Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 260
Filter
1.
Multimedia | Multimedia Resources | ID: multimedia-9687

ABSTRACT

Saúde promove conscientização sobre o consumo de açúcar em webinário No dia 21/01 o evento que integra o ciclo de encontros virtuais debaterá as ações para abordar e reverter o consumo excessivo de açúcar Estudos mostram que o consumo excessivo de açúcar está relacionado ao ganho de peso, à obesidade, ao diabetes tipo 2, às doenças cardiovasculares e à cárie dentária. No Brasil, segundo a Pesquisa de Orçamentos Familiares (POF 2017-2018), 85,4% da população adiciona açúcar em alimentos e bebida.


Subject(s)
Food Guide , Sugars/adverse effects , Diet, Healthy , Food, Formulated/statistics & numerical data , Sugar-Sweetened Beverages/statistics & numerical data , Feeding Behavior , 51402 , Food-Processing Industry/economics , Pan American Health Organization , Health Promotion , Food Publicity , Child Nutrition , Food Security , Brazil
2.
J Nutr ; 151(Suppl 1): 29S-37S, 2021 02 15.
Article in English | MEDLINE | ID: mdl-33582782

ABSTRACT

The double fortification of salt with iodine and iron has been proposed as a method for the mass prevention of iron deficiency anemia. This article reports on the technical and financial aspects of the production of such double fortified salt (DFS) based on the experiences of current and past producers. It draws contrasts with the established process of fortifying salt solely with iodine particularly examining the cost and complexity of the processes involved. Based on these factors it questions the commercial viability of existing DFS formulations and thus their sustainability as vehicles for the widespread distribution of iron outside a subsidized environment. It makes suggestions for the future development of DFS particularly relating to the development of less expensive iron formulations suitable for use with lower quality salts and identifies key technical and economic areas to be taken into account when considering the production of DFS.


Subject(s)
Food Technology/economics , Food Technology/standards , Food, Fortified , Iodine , Iron, Dietary/administration & dosage , Sodium Chloride, Dietary , Food-Processing Industry/economics , Food-Processing Industry/standards , Humans , India , Internationality , Iron, Dietary/classification
3.
Molecules ; 26(2)2021 Jan 19.
Article in English | MEDLINE | ID: mdl-33478152

ABSTRACT

The food sector includes several large industries such as canned food, pasta, flour, frozen products, and beverages. Those industries transform agricultural raw materials into added-value products. The fruit and vegetable industry is the largest and fastest-growing segment of the world agricultural production market, which commercialize various products such as juices, jams, and dehydrated products, followed by the cereal industry products such as chocolate, beer, and vegetable oils are produced. Similarly, the root and tuber industry produces flours and starches essential for the daily diet due to their high carbohydrate content. However, the processing of these foods generates a large amount of waste several times improperly disposed of in landfills. Due to the increase in the world's population, the indiscriminate use of natural resources generates waste and food supply limitations due to the scarcity of resources, increasing hunger worldwide. The circular economy offers various tools for raising awareness for the recovery of waste, one of the best alternatives to mitigate the excessive consumption of raw materials and reduce waste. The loss and waste of food as a raw material offers bioactive compounds, enzymes, and nutrients that add value to the food cosmetic and pharmaceutical industries. This paper systematically reviewed literature with different food loss and waste by-products as animal feed, cosmetic, and pharmaceutical products that strongly contribute to the paradigm shift to a circular economy. Additionally, this review compiles studies related to the integral recovery of by-products from the processing of fruits, vegetables, tubers, cereals, and legumes from the food industry, with the potential in SARS-CoV-2 disease and bacterial diseases treatment.


Subject(s)
Agriculture/methods , Drug Industry , Food Industry , Waste Products/economics , Agriculture/economics , Cosmetics/economics , Edible Grain , Food-Processing Industry/economics , Food-Processing Industry/methods , Fruit , Plant Roots , Plant Tubers , Vegetables
4.
PLoS One ; 15(8): e0237456, 2020.
Article in English | MEDLINE | ID: mdl-32790790

ABSTRACT

In the transformation of agri-food systems in developing countries, we usually see rapid changes in the dairy sector. However, good data for understanding patterns and inclusiveness of this transformation are often lacking. This is important given implications for policy design and service and technology provision towards better performing dairy sectors in these settings. Relying on a combination of unique diverse large-scale datasets and methods, we analyze transformation patterns in the dairy value chain supplying Addis Ababa, the capital of Ethiopia, the second most populous country in Africa. Over the last decade, we note a rapid increase in expenditures on dairy products by urban consumers, especially among the better-off. Relatedly, the number of dairy processing firms in Ethiopia tripled over the same period, supplying a significant part of these dairy products, especially pasteurized milk, to the city's residents. Upstream at the production level, we find improved access to livestock services, higher adoption of cross-bred cows, an increase in milk yields, expanding liquid milk markets, a sizable urban farm sector supplying almost one-third of all liquid milk consumed in the city, and an upscaling process with larger commercial dairy farms becoming more prevalent. However, average milk yields are still low and not all dairy farmers are included in this transformation process. Small farms with dairy animals as well as those in more remote areas benefit less from access to services and adopt less these modern practices. For these more disadvantaged farmers, stagnation in milk yields and even declines-depending on the data source used-are observed.


