ABSTRACT
ABSTRACT We developed a pre-clinical model in which to evaluate the impact of orally administered carbohydrates on postprandial blood glucose levels. For this purpose, we compared the effects of different carbohydrates with well-established glycemic indexes. We orally administered (gavage) increasing amounts (0.2, 0.4, 0.6, 0.8, and 1.0 g/kg) of sucrose and lactose to rats which had been fasted for 6 h or 15 h, respectively. In part of the experiments we administered frutose (gavagem). Three different models were compared for measuring postprandial blood glucose levels: a) evaluation of interstitial glucose concentrations by using a real time continuous glucose monitoring system; b) evaluation of glucose levels in blood obtained from the rat tail; c) evaluation of serum glucose levels in blood collected after decapitation. Our results showed that blood obtained from the tails of 15-h fasted rats was the best model in which to evaluate the effect of carbohydrates on postprandial blood glucose levels.
Subject(s)
Animals , Male , Rats , Administration, Oral , Glycemic Index/genetics , Health Impact Assessment/instrumentation , Carbohydrates/analysis , Glycemic Load/drug effectsABSTRACT
OBJECTIVE: Hurricane Sandy in the Rockaways, Queens, forced residents to evacuate and primary care providers to close or curtail operations. A large deficit in primary care access was apparent in the immediate aftermath of the storm. Our objective was to build a computational model to aid responders in planning to situate primary care services in a disaster-affected area. METHODS: Using an agent-based modeling platform, HAZEL, we simulated the Rockaways population, its evacuation behavior, and primary care providers' availability in the aftermath of Hurricane Sandy. Data sources for this model included post-storm and community health surveys from New York City, a survey of the Rockaways primary care providers, and research literature. The model then tested geospatially specific interventions to address storm-related access deficits. RESULTS: The model revealed that areas of high primary care access deficit were concentrated in the eastern part of the Rockaways. Placing mobile health clinics in the most populous census tracts reduced the access deficit significantly, whereas increasing providers' capacity by 50% reduced the deficit to a lesser degree. CONCLUSIONS: An agent-based model may be a useful tool to have in place so that policy makers can conduct scenario-based analyses to plan interventions optimally in the event of a disaster. (Disaster Med Public Health Preparedness. 2016;10:386-393).
Subject(s)
Cyclonic Storms , Health Impact Assessment/methods , Health Services Accessibility/statistics & numerical data , Primary Health Care/statistics & numerical data , Computer Simulation , Health Impact Assessment/instrumentation , Health Services Accessibility/standards , Humans , New York CityABSTRACT
Objetivo. Conocer los impactos en salud percibidos por vecinos y agentes sociales como consecuencia de dos intervenciones de regeneración urbana (nueva lonja de pescado y reordenación de La Herrera Norte/Oeste) en la bahía de Pasaia (Gipuzkoa, España) que han sido objeto de una evaluación del impacto en salud (EIS). Método. Metodología cualitativa. Muestreo teórico e intencional. Generación de información mediante 18 entrevistas personales y cinco grupos de discusión. Análisis conforme al modelo de análisis sociológico del discurso. Triangulación y contraste de los resultados preliminares entre miembros del equipo y participantes del estudio. Resultados. Se identifican cuatro áreas interrelacionadas de impacto en salud: calidad urbana, conectividad, cohesión social y, en menor grado, empleo. Se señalan los aspectos concretos de mejora a tener en cuenta en cada ámbito, así como la influencia del contexto sociopolítico y las concepciones sobre la salud. Las repercusiones del proceso de ejecución de las obras y las diferentes perspectivas según los roles y perfiles sociales de los participantes constituyen hallazgos asimismo importantes. Conclusiones. El conocimiento de las percepciones y expectativas de los afectados mediante los métodos cualitativos aporta elementos e interrelaciones novedosas y necesarias para la aplicación de la EIS como herramienta de mejora de la salud y de participación ciudadana (AU)
