ABSTRACT
The osteal alkaline phosphatase (AP) activity was examined in 167 Wistar rats with uncomplicated regeneration and traumatic osteomyelitis of the mandible, exposed to low-intensity He-Ne laser. Laser exposure stimulated the bone AP activity in the animals with traumatic osteomyelitis and uncomplicated regeneration, confirming the efficacy of therapy with He-Ne laser.
Subject(s)
Alkaline Phosphatase/radiation effects , Fractures, Open/radiotherapy , Laser Therapy , Mandibular Fractures/radiotherapy , Osteomyelitis/radiotherapy , Alkaline Phosphatase/metabolism , Animals , Bone and Bones/enzymology , Bone and Bones/radiation effects , Evaluation Studies as Topic , Fractures, Open/complications , Fractures, Open/enzymology , Mandibular Fractures/complications , Mandibular Fractures/enzymology , Osteomyelitis/enzymology , Osteomyelitis/etiology , Rats , Rats, Inbred Strains , Time FactorsABSTRACT
Investigations carried out in 60 patients with open fractures of long tubular bones in osteosynthesis with the Ilizarov apparatus indicated that alkaline phosphatase (AP) of granulocytes fully reflects the postoperative course. 10--24 hours following the trauma the level of AP in patients with grave injuries exceeds that in patients with slight ones. The differences are found to be reliable from the 1st to the 5th day after the injury.