Subject(s)
Dairying/statistics & numerical data , Animals , Cattle , Dairying/economics , Ethiopia , Farms/statistics & numerical data , Female , Food-Processing Industry/economics , Milk/economics
5.
BMJ Open ; 9(6): e026652, 2019 06 27.
Article in English | MEDLINE | ID: mdl-31253615

ABSTRACT

OBJECTIVES: Traditional methods for creating food composition tables struggle to cope with the large number of products and the rapid pace of change in the food and drink marketplace. This paper introduces foodDB, a big data approach to the analysis of this marketplace, and presents analyses illustrating its research potential. DESIGN: foodDB has been used to collect data weekly on all foods and drinks available on six major UK supermarket websites since November 2017. As of June 2018, foodDB has 3 193 171 observations of 128 283 distinct food and drink products measured at multiple timepoints. METHODS: Weekly extraction of nutrition and availability data of products was extracted from the webpages of the supermarket websites. This process was automated with a codebase written in Python. RESULTS: Analyses using a single weekly timepoint of 97 368 total products in March 2018 identified 2699 ready meals and pizzas, and showed that lower price ready meals had significantly lower levels of fat, saturates, sugar and salt (p<0.001). Longitudinal analyses of 903 pizzas revealed that 10.8% changed their nutritional formulation over 6 months, and 29.9% were either discontinued or new market entries. CONCLUSIONS: foodDB is a powerful new tool for monitoring the food and drink marketplace, the comprehensive sampling and granularity of collection provides power for revealing analyses of the relationship between nutritional quality and marketing of branded foods, timely observation of product reformulation and other changes to the food marketplace.


Subject(s)
Commerce/statistics & numerical data , Consumer Health Information/statistics & numerical data , Dietary Fats/analysis , Dietary Sucrose/analysis , Fast Foods/analysis , Food-Processing Industry , Sodium Chloride, Dietary/analysis , Data Collection , Databases, Factual , Fast Foods/economics , Food Labeling , Food-Processing Industry/economics , Humans , Longitudinal Studies , Marketing , Meals , Nutrition Policy , Nutritional Status , Nutritive Value , United Kingdom/epidemiology
7.
Food Funct ; 9(9): 4888-4896, 2018 Sep 19.
Article in English | MEDLINE | ID: mdl-30167607

ABSTRACT

This work addresses the role of different by-products derived from the industrial extraction of orange juice in a possible anti-inflammatory effect in mice with colitis induced by dextran sulfate sodium (DSS). Fresh orange residue (FOR), dry orange residue (DOR), orange liqueur (OL) and animal feed (AF), as well as commercial citrus pectin (CP), were administered to C57BL/6J mice for 15 days before starting the DSS treatment. Analysis of macroscopic parameters such as the Disease Activity Index (DAI) and the colonic weight/length ratio revealed an anti-inflammatory effect following intake of FOR, AF or CP. Moreover, q-PCR of RNA from colonic tissue indicated measurable changes in the expression of TNF-α, IL-1ß, iNOS, and intercellular adhesion molecules ICAM I, as well as in intestinal barrier proteins such as MUC-3, occludin, and ZO-1. Pectin, phenolic compounds and/or Maillard reaction products formed at initial steps were identified as relevant components exerting the ascribed beneficial effects. Our findings could open up the further application of a variety of orange by-products as food supplements in the potential amelioration of inflammatory bowel diseases.


Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Biological Products/therapeutic use , Citrus sinensis/chemistry , Colitis, Ulcerative/prevention & control , Dietary Supplements , Disease Models, Animal , Fruit/chemistry , Animals , Anti-Inflammatory Agents, Non-Steroidal/analysis , Anti-Inflammatory Agents, Non-Steroidal/chemistry , Anti-Inflammatory Agents, Non-Steroidal/economics , Biological Products/analysis , Biological Products/chemistry , Biological Products/economics , Colitis, Ulcerative/immunology , Colitis, Ulcerative/metabolism , Colitis, Ulcerative/pathology , Colon/immunology , Colon/metabolism , Colon/pathology , Cytokines/antagonists & inhibitors , Cytokines/genetics , Cytokines/metabolism , Dextran Sulfate , Food-Processing Industry/economics , Fruit/economics , Gene Expression Regulation , Glycation End Products, Advanced/analysis , Glycation End Products, Advanced/economics , Glycation End Products, Advanced/therapeutic use , Industrial Waste/analysis , Industrial Waste/economics , Intestinal Mucosa/immunology , Intestinal Mucosa/metabolism , Intestinal Mucosa/pathology , Male , Mice, Inbred C57BL , Pectins/analysis , Pectins/economics , Pectins/therapeutic use , Phenols/analysis , Phenols/economics , Phenols/therapeutic use , Protective Agents/analysis , Protective Agents/chemistry , Protective Agents/economics , Protective Agents/therapeutic use , Specific Pathogen-Free Organisms
8.
PLoS Med ; 15(4): e1002551, 2018 04.
Article in English | MEDLINE | ID: mdl-29634725

