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1.
J Burn Care Res ; 42(3): 434-438, 2021 05 07.
Article in English | MEDLINE | ID: mdl-33022715

ABSTRACT

Treadmill burns that occur from friction mechanism are a common cause of hand burns in children. These burns are deeper and more likely to require surgical intervention compared to hand burns from other mechanisms. The purpose of this study was to identify the factors associated with healing time using an initial nonoperative approach. A retrospective chart review was performed examining children (<15 years) who were treated for treadmill burns to the hand between 2012 and 2019. Patient age, burn depth, total body surface area of the hand injury, and time to healing were recorded. Topical wound management strategies (silver sheet, silver cream, non-silver sheet, and non-silver cream) and associated treatment durations were determined. For patients with burns to bilateral hands, the features, treatment, and outcomes of each hand were assessed separately. Cox regression analysis was used to evaluate the association between time to healing and patient characteristics and treatment type. Seventy-seven patients with 86 hand burns (median age 3 years, range 1-11) had a median total body surface area per hand burn of 0.8% (range 0.1-1.5%). Full-thickness burns (n = 47, 54.7%) were associated with longer time to healing compared to partial-thickness burns (HR 0.28, CI 0.15-0.54, P < .001). Silver sheet treatment was also associated with more rapid time to healing compared to treatment with a silver cream (HR 2.64, CI 1.01-6.89, P = .047). Most pediatric treadmill burns can be managed successfully with a nonoperative approach. More research is needed to confirm the superiority of treatment with silver sheets compared to treatment with silver creams.


Subject(s)
Anti-Infective Agents, Local/therapeutic use , Burns/drug therapy , Burns/etiology , Hand Injuries/drug therapy , Hand Injuries/etiology , Sports Equipment/adverse effects , Administration, Topical , Bandages , Child , Child, Preschool , Female , Friction , Humans , Infant , Male , Phenols , Retrospective Studies , Silver Sulfadiazine/therapeutic use , Wound Healing
2.
J Emerg Nurs ; 47(1): 28-32, 2021 Jan.
Article in English | MEDLINE | ID: mdl-33183770

ABSTRACT

Hydrofluoric acid is a caustic compound found in a wide variety of items for household and industrial uses. Dermal exposures can be visually unimpressive on presentation but still have fatal complications. This case review includes a description of a patient presenting with a dermal hydrofluoric acid burn that was effectively treated with topical calcium gluconate gel. Also highlighted are the challenges faced with recognizing the severity and appropriately treating dermal hydrofluoric acid burns in the emergency department.


Subject(s)
Burns, Chemical/drug therapy , Burns, Chemical/etiology , Calcium Gluconate/administration & dosage , Hand Injuries/chemically induced , Hand Injuries/drug therapy , Hydrofluoric Acid/toxicity , Administration, Topical , Adult , Emergency Service, Hospital , Gels , Humans , Male
5.
Rev Soc Bras Med Trop ; 52: e20190055, 2019 May 30.
Article in English | MEDLINE | ID: mdl-31166489

ABSTRACT

Snakebites by aglyphous or opisthoglyphous snakes are common in Brazil. We report a case of snakebite by the opisthoglyphous Erythrolamprus aesculapii. The victim presented with pain, edema, and bleeding at the bite site, along with erythema, similar to a Bothrops envenomation. In this type of snakebite, if the snake is not brought to the hospital, the victim may receive unnecessary serum therapy, with the risk of adverse reactions to the antivenom. The possibility of reducing after-effects with anti-inflammatory drugs and early antibiotic therapy for secondary infection need to be further investigated, preferably in multicenter studies, while observing good clinical practice.


Subject(s)
Colubridae , Hand Injuries/etiology , Snake Bites/complications , Snake Venoms/poisoning , Accidents, Occupational , Animals , Betamethasone/therapeutic use , Brazil , Hand Injuries/drug therapy , Histamine Antagonists/therapeutic use , Humans , Male , Snake Bites/drug therapy , Young Adult
6.
Unfallchirurg ; 122(4): 323-327, 2019 Apr.
Article in German | MEDLINE | ID: mdl-30498896

ABSTRACT

Burns and thermal injuries from other causes often affect exposed body regions such as the hands. Besides aesthetic aspects, deep dermal burns of the skin are often critical from a functional point of view, especially for important subcutaneous structures. This article reports the course of two patients who received enzymatic debridement with bromelain-based salve as a treatment for deep grade burns of the hands.


