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1.
Med Sci Monit ; 30: e944553, 2024 May 19.
Article in English | MEDLINE | ID: mdl-38762751

ABSTRACT

BACKGROUND Scaphoid nonunion (SN) is a challenging condition in wrist pathology, often resulting in severe consequences if left untreated. Surgical intervention, particularly using vascularized bone grafts (VBGs), is a promising but uncertain approach. The 4+5 extensor compartment artery (ECA) pedicled graft, less commonly used for SN, has potential benefits due to its vascular supply and accessibility to the scaphoid. This study aimed to evaluate the effectiveness of the 4+5 ECA pedicled graft combined with headless compression screw fixation in treating avascular necrosis (AVN)-induced proximal pole SN. Radiological results, functional outcomes, and complications related to this method were assessed. MATERIAL AND METHODS This was a retrospective analysis of 19 proximal pole SN cases with AVN treated using the 4+5 ECA-VBG technique from 2016 to 2022. Patients underwent preoperative evaluation and postoperative follow-up for at least 1 year. Data on surgery, demographics, radiological assessments, and functional outcomes were recorded and analyzed statistically. RESULTS All patients achieved radiographic union within 8.5 weeks postoperatively, with revascularization of proximal pole necrosis. Significant improvements in functional outcomes were observed, including pain reduction, increased wrist range of motion, improved grip and pinch strength, and enhanced wrist scores. No major complications were reported. CONCLUSIONS The 4+5 ECA-VBG technique, with headless compression screw fixation, showed high success rates in treating AVN-induced proximal pole SN. This method offers comprehensive restoration of wrist function and minimal complications, making it a viable option for SN management, especially in AVN cases. Further research is needed to confirm these results and establish standardized protocols for SN treatment.


Subject(s)
Bone Transplantation , Fractures, Ununited , Osteonecrosis , Scaphoid Bone , Humans , Scaphoid Bone/surgery , Scaphoid Bone/injuries , Male , Retrospective Studies , Female , Adult , Fractures, Ununited/surgery , Osteonecrosis/surgery , Bone Transplantation/methods , Fracture Fixation, Internal/methods , Treatment Outcome , Middle Aged , Range of Motion, Articular , Young Adult , Adolescent , Bone Screws , Arteries/surgery
2.
Bull Hosp Jt Dis (2013) ; 82(2): 154-158, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38739664

ABSTRACT

We report the treatment of two patient with humeral fractures with one or more risk factors for nonunion. The first patient was elderly with a previously diagnosed central nervous sys-tem injury. The second elderly patient previously sustained a cerebral vascular accident affecting the fractured arm. The fracture was oblique in the proximal third of the humerus. We achieved bone healing non-operatively utilizing a spe-cialized plastic orthosis that included a deforming element made of dense foam. This device asymmetrically increases the soft tissue pressure around the fracture.


Subject(s)
Fracture Healing , Fractures, Ununited , Humeral Fractures , Orthotic Devices , Humans , Humeral Fractures/surgery , Humeral Fractures/physiopathology , Humeral Fractures/diagnostic imaging , Fractures, Ununited/surgery , Fractures, Ununited/physiopathology , Fractures, Ununited/etiology , Risk Factors , Male , Treatment Outcome , Aged , Female , Equipment Design , Aged, 80 and over , Radiography
3.
Injury ; 55(6): 111583, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38692209

ABSTRACT

INTRODUCTION: Bone grafts for scaphoid nonunion with deformity include cortcicocancellous or pure cancellous bone grafts. This study compared the outcomes between two types of bone grafts when employing a volar locking-plate in patients with scaphoid nonunion with dorsal intercalated segmental instability (DISI). PATIENTS AND METHODS: This retrospective study included 34 patients with scaphoid nonunion and DISI due to humpback deformity treated between March 2017 and January 2022. Two types of bone grafts were obtained from iliac crest. Twenty of the corticocancellous (CC) group underwent a wedge-shaped graft, while 14 patients of the pure cancellous (C-only) group received graft chips. In both groups, a 1.5-mm anatomically pre-contoured locking plate was used for fixation. Radiographic evaluations included the union rate and carpal alignment including scapholunate angle (SLA), radiolunate angle (RLA), intrascaphoid angle (ISA) and scaphoid height to length ratio (HLR). Clinical assessments encompassed wrist range-of-motion, grip strength, and patient-reported outcomes. RESULTS: Nineteen of the 20 patients in the CC group and 12 of the 14 patients in the C-only group respectively, achieving osseous union. The mean follow-up period in CC group was 14.7 (range, 12 ∼ 24) months and that in C-only group was 12.6 (range, 12 ∼ 15) months. Postoperatively, there were no significant intergroup differences of radiographic parameters including SLA (CC; 49.9° ± 6.7° vs. C-only; 48.9° ± 3.5°, P = 0.676), RLA (1.7° ± 6.4° vs. 2.4° ± 3.3°, P = 0.74), ISA (36° ± 7.5° vs. 36.6° ± 12.2°, P = 0.881), and HLR (0.54 ± 0.09 vs. 0.53 ± 0.05, P = 0.587). Clinical outcomes, including the flexion-extension arc (137° ± 30° vs. 158° ± 33°, P = 0.122), grip strength (93.4 % ± 15.4% vs. 99.5 % ± 16.7 %, P = 0.39), Quick Disabilities of the Arm, Shoulder, and Hand scores (11.2 ± 8.3 vs. 12.5 ± 7.7, P = 0.74) and Mayo Wrist Scores (81.2 ± 13.1 vs. 89 ± 11.4, P = 0.242) also showed no significant intergroup differences. CONCLUSIONS: Volar locking-plate fixation with pure cancellous bone grafts achieved outcomes comparable to those achieved with corticocancellous bone grafts in scaphoid nonunion with deformity, possibly due to the biomechanical advantages of the volar plate to provide structural supports.