ABSTRACT

BACKGROUND: Sodium consumption is a modifiable risk factor for higher blood pressure (BP) and cardiovascular disease (CVD). The US Food and Drug Administration (FDA) has proposed voluntary sodium reduction goals targeting processed and commercially prepared foods. We aimed to quantify the potential health and economic impact of this policy. METHODS AND FINDINGS: We used a microsimulation approach of a close-to-reality synthetic population (US IMPACT Food Policy Model) to estimate CVD deaths and cases prevented or postponed, quality-adjusted life years (QALYs), and cost-effectiveness from 2017 to 2036 of 3 scenarios: (1) optimal, 100% compliance with 10-year reformulation targets; (2) modest, 50% compliance with 10-year reformulation targets; and (3) pessimistic, 100% compliance with 2-year reformulation targets, but with no further progress. We used the National Health and Nutrition Examination Survey and high-quality meta-analyses to inform model inputs. Costs included government costs to administer and monitor the policy, industry reformulation costs, and CVD-related healthcare, productivity, and informal care costs. Between 2017 and 2036, the optimal reformulation scenario achieving the FDA sodium reduction targets could prevent approximately 450,000 CVD cases (95% uncertainty interval: 240,000 to 740,000), gain approximately 2.1 million discounted QALYs (1.7 million to 2.4 million), and produce discounted cost savings (health savings minus policy costs) of approximately $41 billion ($14 billion to $81 billion). In the modest and pessimistic scenarios, health gains would be 1.1 million and 0.7 million QALYS, with savings of $19 billion and $12 billion, respectively. All the scenarios were estimated with more than 80% probability to be cost-effective (incremental cost/QALY < $100,000) by 2021 and to become cost-saving by 2031. Limitations include evaluating only diseases mediated through BP, while decreasing sodium consumption could have beneficial effects upon other health burdens such as gastric cancer. Further, the effect estimates in the model are based on interventional and prospective observational studies. They are therefore subject to biases and confounding that may have influenced also our model estimates. CONCLUSIONS: Implementing and achieving the FDA sodium reformulation targets could generate substantial health gains and net cost savings.


Subject(s)
Cost-Benefit Analysis , Food Handling , Food, Formulated , Health Policy , Hypertension/prevention & control , Sodium, Dietary/administration & dosage , Computer Simulation , Food Handling/economics , Food Handling/standards , Food, Formulated/analysis , Food, Formulated/economics , Food-Processing Industry/economics , Food-Processing Industry/legislation & jurisprudence , Goals , Health Policy/economics , Humans , Nutrition Policy/economics , Nutrition Surveys , Risk Factors , United States , United States Food and Drug Administration/legislation & jurisprudence , United States Food and Drug Administration/standards
9.
Food Funct ; 9(4): 2121-2135, 2018 Apr 25.
Article in English | MEDLINE | ID: mdl-29644368

ABSTRACT

The present investigation was aimed to study the effect of detoxification on the nutrients and antinutrients of wild apricot kernel followed by its hypocholesterolemic effect in male Wistar albino rats. The results revealed a non-significant (p > 0.05) effect of detoxification on the proximate composition except total carbohydrates and protein content. However, detoxification led to a significant (p < 0.05) decrease in l-ascorbic acid (76.82%), ß-carotene (25.90%), dietary fiber constituents (10.51-28.92%), minerals (4.76-31.08%) and antinutritional factors (23.92-77.05%) (phenolics, tannins, trypsin inhibitor activity, saponins, phytic acid, alkaloids, flavonoids, oxalates) along with the complete removal (100%) of bitter and potentially toxic hydrocyanic acid (HCN). The quality parameters of kernel oil indicated no adverse effects of detoxification on free fatty acids, lipase activity, acid value and peroxide value, which remained well below the maximum permissible limit. Blood lipid profile demonstrated that the detoxified apricot kernel group exhibited significantly (p < 0.05) increased levels of HDL-cholesterol (48.79%) and triglycerides (15.09%), and decreased levels of total blood cholesterol (6.99%), LDL-C (22.95%) and VLDL-C (7.90%) compared to that of the raw (untreated) kernel group. Overall, it can be concluded that wild apricot kernel flour could be detoxified efficiently by employing a simple, safe, domestic and cost-effective method, which further has the potential for formulating protein supplements and value-added food products.


Subject(s)
Anticholesteremic Agents/analysis , Antimetabolites/analysis , Food Contamination/prevention & control , Food Handling , Foods, Specialized/analysis , Prunus armeniaca/chemistry , Seeds/chemistry , Animals , Anticholesteremic Agents/adverse effects , Anticholesteremic Agents/economics , Anticholesteremic Agents/therapeutic use , Antimetabolites/adverse effects , Food Contamination/economics , Food Ingredients/adverse effects , Food Ingredients/analysis , Food Ingredients/economics , Food-Processing Industry/economics , Foods, Specialized/adverse effects , Foods, Specialized/economics , Humans , Hydrogen Cyanide/adverse effects , Hydrogen Cyanide/analysis , Hypercholesterolemia/blood , Hypercholesterolemia/prevention & control , Industrial Waste/adverse effects , Industrial Waste/analysis , Industrial Waste/economics , Male , Nutritive Value , Particle Size , Prunus armeniaca/adverse effects , Prunus armeniaca/growth & development , Random Allocation , Rats, Wistar , Reproducibility of Results , Seeds/adverse effects , Seeds/growth & development , Wilderness , beta Carotene/analysis , beta Carotene/therapeutic use
10.
Food Funct ; 9(4): 1978-1992, 2018 Apr 25.
Article in English | MEDLINE | ID: mdl-29594287

ABSTRACT

Citrus medica (Citron) is an underutilized fruit plant having various bioactive components in all parts of the plant. The major bioactive compounds present are iso-limonene, citral, limonene, phenolics, flavonones, vitamin C, pectin, linalool, decanal, and nonanal, accounting for several health benefits. Pectin and heteropolysachharides also play a major role as dietary fibers. The potential impact of citron and its bioactive components to prevent or reverse destructive deregulated processes responsible for certain diseases has attracted different researchers' attention. The fruit has numerous nutraceutical benefits, proven by pharmacological studies; for example, anti-catarrhal, capillary protector, anti-hypertensive, diuretic, antibacterial, antifungal, anthelmintic, antimicrobial, analgesic, strong antioxidant, anticancerous, antidiabetic, estrogenic, antiulcer, cardioprotective, and antihyperglycemic. The present review explores new insights into the benefits of citron in various body parts. Throughout the world, citron has been used in making carbonated drinks, alcoholic beverages, syrup, candied peels, jams, marmalade, cordials, and many other value added products, which suggests it is an appropriate raw material to develop healthy processed food. In the present review, the fruit taxonomical classification, beneficial phytochemicals, antioxidant activities, and health benefits are discussed.


