative laboratory tests are still required to identify the abnormalities that need to be managed.


Subject(s)
Arthroplasty, Replacement, Hip , Femoral Neck Fractures , Hemiarthroplasty , Aged , Arthroplasty, Replacement, Hip/adverse effects , Femoral Neck Fractures/diagnosis , Femoral Neck Fractures/epidemiology , Femoral Neck Fractures/surgery , Hemiarthroplasty/adverse effects , Humans , Postoperative Period , Retrospective Studies
5.
Eur J Med Res ; 26(1): 59, 2021 Jun 24.
Article in English | MEDLINE | ID: mdl-34167592

ABSTRACT

BACKGROUND: Femoral neck shortening can occur in young patients receiving internal fixation for Pauwels type II femoral neck fracture. The risk factors for neck shortening, which can affect hip function, are not clear. This study aimed to retrospectively identify risk factors for neck shortening after internal fixation with parallel partially threaded cannulated cancellous screws (FPTCS) for Pauwels type II femoral neck fracture in relatively young patients. METHODS: Clinical data from 122 cases with Pauwels type II femoral neck fracture from February 2014 to February 2019 were reviewed and analyzed, and causes of neck shortening were statistically analyzed. And the Chi-squared test or Fisher's exact test was used to compare indicators. Multivariate analysis was conducted with non-conditional logistic regression analysis. RESULTS: Statistically significant differences were found in age, sex, BMD, BMI, fracture type, posterior medial cortex comminution, and reduction quality between patients with femoral neck shortening and those without femoral neck shortening. Logistic regression analysis showed that fracture type, posterior medial cortex comminution, and reduction quality were the main risk factors for neck shortening. CONCLUSION: Fracture type, posterior medial cortex comminution, and reduction quality can be used as important reference indexes to predict the possibility of neck shortening after internal fixation with FPTCS for Pauwels type II femoral neck fracture in young patients. BMD and BMI may be also risk factors.


Subject(s)
Bone Screws , Femoral Neck Fractures/surgery , Fracture Fixation, Internal/adverse effects , Fracture Healing , Postoperative Complications/epidemiology , Adolescent , Adult , China/epidemiology , Female , Femoral Neck Fractures/diagnosis , Femoral Neck Fractures/physiopathology , Follow-Up Studies , Humans , Incidence , Male , Middle Aged , Retrospective Studies , Risk Factors , Young Adult
6.
Medicine (Baltimore) ; 100(17): e25708, 2021 Apr 30.
Article in English | MEDLINE | ID: mdl-33907153

ABSTRACT

ABSTRACT: The aim of this study was to evaluate the risk factors related to osteosynthesis failure in patients with concomitant ipsilateral femoral neck and shaft fractures, including old age; smoking habit; comminuted fragments; infra-isthmus fracture; angular malreduction; unsatisfactory reduction (fracture gap >5 mm); and treatment with single construct.Patients over the age of 20 with concomitant ipsilateral femoral neck and shaft fractures diagnosed at a level one medical center between 2003 and 2019 were included. Treatment modalities included single construct with/without an antirotational screw for the neck and dual constructs. Radiographic outcomes were assessed from anteroposterior and lateral hip radiographs at follow-up. Fisher exact test was used to analyze categorical variables. The presence of avascular necrosis of the femoral head, delayed union, atrophic or hypertrophic nonunion of the femoral shaft fracture, and loss of reduction were identified as factors related to treatment failure.A total of 22 patients were included in this study. The average age was 58.5 years, and the majority was male (68.2%). The minimum radiographic follow-up duration was 12 months, and the median follow-up time was 12 (interquartile range 12-24) months.Femoral neck osteosynthesis failed in 3 patients, whereas femoral shaft osteosynthesis failed in 12 patients. Fisher exact test demonstrated the failure of femoral shaft osteosynthesis was significantly more frequent in the single-construct cohort in 16 infra-isthmus femoral fracture cases (P = .034).In ipsilateral femoral neck and infra-isthmus shaft fractures, it is better to treat the neck and shaft fractures with separate implants (dual constructs).In a dual-construct cohort, separate plate fixation of the femoral shaft achieved a better result in terms of bone union than retrograde nailing of the shaft (bone union rate: 4/8 vs 0/2).


