Human sound systems are shaped by post-Neolithic changes in bite configuration.

Linguistic diversity, now and in the past, is widely regarded to be independent of biological changes that took place after the emergence of Homo sapiens We show converging evidence from paleoanthropology, speech biomechanics, ethnography, and historical linguistics that labiodental sounds (such as "f" and "v") were innovated after the Neolithic. Changes in diet attributable to food-processing technologies modified the human bite from an edge-to-edge configuration to one that preserves adolescent overbite and overjet into adulthood. This change favored the emergence and maintenance of labiodentals. Our findings suggest that language is shaped not only by the contingencies of its history, but also by culturally induced changes in human biology.

One hundred years of commercial food carbohydrates in the United States.

Initiation and development of the industries producing specialty starches, modified food starches, high-fructose sweeteners, and food gums (hydrocolloids) over the past century provided major ingredients for the rapid and extensive growth of the processed food and beverage industries. Introduction of waxy maize starch and high-amylose corn starch occurred in the 1940s and 1950s, respectively. Development and growth of the modified food starch industry to provide ingredients with the functionalities required for the fast-growing processed food industry were rapid during the 1940s and 1950s. The various reagents used today for making cross-linked and stabilized starch products were introduced between 1942 and 1961. The initial report of enzyme-catalyzed isomerization of glucose to fructose was made in 1957. Explosive growth of high-fructose syrup manufacture and use occurred between 1966 and 1984. Maltodextrins were introduced between 1967 and 1973. Production of methylcelluloses and carboxymethylcelluloses began in the 1940s. The carrageenan industry began in the 1930s and grew rapidly in the 1940s and 1950s; the same is true of the development and production of alginate products. The guar gum industry developed in the 1940s and 1950s. The xanthan industry came into being during the 1950s and 1960s. Microcrystalline cellulose was introduced in the 1960s. Therefore, most carbohydrate food ingredients were introduced in about a 25 year period between 1940 and 1965. Exceptions are the introduction of maltodextrins and major developments in the high-fructose syrup industry, which occurred in the 1970s.

[History of gelatin extraction process and debates of French academic commissions (XIXth century)]. / Histoire des procédés d'extraction de la gelatine et débats des commissions académiques (XIXe siècle).

Since Papin (XVII th century) gelatine was expected to be substituted for meat in poor peoples' food. Its nutritional value was studied by academic Commissions, from 1803 to 1841. The question has been given up after 1870 when the growth in agricultural yield owing to fertilizer use made food shortage vanish. In this paper, successive extraction methods are examined, and Chevreul's participation in the academic debates (XIX th century) is emphasized.

Commentary: variability in workplace exposures and the design of efficient measurement and control strategies.

Kromhout et al.'s (1993) well-cited publication presented detailed information on statistical procedures to estimate the magnitude of exposure variability within and between workers, drawing from a large database on chemical exposures throughout industry. It convincingly demonstrated that the construct of homogeneous exposure groups often does not hold true and suggested ways to improve measurement strategies. The authors hit a rich vein of research, and many publications, not at least by the authors themselves, followed in the decade after publication. In recent years the principles of estimating the variation in exposure have been applied in new methods for optimization of sampling strategies, for compliance testing, for quantifying exposures in epidemiologic studies, and for identifying important sources of emissions and suggesting strategies for controlling exposures. Many occupational hygienists across the globe have adopted these new methods as powerful tools in their exposure assessment strategies.

[Grape sugar manufacture assays under Premier Empire]. / Essais de fabrication de sucre de raisin sous le Premier Empire.

The Continental Blockade was established by the Decree of Berlin (1806). Scientists, manufacturers, and politicians were interested in grape sugar as a substitute for cane sugar. Grape sugar had been extracted and refined by Proust (1754-1826), in Spain, on a laboratory scale. He was invited by the Government to search a way of producing grape sugar on an industrial scale. As a scientist, he accompanied manufacturers in their assays. The matter is closed about 1811. It throws light on aspects of scientist's relationship, and part of authorities in the birth and failure of an agricultural industry. It signs the transition from an economic system directed by the Government to a system managed by manufactuers. This story forcasts the partition between scientists and manufacturers which will increase in France during all the century. As his compatriot Volney, Proust was an ideologue, searching for basic, general laws and useful science.

Coca-Cola, caffeine, and mental deficiency: Harry Hollingworth and the Chattanooga trial of 1911.

Harry Hollingworth's 1911 investigation of the behavioral effects of caffeine is one of the earliest examples of psychological research contracted by a large corporation. The research was necessitated by a federal government suit against the Coca-Cola Company for marketing a beverage with a deleterious ingredient, namely, caffeine. Although Hollingworth's research played little role in the outcome of the Coca-Cola trials, it was important as a model of sophistication in experimental design. As such, it set a standard for psychopharmacological research. It also was particularly important in directing Hollingworth toward a life-long career in applied psychology.

Food safety--then and now. A Bicentennial study.

Although this is our Bicentennial year, effective measures to insure food safety date back less than a century. The first efforts toward reform were begun by Accum in England early in the nineteenth century, but they did not bear fruit there--in even a beginning form--until 1875, when Parliament passed the Sales of Food and Drug Act. Legislation came even later in the U.S.--not until the first Pure Food and Drugs Act became law in 1906, largely due to the unswerving efforts for almost twenty years of Harvey W. Wiley. Today, the scientific approach is applied in developing criteria for judging the safety of food and for regulations to insure that healthful, safe food reaches the consumer. Amendments to this law in 1938 and 1958 have further strengthened the protection the public is provided in its food supply. Today, the substances on the "GRAS" list are being examined individually to determine their safety when used in foods. However, the legalistic invoking of absolutes, as in the Delaney Clause of the 1958 amendments, goes beyond the limits of common sense. The challenge is to insure the benefits of science and technology without the loss of basic individual freedom.