Subject(s)
Chronic Disease/prevention & control , Citrus , Fruit , Functional Food , Animals , Antineoplastic Agents, Phytogenic/analysis , Antineoplastic Agents, Phytogenic/economics , Antineoplastic Agents, Phytogenic/isolation & purification , Antineoplastic Agents, Phytogenic/therapeutic use , Antioxidants/analysis , Antioxidants/economics , Antioxidants/isolation & purification , Antioxidants/therapeutic use , Citrus/chemistry , Citrus/economics , Dietary Supplements/analysis , Dietary Supplements/economics , Food Additives/chemistry , Food Additives/economics , Food Additives/isolation & purification , Food Additives/therapeutic use , Food-Processing Industry/economics , Fruit/chemistry , Fruit/economics , Humans , Industrial Waste/analysis , Industrial Waste/economics , Nutritive Value , Phytochemicals/analysis , Phytochemicals/economics , Phytochemicals/isolation & purification , Phytochemicals/therapeutic use , Plant Extracts/chemistry , Plant Extracts/economics , Plant Extracts/isolation & purification , Plant Extracts/therapeutic use
11.
Food Funct ; 9(4): 2051-2069, 2018 Apr 25.
Article in English | MEDLINE | ID: mdl-29589631

ABSTRACT

This study was aimed at investigating the chemical composition (proximate, minerals, fatty acids and phenolic compounds) and the in vitro (antimicrobial, radical scavenging, anti-acetylcholinesterase and protein denaturing activities) and in vivo (anti-diabetic and histo-protective effects in alloxan-induced diabetic mice) biological activities of broad bean pods (BBPs), a food waste by-product material. The results showed that BBPs have high dietary fiber (57.46%), carbohydrate (18.93%) and protein (13.81%) content versus low fat content (<1%) contributing to a low energy value of 139.24 kcal per 100 g. Profiling of fatty acids showed an abundance of the essential polyunsaturated α-linolenic and linoleic acids, exhibiting an excellent nutritional quality as revealed by their low atherogenic and thrombogenic indices and their hypocholesterolemic properties. The methanol extract which exhibited the highest total phenolic, flavonoid and tannin contents was found to be the most active extract in terms of antimicrobial and anti-radical activities. In alloxan-induced diabetic mice, the oral administration of a methanol extract (500 mg per kg bw) attenuated the elevated levels of serum alanine aminotransferase (ALA), aspartate aminotransferase (AST), and alkaline phosphatase activities, and urea, uric acid, and creatinine. It effectively normalized the status of lipid profiles, mitigated oxidative stress through the activation of antioxidant enzymes (CAT, GPx and SOD), and alleviated oxidative stress-mediated histopathological changes in the pancreas, liver, kidney and testis. Compositional analysis by HPLC-PDA-ESI-MS/MS revealed the presence of flavan-3-ols (catechin, epicatechin and their derivatives), flavones (apigenin derivatives) and flavonols (glycosides of quercetin and kaempferol), among others. These findings suggest that BBPs may be an effective functional food for the management of diabetes and its complications.


Subject(s)
Diabetes Mellitus, Experimental/diet therapy , Dietary Supplements , Fruit/chemistry , Hypoglycemic Agents/therapeutic use , Industrial Waste/analysis , Plant Extracts/therapeutic use , Vicia faba/chemistry , Animals , Anti-Bacterial Agents/chemistry , Anti-Bacterial Agents/economics , Anti-Bacterial Agents/isolation & purification , Anti-Bacterial Agents/therapeutic use , Antioxidants/chemistry , Antioxidants/economics , Antioxidants/isolation & purification , Antioxidants/therapeutic use , Biomarkers/blood , Diabetes Mellitus, Experimental/blood , Diabetes Mellitus, Experimental/pathology , Dietary Supplements/analysis , Disk Diffusion Antimicrobial Tests , Food-Processing Industry/economics , Fruit/economics , Fruit/growth & development , Humans , Hypoglycemic Agents/chemistry , Hypoglycemic Agents/economics , Hypoglycemic Agents/isolation & purification , Industrial Waste/economics , Male , Methanol/chemistry , Mice , Nutritive Value , Oxidative Stress , Plant Extracts/chemistry , Plant Extracts/economics , Plant Extracts/isolation & purification , Random Allocation , Solvents/chemistry , Tunisia , Vicia faba/growth & development
12.
Biol Pharm Bull ; 41(2): 208-212, 2018.
Article in English | MEDLINE | ID: mdl-29386480

