1.
Bulletin of the Pan American Health Organization (PAHO)
; 15(1): 58-64, 1981.
Article
in English
| PAHO
| ID: pah-5729
2.
In. Ferreira Lopes, C. Recent developments in the therapy of chromoblastomycosis / Proceedings of the Fifth International Conference on the Mycoses: Superficial, cutaneous, and subcutaneous infections. Washington, D.C, Pan American Health Organization, 1978. p.344-9. (PAHO. Scientific Publication, 396).
Monography
in English
| PAHO
| ID: pah-12766
ABSTRACT
FLUCYTOSINE (5-FLUOROCYTOSINE, OR 5-FC) IS A FLUORINATED PYRIMIDINE THAT ACTIVELY COMBATS THE FOLLOWING FUNGI: CANDIDA ALBICANS, CRYPTOCOCCUS NEOFORMANS, AND THE AGENTS CAUSINGCHROMOBLASTOMYCOSIS. THE WAY IT ACTS ON THESE FUNGI IS NOT YET CLEARLY UNDERSTOOD. CONTACT WITH THE FUNGUS PRODUCES DEAMINATION OF THE DRUG, AND ITS DEAMINATED FORM KNOWN AS 5FLUOROURACILAPPARENTLY INHIBITS PROTEIN SYNTHESIS IN THE PARASITE
