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1.
Am Surg ; 89(7): 3292-3294, 2023 Jul.
Article in English | MEDLINE | ID: mdl-36853850

ABSTRACT

Endometriosis is a benign, inflammatory disease characterized by the presence of dysfunctional endometrial tissue outside the uterus. Typically confined to the pelvis, endometriosis is frequently associated with pain, dysmenorrhea, and infertility. Rarely, endometrial tissue has been documented to implant within the lung parenchyma and involve both parietal and visceral pleura of the thorax. Manifestations of thoracic endometriosis include catamenial pneumothorax, hemothorax, and hemoptysis. We present a case of thoracic endometriosis in a 43-year-old female who was found to have a loculated pleural effusion with an associated pleural nodule after gynecologic surgery. The patient underwent thoracotomy, decortication, and nodule excision. Pathology of the pleural nodule showed evidence of endometrial tissue within the parietal pleural. Thoracic endometriosis is a medical problem that is frequently undiagnosed and encountered by the practicing surgeon. Early diagnosis reduces both disease progression and late complications, allowing for early initiation of appropriate medical and surgical therapy.


Subject(s)
Endometriosis , Pleural Diseases , Pneumothorax , Female , Humans , Adult , Endometriosis/complications , Endometriosis/diagnosis , Endometriosis/surgery , Hemoptysis/complications , Hemoptysis/pathology , Pleural Diseases/complications , Pleural Diseases/diagnosis , Pneumothorax/etiology , Pleura
2.
Chest ; 160(4): e339-e342, 2021 10.
Article in English | MEDLINE | ID: mdl-34625180
4.
Jpn J Clin Oncol ; 51(6): 851-856, 2021 May 28.
Article in English | MEDLINE | ID: mdl-33855367

ABSTRACT

Previous reports on transarterial treatment for lung cancer were reviewed. The bronchial arterial infusion therapy has a long history since 1964. Better local control with less doses of anti-neoplastic agents was warranted by trying transarterial administration to lung and mediastinal tumors. It is reported that both primary and metastatic tumors are fed by bronchial or other systemic arteries. The bronchial arterial embolization for hemoptysis has been introduced for clinical practice since 1973. Hemoptysis by not only benign but also malignant diseases has been well controlled by embolization. In recent decades, the technical elements for transarterial treatments have markedly improved. They make it possible to carry out precise procedures of selective catheter insertion to the tumor relating arteries. Current concepts of transarterial treatment, technical aspects and treatment outcomes are summarized. Tentative result from chemo-embolization for advanced lung cancer using recent catheter techniques was also described. It provides favorable local control and survival merits. It is considered that a population of lung cancer patients can benefit from transarterial management using small doses of anti-neoplastic agents, with less complications and less medical costs.


Subject(s)
Bronchial Arteries/surgery , Embolization, Therapeutic , Lung Neoplasms/therapy , Bronchial Arteries/pathology , Catheterization, Peripheral/methods , Disease Progression , Embolization, Therapeutic/adverse effects , Embolization, Therapeutic/methods , Embolization, Therapeutic/mortality , Hemoptysis/etiology , Hemoptysis/pathology , Hemoptysis/therapy , Humans , Lung/blood supply , Lung/pathology , Lung/surgery , Lung Neoplasms/complications , Lung Neoplasms/pathology , Treatment Outcome
5.
Intern Med ; 60(5): 803-805, 2021 Mar 01.
Article in English | MEDLINE | ID: mdl-33456035

ABSTRACT

Coronavirus disease 2019 (COVID-19) is a novel infectious disease affecting the general population worldwide. A fever and cough are the common clinical presentations of COVID-19. In most of these patients, computed tomography (CT) shows bilateral peripheral ground-glass opacities. We herein report a case of hemoptysis and lung bulla in the convalescent phase of COVID-19. Based on the clinical observations, alveolar destruction was likely associated with hemoptysis and bulla formation. Therefore, we suggest the follow-up of COVID-19 patients whose clinical parameters indicate alveolar damage, even after their symptoms improve.


Subject(s)
Blister/etiology , COVID-19/complications , COVID-19/pathology , Hemoptysis/etiology , Lung/pathology , Blister/diagnostic imaging , Blister/pathology , COVID-19/diagnostic imaging , Cough/virology , Fever/virology , Hemoptysis/diagnostic imaging , Hemoptysis/pathology , Humans , Lung/diagnostic imaging , Male , Middle Aged , Pulmonary Alveoli/diagnostic imaging , Pulmonary Alveoli/pathology , SARS-CoV-2 , Tomography, X-Ray Computed
8.
Rev Mal Respir ; 37(7): 518-525, 2020 Sep.
Article in French | MEDLINE | ID: mdl-32654939

ABSTRACT

INTRODUCTION: Massive hemoptysis is a rare but serious presentation of pulmonary hydatid cysts. The literature reporting this clinical phenomenon is limited to sporadic cases. MATERIAL AND METHODS: We undertook a retrospective study considering patients who had undergone lung surgery because of hydatid cyst from January 2000 o December 2015 and examined features associated with massive hemoptysis. RESULTS: Among 270 patients operated on for lung hydatidosis, 13 (4.8%) had experienced massive hemoptysis. This sub group had an average age of 24±12 years (13-60 years) and a sex ratio of 0.85. Preoperative embolization was attempted in 5 patients but failed in all cases. All patients with massive hemoptysis were operated on emergency. The origin of bleeding was determined and controlled in all cases (from a vein or an artery from the pulmonary circulation). Pulmonary re-expansion was satisfactory after obliteration of the residual cavity and no pulmonary resection was necessary. The postoperative course was uneventful in 11 patients. Prolonged air-leak beyond 7 days was noted in two patients but settled subsequently with simple follow-up. Average postoperative follow-up was 32 months (8-63 months). One patient (who had hydatid vomit with massive hemoptysis) developed controlateral hydatid recurrence that was also successfully operated on. No recurrence of hemoptysis was noted during the follow-up period for all patients. CONCLUSION: Massive haemoptysis secondary to pulmonary hydatidosis may be life-threatening. Surgery of hydatid cysts associated with direct vascular control of eroded vessels is sufficient to control hemoptysis.