Subject(s)
Femoral Fractures , Femoral Neck Fractures , Fracture Fixation, Intramedullary , Internal Fixators , Postoperative Complications , Aftercare/methods , Female , Femoral Fractures/diagnosis , Femoral Fractures/epidemiology , Femoral Fractures/surgery , Femoral Neck Fractures/diagnosis , Femoral Neck Fractures/epidemiology , Femoral Neck Fractures/surgery , Fracture Fixation, Intramedullary/adverse effects , Fracture Fixation, Intramedullary/instrumentation , Fracture Fixation, Intramedullary/methods , Fractures, Comminuted/diagnosis , Fractures, Comminuted/epidemiology , Fractures, Comminuted/surgery , Humans , Internal Fixators/standards , Internal Fixators/statistics & numerical data , Male , Middle Aged , Postoperative Complications/diagnosis , Postoperative Complications/epidemiology , Radiography/methods , Retrospective Studies , Risk Assessment/methods , Risk Assessment/statistics & numerical data , Risk Factors , Taiwan/epidemiology , Treatment Failure
7.
J Bone Joint Surg Am ; 103(15): 1431-1437, 2021 08 04.
Article in English | MEDLINE | ID: mdl-33830965

ABSTRACT

BACKGROUND: The purpose of the present study was to investigate the effectiveness of using the computed tomography (CT) capsular sign with lipohemarthrosis of the hip joint as a selective indicator for preoperative magnetic resonance imaging (MRI) of the hip or prophylactic fixation of the ipsilateral femoral neck for the prevention of unplanned surgery due to delayed diagnosis of occult ipsilateral femoral neck fractures in patients with high-energy femoral shaft fractures. METHODS: We evaluated the CT capsular sign with lipohemarthrosis in patients with a high-energy femoral shaft fracture without a preoperative diagnosis of an ipsilateral femoral neck fracture. The CT capsular sign with lipohemarthrosis was considered positive when the side-to-side difference in anterior capsular distension was >1 mm and lipohemarthrosis was seen on soft-tissue-window CT images. A positive CT capsular sign with lipohemarthrosis prompts preoperative hip MRI or prophylactic femoral neck fixation with a reconstruction nail. RESULTS: One hundred and fifty-six consecutive patients were included. Eight patients were preoperatively diagnosed with a displaced or hairline ipsilateral femoral neck fracture, whereas the remaining 148 patients showed no ipsilateral femoral neck fracture on radiographs and bone-window CT images. On soft-tissue-window CT images, 29 (19.6%) of the 148 patients had a positive CT capsular sign with lipohemarthrosis. We performed preoperative MRI for 3 patients; in the remaining 26 patients, prophylactic femoral neck fixation was performed with a reconstruction nail. We identified 5 occult ipsilateral femoral neck fractures among the 29 patients with a positive sign: 2 on preoperative MRI scans, 2 on immediate postoperative radiographs, and 1 on radiographs made 6 weeks postoperatively. In 119 patients with a negative sign, no occult ipsilateral femoral neck fracture was identified. All occult ipsilateral femoral neck fractures healed without further displacement of the femoral neck. Consequently, additional unplanned surgery for delayed diagnosis of occult ipsilateral femoral neck fracture was not required. CONCLUSIONS: The use of the CT capsular sign with lipohemarthrosis as a selective indicator for preoperative hip MRI or prophylactic femoral neck fixation with a reconstruction nail in patients with high-energy femoral shaft fractures is effective for preventing unplanned surgery due to delayed diagnosis of occult ipsilateral femoral neck fractures. LEVEL OF EVIDENCE: Diagnostic Level I. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Delayed Diagnosis/prevention & control , Femoral Fractures/surgery , Femoral Neck Fractures/diagnosis , Hemarthrosis/diagnosis , Hip Joint/diagnostic imaging , Adolescent , Adult , Aged , Female , Femoral Fractures/complications , Femoral Neck Fractures/complications , Femoral Neck Fractures/surgery , Fracture Fixation, Intramedullary , Hemarthrosis/etiology , Hip Joint/surgery , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Preoperative Period , Retrospective Studies , Tomography, X-Ray Computed , Young Adult
8.
J Orthop Surg (Hong Kong) ; 29(1): 23094990211003344, 2021.
Article in English | MEDLINE | ID: mdl-33779387