Aim. To determine the health impact perceived by residents and social players involved in two urban regeneration interventions (a new fish market and the redevelopment of North/West Herrera) in Pasaia Bay (Gipuzkoa, Spain) that have been the subject of a health impact assessment (HIA). Method. Qualitative methodology was used with theoretical and intentional sampling. Information was obtained through 18 personal interviews and five discussion groups and was analyzed in accordance with the sociological analysis model of discourse. The preliminary results were triangulated and contrasted among the team members and those taking part in the study. Results. Four interrelated areas of health impact were identified: urban quality, connectivity, social cohesion, and-to a lesser extent-employment. Specific aspects for improvement were indicated for each field, as well as the influence of the sociopolitical context and conceptions of health. Other significant findings were the impact of the process of carrying out the building work and the distinct perspectives due to the differing roles and social profiles of participants. Conclusions. Knowledge of the perceptions and expectations of affected individuals through qualitative methods provides novel elements and interrelations that are needed to apply HIA as a tool for improving health and for citizen participation (AU)
Subject(s)
Humans , Male , Female , /methods , /standards , Environment/policies , Health Impact Assessment/instrumentation , Health Impact Assessment/methods , Health Impact Assessment , Socioeconomic Factors , Social Participation , Focus Groups/methodsABSTRACT
The level of chronic illness acceptance is an indicator of functioning and predictor of quality of life. The greater the acceptance of disease is, the less mental discomfort and less severe negative emotions there are. This paper presents Acceptance of Illness Scale and the main results and conclusions of the recent publications dealing with this problem in patients with chronic diseases. It has been proved that the level of acceptance of illness is significantly associated with a variety of clinical and sociodemographic factors. This justifies the rightness of its assessment, which appears to be an important element in the holistic medical and nonmedical care.
Subject(s)
Attitude to Health , Chronic Disease/psychology , Health Impact Assessment/instrumentation , Illness Behavior , Patient Acceptance of Health Care/psychology , Quality of Life , Adaptation, Psychological , Health Impact Assessment/statistics & numerical data , Humans , Patient Acceptance of Health Care/statistics & numerical dataABSTRACT
We propose a new approach to assess the impact of traffic-related air pollution on public health by mapping personal trajectories using mobile phone tracking technology in an urban environment. Although this approach is not based on any empirical studies, we believe that this method has great potential and deserves serious attention. Mobile phone tracking technology makes it feasible to generate millions of personal trajectories and thereby cover a large fraction of an urban population. Through analysis, personal trajectories are not only associated to persons, but it can also be associated with vehicles, vehicle type, vehicle speed, vehicle emission rates, and sources of vehicle emissions. Pollution levels can be estimated by dispersion models from calculated traffic emissions. Traffic pollution exposure to individuals can be estimated based on the exposure along the individual human trajectories in the estimated pollution concentration fields by utilizing modelling tools. By data integration, one may identify trajectory patterns of particularly exposed human groups. The approach of personal trajectories may open a new paradigm in understanding urban dynamics and new perspectives in population-wide empirical public health research. This new approach can be further applied to individual commuter route planning, land use planning, urban traffic network planning, and used by authorities to formulate air pollution mitigation policies and regulations.
Subject(s)
Air Pollutants/toxicity , Cell Phone , Environmental Exposure , Health Impact Assessment/methods , Urban Health , Vehicle Emissions/toxicity , Health Impact Assessment/instrumentation , Humans , Models, TheoreticalABSTRACT
Over the past years, application of health impact assessment has increased substantially, and there has been a strong growth of tools that allow quantification of health impacts for a range of health relevant policies. We review these developments, and conclude that further tool development is no longer a main priority, although several aspects need to be further developed, such as methods to assess impacts on health inequalities and to assess uncertainties. The main new challenges are, first, to conduct a comparative evaluation of different tools, and, second, to ensure the maintenance and continued availability of the toolkits including their data contents.