Subject(s)
Bone Plates , Bone Transplantation , Cancellous Bone , Fracture Fixation, Internal , Fractures, Ununited , Joint Instability , Range of Motion, Articular , Scaphoid Bone , Humans , Scaphoid Bone/surgery , Scaphoid Bone/injuries , Scaphoid Bone/diagnostic imaging , Male , Female , Fractures, Ununited/surgery , Fractures, Ununited/physiopathology , Retrospective Studies , Adult , Bone Transplantation/methods , Cancellous Bone/transplantation , Fracture Fixation, Internal/methods , Joint Instability/surgery , Joint Instability/physiopathology , Treatment Outcome , Young Adult , Wrist Joint/surgery , Wrist Joint/physiopathology , Wrist Joint/diagnostic imaging , Hand Strength , Ilium/transplantation , Radiography , Fracture Healing/physiology , Adolescent , Middle Aged
4.
Eur J Orthop Surg Traumatol ; 34(4): 2171-2177, 2024 May.
Article in English | MEDLINE | ID: mdl-38570341

ABSTRACT

OBJECTIVES: Treatment of 5th metatarsal fractures via direct discharge from virtual fracture clinic (VFC) has become common practice in the NHS. We aim to assess the functional outcome and incidence of non-union in a series of 5th metatarsal base fractures, exposed to 1-year of follow-up. METHODS: 194 patients who sustained a fracture between the period February 2019 to April 2020 were included, referred via the VFC pathway. Radiographs were reviewed to classify in which zone, the fracture occurred along with union on subsequent follow-up. Telephone follow-up was used to measure patient functional outcomes (EQ-5D & FAAM survey) and satisfaction with the VFC service. RESULTS: Off 194 patients, 53 (27.3%) had zone 1, 99 (51%) had zone 2, and 42 (21.6%) had zone 3 fractures. 80 were discharged directly from VFC, with 114 patients being offered at least one face to face clinic follow-up. Six (3.1%) patients had clinical and radiological evidence of non-union; 4 in zone 2, and 2 in zone 3. No zone 1 injuries were identified as a non-union. Only 2 patients had surgery, 1 of which was for symptomatic non-union. Of the 6 non-union patients, 1 had surgery, 4 did not wish to have surgery and the final non-union patient was deemed unsuitable for surgery. CONCLUSION: The VFC is an effective way of managing 5th metatarsal fractures, with high patient satisfaction. Conservative management has excellent outcomes, with a low percentage of zone 2 and 3 injuries developing a symptomatic non-union. Functional outcome surveys provide further reassurance.


Subject(s)
Fractures, Bone , Fractures, Ununited , Metatarsal Bones , Humans , Metatarsal Bones/injuries , Metatarsal Bones/diagnostic imaging , Fractures, Ununited/surgery , Male , Female , Fractures, Bone/surgery , Adult , Middle Aged , Patient Satisfaction , Aged , Fracture Healing , Young Adult , Radiography , Retrospective Studies , Treatment Outcome
5.
Acta Orthop Belg ; 90(1): 102-109, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38669658

ABSTRACT

In 2020, the most common treatment for presumed aseptic non-union of the humeral shaft seems to be decortication, often associated with bone autografting, and stabilized by a screw plate. We propose to evaluate an original technique of rigid osteosynthesis combining intramedullary nailing and screw plate. Between January 2004 and January 2020, 45 patients underwent treatment of presumed aseptic non-union of the humeral shaft by osteosynthesis combining intramedullary nailing and a screw plate. The minimum radio-clinical follow-up was one year postoperatively. The series included 19 men and 26 women with a mean age of 53 years (range 19-84 years). Bone consolidation was achieved in 43 patients, a rate of 95.5%. Comparing patients who achieved bone consolidation with the two failed consolidations did not reveal any statistically significant factor. Interobserver agreement was almost perfect (k=0.93) for the use of the RUST for humeral shaft fractures treated with intramedullary nailing and screw plate. In our study, the treatment of presumed aseptic non- union of the humeral shaft with an osteosynthesis combining intramedullary nailing and screw plate gives, with 95.5% of bone consolidation, results equal to or even superior to the different treatments currently described in the literature.


