Subject(s)
Athletic Injuries/microbiology , Bacterial Translocation , Fusobacterium Infections/microbiology , Fusobacterium nucleatum/isolation & purification , Lumbar Vertebrae/injuries , Meningitis, Bacterial/microbiology , Spinal Fractures/complications , Anti-Infective Agents/therapeutic use , Bacteremia/drug therapy , Bacteremia/etiology , Bacteremia/microbiology , Bacterial Typing Techniques/methods , Colon/microbiology , Culture Media , Diabetes Mellitus, Type 2/complications , Diagnosis, Differential , Dura Mater/injuries , False Negative Reactions , Fusobacterium Infections/cerebrospinal fluid , Fusobacterium Infections/drug therapy , Fusobacterium Infections/etiology , Fusobacterium nucleatum/growth & development , Humans , Leukocytosis/cerebrospinal fluid , Leukocytosis/etiology , Low Back Pain/etiology , Male , Meningitis, Bacterial/cerebrospinal fluid , Meningitis, Bacterial/drug therapy , Meningitis, Bacterial/etiology , Metronidazole/therapeutic use , Middle Aged , Off-Road Motor Vehicles , Psoas Abscess/microbiology , Wound Infection/diagnosisABSTRACT
This paper reports a case of fatal meningitis caused by Fusobacterium necrophorum subsp. necrophorum in a previously healthy five-year-old child. The organism was isolated in pure culture from the cerebrospinal fluid and from intracranial pus obtained at autopsy. The role of F. necrophorum in the development of meningitis is reaffirmed and its isolation and identification are discussed. The clinical presentation of the present case resembles the previously published reports and highlights the poor prognosis in spite of appropriate antibiotic treatment.
Subject(s)
Fusobacterium Infections/microbiology , Fusobacterium necrophorum/isolation & purification , Meningitis, Bacterial/microbiology , Child, Preschool , Female , Fusobacterium Infections/cerebrospinal fluid , Humans , Meningitis, Bacterial/cerebrospinal fluid , Species SpecificityABSTRACT
Central nervous system (CNS) infection caused by anaerobic bacteria (including Bacteroides, Fusobacterium, Peptostreptococcus, and Eubacterium) was diagnosed in two dogs and two cats. In one dog there was extensive meningomyeloencephalitis, presumably the result of hematogenous spread of bacteria from lung abscesses and bacterial endocarditis. Subdural empyema of unknown origin was found in a second dog and two cats. Clinical signs in all four animals included mental depression and focal neurologic deficits, without fever.