ABSTRACT

Mume fruit, the Japanese apricot (Prunus mume SIEB. et ZUCC.), is popular in Japan and is mostly consumed in the pickled form called umeboshi. This fruit is known to have anti-microbial properties, but the principal constituents responsible for the antimicrobial properties have not yet been elucidated. We investigated the antimicrobial activities of the phenolic compounds in P. mume against enterobacteria. In this study, growth inhibitory activities were measured as an index of the antibacterial activities. The phenolic compounds were prepared from a byproduct of umeboshi called umesu or umezu (often translated as "mume vinegar"). Umesu or umezu phenolics (UP) contain approximately 20% phenolic compounds with p-coumaric acid as a standard and do not contain citric acid. We observed the inhibitory effects of UP against the growth of some enterobacteria, at a relatively high concentration (1250-5000 µg/mL). Alkali hydrolysates of UP (AHUP) exhibited similar antibacterial activities, but at much lower concentrations of 37.5-300 µg/mL. Since AHUP comprises hydroxycinnamic acids such as caffeic acid, p-coumaric acid, and ferulic acid, the antibacterial activities of each of these acids were examined. Our study shows that the phenolic compounds in P. mume other than citric acid contribute to its antimicrobial activity against enterobacteria in the digestive tract.


Subject(s)
Anti-Bacterial Agents/pharmacology , Drug Discovery , Enterobacteriaceae/drug effects , Food, Preserved/analysis , Fruit/chemistry , Phenols/pharmacology , Prunus/chemistry , Anti-Bacterial Agents/chemistry , Anti-Bacterial Agents/isolation & purification , Chromatography, High Pressure Liquid , Coumaric Acids/chemistry , Coumaric Acids/isolation & purification , Coumaric Acids/pharmacology , Enterobacteriaceae/growth & development , Ethnopharmacology , Food-Processing Industry/economics , Freeze Drying , Hydrolysis/drug effects , Indicators and Reagents/chemistry , Industrial Waste/analysis , Industrial Waste/economics , Japan , Medicine, East Asian Traditional , Microbial Sensitivity Tests , Molecular Structure , Phenols/chemistry , Phenols/isolation & purification , Sodium Hydroxide/chemistry
13.
Int J Food Sci Nutr ; 69(2): 165-175, 2018 Mar.
Article in English | MEDLINE | ID: mdl-28691595

ABSTRACT

The aim of this study was to apply the enzymatic treatment and fermentation by Pediococcus acidilactici BaltBio01 strain for industrial cereal by-products conversion to food/feed bioproducts with high amount of probiotic lactic acid bacteria (LAB). LAB propagated in potato media and spray-dried remained viable during 12 months (7.0 log10 cfu/g) of storage and was used as a starter for cereal by-products fermentation. The changes of microbial profile, biogenic amines (BAs), mycotoxins, lactic acid (L+/D-), lignans and alkylresorcinols (ARs) contents in fermented cereal by-product were analysed. Cereal by-products enzymatic hydrolysis before fermentation allows to obtain a higher count of LAB during fermentation. Fermentation with P. acidilactici reduce mycotoxins content in fermented cereal by-products. According to our results, P. acidilactici multiplied in potato juice could be used for cereal by-products fermentation, as a potential source to produce safer food/feed bioproduct with high amount of probiotic LAB for industrial production.


Subject(s)
Animal Feed/microbiology , Edible Grain/metabolism , Fermented Foods/microbiology , Food Additives/metabolism , Hydrolases/metabolism , Pediococcus acidilactici/metabolism , Probiotics/metabolism , Alkylation , Animal Feed/adverse effects , Animal Feed/analysis , Animal Feed/economics , Animals , Biogenic Amines/adverse effects , Biogenic Amines/analysis , Biogenic Amines/metabolism , Edible Grain/adverse effects , Edible Grain/chemistry , Edible Grain/economics , Fermentation , Fermented Foods/adverse effects , Fermented Foods/analysis , Fermented Foods/economics , Food Additives/adverse effects , Food Additives/chemistry , Food Additives/economics , Food Contamination/prevention & control , Food Handling , Food-Processing Industry/economics , Humans , Hydrolases/adverse effects , Hydrolysis , Industrial Waste/economics , Latvia , Lignans/adverse effects , Lignans/analysis , Lignans/metabolism , Microbial Viability , Mycotoxins/isolation & purification , Mycotoxins/metabolism , Mycotoxins/toxicity , Pediococcus acidilactici/growth & development , Probiotics/adverse effects , Resorcinols/adverse effects , Resorcinols/analysis , Resorcinols/metabolism
14.
J Physiol Biochem ; 74(1): 101-110, 2018 Feb.
Article in English | MEDLINE | ID: mdl-28677073

ABSTRACT

Nowadays, the strong relationship between diet and health is well known. Although the primary role of diet is to provide nutrients to fulfill metabolic requirements, the use of foods to improve health and the state of well-being is an idea increasingly accepted by society in the last three decades. During the last years, an important number of scientific advances have been achieved in this field and, although in some situations, it is difficult to establish a distinction between "harmful" and "good" bacteria, experts agree in classifying the genera Bifidobacterium and Lactobacillus as beneficial bacteria. Thus, several strategies can be used to stimulate the proliferation of these beneficial intestinal bacteria, being one of them the consumption of prebiotics. The development of new prebiotics, with added functionality, is one of the most serious challenges shared not only by the scientific community but also by the food industry. The objective of this work was to evaluate the potential prebiotic effect of red and white grape residues, both obtained during the winemaking process. For such purpose, an in vitro study with pure cultures of Lactobacillus and Bifidobacterium was first conducted. Secondly, a study with mixed cultures using human fecal inocula was carried out in a simulator of the distal part of the colon. The obtained results showed an increase in the Lactobacillus and Bifidobacterium population, indicating that these ingredients are serious candidates to be considered as prebiotics.


