ABSTRACT
OBJECTIVE: Report of clinical and microbiological periodontal findings before and 6 months after treatment of two siblings with Papillon-Lefèvre syndrome (PLS) and tinea capitis. METHODS: Two brothers, RG 3 years and NG 5 years of age, were referred for treatment due to premature mobility of their deciduous teeth. Probing depths (PPD), attachment levels (PAL-V), and furcation involvements were examined clinically. Panoramic radiographs were taken. Subgingival plaque samples within the deepest pocket of each tooth were taken and analysed by real-time polymerase chain reaction (PCR) for Actinobacillus actinomycetemcomitans (AA), Porphyromonas gingivalis, Tannerella forsythensis, Treponema denticola, Fusobacterium nucleatum, and Prevotella intermedia. One-stage full-mouth scaling and extraction of hopeless teeth were performed under general anaesthesia, followed by systemic amoxicillin and metronidazole for 7 days. Clinical and microbiological analyses were performed 6 months after treatment. RESULTS: Before treatment, both siblings had exhibited PPD of up to 13 mm, Class III furcation defects at four teeth, and marginal suppuration. AA was detected in both patients and at all teeth at levels ranging from 3.0 x 10(2) to 5.1 x 10(6). Both patients exhibited palmar and plantar hyperkeratosis. Seven teeth were extracted from RG, and nine from NG. Six months after treatment, PPD had been reduced to Subject(s)
Papillon-Lefevre Disease/genetics
, Periodontal Diseases/genetics
, Tinea Capitis/genetics
, Aggregatibacter actinomycetemcomitans/isolation & purification
, Amoxicillin/therapeutic use
, Anti-Bacterial Agents/therapeutic use
, Anti-Infective Agents/therapeutic use
, Child, Preschool
, Dental Plaque/microbiology
, Dental Scaling
, Follow-Up Studies
, Furcation Defects/genetics
, Furcation Defects/therapy
, Humans
, Male
, Metronidazole/therapeutic use
, Periodontal Attachment Loss/genetics
, Periodontal Attachment Loss/therapy
, Periodontal Diseases/therapy
, Periodontal Pocket/genetics
, Periodontal Pocket/therapy
, Tooth Extraction
, Tooth Mobility/genetics
, Tooth Mobility/therapy
, Tooth, Deciduous/pathology
ABSTRACT
This case report demonstrates the simultaneous development of furcation bone loss in three-rooted tooth #30 with vital pulp tissue in identical twins. In the first report, resolution of furcal bone loss was seen after nonsurgical root canal treatment. In the second report, furcal bone loss resolved after non-surgical root canal treatment, and periodontal therapy reduced probing depths to maintainable levels.