Subject(s)
Bone Plates , Bone Screws , Fracture Fixation, Intramedullary , Fractures, Ununited , Humeral Fractures , Humans , Middle Aged , Male , Adult , Female , Fracture Fixation, Intramedullary/instrumentation , Fracture Fixation, Intramedullary/methods , Aged , Humeral Fractures/surgery , Aged, 80 and over , Fractures, Ununited/surgery , Young Adult , Retrospective Studies , Fracture Fixation, Internal/methods , Fracture Fixation, Internal/instrumentation , Fracture Healing
6.
Sci Rep ; 14(1): 7089, 2024 03 26.
Article in English | MEDLINE | ID: mdl-38528078

ABSTRACT

The purpose of this study is to evaluate the efficacy of plate augmentation and hybrid bone grafting for treating atrophic nonunion of the femur with original intramedullary nail retained in situ.In this study, 36 patients with atrophic nonunion of the femur who underwent surgery using the technique of plate augmentation and a hybrid bone grafting while retaining the original intramedullary nail in situ in Xi'an Honghui Hospital from January 2019 to December 2021 were enrolled. 28 patients who met the inclusion and exclusion criteria were ultimately included in the study. These 28 patients, consisting of 20 males and 8 females with a mean age of 38 years, were evaluated based on factors such as operation time, intraoperative blood loss, the average hospitalization days. Additionally, the results and function of these patients were evaluated by union time, Wu's scores of limb function and incidence of serious complications.All 28 patients achieved bone union at the 12 month follow-up, with an average follow-up time of 14.6 ± 4.2 months.The average operation time was 68.3 ± 11.2 min, and the average intraoperative blood loss was 140 ± 22.6 ml. Patients were hospitalized for an average of 5.8 ± 1.1 days. Full clinical and radiological bone union was achieved on average at 5.1 ± 1.9 months. The mean value of Wu's scores at the 12 month follow-up was significantly higher than before the operation. Limb function was excellent in 27 patients and good in one patient at the 12 month follow-up. However, five patients experienced the lower limb vein thrombosis, including one deep vein thrombosis and four lower limb intermuscular vein thromboses. One patient had a superficial infections of the surgical incision site, while three patients reported pain and numbness where their iliac bone graft was extracted at the 12 month follow-up. The technique of plate augmentation and hybrid bone grafting, combined with retaining the original intramedullary nail in situ has been shown to be a safe, effective, simply and standardizable practice for treating atrophic femoral nonunion with an intact original IMN fixation.


Subject(s)
Fracture Fixation, Intramedullary , Fractures, Ununited , Male , Female , Humans , Adult , Bone Transplantation/methods , Blood Loss, Surgical , Fracture Fixation, Intramedullary/methods , Bone Nails/adverse effects , Fractures, Ununited/surgery , Treatment Outcome , Femur/surgery , Lower Extremity , Retrospective Studies , Fracture Healing
7.
Arch Orthop Trauma Surg ; 144(5): 1917-1924, 2024 May.
Article in English | MEDLINE | ID: mdl-38492065

ABSTRACT

INTRODUCTION: Rib fractures commonly occur in trauma patients with varying presentations. Though the literature in recent years has moved toward favoring more early intervention of acute rib fractures, little has been reported on the matter of surgical fixation for symptomatic rib fracture nonunions. MATERIALS AND METHODS: We performed a review of PubMed and Cochrane databases for articles published since 2000. Inclusion criteria were studies with greater than six months of follow-up, while case studies were excluded. A thorough analysis was performed on patient outcomes, complications reported, operative techniques utilized, and fixation systems used, among other parameters reported by the articles. RESULTS: One hundred and thirty-nine studies resulted from our review, and a total of nine studies met our inclusion criteria with a combined total of 182 patients who underwent open reduction and internal fixation for symptomatic rib fracture nonunions. All studies reported a significant reduction of pain with increased satisfaction in the majority of patients. There were a total of 71 postoperative complications, the most common of which included surgical site infections, hardware failure, and hematoma. The most serious complications were insulting injury to the lung parenchyma or pleura; however, these were extremely rare based off the current literature. The use of bone grafting was common with eight of the nine studies mentioning the benefits of grafting. CONCLUSION: Surgical stabilization of rib fracture nonunions appears to be an appropriate treatment alternative, and various techniques and approaches may be used with similar success. Further studies with higher level of evidence are recommended on the subject.


Subject(s)
Fracture Fixation, Internal , Fractures, Ununited , Rib Fractures , Humans , Rib Fractures/surgery , Fractures, Ununited/surgery , Fracture Fixation, Internal/methods , Postoperative Complications/epidemiology , Bone Transplantation/methods
8.
J Pediatr Orthop ; 44(5): e426-e432, 2024.
Article in English | MEDLINE | ID: mdl-38454784