ABSTRACT

PURPOSE: This study aims to systematically review the literature comparing surgical treatments options and respective failure rates for basicervical hip fractures. METHODS: A comprehensive search of databases, including MEDLINE, Embase, Web of Science, and Cochrane Central for studies published in English on or before June 21, 2019 was performed. Selected search terms included "basicervical," "basi cervical," "AO/OTA type 31-B," "femoral neck fracture" AND "bone nails," "bone screws," "fracture fixation," "internal fixation," "arthroplasty," "cephalomedullary," "sliding hip screw," "ORIF," and "treatment outcome." We included studies that assessed outcomes of basicervical fracture fixation using open reduction internal fixation or arthroplasty. Two authors extracted the following data from each paper: study design, country, cohort year, definition of basicervical, intervention type, sample size, patient demographics, follow-up length, percent of fractures that required revision, and the percent of implants that failed. RESULTS: Sixteen articles encompassing 910 patients were included. The main outcome was the percent of implants that required revision. The total revision rates were 8% (8 studies, 157 patients, range 0%-55%) for cephalomedullary nails, 7% (10 studies, 584 patients, range 0%-18%) for sliding hip screws, 23% (3 studies, 40 patients, range 16%-50%) for cannulated screws, 0% (1 study, 6 patients) for total hip arthroplasty, and 8% (2 studies, 13 patients, range 0%-11%) for hemiarthroplasty. CONCLUSION: Management of basicervical fractures with SHS and CMN produces similar failure and re-operation rates. Limited evidence is available on the use of cannulated screws and arthroplasty, but available studies suggest that cannulated screws have an unacceptable revision rate (23%) while arthroplasty may be acceptable. Future studies examining the comparative efficacy of various fixation methods would benefit from strict definition of fracture type as well as consistent reporting of functional outcomes, re-operation rates, and mortality.


Subject(s)
Femoral Neck Fractures/diagnosis , Femoral Neck Fractures/surgery , Hip Fractures/diagnosis , Hip Fractures/surgery , Aged , Aged, 80 and over , Bone Nails/adverse effects , Bone Nails/statistics & numerical data , Bone Screws/adverse effects , Bone Screws/statistics & numerical data , Female , Femoral Neck Fractures/epidemiology , Fracture Fixation, Internal/adverse effects , Fracture Fixation, Internal/methods , Fracture Fixation, Internal/statistics & numerical data , Hip Fractures/epidemiology , Humans , Male , Open Fracture Reduction/adverse effects , Open Fracture Reduction/methods , Open Fracture Reduction/statistics & numerical data , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Prognosis , Reoperation/methods , Reoperation/statistics & numerical data , Treatment Outcome
9.
JBJS Case Connect ; 10(3): e20.00288, 2020.
Article in English | MEDLINE | ID: mdl-32910604

ABSTRACT

CASE: Coronavirus disease 2019 (COVID-19) is a pandemic respiratory disease. Patients typically present with fever, cough, and radiological lung changes. However, a significant proportion of these patients are asymptomatic. To date, we have limited information on the operations performed on these patients. We report our experience of a relatively asymptomatic elderly patient who underwent surgery for a hip fracture and was confirmed postoperatively to have COVID-19. CONCLUSION: Meticulous hand hygiene and use of surgical mask in daily practice is crucial to protect against asymptomatic and undiagnosed patients.