Subject(s)
Bromelains/administration & dosage , Burns/drug therapy , Burns/surgery , Debridement/methods , Dermatologic Agents/administration & dosage , Hand Injuries/drug therapy , Burns/complications , Hand Injuries/surgery , Humans , Ointments/administration & dosage , Skin/drug effects , Skin Transplantation , Wound Healing/drug effects
7.
Rev. Soc. Bras. Med. Trop ; 52: e20190055, 2019. graf
Article in English | LILACS | ID: biblio-1013312

ABSTRACT

Abstract Snakebites by aglyphous or opisthoglyphous snakes are common in Brazil. We report a case of snakebite by the opisthoglyphous Erythrolamprus aesculapii. The victim presented with pain, edema, and bleeding at the bite site, along with erythema, similar to a Bothrops envenomation. In this type of snakebite, if the snake is not brought to the hospital, the victim may receive unnecessary serum therapy, with the risk of adverse reactions to the antivenom. The possibility of reducing after-effects with anti-inflammatory drugs and early antibiotic therapy for secondary infection need to be further investigated, preferably in multicenter studies, while observing good clinical practice.


Subject(s)
Humans , Animals , Male , Young Adult , Snake Bites/complications , Snake Venoms/poisoning , Colubridae , Hand Injuries/etiology , Snake Bites/drug therapy , Brazil , Betamethasone/therapeutic use , Accidents, Occupational , Hand Injuries/drug therapy , Histamine Antagonists/therapeutic use
9.
Benef Microbes ; 7(5): 631-637, 2016 Nov 30.
Article in English | MEDLINE | ID: mdl-27633174

ABSTRACT

Probiotic treatment has been shown to improve bone formation, increase bone mass density and prevent bone loss. We aimed to assess the effect of probiotic treatment on functional recovery in elderly patients with a distal radius fracture. A total of 417 elderly patients with an acute distal radius fracture were enrolled in this double-blind placebo-controlled clinical trial. They were randomised to receive skimmed milk containing either a commercial probiotic (Lactobacillus casei Shirota) or placebo daily for a period of 6 months after the fracture. Treatment outcomes were the DASH (disabilities of the arm, shoulder and hand) score, pain, complex regional pain syndrome (CRPS) score, active range of motion and grip strength, all of which were measured on a monthly basis. Throughout the duration of the study, DASH score, pain, CRPS score, wrist flexion and grip strength of patients receiving probiotics exhibited a significantly faster pace of improvement than those on placebo, with treatment outcomes of patients receiving Lactobacillus casei Shirota at month 4 at comparable levels with those of patients receiving placebo at month 6. In elderly patients with a fracture of the distal radius, administration of the probiotic could greatly accelerating the healing process.


Subject(s)
Complex Regional Pain Syndromes/drug therapy , Lacticaseibacillus casei , Probiotics/administration & dosage , Radius Fractures/drug therapy , Aged , Arm Injuries/drug therapy , Double-Blind Method , Female , Hand Injuries/drug therapy , Humans , Male , Middle Aged , Prospective Studies , Range of Motion, Articular/drug effects , Recovery of Function/drug effects , Shoulder Injuries/drug therapy , Treatment Outcome
11.
J Orthop Res ; 34(1): 154-60, 2016 Jan.
Article in English | MEDLINE | ID: mdl-26177854