ABSTRACT

OBJECTIVE: This work aimed to evaluate the results of using a 2-stage surgical treatment strategy without doing anterior transposition of the ulnar nerve (ATUN) for cases with long-standing nonunited fracture lateral humeral condyle (LHC) in children, accompanied by a critical review. METHODS: A consecutive 12 children with a long-standing ">2 years" nonunited LHC with evident radiologic gross anatomic distortion of the elbow were included in this study. A 2-stage surgical treatment strategy was applied, wherein the first stage, open functional reduction, osteosynthesis, and iliac bone graft were done. Then after 6 months, the second stage surgery was carried out in the form of supracondylar humeral corrective osteotomy if the cubitus valgus angle was ≥20 degrees. ATUN was not done for any of the cases even with those having ulnar nerve dysfunction. RESULTS: Union took place in 11 out of the 12 cases after a mean follow-up period of 11 weeks (range: 8 to 14 wk; SD: 1.6). All the 7 cases showed preoperative ulnar nerve dysfunction and reported clinical recovery at the end of their follow-up. CONCLUSIONS: Two-stage surgical treatment strategy without ATUN is a convenient, reproducible, and successful line of treatment for children presented with longstanding nonunited LHC with anatomically distorted elbow. LEVEL OF EVIDENCE: Level IV-case series.


Subject(s)
Elbow Joint , Fractures, Ununited , Humeral Fractures , Child , Humans , Humeral Fractures/diagnostic imaging , Humeral Fractures/surgery , Humeral Fractures/complications , Humerus/surgery , Ulnar Nerve , Fracture Fixation, Internal/methods , Fractures, Ununited/surgery , Elbow Joint/surgery , Treatment Outcome , Range of Motion, Articular/physiology , Retrospective Studies
9.
J Orthop Trauma ; 38(6): 201-206, 2024 Jun 01.
Article in English | MEDLINE | ID: mdl-38470150

ABSTRACT

OBJECTIVES: To assess trends in Patient-Reported Outcome Measurement Information Systems (PROMIS) Physical Function (PF) and Pain Interference (PI) in surgically treated tibial shaft fracture patients progressing to union versus nonunion. DESIGN: Retrospective cohort study. SETTING: Level 1 trauma center. PATIENT SELECTION CRITERIA: Patients with operatively treated tibial shaft fractures (AO/OTA 42-A, B, C) using an intramedullary nail. OUTCOME MEASURES AND COMPARISONS: PROMIS PF and PI were compared between patients progressing to union and patients requiring nonunion repair. RESULTS: A total of 234 patients (196 union, 38 nonunion) were included consisting 144 men and 90 women. The mean age of included patients was 40.8 years. A significant difference in mean PROMIS PF between union and nonunion patients was observed at 1-3 months ( P = 0.005), 3-6 months ( P < 0.001), 6-9 months ( P = 0.003), and 6-12 months ( P = 0.018). The odds of developing nonunion for every unit decrease in PROMIS PF was significant at 3-6 months (OR 1.07, P = 0.028) and 6-9 months (OR 1.17, P = 0.015). A significant difference in mean PROMIS PI between union and nonunion patients was observed at 1-3 months ( P = 0.001), 3-6 months ( P = 0.005), and 6-9 months ( P = 0.005). The odds of developing nonunion for every unit increase in PROMIS PI was significant at 1-3 months (OR 1.11, P = 0.005), 3-6 months (OR 1.10, P = 0.011), and 6-9 months (OR 1.23, P = 0.011). CONCLUSIONS: Poorly trending PROMIS PF and PI in the clinical setting is a factor that can be used to evaluate progression to nonunion following tibial shaft repair where imaging studies may lag behind. LEVEL OF EVIDENCE: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Fracture Fixation, Intramedullary , Fractures, Ununited , Patient Reported Outcome Measures , Tibial Fractures , Humans , Tibial Fractures/surgery , Fracture Fixation, Intramedullary/methods , Fracture Fixation, Intramedullary/adverse effects , Female , Male , Adult , Fractures, Ununited/surgery , Retrospective Studies , Middle Aged , Pain Measurement , Fracture Healing , Cohort Studies
10.
Injury ; 55(6): 111462, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38490849

ABSTRACT

INTRODUCTION: The subtrochanteric region is known for its unique biomechanical properties that contribute to challenges in fracture reduction. To ensure optimal fracture healing, achieving robust mechanical stability is essential. There are very few studies in the literature describing the treatment of subtrochanteric fracture nonunion. PURPOSE: To analyze the outcomes of two techniques of revision fixation of nonunion in subtrochanteric femur fracture, namely, nail-plate fixation and plate-structural fibula graft fixation. METHODS: This was a retrospective analysis of subtrochanteric femur nonunion between January 2011 and December 2019. The demographic details, details of the index surgery, details of the revision surgery and the time to final union were collected. The nonunion was divided based on the level of the fracture into high subtrochanteric and low subtrochanteric. Two revision techniques were used: plate-structural fibula graft for high subtrochanteric and nail-plate construct for low subtrochanteric femur fractures RESULTS: Out of the 54 patients that were included, there was malalignment in 53.70 %, medial comminution in 46.3 %, distraction at the fracture site in 44.4 %, lateral trochanteric wall break in 37.03 % and implant failure in 70.37 % of the patients. There were 20 high subtrochanteric and 34 low subtrochanteric fractures. Union was achieved in 53 patients (98.14 %). The mean LEFS score was 71.4 in the nail-plate group and 66.2 in the plate-structural fibula graft group (p 0.003). CONCLUSION: The treatment of subtrochanteric femur fracture nonunion can be a daunting task. The goal is to correct the varus and restore the medial support which will prevent the occurrence of collapse and another failure. We were able to achieve this with both the nail-plate and the plate- structural fibula graft revision methods.