Subject(s)
Asymptomatic Diseases , Betacoronavirus/isolation & purification , Coronavirus Infections , Delayed Diagnosis/prevention & control , Femoral Neck Fractures/diagnosis , Hemiarthroplasty/methods , Infection Control , Pandemics , Pneumonia, Viral , Aged, 80 and over , COVID-19 , Coronavirus Infections/diagnosis , Coronavirus Infections/physiopathology , Female , Humans , Infection Control/methods , Infection Control/standards , Pneumonia, Viral/diagnosis , Pneumonia, Viral/physiopathology , Postoperative Period , SARS-CoV-2 , Treatment Outcome , Universal Precautions/methods
10.
Acta Orthop ; 91(6): 699-704, 2020 12.
Article in English | MEDLINE | ID: mdl-32783544

ABSTRACT

Background and purpose - Deep-learning approaches based on convolutional neural networks (CNNs) are gaining interest in the medical imaging field. We evaluated the diagnostic performance of a CNN to discriminate femoral neck fractures, trochanteric fractures, and non-fracture using antero-posterior (AP) and lateral hip radiographs. Patients and methods - 1,703 plain hip AP radiographs and 1,220 plain hip lateral radiographs were included in the total dataset. 150 images each of the AP and lateral views were separated out and the remainder of the dataset was used for training. The CNN made the diagnosis based on: (1) AP radiographs alone, (2) lateral radiographs alone, or (3) both AP and lateral radiographs combined. The diagnostic performance of the CNN was measured by the accuracy, recall, precision, and F1 score. We further compared the CNN's performance with that of orthopedic surgeons. Results - The average accuracy, recall, precision, and F1 score of the CNN based on both anteroposterior and lateral radiographs were 0.98, 0.98, 0.98, and 0.98, respectively. The accuracy of the CNN was comparable to, or statistically significantly better than, that of the orthopedic surgeons regardless of radiographic view used. In the CNN model, the accuracy of the diagnosis based on both views was significantly better than the lateral view alone and tended to be better than the AP view alone. Interpretation - The CNN exhibited comparable or superior performance to that of orthopedic surgeons to discriminate femoral neck fractures, trochanteric fractures, and non-fracture using both AP and lateral hip radiographs.


Subject(s)
Diagnosis, Computer-Assisted/methods , Femoral Neck Fractures/diagnosis , Femur/diagnostic imaging , Hip Fractures/diagnosis , Neural Networks, Computer , Radiography/methods , Aged, 80 and over , Deep Learning , Diagnosis, Differential , Female , Humans , Male , Medical Records, Problem-Oriented , Orthopedic Surgeons , Outcome Assessment, Health Care , Sensitivity and Specificity
11.
BMC Musculoskelet Disord ; 21(1): 242, 2020 Apr 15.
Article in English | MEDLINE | ID: mdl-32293406

ABSTRACT

BACKGROUND: Simultaneous bilateral femoral neck fractures are extremely rare without obvious injury. Herein, we report the case of a patient on dialysis presenting with bilateral femoral neck fractures, which is a condition with high complication and mortality rates according to a review of the pertinent literature. CASE PRESENTATION: We report the case a 47-year-old female with a history of 8 years of haemodialysis due to polycystic kidney disease who presented with bilateral hip pain during walking. The clinical history and results of physical and radiographic examinations of this patient are shown. Single-stage bilateral hemiarthroplasty was performed after a multidisciplinary team consultation. Three days after the operation, she could ambulate with a walker. The woman gradually regained her previous ability to walk over 6 months after surgery. CONCLUSIONS: A multidisciplinary team consultation for perioperative management is necessary and effective in patients on dialysis. Early diagnosis with prompt surgical treatment could lead to favourable recovery.


