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Am J Trop Med Hyg ; 95(4): 868-870, 2016 Oct 05.
Article in English | MEDLINE | ID: mdl-27402520

ABSTRACT

Gnathostomiasis is a zoonotic disease endemic in Asia. It most commonly manifests as gastrointestinal and cutaneous disease. Central nervous system involvement is a rare but feared complication, often leaving patients with permanent neurologic deficits. Clinicians outside of Asia and Latin America may have little experience with this illness, causing delays in diagnosis and treatment. We describe a 40-year-old woman who developed a progressive myelopathy over 18 months. She had never traveled outside of New Zealand. Cerebrospinal fluid (CSF) showed marked eosinophilia and Gnathostoma serology was positive in both serum and CSF. This is the first report of gnathostomiasis acquired in New Zealand, and the first case of neurognathostomiasis reported outside Asia. Clinicians should include neurognathostomiasis in the differential diagnosis of myelopathy and CSF eosinophilia, even if there is no history of travel to endemic areas.


Subject(s)
Gnathostomiasis/diagnostic imaging , Myelitis/diagnostic imaging , Spinal Cord Diseases/physiopathology , Adult , Eosinophilia/cerebrospinal fluid , Female , Gnathostomiasis/cerebrospinal fluid , Gnathostomiasis/complications , Humans , Magnetic Resonance Imaging , Myelitis/cerebrospinal fluid , Myelitis/complications , New Zealand , Spinal Cord Diseases/etiology , Thoracic Vertebrae
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