Subject(s)
Bone Nails , Bone Plates , Fibula , Fracture Healing , Fractures, Ununited , Hip Fractures , Humans , Male , Female , Retrospective Studies , Fibula/transplantation , Fibula/injuries , Fractures, Ununited/surgery , Middle Aged , Fracture Healing/physiology , Adult , Hip Fractures/surgery , Fracture Fixation, Internal/methods , Fracture Fixation, Internal/instrumentation , Bone Transplantation/methods , Treatment Outcome , Reoperation , Fracture Fixation, Intramedullary/methods , Fracture Fixation, Intramedullary/instrumentation , Aged
11.
Bone Joint J ; 106-B(4): 387-393, 2024 Apr 01.
Article in English | MEDLINE | ID: mdl-38555933

ABSTRACT

Aims: There is a lack of published evidence relating to the rate of nonunion seen in occult scaphoid fractures, diagnosed only after MRI. This study reports the rate of delayed union and nonunion in a cohort of patients with MRI-detected acute scaphoid fractures. Methods: This multicentre cohort study at eight centres in the UK included all patients with an acute scaphoid fracture diagnosed on MRI having presented acutely following wrist trauma with normal radiographs. Data were gathered retrospectively for a minimum of 12 months at each centre. The primary outcome measures were the rate of acute surgery, delayed union, and nonunion. Results: A total of 1,989 patients underwent acute MRI for a suspected scaphoid fracture during the study period, of which 256 patients (12.9%) were diagnosed with a previously occult scaphoid fracture. Of the patients with scaphoid fractures, six underwent early surgical fixation (2.3%) and there was a total of 16 cases of delayed or nonunion (6.3%) in the remaining 250 patients treated with cast immobilization. Of the nine nonunions (3.5%), seven underwent surgery (2.7%), one opted for non-surgical treatment, and one failed to attend follow-up. Of the seven delayed unions (2.7%), one (0.4%) was treated with surgery at two months, one (0.4%) did not attend further follow-up, and the remaining five fractures (1.9%) healed after further cast immobilization. All fractures treated with surgery had united at follow-up. There was one complication of surgery (prominent screw requiring removal). Conclusion: MRI-detected scaphoid fractures are not universally benign, with delayed or nonunion of scaphoid fractures diagnosed only after MRI seen in over 6% despite appropriate initial immobilization, with most of these patients with nonunion requiring surgery to achieve union. This study adds weight to the evidence base supporting the use of early MRI for these patients.


Subject(s)
Fractures, Bone , Fractures, Closed , Fractures, Ununited , Hand Injuries , Scaphoid Bone , Wrist Injuries , Humans , Fractures, Bone/surgery , Retrospective Studies , Cohort Studies , Scaphoid Bone/injuries , Wrist Injuries/diagnostic imaging , Wrist Injuries/surgery , Fracture Fixation, Internal/adverse effects , Fractures, Closed/diagnostic imaging , Fractures, Closed/etiology , Magnetic Resonance Imaging , Hand Injuries/complications , Fractures, Ununited/diagnostic imaging , Fractures, Ununited/surgery , Fractures, Ununited/complications
12.
Arch Orthop Trauma Surg ; 144(3): 1259-1268, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38372763

ABSTRACT

INTRODUCTION: Intramedullary (IM) nailing is the treatment of choice for femoral shaft fractures, but nonunion rates have been reported to be as high as 12%. Surgical interventions for nonunion involve exchange nailing or plate augmentation. Recently, a combined treatment of exchange nailing and plate augmentation has demonstrated good results, but its comparative effectiveness remains unclear. This study aimed to compare the clinical and radiographic outcomes of three different surgical interventions for atrophic femoral shaft nonunion, and investigate the factors that affect bone healing after reoperation. MATERIALS AND METHODS: A retrospective study was conducted at five university hospitals involving 149 patients with aseptic atrophic nonunion after IM nailing. These patients underwent reoperation with plate augmentation, exchange nailing, or combined treatment. Clinical and radiographic outcomes were assessed and compared according to reoperation procedure. Logistic regression analysis was performed to identify factors affecting persistent nonunion after reoperation. RESULTS: Of the cohort, 57 patients underwent plate augmentation, 64 underwent exchange nailing, and 28 received combined treatment. There were no significant differences in patient demographics among the groups. Exchange nailing produced a significantly lower union rate than did the combined treatment (82.8% vs. 100%, p = 0.016), whereas no significant difference was observed in the union rate and time to the union between plate augmentation and the combined treatment. Combined treatment showed the longest operative time and the greatest transfusion requirements. The risk factors for persistent nonunion included age, absence of autogenous bone grafts, and use of an exchange nailing technique. CONCLUSIONS: Exchange nailing as a treatment for atrophic femoral shaft nonunion after IM nailing resulted in a lower union rate. The efficacy of the combined treatment requires further study, and persistent nonunion may be influenced by age, bone grafting, and surgical techniques. A comprehensive approach targeting both biological environment and mechanical stability is crucial in the treatment of atrophic femoral shaft nonunion.