Subject(s)
Gastrointestinal Microbiome , Models, Biological , Pigments, Biological/metabolism , Plant Components, Aerial/chemistry , Plant Extracts/metabolism , Prebiotics , Vitis/chemistry , Adult , Animals , Bifidobacterium/classification , Bifidobacterium/growth & development , Bifidobacterium/isolation & purification , Bifidobacterium/metabolism , Digestion , Feces/microbiology , Female , Fermentation , Food-Processing Industry/economics , Humans , Industrial Waste/analysis , Industrial Waste/economics , Lactobacillus/classification , Lactobacillus/growth & development , Lactobacillus/isolation & purification , Lactobacillus/metabolism , Male , Microbial Viability , Molecular Typing , Plant Components, Aerial/metabolism , Plant Extracts/economics , Prebiotics/economics , Spain , Vitis/metabolism
15.
Eur J Nutr ; 57(2): 761-772, 2018 Mar.
Article in English | MEDLINE | ID: mdl-28004272

ABSTRACT

INTRODUCTION: Diabetic nephropathy (DN) is an important microvascular complication of uncontrolled diabetes. The features of DN include albuminuria, extracellular matrix alterations, and progressive renal insufficiency. Rice bran protein hydrolysates (RBPs) have been reported to have antihyperglycemic, lipid-lowering, and anti-inflammatory effects in diabetic rats. Our study was to investigate the renoprotective effects of RBP in diabetic animals and mesangial cultured cells. METHODS: Eight-week-old male db/m and db/db mice were orally treated with tap water or RBP (100 or 500 mg/kg/day) for 8 weeks. At the end of the experiment, diabetic nephropathy in kidney tissues was investigated for histological, ultrastructural, and clinical chemistry changes, and biomarkers of angiogenesis, fibrosis, inflammation, and antioxidant in kidney were analyzed by Western blotting. Protection against proangiogenic proteins and induction of cytoprotection by RBP in cultured mesangial cells was evaluated. RESULTS: RBP treatment improved insulin sensitivity, decreased elevated fasting serum glucose levels, and improved serum lipid levels and urinary albumin/creatinine ratios in diabetic mice. RBP ameliorated the decreases in podocyte slit pore numbers, thickening of glomerular basement membranes, and mesangial matrix expansion and suppressed elevation of MCP-1, ICAM-1, HIF-1α, VEGF, TGF-ß, p-Smad2/3, and type IV collagen expression. Moreover, RBP restored suppressed antioxidant Nrf2 and HO-1 expression. In cultured mesangial cells, RBP inhibited high glucose-induced angiogenic protein expression and induced the expression of Nrf2 and HO-1. CONCLUSION: RBP attenuates the progression of diabetic nephropathy and restored renal function by suppressing the expression of proangiogenic and profibrotic proteins, inhibiting proinflammatory mediators, and restoring the antioxidant and cytoprotective system.


Subject(s)
Diabetes Mellitus, Type 2/diet therapy , Diabetic Nephropathies/prevention & control , Hypoglycemic Agents/therapeutic use , Insulin Resistance , Oryza/chemistry , Plant Proteins, Dietary/therapeutic use , Protein Hydrolysates/therapeutic use , Animals , Biomarkers/blood , Biomarkers/metabolism , Cell Line , Diabetes Mellitus, Type 2/complications , Diabetes Mellitus, Type 2/metabolism , Diabetes Mellitus, Type 2/pathology , Diabetic Nephropathies/immunology , Food-Processing Industry/economics , Hyperglycemia/prevention & control , Hypoglycemic Agents/economics , Hypoglycemic Agents/metabolism , Industrial Waste/analysis , Industrial Waste/economics , Kidney/immunology , Kidney/metabolism , Kidney/pathology , Kidney/ultrastructure , Male , Mesangial Cells/immunology , Mesangial Cells/metabolism , Mesangial Cells/pathology , Mesangial Cells/ultrastructure , Mice, Mutant Strains , Microscopy, Electron, Transmission , Plant Epidermis/chemistry , Plant Proteins, Dietary/economics , Plant Proteins, Dietary/metabolism , Protein Hydrolysates/economics , Protein Hydrolysates/metabolism , Renal Insufficiency/complications , Renal Insufficiency/immunology , Renal Insufficiency/prevention & control , Seeds/chemistry , Thailand
16.
Food Sci Technol Int ; 24(2): 97-109, 2018 Mar.
Article in English | MEDLINE | ID: mdl-28956454

ABSTRACT

This study aims at investigating pectin lyase bioproduction in submerged fermentation with synthetic medium and agro-industrial residues, using the filamentous fungus Aspergillus brasiliensis. The maximum pectin lyase activity in a synthetic medium (42 g/l pectin, 40 g/l yeast extract, and 0.02 g/l iron sulfate) was 31 U/ml, and 46 U/ml in the agro-industrial medium (160 g/l orange peel, 150 g/l corn steep liquor, and 300 g/l parboiled rice water), obtained over 60 and 124 h of bioproduction, 180 r/min, 30 ℃, pHinitial 5.5, and 5·106 spores/ml, respectively. Partial characterization of pectin lyase crude enzyme extract obtained from the synthetic medium and the one made of agro-industrial residues showed optimum conditions at pH of 5.5 and 4.5 and temperatures of 37 and 55 ℃, respectively. The Ed obtained was 3.13 and 9.15 kJ/mol, and the half-life time (t1/2) was 5.71 and 80 h at 55 ℃ for pectin lyase produced in synthetic and agro-industrial medium, respectively.