Subject(s)
Femoral Neck Fractures/etiology , Femoral Neck Fractures/surgery , Polycystic Kidney Diseases/complications , Renal Dialysis , Female , Femoral Neck Fractures/diagnosis , Fracture Fixation, Internal/methods , Hemiarthroplasty/methods , Humans , Middle Aged , Polycystic Kidney Diseases/therapy , Treatment Outcome
13.
Zhongguo Gu Shang ; 33(1): 43-6, 2020 Jan 25.
Article in Chinese | MEDLINE | ID: mdl-32115923

ABSTRACT

OBJECTIVE: To compare the relationship between direct lateral approach and posterolateral approach in the treatment of femoral neck fracture, and to provide reference for the choice of the best approach. METHODS: From January 2015 to December 2018, 266 patients with femoral neck fracture underwent hip replacement were selected, including 154 males and 112 females, aged 58 to 74 (69.8±8.1) years. Direct lateral approach and posterolateral approach were used in 133 cases in each group. The difference of reoperation rate and dislocation rate between the two groups was compared. Cox proportional risk regression model was used to evaluate the potential factors of reoperation and dislocation after total hip replacement. RESULTS: The rate of reoperation and dislocation in direct lateral approach group was lower than that in posterolateral approach group (P<0.05) . Cox proportional risk regression model showed that posterolateral approach had higher postoperative reoperation rate and dislocation rate than direct lateral approach, and its relative risk ratio (95%CI) was, reoperationï¼»2.65 (1.23- 5.36) , P=0.02ï¼½; dislocationï¼»5.15 (1.68-9.15) , P=0.01ï¼½. CONCLUSION: Posterolateral approach is the influencing factor of reoperation and dislocation after hip replacement. Age, gender, cognitive dysfunction, replacement position, ASA score and other factors have no effect on reoperation and dislocation.


Subject(s)
Arthroplasty, Replacement, Hip , Femoral Neck Fractures , Joint Dislocations , Aged , Female , Femoral Neck Fractures/complications , Femoral Neck Fractures/diagnosis , Femoral Neck Fractures/surgery , Humans , Joint Dislocations/complications , Joint Dislocations/diagnosis , Joint Dislocations/surgery , Male , Middle Aged , Reoperation , Treatment Outcome
14.
BMC Musculoskelet Disord ; 21(1): 139, 2020 Mar 03.
Article in English | MEDLINE | ID: mdl-32126995

ABSTRACT

BACKGROUND: The Dynamic Locking Blade Plate (DLBP) was recently introduced for fixation of displaced femoral neck fractures (FNF) and has been well received. Although the results of this implant in young patients are promising, the DLBP has not yet been compared to a standard device such as the Dynamic Hip Screw (DHS). The aim of this study is to compare the clinical outcome and costs of displaced FNF treated with internal fixation by means of either the DLBP or the DHS in patients up to 65 years of age. We hypothesize that the DLBP is superior compared to the DHS in terms of revision surgery rate, union rate, incidence of avascular necrosis and implant related failure. METHODS: The DEFENDD (DisplacEd Femoral Neck fractures Dlbp versus Dhs) trial is a multicentre randomized controlled trial that will include 266 patients of 18-65 years with a displaced FNF. Patients will be randomized to receive either a DLBP or a DHS with a 1:1 allocation using a random block size, stratified for centre. Clinical follow up will last 1 year and questionnaires will be obtained up to 2 years. The main outcome parameter is the incidence of revision surgery within 1 year, due to either non-union, avascular necrosis (AVN) or cut out of the implant. Secondary study parameters are the incidence of avascular necrosis, non-union, (implant related) complications, functional outcome, elective removal of the implant and health-related quality of life and costs. DISCUSSION: The outcome of the DEFENDD trial will provide high-level evidence of which implant is favourable for the treatment of femoral neck fractures in young patients (≤65 years). TRIAL REGISTRATION: Netherlands Trial Register, NL7300 Registration date 25-09-2018.