Subject(s)
Femoral Fractures , Fracture Fixation, Intramedullary , Fractures, Ununited , Humans , Fracture Fixation, Intramedullary/adverse effects , Retrospective Studies , Treatment Outcome , Bone Nails/adverse effects , Fractures, Ununited/surgery , Fractures, Ununited/etiology , Femoral Fractures/surgery , Femoral Fractures/etiology , Fracture Healing
13.
In Vivo ; 38(2): 611-619, 2024.
Article in English | MEDLINE | ID: mdl-38418118

ABSTRACT

BACKGROUND/AIM: Effective treatment of nonunion fractures is challenging as it requires a biological and mechanical environment to promote sufficient osteogenesis. Herein, we present a case series in which we evaluated the clinical efficacy of bone morphogenetic protein-2 (BMP-2)-loaded alginate microbeads and allografts in two dogs with nonunion fractures. CASE REPORT: A 3-year-old, 2.3-kg, spayed female Pomeranian (Case 1) presented with intermittent lameness of the left forelimb after radial and ulnar fracture repair 8 weeks prior. A 4-year-old, 4.8-kg, spayed female Pomeranian (Case 2) was referred for non-weight-bearing lameness of the left hindlimb due to implant failure following left tibial fracture repair. Both dogs had atrophic bone ends and no bridging calluses at the fracture site on radiographs, and were diagnosed with nonviable nonunion fractures of the radius/ulna and tibia, respectively. The surgical approach involved implant removal, debridement, and fracture gap reconstruction. BMP-2 was loaded into alginate microbeads for a prolonged release with bone allograft chips in both cases. In Case 1, bead grafts were applied directly at the fracture site, while in Case 2, they were implanted inside a frozen cortical bone allograft as a scaffold to fill the large gap. Postoperative radiography revealed excessive callus formation, early radiographic bone union, and cortical bone remodeling, in line with improved lameness scores. At the final follow-up, gait was improved and the desired bone length and shape were achieved in both cases. CONCLUSION: Simultaneous use of osteoinductive BMP-2 alginate microbeads and osteoconductive bone allografts yielded functionally and structurally favorable outcomes in canine nonunion fractures, without major complications.


Subject(s)
Fractures, Bone , Fractures, Ununited , Dogs , Animals , Female , Microspheres , Alginates , Lameness, Animal , Fractures, Ununited/surgery , Allografts , Fracture Healing
14.
Hand Surg Rehabil ; 43(2): 101662, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38354948

ABSTRACT

To assess factors related to health-system and patient behavior in scaphoid fracture non-union, a retrospective analysis of 134 patients treated by scaphoid reconstruction was performed. Mean age at the accident was 26 years (range, 9-75 years), and the mean age at surgery was 28 years (range, 13-75 years). Mean time to first consultation was 233 days (range, 0-12,136 days), and time to surgery 740 days (range, 19-12,362 days). The physician was mainly a general practitioner (52.2%), or an orthopedist/traumatologist (17.9%), general surgeon (12.7%), or hand surgeon (17.2%). The initial diagnostic procedure was X-ray in 76.9% of cases, computed tomography (CT) in 20.9%, magnetic resonance imaging (MRI) in 13.4%, and none in 11.2%. A fracture was diagnosed in 32.8% of cases, and non-union in 14.9%. Patients mainly presented late: 63% within 3 weeks, and a minority on the day of the accident (39%). In 11% of cases, healthcare providers performed either no or inadequate imaging (77%) and missed correct diagnosis in 52% of cases. 128 patients had a second consultation, and 77 a third, with the same or different physicians, before surgery, leading to increased healthcare costs due to delayed diagnosis and treatment. Delayed presentation and lack of suspicion by attending physicians were the main reasons. Speeding up diagnosis and improving physician training are vital and could significantly reduce health care costs. CT or MRI should be performed if scaphoid fracture is suspected.


Subject(s)
Fractures, Ununited , Scaphoid Bone , Humans , Scaphoid Bone/injuries , Scaphoid Bone/diagnostic imaging , Scaphoid Bone/surgery , Adult , Adolescent , Middle Aged , Fractures, Ununited/surgery , Fractures, Ununited/diagnostic imaging , Retrospective Studies , Male , Female , Young Adult , Aged , Child , Tomography, X-Ray Computed , Magnetic Resonance Imaging , Time-to-Treatment , Practice Patterns, Physicians'/statistics & numerical data
15.
Musculoskelet Surg ; 108(2): 125-132, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38340306

ABSTRACT

The purpose of the study was to investigate whether arthroscopic treatment of carpal scaphoid nonunions by osteosynthesis with bone grafting represents a successful surgical technique. This systematic literature review, conducted following the PRISMA guidelines, explores the past 10 years of clinical studies concerning the arthroscopic treatment of scaphoid nonunions. The most relevant keywords were used to search the databases, and the Downs and Black 27-item checklist has been used as quality assessment tool. Twelve papers that meet the premised eligibility criteria have been identified. These studies demonstrate the efficacy of this surgical solution, achieving a postoperative union rate of 96% in the average time of 13.5 weeks. Regardless of the method of synthesis and the origin of the graft used, excellent results were obtained. Patients who underwent this procedure reported a pain reduction of almost 80% compared to the preoperative level, improvement in grip strength close to 40%, and recovery in wrist function during daily activities. Arthroscopy has numerous advantages compared to the open approach. These are technically recognized by the surgeon and by the patient. Some disadvantages include a longer intraoperative time and considerable significant technical difficulty. Arthroscopic treatment of scaphoid nonunion by osteosynthesis with bone graft achieves a 96% union rate of the treated scaphoid with satisfying clinical results.