Subject(s)
Aspergillus/enzymology , Biotechnology/methods , Fungal Proteins/biosynthesis , Industrial Waste/analysis , Polysaccharide-Lyases/biosynthesis , Agriculture/economics , Aspergillus/growth & development , Aspergillus/metabolism , Biotechnology/trends , Brazil , Citrus sinensis/chemistry , Crops, Agricultural/chemistry , Crops, Agricultural/economics , Enzyme Stability , Fermentation , Food Handling , Food-Processing Industry/economics , Fruit/chemistry , Fruit/economics , Fungal Proteins/chemistry , Fungal Proteins/economics , Fungal Proteins/genetics , Hot Temperature , Hydrogen-Ion Concentration , Industrial Waste/economics , Kinetics , Oryza/chemistry , Polysaccharide-Lyases/chemistry , Polysaccharide-Lyases/economics , Polysaccharide-Lyases/genetics , Recombinant Proteins/biosynthesis , Recombinant Proteins/chemistry , Recombinant Proteins/economics , Recombinant Proteins/isolation & purification , Zea mays/chemistry
17.
Food Sci Technol Int ; 24(3): 232-241, 2018 Apr.
Article in English | MEDLINE | ID: mdl-29199453

ABSTRACT

Soaking of legumes results in the loss of macronutrients, micronutrients and phytochemicals. Fibre, protein and phytochemicals found in legumes exert emulsifying activity that may improve the structure and texture of gluten-free bread. The legume soaking water of haricot beans, garbanzo chickpeas, whole green lentils, split yellow peas and yellow soybeans were tested in this study for functional properties and use as food ingredients. Composition, physicochemical properties and effect on the quality of gluten-free bread were determined for each legume soaking water. Haricot beans and split yellow peas released the highest amount of solids in the legume soaking water: 1.89 and 2.38 g/100 g, respectively. Insoluble fibre was the main constituent of haricot beans legume soaking water, while water-soluble carbohydrates and protein were the major fraction of split yellow peas. High quantities of phenolics (∼400 µg/g) and saponins (∼3 mg/g) were found in the legume soaking water of haricot beans, whole green lentils and split yellow peas. High emulsifying activity (46 and 50%) was found for the legume soaking water of garbanzo chickpeas and split yellow peas, probably due to their protein content and high ratio of water-soluble carbohydrates to dry matter. Such activity resulted in softer texture of the gluten-free bread. A homogeneous structure of crumb pores was found for split yellow peas, opposing that of whole green lentils. A balance between the contents of yeast nutrients and antinutrients was the likely basis of the different appearances.


Subject(s)
Bread/analysis , Cooking , Diet, Gluten-Free , Emulsifying Agents/chemistry , Fabaceae/chemistry , Seeds/chemistry , Water/chemistry , Bread/economics , Bread/microbiology , Cooking/economics , Diet, Gluten-Free/economics , Dietary Carbohydrates/analysis , Dietary Carbohydrates/economics , Dietary Fiber/analysis , Dietary Fiber/economics , Dietary Proteins/analysis , Dietary Proteins/chemistry , Dietary Proteins/economics , Emulsifying Agents/analysis , Emulsifying Agents/economics , Fabaceae/metabolism , Fermentation , Food Quality , Food-Processing Industry/economics , Humans , Industrial Waste/analysis , Industrial Waste/economics , New Zealand , Nutritive Value , Phenols/analysis , Phenols/chemistry , Phenols/economics , Pigments, Biological/analysis , Pigments, Biological/biosynthesis , Saccharomyces cerevisiae/growth & development , Saccharomyces cerevisiae/metabolism , Saponins/analysis , Saponins/chemistry , Saponins/economics , Seeds/metabolism , Species Specificity
18.
Food Sci Technol Int ; 24(3): 251-263, 2018 Apr.
Article in English | MEDLINE | ID: mdl-29207886

ABSTRACT

Wheat bread was enriched with 6%, 10% and 15% dried and milled grape pomace flour from two grape cultivars: 'Merlot' and 'Zelen'. Rheological, textural, sensory and antioxidant properties of the enriched dough and bread were evaluated, and compared to control samples. Grape cultivar had significant impact on the rheological characteristics of the dough, and on the sensory and antioxidant properties of the final bread. Development time and dough stability were longer when 'Merlot' grape pomace flour was added compared to 'Zelen' grape pomace flour and the control. Grape pomace flour addition affected bread volume, firmness, crumb and crust colour, and odour and taste intensity. Moreover, grape pomace flour addition resulted in a stickier and less springy crumb texture, and some negative sensorial properties, such as increased intensity of aftertaste and sand feeling in the mouth. The phenolic content and antioxidant activity of bread were positively correlated with grape pomace flour addition ( r = 0.987, p = 0.01 and r = 0.941, p = 0.01 between phenolic content and ferric reducing antioxidant power and phenolic content and 2,2-diphenyl-1-picrylhydrazyl, respectively). The highest total phenolic contents were 5.92 mg gallic acid equivalents (GAE)/g dw for 'Merlot' and 3.65 mg gallic acid equivalents /g dw for 'Zelen', which were seen for the bread prepared with the highest grape pomace flour addition (15%). The highest antioxidant activity determined by the 2,2-diphenyl-1-picrylhydrazyl and ferric reducing antioxidant power assays were seen for the bread prepared with the highest 'Merlot' grape pomace flour addition (15%). Dough characteristic and sensory profile are strongly influenced by cultivar of grape pomace flour. Based on results of sensory profiling, the variety 'Zelen' is suggested for use.