ABSTRACT

The purpose of the study was to test a novel treatment that carbodiimide-derivatized-hyaluronic acid-lubricin (cd-HA-lubricin) combined cell-based therapy in an immobilized flexor tendon repair in a canine model. Seventy-eight flexor tendons from 39 dogs were transected. One tendon was treated with cd-HA-lubricin plus an interpositional graft of 8 × 10(5) BMSCs and GDF-5. The other tendon was repaired without treatment. After 21 day of immobilization, 19 dogs were sacrificed; the remaining 20 dogs underwent a 21-day rehabilitation protocol before euthanasia. The work of flexion, tendon gliding resistance, and adhesion score in treated tendons were significantly less than the untreated tendons (p < 0.05). The failure strength of the untreated tendons was higher than the treated tendons at 21 and 42 days (p < 0.05). However, there is no significant difference in stiffness between two groups at day 42. Histologic analysis of treated tendons showed a smooth surface and viable transplanted cells 42 days after the repair, whereas untreated tendons showed severe adhesion formation around the repair site. The combination of lubricant and cell treatment resulted in significantly improved digit function, reduced adhesion formation. This novel treatment can address the unmet needs of patients who are unable to commence an early mobilization protocol after flexor tendon repair.


Subject(s)
Bone Marrow Transplantation , Glycoproteins/therapeutic use , Growth Differentiation Factor 5/therapeutic use , Hand Injuries/surgery , Hyaluronic Acid/analogs & derivatives , Tendon Injuries/surgery , Animals , Dogs , Drug Evaluation, Preclinical , Hand Injuries/drug therapy , Hyaluronic Acid/therapeutic use , Random Allocation , Tendon Injuries/drug therapy , Transplantation, Autologous
12.
G Ital Med Lav Ergon ; 36(1): 22-4, 2014.
Article in Italian | MEDLINE | ID: mdl-24665624

ABSTRACT

The broad market penetration of products with components used primarily in the industrial sector requires the precise knowledge of their mechanism of action in order to perform a correct therapeutic approach. The article reports on three cases of domestic hydrofluoric acid burn that came to our Plastic Surgery Unit over the last three years. The treatment options are discussed in detail with emphasis on the importance of a constant update about such emerging diseases.


Subject(s)
Accidents, Home , Burns, Chemical/etiology , Burns, Chemical/therapy , Calcium Gluconate/therapeutic use , Hand Injuries/chemically induced , Hand Injuries/therapy , Hydrofluoric Acid/adverse effects , Administration, Cutaneous , Adult , Burns, Chemical/diagnosis , Burns, Chemical/drug therapy , Burns, Chemical/surgery , Calcium Gluconate/administration & dosage , Emergencies , Female , Finger Injuries/chemically induced , Finger Injuries/therapy , Follow-Up Studies , Gels/administration & dosage , Hand Injuries/diagnosis , Hand Injuries/drug therapy , Hand Injuries/surgery , Humans , Male , Middle Aged , Plastic Surgery Procedures/methods , Surgery, Plastic , Treatment Outcome
13.
Am J Orthop (Belle Mead NJ) ; 42(8): 379-82, 2013 Aug.
Article in English | MEDLINE | ID: mdl-24078958

ABSTRACT

High-pressure injection injuries often have a misleadingly benign presentation. However, it is important to recognize the potential surgical urgency and long-term sequelae associated with these injuries. We present a case of paint gun injection to the palm and review the literature on high-pressure paint injection injuries. The 3 factors most important for the fate of the limb are material type, injection pressure, and injury site. The immediate use of antibiotics and tetanus prophylaxis, with or without steroids, is indicated. Urgent debridement in the operating room is imperative and can decompress the neurovascular structures and flexor tendon sheath by removing the irritating agents. Reported overall amputation rates have been as high as 30%.


Subject(s)
Hand Injuries/therapy , Occupational Injuries/therapy , Paint , Wounds, Penetrating/therapy , Adult , Anti-Bacterial Agents/therapeutic use , Debridement , Hand Injuries/drug therapy , Hand Injuries/surgery , Humans , Male , Occupational Injuries/drug therapy , Occupational Injuries/surgery , Treatment Outcome , Wounds, Penetrating/drug therapy , Wounds, Penetrating/surgery
14.
Ann Vasc Surg ; 27(8): 1183.e5-10, 2013 Nov.
Article in English | MEDLINE | ID: mdl-23988538