Subject(s)
Arthroscopy , Bone Transplantation , Fractures, Ununited , Scaphoid Bone , Humans , Scaphoid Bone/injuries , Scaphoid Bone/surgery , Arthroscopy/methods , Fractures, Ununited/surgery , Bone Transplantation/methods , Fracture Fixation, Internal/methods , Treatment Outcome , Hand Strength
16.
JBJS Case Connect ; 14(1)2024 Jan 01.
Article in English | MEDLINE | ID: mdl-38335298

ABSTRACT

CASE: A 15-year-old female rock climber presented with a traumatic coracoid process fracture of her dominant upper extremity that failed extensive nonoperative treatment. She was treated successfully by arthroscopic reduction and suture anchor fixation. CONCLUSION: A novel surgical technique for coracoid fracture that combines arthroscopic reduction with suture anchor fixation can result in expeditious and durable clinical improvement in a young, high-demand athlete.


Subject(s)
Fractures, Bone , Fractures, Ununited , Female , Humans , Adolescent , Suture Anchors , Arthroscopy/methods , Fractures, Bone/surgery , Fracture Fixation, Internal/methods , Fractures, Ununited/diagnostic imaging , Fractures, Ununited/surgery , Upper Extremity
17.
Injury ; 55(3): 111412, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38341997

ABSTRACT

INTRODUCTION: Our primary aim of the study was to assess the results of a treatment protocol for aseptic femoral shaft nonunion treated by three techniques - Exchange Nailing (EN), Plate Augmentation (PA), and Exchange Nailing combined with Plate augmentation (NP). The secondary objective was to assess the radiological outcome, duration of surgery (DOS) and need for blood transfusion (BT) in all the three groups. MATERIALS AND METHODS: We analyzed 330 patients treated for AFNU between Jan 2007 and Dec 2019. Using a simple treatment algorithm, EN, PA and NP were performed in 24,183 and 123 patients respectively. Patients in all the three groups were assessed for radiological-union (union rate and time to union), DOS and BT. RESULTS: Of these 330 patients, 327 (99 %) patients achieved radiological union at a mean duration of 6.07 months. Union rate is highest with NP followed by PA and EN. The union rate in patients with NP, PA and EN were 100 %, 99.5 % and 91.7 % respectively (p < 0.01). Time to union was lowest for NP followed by PA and EN (p < 0.001).The mean time to union for NP, PA and EN were 3.76, 7.2and 9.21 months respectively (p < 0.001). The mean DOS in minutes for NP, EN and PA was 107, 94 and 82 respectively (p < 0.01). The mean need for BT in the form of packed red blood cells for NP, PA and EN were 1.95, 1.87 and 1.38 units respectively (p < 0.01). CONCLUSION: Following a simple algorithm to decide treatment protocol on a case-to case basis helps to achieve good results in an optimal time period. When compared with EN and PA, NP is associated with 100 % union rate with least time to union making NP a reasonably effective procedure with a very high success rate. LEVEL OF EVIDENCE: IV.


Subject(s)
Femoral Fractures , Fracture Fixation, Intramedullary , Fractures, Ununited , Humans , Fracture Fixation, Intramedullary/methods , Treatment Outcome , Femoral Fractures/diagnostic imaging , Femoral Fractures/surgery , Femoral Fractures/etiology , Fractures, Ununited/surgery , Fractures, Ununited/etiology , Bone Nails/adverse effects , Bone Plates , Clinical Protocols , Retrospective Studies
18.
J Foot Ankle Surg ; 63(3): 411-413, 2024.
Article in English | MEDLINE | ID: mdl-38346585

ABSTRACT

Injury to the tarsometatarsal joint (TMT) results in instability throughout the midfoot that does not often improve with conservative management. If instability is identified, surgical intervention is frequently recommended, either open reduction and internal fixation (ORIF) or primary arthrodesis (PA). These 2 treatment options have been compared in the literature multiple times, often reporting similar outcomes. Due to this, as well as the need for subsequent hardware removal after ORIF has led many surgeons towards PA at the index surgery. Concern for nonunion is a leading concern with surgeons who advocate instead for ORIF. The purpose of this study is to review patients who underwent PA and observe nonunion rates. Nonunion at the TMT has been previously studied, but only in the chronic setting. We performed a retrospective study of 34 patients who had PA in the management of an acute Lisfranc injury. The average age in our study was 43.9 years old (range 19-72, SD 17.4) with an average follow-up of 9.4 months (range 4-33, SD 6.2). Radiographs were evaluated for signs of nonunion at regular postoperative intervals. Within the patients included in the study, a total of 71 TMT joints were fused. Overall successful fusion rate was 95.8% at an average of 7.9 weeks (range 6-12, SD 1.4) postoperatively. Individual nonunion rates at the first, second, and third TMT were 0%, 1.4% and 2.8% respectively. Our study demonstrates that primary arthrodesis provides a predictable outcome with low nonunion rates in the management of acute Lisfranc injury.