Subject(s)
Bone Plates , Bone Screws , Femoral Neck Fractures/surgery , Fracture Fixation, Internal/methods , Hip Joint/surgery , Adolescent , Adult , Aged , Female , Femoral Neck Fractures/diagnosis , Fracture Fixation, Internal/instrumentation , Humans , Male , Middle Aged , Young Adult
15.
Acta Orthop Belg ; 86(2): 233-238, 2020 Jun.
Article in English | MEDLINE | ID: mdl-33418612

ABSTRACT

The aim of this study is to assess if there is a difference in outcomes between a dynamic hip screw with or without an anti-rotation screw in the treatment of hip fractures. All patients with an intracapsular hip fracture who underwent dynamic hip screw osteosynthesis between January 2010 and December 2013 in three Dutch hospitals were reviewed. Minimal follow-up was one year. The study included a total of 364 patients. 24 patients were lost to follow-up and excluded. 297 (87.4%) were in the dynamic hip screw group and 43 (12.6%) in the dynamic hip with anti-rotation screw group. Direct comparison of patient characteristics of the two groups showed significant differences in age, sex, Garden classification and Pauwels classification. Patients operated with a dynamic hip screw and anti-rotation screw are significantly younger and their fractures are significantly more dislocated and steeper. To draw conclusions about differences in outcome, a randomised clinical trial should be performed.


Subject(s)
Bone Screws , Femoral Neck Fractures/surgery , Fracture Dislocation , Fracture Fixation, Internal , Postoperative Complications , Age Factors , Bone Screws/adverse effects , Bone Screws/classification , Bone Screws/statistics & numerical data , Equipment Design , Female , Femoral Neck Fractures/diagnosis , Femoral Neck Fractures/epidemiology , Fracture Dislocation/diagnosis , Fracture Dislocation/epidemiology , Fracture Dislocation/genetics , Fracture Dislocation/prevention & control , Fracture Fixation, Internal/adverse effects , Fracture Fixation, Internal/instrumentation , Fracture Fixation, Internal/methods , Fracture Healing , Humans , Male , Middle Aged , Needs Assessment , Netherlands/epidemiology , Postoperative Complications/diagnosis , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Postoperative Complications/prevention & control , Risk Adjustment/methods , Risk Factors , Torsion, Mechanical
16.
J Invest Surg ; 33(5): 428-437, 2020 Jun.
Article in English | MEDLINE | ID: mdl-30516078

ABSTRACT

Background: Little is known about how biomechanics govern the five fixtures such as DHS, MLS, DHS + LS, LP, and HA are accepted as common therapeutic techniques. Aims and objectives: A series of numerical models for a femoral neck fracture of Pauwels-I will be constructed by innovative approach of finite element in order to determine the most optimized option in comparison with biomechanical performance. Method: Twenty sets of computer tomography scanned femora were imported onto Mimics to extract 3 D models; these specimens were transferred to Geomagic-Studio for a simulative osteotomy and kyrtograph; then, they underwent UG to fit simulative solid models; 5 sorts of fixture were then expressed by Pro-Engineer virtually. After processing with HyperMesh, all compartments (fracture model + internal implant) were assembled onto 5 systems: "Dynamic Hip Screw (DHS), Multiple Lag screw (MLS), DHS + LS, femoral Locking Plate (LP) and HemiArthroplasty (HA)." Eventually, numerical models of the finite-elemental analysis were exported to AnSys to determine the solution. Result: Four models of fixation and a simulation of HA for Pauwels-I were established, validated, and analyzed with the following findings: In term of displacement, these 5 fixtures ranged between 0.3801 and 0.7536 mm have no significant difference; in term of stress, the averages of peaks for integral assemblage are b(MLS) = 43.5766 ≈< d(LP) = 43.6657 ≈< e(Ha) = 43.6657 < c(DHS + LS) = 66.5494 < a(DHS) = 105.617 in MPa indicate that MLS, LP and HA are not significantly different, but less than DHS + LS or DHS in each. Conclusion: A fixture of MLS or LP with optional HA should be recommended to clinically optimize a Pauwels-I facture.


