Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
Forensic Sci Int ; 208(1-3): e10-4, 2011 May 20.
Article in English | MEDLINE | ID: mdl-21377819

ABSTRACT

Virus-induced myocarditis is a common disease even in infants and young adults, but the diagnosis can be difficult according to the Dallas-criteria, which have been criticized as being too unreliable. The diagnosis has been substantially improved due to immunohistochemistry (IHC) for the detection of the VP1-capsid-protein of enterovirus as well as reversetranscriptase-polymerase chain reaction assays (RT-PCR) for viral genome detection. We report an unusual case of myocarditis in a young adult athlete whose heart disease was not clinically recognized and, thus, caused his sudden unexpected death (SUD). Histopathological investigations of heart tissue samples revealed signs of myocarditis. IHC was used to detect the VP1-capsid-protein of enterovirus. RT-PCR assays were used to detect enterovirus RNA. Enterovirus myocarditis was determined as a cause of death.


Subject(s)
Athletes , Death, Sudden/etiology , Enterovirus Infections/diagnosis , Myocarditis/diagnosis , Myocarditis/virology , Adult , Capsid Proteins/analysis , Enterovirus B, Human/genetics , Forensic Pathology , Heart Septum/pathology , Heart Septum/virology , Heart Ventricles/pathology , Heart Ventricles/virology , Humans , Immunohistochemistry , Lymphocytes/pathology , Male , Myocardium/pathology , Necrosis/pathology , RNA, Viral/genetics , Reverse Transcriptase Polymerase Chain Reaction , Tunisia , Young Adult
SELECTION OF CITATIONS
SEARCH DETAIL
...