Subject(s)
Antioxidants/analysis , Bread/analysis , Flour/analysis , Food Quality , Fruit/chemistry , Industrial Waste/analysis , Vitis/chemistry , Bread/economics , Crops, Agricultural/chemistry , Crops, Agricultural/growth & development , Food Preferences , Food-Processing Industry/economics , Humans , Industrial Waste/economics , Maillard Reaction , Nutritive Value , Odorants , Rheology , Sensation , Slovenia , Species Specificity , Taste , Triticum/chemistry , Vitis/growth & development
19.
Food Sci Technol Int ; 24(3): 187-197, 2018 Apr.
Article in English | MEDLINE | ID: mdl-29141452

ABSTRACT

The quality parameters of sauerkraut fermented using Lactobacillus paracasei in terms of its lactic acid bacteria count, texture, colour and biochemical properties were studied. As a starter culture L. paracasei grown in tofu whey was used for sauerkraut fermentation. The experiments were planned using central composite rotatable design of response surface methodology for input variables - culture volume (ml), fermentation time (days) and salt concentration (g/100 g). The linear and interactive effect of variables on responses was understood by statistically significant (p < 0.01) second-order models. Amongst all the input variables culture volume was found to have an overwhelming effect over all the responses. There was a significant (p < 0.01) increase in the lactic acid bacteria count of finished product; it was less hard but there was a departure in colour from the traditional product. The optimized condition for sauerkraut fermentation in terms of culture volume (ml), fermentation time (day) and salt concentration (g/100 g) was 30 ml, 28 days and 1 g/100 g, respectively. It was also observed that phenolics content was better in starter culture sauerkraut over the one traditionally prepared.


Subject(s)
Brassica/chemistry , Fermented Foods/analysis , Food Quality , Food, Preserved/analysis , Lacticaseibacillus paracasei/growth & development , Soy Foods/microbiology , Vegetables/chemistry , Antioxidants/analysis , Antioxidants/metabolism , Bacterial Load , Brassica/metabolism , Brassica/microbiology , Brassica/ultrastructure , Fermentation , Fermented Foods/economics , Fermented Foods/microbiology , Food Preferences , Food, Preserved/economics , Food, Preserved/microbiology , Food-Processing Industry/economics , Humans , Hydrogen-Ion Concentration , India , Industrial Waste/analysis , Industrial Waste/economics , Lacticaseibacillus paracasei/isolation & purification , Lacticaseibacillus paracasei/metabolism , Microscopy, Electron, Scanning , Phenols/analysis , Phenols/metabolism , Pigments, Biological/analysis , Pigments, Biological/biosynthesis , Sensation , Sodium Chloride, Dietary/analysis , Soy Foods/economics , Time Factors , Vegetables/metabolism , Vegetables/microbiology , Vegetables/ultrastructure
20.
Food Sci Technol Int ; 24(3): 198-208, 2018 Apr.
Article in English | MEDLINE | ID: mdl-29169267

ABSTRACT

Cereal bars are nutritious food composed of several ingredients including dry raw and agglutinative ingredients. The objective of this study was to evaluate the effect of pear apple and date fibres, from cooked fruit co-product, addition on the physico-chemical textural and sensory properties of cereal bars. First, five formulations containing an amount of 10% of co-products and commercial fibre, used as a reference, were elaborated and their physico-chemical composition was determined. Second, to determine the acceptability of consumer, apple fibre co-products were added (6, 10 and 14%). Products were evaluated for their texture using a texturometer and sensory characteristics using an acceptance test. Results showed that physico-chemical composition of cereal bars elaborated with co-products was slightly different compared to those elaborated with commercial fibre. All bars have low water activity levels (∼0.470) and interesting energy (300 kcal/100 g bar). External appearance revealed a darker colour (L*:∼42/a*:∼8/b*:∼20). There were no significant differences (P > 0.05) in texture values (hardness: 40.8 N; cohesiveness: 0.34; springiness: 0.60; chewiness: 8.30 N) between cereal bars prepared with pear co-product and wheat bran. Acceptance test confirms the formulation used for cereals bars and showed that incorporation of 10% of co-product produced cereal bars with the highest acceptability. Sensory characteristics revealed that appearance is the limiting factor for consumer acceptability, essentially for cereal bars containing pear co-product. Apple, pear and date co-products could be used successfully as a food ingredient to develop new formulations of cereal bars.


Subject(s)
Dietary Fiber/analysis , Edible Grain/chemistry , Fruit/chemistry , Industrial Waste/analysis , Malus/chemistry , Phoeniceae/chemistry , Pyrus/chemistry , Belgium , Chemical Phenomena , Dietary Fiber/economics , Fast Foods/analysis , Fast Foods/economics , Food Preferences , Food Quality , Food, Preserved/analysis , Food, Preserved/economics , Food-Processing Industry/economics , Fruit/economics , Fruit/metabolism , Humans , Industrial Waste/economics , Maillard Reaction , Malus/metabolism , Nutritive Value , Phoeniceae/metabolism , Pigments, Biological/analysis , Pigments, Biological/biosynthesis , Pyrus/metabolism , Sensation , Water/analysis
SELECTION OF CITATIONS
SEARCH DETAIL
...