Subject(s)
Femoral Neck Fractures/surgery , Fracture Fixation, Internal/methods , Hemiarthroplasty/methods , Models, Biological , Osteotomy/methods , Adult , Biomechanical Phenomena , Bone Plates , Bone Screws , Elastic Modulus , Femoral Neck Fractures/classification , Femoral Neck Fractures/diagnosis , Femur/diagnostic imaging , Femur/injuries , Femur/surgery , Finite Element Analysis , Fracture Fixation, Internal/instrumentation , Hemiarthroplasty/instrumentation , Hip Prosthesis , Humans , Imaging, Three-Dimensional , Materials Testing , Osteotomy/instrumentation , Prosthesis Design , Tomography, X-Ray Computed
17.
J Orthop Surg (Hong Kong) ; 28(1): 2309499019889682, 2020.
Article in English | MEDLINE | ID: mdl-31833450

ABSTRACT

OBJECTIVE: This study evaluated the efficacy of surgery for femoral neck fractures in children after a 24-h delay and the factors affecting the risk of complications. METHODS: The study included 16 children who underwent surgery after the first 24 h for femoral neck fractures. According to Delbet's classification, there were 2 type I, 11 type II, and 3 (four hips) type III cases. The mean time from injury to surgery was 85 h (range 27-240 h). According to Garden's classification, there were 1 type II, 14 type III, and 1 type IV (two hips) cases. Initial surgery consisted of closed reduction and hematocele drainage with a 20-mL needle tube. If the procedure failed, open reduction was performed. Internal fixation (K-wire pinning, screw) was performed after closed (n = 9) or open (n = 8) reduction. The results were assessed using the Ratliff criteria after a mean follow-up of 23.2 months. Patient age, type of fracture, complications, treatment, and avascular necrosis (AVN) were evaluated. RESULTS: The results were good in 15 hips (88.2%) and fair in 2 hips (11.8%, one type II case with closed reduction and one type I case with open reduction). The most frequent complication was AVN (4 of 17; 23.5%; three Ratliff good and one fair), which was significantly related to poor outcomes. AVN occurred in one hip in the closed reduction group (Delbet's type II, 12.5%) and in three in the open reduction group (one Delbet's type I, 50%; two Delbet's type II, 66.7%). There were no significant differences in the time from injury to operation (27, 54, 64, and 116 h) and AVN incidence or Ratliff criteria. CONCLUSIONS: The efficacy of delayed reduction fixation of the femoral neck was better in the closed reduction group than in the open reduction group. Fracture location closer to the femoral head and older age affected the incidence of AVN.


Subject(s)
Femoral Neck Fractures/surgery , Femur Head Necrosis/etiology , Fracture Fixation, Internal/adverse effects , Open Fracture Reduction/adverse effects , Plastic Surgery Procedures/adverse effects , Postoperative Complications/epidemiology , Bone Screws , Bone Wires , Child , Child, Preschool , China/epidemiology , Female , Femoral Neck Fractures/diagnosis , Femur Head Necrosis/diagnosis , Femur Head Necrosis/epidemiology , Fracture Fixation, Internal/methods , Humans , Incidence , Infant , Male , Retrospective Studies , Treatment Outcome
18.
J Arthroplasty ; 35(4): 1023-1028, 2020 04.
Article in English | MEDLINE | ID: mdl-31859012

