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4.
Gastroenterol Hepatol ; 31(2): 79-81, 2008 Feb.
Article in Spanish | MEDLINE | ID: mdl-18279646

ABSTRACT

Traumatic hemobilia consists of hemorrhage into the biliary tract as a result of abdominal trauma. The classical triad of biliary colic, jaundice and upper gastrointestinal bleeding is not a constant finding, and clinically silent hemobilia has been reported. The treatment of choice is selective embolization, but spontaneous cessation of bleeding can occur, especially in mild forms. We report a case of occult traumatic hemobilia in which the diagnosis was suggested by transitory changes in ultrasonography and hepatic biochemistry.


Subject(s)
Gallbladder/injuries , Hemobilia/etiology , Seat Belts/adverse effects , Wounds, Nonpenetrating/etiology , Accidents, Traffic , Aged , Brain Concussion/etiology , Fatty Liver/complications , Gallbladder/diagnostic imaging , Gilbert Disease/blood , Gilbert Disease/complications , Hemobilia/blood , Hemobilia/diagnostic imaging , Humans , Hyperbilirubinemia/etiology , Male , Tomography, X-Ray Computed , Ultrasonography , Wounds, Nonpenetrating/blood , Wounds, Nonpenetrating/diagnostic imaging
5.
J Biomed Mater Res ; 33(3): 193-7, 1996.
Article in English | MEDLINE | ID: mdl-8864891

ABSTRACT

Poly (2-hydroxyethyl methacrylate) (PHEMA) particles of cylindrical and spherical shape were developed as a preparation for tumor treatment or control of hemorrhage by blocking their blood supply. In this report, PHEMA particles were used for the management of hemobilia, that is, bleeding into biliary passages. The origin of hemobilia in 31 patients was localized by selective angiography. With the objective of prophylaxy of hemorrhage, selective embolization with PHEMA particles of the branches of the hepatic artery responsible for the supply of blood to the focus of damage was used in 18 patients. This low-trauma method allowed either a complete control of bleeding or, at least, intraoperative blood loss was reduced more than twice. Histological investigation of the occluded blood vessels showed that the thrombus was attached to the particles and was reinforced by the porous structure of the polymer. A hypercoagulation reaction was observed in the postembolization period. This allowed correction of the hypocoagulation in the hemostasis system.


Subject(s)
Embolization, Therapeutic , Hemobilia/therapy , Polyhydroxyethyl Methacrylate , Bile Ducts, Intrahepatic/pathology , Bile Ducts, Intrahepatic/surgery , Biomarkers , Blood Coagulation , Blood Loss, Surgical , Hemobilia/blood , Hemobilia/pathology , Humans , Liver/metabolism , Liver/pathology , Male , Microspheres , Middle Aged , Neovascularization, Pathologic/pathology
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