Subject(s)
Arthrodesis , Fractures, Ununited , Humans , Arthrodesis/methods , Retrospective Studies , Adult , Middle Aged , Male , Female , Aged , Fractures, Ununited/surgery , Fractures, Ununited/diagnostic imaging , Young Adult , Fracture Fixation, Internal/methods , Metatarsal Bones/injuries , Metatarsal Bones/surgery , Tarsal Joints/surgery , Tarsal Joints/injuries , Treatment Outcome , Foot Injuries/surgery , Foot Injuries/diagnostic imaging , Follow-Up Studies , Foot Joints/surgery , Foot Joints/injuries , Foot Joints/diagnostic imaging , Radiography
19.
BMC Musculoskelet Disord ; 25(1): 20, 2024 Jan 02.
Article in English | MEDLINE | ID: mdl-38167040

ABSTRACT

BACKGROUND: Corticocancellous bone grafting from the iliac crest is acceptable treatment for unstable scaphoid nonunion with a viable proximal pole. However, harvesting graft from the iliac crest is associated with donor site morbidity and the requirement of general anesthesia. Thus, bone grafting from the anterolateral metaphysis of the distal radius (DR) can be a treatment option. However, no study has compared the clinical effect between the two grafting techniques. METHODS: From 2014 to 2019, patients with unstable scaphoid nonunion with humpback deformity underwent corticocancellous bone grafting from the anterolateral metaphysis of the DR (group DR) or iliac crest (group IC). Humpback deformity was determined by evaluating the scapholunate angle (SLA) ≥ 60°, intrascaphoid angle (ISA) ≥ 45°, and radiolunate angle (RLA) ≥ 15° from preoperative radiographs and computed tomography scans. The SLA, ISA, and RLA served to gauge carpal alignment. The operative time, grip strength, active range of motion (ROM), the Modified Mayo Wrist score (MMWS), and Disabilities of Arm, Shoulder, and Hand (DASH) score were assessed postoperatively. RESULTS: Thirty-eight patients qualified for the study (group DR, 15; group IC, 23). Union rates did not differ by patient subset (group DR, 100%; group IC, 95.7%; P = .827), and grip strength, ROM, MWS, and DASH score were similar between groups at the last follow-up. The operative time (minutes) was significantly shorter in group DR (median, 98; quartiles, 80, 114) than in group IC (median, 125; quartiles, 105, 150, P < .001). The ISA, RLA, and SLA improved postoperatively in both groups (P < 0.001). The degree of restoring carpal alignment, as evaluated by SLA, showed superior correction capability in group DR (median, 25.3% quartiles, 21.1, 35.3, P < 0.05). Donor site complications were not significantly different between the groups. CONCLUSIONS: Corticocancellous bone graft from the anterolateral metaphysis of the DR for unstable scaphoid nonunion is associated with a shorter operation time and comparable results with that from the iliac crest in regard to union, restoration of carpal alignment, and wrist function. LEVEL OF EVIDENCE: Level III.


Subject(s)
Fractures, Ununited , Scaphoid Bone , Humans , Radius/diagnostic imaging , Radius/surgery , Bone Transplantation/methods , Ilium/transplantation , Fractures, Ununited/diagnostic imaging , Fractures, Ununited/surgery , Scaphoid Bone/diagnostic imaging , Scaphoid Bone/surgery , Fracture Fixation, Internal/methods , Retrospective Studies
20.
JBJS Case Connect ; 14(1)2024 Jan 01.
Article in English | MEDLINE | ID: mdl-38207082

ABSTRACT

CASE: An 18-year-old autistic boy with seizure disorder had a 4-month-old hip injury with a similar right hip injury 6 months earlier. X-rays revealed an ununited fracture neck femur on the left and a malunited fracture neck femur on the right hip. Magnetic resonance imaging indicated preserved head vascularity. Valgus osteotomy and double-angle plate fixation of both hips were performed at an interval of 2 months. CONCLUSION: Delayed presentation bilateral neck fractures are rare. X-rays showed healed fractures with no avascular necrosis in both hips at 2-year 6-month follow-up. Valgus osteotomy is ideal and relevant for osteosynthesis in selected ununited femur neck fractures.


Subject(s)
Autistic Disorder , Femoral Neck Fractures , Fractures, Ununited , Adolescent , Humans , Male , Femoral Neck Fractures/complications , Femoral Neck Fractures/diagnostic imaging , Femoral Neck Fractures/surgery , Femur Neck , Fractures, Ununited/surgery , Osteotomy/methods
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