ABSTRACT

BACKGROUND: Current evidence suggests that cognitive capacities in patients who sustain a femoral neck fracture (FNF) correlate to patient outcome. We hypothesized that a simple selection procedure with 2 questions: "Can you perform your groceries independently?" and "Can you prepare your daily medications unassisted?", which imply a certain level of physical and cognitive function, could identify patients with early cognitive impairment and as a result influence the outcome of hip arthroplasty following an FNF. METHODS: At our clinic, the selection procedure was introduced in 2012 to simplify decision-making in geriatric FNF. At the time of surgery, patients received a total hip arthroplasty (THA) when able to perform their grocery shopping and prepare their daily medications unassisted (n = 100); otherwise, a hemiarthroplasty (HA) was performed (n = 100). Postoperative complications and mortality were assessed retrospectively. Second, we prospectively investigated whether patients' inability to perform groceries or prepare medications was associated with the presence of early cognitive impairment, tested with the Consortium to Establish a Registry for Alzheimer's Disease-Neuropsychological Assessment Battery. RESULTS: The screening questions showed almost perfect agreement (k = 0.8; sensitivity/specificity: 82%/95%) to early cognitive impairment. The 30-day mortality for THA and HA patients was 2% and 4%, respectively. The 1-year and 5-year survivorship for the THA group was 95% and 87% and for the HA group 63% and 8%, respectively. Complication rates were comparable. CONCLUSION: The results might suggest that 2 simple screening questions could help in the decision-making of the appropriate surgical treatment in elderly patients suffering from a displaced FNF.


Subject(s)
Arthroplasty, Replacement, Hip , Cognitive Dysfunction , Femoral Neck Fractures , Hemiarthroplasty , Aged , Arthroplasty, Replacement, Hip/adverse effects , Cognitive Dysfunction/diagnosis , Cognitive Dysfunction/epidemiology , Cognitive Dysfunction/etiology , Femoral Neck Fractures/diagnosis , Femoral Neck Fractures/surgery , Hemiarthroplasty/adverse effects , Humans , Retrospective Studies
20.
J Orthop Surg (Hong Kong) ; 27(3): 2309499019877530, 2019.
Article in English | MEDLINE | ID: mdl-31578134

ABSTRACT

BACKGROUND: Hydroxyapatite (HA)-coated stem has been introduced to decrease complications and eventually achieve quicker implant ingrowth and long-term stability. The aim of this study was to determine subsidence rate and incidence of perioperative periprosthetic fracture (PPF) of uncemented collarless Corail stem for displaced femoral neck fractures according to Dorr type. METHODS: A retrospective review of plain radiographs and clinical data was carried out to identify consecutive patients who underwent uncemented hip hemiarthroplasty using collarless HA-coated Corail stem between March 2010 and August 2014. The risk of subsidence and PPF according to Dorr type was evaluated. RESULTS: Dorr types A, B, and C were found in 66 (median age 74, 29.7%), 107 (median age 77, 48.2%), and 49 (median age 80, 22.1%) cases, respectively. Subsidence of stem occurred in eight (3.6%) cases. Dorr type had significant relationship (p < 0.05) with subsidence. Type C canals had higher rates of subsidence. PPFs occurred in 11 (5.0%) cases without showing significant difference among Dorr types not significant (n.s.). Female gender was not influential on subsidence (n.s.) and PPF (n.s.). CONCLUSION: Dorr type C had higher risk of subsidence when using uncemented collarless HA-coated stem. Dorr canal type had no bearing on risk of PPFs. Women did not have significantly higher risk of both subsidence and PPFs compared to men. A collarless fully HA-coated Corail stem had 3.6% of radiological subsidence and 5.0% of PPF risk.


Subject(s)
Arthroplasty, Replacement, Hip/adverse effects , Coated Materials, Biocompatible , Durapatite , Femoral Neck Fractures/surgery , Hip Prosthesis/adverse effects , Periprosthetic Fractures/surgery , Aged , Aged, 80 and over , Female , Femoral Neck Fractures/diagnosis , Humans , Incidence , Male , Periprosthetic Fractures/diagnosis , Periprosthetic Fractures/epidemiology , Radiography , Reoperation , Retrospective Studies , Risk Factors
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