ABSTRACT

Ulnar artery thrombosis and hypothenar hammer syndrome are rare vascular complications that could potentially occur with repeated blows or trauma to the hand. Although initially reported as an occupational hazard among laborers and craftsmen, it has been observed more recently among recreationalists and athletes. Until now, it has never been reported as a complication in ice hockey players. In this case report, a 26-year-old Canadian professional ice hockey player presented with acute dominant right hand paleness, coolness, and pain with hand use. The patient used a wooden hockey stick with a large knob of tape at the end of the handle, which he regularly gripped in the palm of his right hand to help with face-offs and general stick-handling. Sonographic evaluation demonstrated no arterial flow in the distal right ulnar artery distribution, and ulnar artery occlusion with no aneurysmal degeneration was confirmed by magnetic resonance angiogram. Intraarterial thrombolytic therapy was initiated, and subsequent serial angiograms demonstrated significant improvement in distal ulnar artery flow as well as recanalization of right hand deep palmar arch and digital arteries. The patient's symptoms resolved, and he was maintained on therapeutic anticoagulation for 3 months prior to returning to playing ice hockey professionally, but with a padded glove and no tape knob at the handle tip. This case highlights a unique presentation of hockey stick-handling causing ulnar artery thrombosis that was likely from repeated palmar hypothenar trauma. Appropriate diagnostic imaging, early intraarterial thrombolysis, and postoperative surveillance and follow-up were crucial for the successful outcome in this patient.


Subject(s)
Arterial Occlusive Diseases/etiology , Cumulative Trauma Disorders/etiology , Hand Injuries/etiology , Hand/blood supply , Hockey/injuries , Ischemia/etiology , Sports Equipment/adverse effects , Thrombosis/etiology , Ulnar Artery , Adult , Anticoagulants/therapeutic use , Arterial Occlusive Diseases/diagnosis , Arterial Occlusive Diseases/drug therapy , Arterial Occlusive Diseases/physiopathology , Constriction, Pathologic , Cumulative Trauma Disorders/diagnosis , Cumulative Trauma Disorders/drug therapy , Cumulative Trauma Disorders/physiopathology , Hand Injuries/diagnosis , Hand Injuries/drug therapy , Hand Injuries/physiopathology , Humans , Ischemia/diagnosis , Ischemia/drug therapy , Ischemia/physiopathology , Magnetic Resonance Angiography , Male , Radiography , Recovery of Function , Regional Blood Flow , Syndrome , Thrombolytic Therapy , Thrombosis/diagnosis , Thrombosis/drug therapy , Thrombosis/physiopathology , Time Factors , Treatment Outcome , Ulnar Artery/diagnostic imaging , Ulnar Artery/physiopathology , Ultrasonography
19.
J Surg Orthop Adv ; 22(4): 256-62, 2013.
Article in English | MEDLINE | ID: mdl-24393182

ABSTRACT

The purpose of this study is to report the percentage of patients achieving union, time to union, and complications with the use of bone morphogenetic protein-2 (rh-BMP-2) in surgical repair of established nonunion in the hand and wrist. Twenty-seven patients with nonunion of the hand and wrist were treated between 2005 and 2011 with surgical repair and augmentation using 4.2 mg of rh-BMP-2. Sites of nonunion included the phalanx (seven), carpus (nine), distal radius (five), and distal ulna (six). Radiographic union and complications were the primary and secondary outcomes, respectively. Eighty-nine percent (24/27) of patients achieved union within an average of 4.3 ± 2.8 months of surgery. There were no direct complications from administration of rh-BMP-2. Radiographic union was consistent with published rates for nonunion repair of scaphoid, phalanx, and distal radius fractures. Rh-BMP-2 did not produce superior rates of union in the patients with wrist and hand nonunion.


Subject(s)
Bone Morphogenetic Protein 2/therapeutic use , Fractures, Ununited/drug therapy , Hand Injuries/drug therapy , Wrist Injuries/drug therapy , Adolescent , Adult , Female , Fractures, Ununited/surgery , Hand Injuries/surgery , Humans , Male , Middle Aged , Recombinant Proteins/therapeutic use , Retrospective Studies , Treatment Outcome , Wrist Injuries/surgery , Young Adult
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