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1.
J Comp Pathol ; 175: 69-74, 2020 Feb.
Article in English | MEDLINE | ID: mdl-32138845

ABSTRACT

Body wall defects (BWDs) are not well studied and categorized in veterinary medicine. BWDs can be an isolated occurrence, but often occur with other major developmental abnormalities. Thirty-two body wall malformations of domestic pigs (Sus scrofa domesticus) are presented and classified, distinguishing between body wall dysplasia (umbilical hernia, abdominal wall distension and gastroschisis), omphalocoele and thoracoabdominoschisis (Cantrell syndrome, shistosomus reflexus, body stalk anomalies).


Subject(s)
Gastroschisis/veterinary , Hernia, Umbilical/veterinary , Sus scrofa/abnormalities , Animals , Female , Male , Swine
2.
Reprod Domest Anim ; 55(5): 652-655, 2020 May.
Article in English | MEDLINE | ID: mdl-32003081

ABSTRACT

This report describes multiple congenital malformations found in three dog litters delivered by emergency caesarean section. In all of the litters, some puppies were born alive but were euthanized because of the seriousness of their malformations and low probability of survival. In two litters, gastroschisis was associated with amelia of the right anterior limb. Other malformations such as anencephaly were also found in three puppies among the different litters. This report describes the morphological findings of the affected puppies, discusses the most appropriate terminologies for each case and highlights the importance of an epidemiological survey to identify potential factors associated with the cases.


Subject(s)
Abnormalities, Multiple/veterinary , Dog Diseases/congenital , Anencephaly/veterinary , Animals , Animals, Newborn , Cesarean Section/veterinary , Dogs , Ectromelia/veterinary , Female , Gastroschisis/veterinary , Pregnancy
3.
Comp Med ; 63(4): 342-7, 2013 Aug.
Article in English | MEDLINE | ID: mdl-24209970

ABSTRACT

Congenital malformations may occur during early embryogenesis in cases of genetic abnormalities or various environmental factors. Affected subjects most often have only one or 2 abnormalities; subjects rarely have several unrelated congenital defects. Here we describe a case of a stillborn New Zealand white rabbit with multiple complex congenital malformations, including synophthalmia, holoprosencephaly, gastroschisis, and a supernumerary hindlimb, among other anomalies. There was no historical exposure to teratogens or other known environmental causes. Although not confirmed, this case was most likely a rare spontaneous genetic event.


Subject(s)
Abnormalities, Multiple/veterinary , Rabbits/abnormalities , Abnormalities, Multiple/pathology , Animals , Gastroschisis/pathology , Gastroschisis/veterinary , Holoprosencephaly/pathology , Holoprosencephaly/veterinary , Limb Deformities, Congenital/pathology , Limb Deformities, Congenital/veterinary , Stillbirth/veterinary
4.
Anat Histol Embryol ; 37(3): 192-5, 2008 Jun.
Article in English | MEDLINE | ID: mdl-18162096

ABSTRACT

Congenital malformations correspond to one of the main causes of embryonic loss during the gestational process. They result from interaction of several factors such as multifactor heredity, chromosomal and genetic alterations and environmental agents; however, unknown aetiology also can be present. In this article, we have used 10 embryos, from a frigorific area of Dracena, SP, Brazil, which were fixed in Bouin solution for a macro- and micro-scopic description. We could verify the presence of an encephalic tissue mass on the embryo's dorsal cranial area, resulting from the non-formation of part of the cranial cap and from the non-closing of cephalic neuropore and consequent neuroepithelial cells disorganization. In the abdominal area, the embryos did not show the complete fusion of the body lateral pleats during the abdominal wall formation, and the liver extruded into the amniotic cavity without involvement of the intestine.


Subject(s)
Anencephaly/veterinary , Cattle/abnormalities , Cattle/embryology , Gastroschisis/veterinary , Anencephaly/ultrastructure , Animals , Female , Gastroschisis/ultrastructure , Pregnancy
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