Subject(s)
Blastomycosis/diagnosis , Fungemia/diagnosis , Skin Diseases, Vesiculobullous/diagnosis , Aged , Amphotericin B/therapeutic use , Antifungal Agents/therapeutic use , Biopsy, Needle , Blastomycosis/drug therapy , Blastomycosis/ethnology , Canada , Diagnosis, Differential , Fever/diagnosis , Fever/etiology , Follow-Up Studies , Fungemia/drug therapy , Fungemia/ethnology , Humans , Immunohistochemistry , Low Back Pain/diagnosis , Low Back Pain/etiology , Male , Native Hawaiian or Other Pacific Islander , Rare Diseases , Skin Diseases, Vesiculobullous/pathology , Treatment OutcomeABSTRACT
A total of 108 cases of candidemia detected in 3 tertiary care university hospitals in Hawaii between January 2001 and December 2002 were retrospectively reviewed. Candida albicans, Candida glabrata, and Candida tropicalis accounted for 28% of the cases. Mortality among Filipino patients was significantly higher than that among other ethnic groups (71% vs 48%; P<.05).
Subject(s)
Candida/classification , Candidiasis/ethnology , Candidiasis/epidemiology , Fungemia/ethnology , Fungemia/epidemiology , Hospitals, University , Adult , Aged , Aged, 80 and over , Candida/isolation & purification , Candida albicans/isolation & purification , Candida glabrata/isolation & purification , Candida tropicalis/isolation & purification , Candidiasis/microbiology , Candidiasis/mortality , Female , Fungemia/microbiology , Fungemia/mortality , Hawaii/epidemiology , Hawaii/ethnology , Humans , Male , Middle Aged , Risk FactorsABSTRACT
The authors describe three cases of Histoplasma capsulatum histoplasmosis that occurred in black AIDS patients living in France but originally from Guinea and Ivory Coast. In all three cases histoplasmosis was disseminated with fever. In two cases there were cutaneous manifestations. One patient had renal insufficiency and nephrotic syndrome and another presented ulcerative colitis with histoplasma in the chorion. The outcome was favorable in two patients. These three cases are in addition to the five previously reported cases in african AIDS patients. These cases stress the need for awareness of this opportunistic infection as a complication of AIDS in patients from Black Africa.