Subject(s)
Echinococcosis, Pulmonary/complications , Echinococcosis, Pulmonary/therapy , Hemoptysis/etiology , Hemoptysis/therapy , Adolescent , Adult , Diagnostic Techniques, Respiratory System , Echinococcosis, Pulmonary/diagnosis , Echinococcosis, Pulmonary/pathology , Female , Hemoptysis/diagnosis , Hemoptysis/pathology , Humans , Male , Middle Aged , Pneumonectomy/methods , Retrospective Studies , Severity of Illness Index , Thoracic Surgical Procedures/methods , Young Adult
9.
Med Clin North Am ; 104(3): 455-470, 2020 May.
Article in English | MEDLINE | ID: mdl-32312409

ABSTRACT

Respiratory symptoms are common in patients living with serious illness, both in cancer and nonmalignant conditions. Common symptoms include dyspnea (breathlessness), cough, malignant pleural effusions, airway secretions, and hemoptysis. Basic management of respiratory symptoms is within the scope of primary palliative care. There are pharmacologic and nonpharmacologic approaches to treating respiratory symptoms. This article provides clinicians with treatment approaches to these burdensome symptoms.


Subject(s)
Cough/therapy , Critical Illness/therapy , Dyspnea/therapy , Hemoptysis/therapy , Pleural Effusion, Malignant/drug therapy , Analgesics, Opioid/administration & dosage , Analgesics, Opioid/adverse effects , Analgesics, Opioid/therapeutic use , Bodily Secretions/drug effects , Combined Modality Therapy/methods , Cough/epidemiology , Cough/etiology , Cough/pathology , Dyspnea/epidemiology , Dyspnea/etiology , Dyspnea/pathology , Hemoptysis/epidemiology , Hemoptysis/etiology , Hemoptysis/pathology , Humans , Mortality/trends , Palliative Care/standards , Pleural Effusion, Malignant/epidemiology , Pleural Effusion, Malignant/mortality , Prevalence , Respiratory System/drug effects , Respiratory System/physiopathology , Risk Factors
10.
Kobe J Med Sci ; 65(4): E114-E117, 2020 Jan 20.
Article in English | MEDLINE | ID: mdl-32201425

ABSTRACT

Pulmonary lymphangioleiomyomatosis accounts for the majority of cadaveric lung transplantation cases. Post-transplantation management is continuingly necessary not only to prevent the progression of LAM but also to address complications. A woman with lymphangioleiomyomatosis underwent cadaveric lung transplantation. She developed post-operative native lung hyperinflation and hemoptysis with cavity shadow in the native lung on computed tomography. Isolated Aspergillus from her sputum and positive Aspergillus galactomannan antigen in the blood led to a diagnosis of aspergillosis. Despite the reduction of hemoptysis by antifungal medication, she developed fatal hemoptysis. An autopsy showed an Aspergillus fungal mass in the bronchus in the native lung whilst the lung graft was free from lymphangioleiomyomatosis lesions. Endobronchial aspergilloma was suggested to be a cause of hemoptysis. This fatal clinical course suggested that hemoptysis due to endobronchial aspergilloma in the native lung should have been considered native lung pneumonectomy as a further intervention.


Subject(s)
Bronchi/microbiology , Hemoptysis/etiology , Lung Neoplasms/surgery , Lung Transplantation/adverse effects , Lymphangioleiomyomatosis/surgery , Pulmonary Aspergillosis/complications , Fatal Outcome , Female , Hemoptysis/pathology , Humans , Lung Neoplasms/pathology , Lymphangioleiomyomatosis/pathology , Middle Aged , Pulmonary Aspergillosis/pathology
11.
Respiration ; 99(5): 431-440, 2020.
Article in English | MEDLINE | ID: mdl-31935732

ABSTRACT

Hemoptysis is a frequently encountered symptom in many clinical settings, and etiologic diagnosis can sometimes prove challenging. Bronchoscopy may not promptly reveal the source or the cause of bleeding and few reports have focused so far on the abnormalities of bronchial mucosa vasculature that may unveil the underlying pathophysiology. In this special feature article, we present a series of cases presenting with hemoptysis after angiographic interventions in the thoracic vessels. Localized hyperemia and vascular dilatations in the bronchial mucosa observed during bronchoscopy as unique findings became clues enabling the correct diagnosis and management. We suggest the relevant pathophysiological mechanisms and discuss the available published experience on similar clinical entities.


Subject(s)
Aneurysm/diagnostic imaging , Bronchi/blood supply , Hemoptysis/pathology , Hyperemia/pathology , Postoperative Complications/pathology , Pulmonary Artery/diagnostic imaging , Pulmonary Veins/pathology , Varicose Veins/pathology , Aneurysm/etiology , Aneurysm/surgery , Atrial Fibrillation/surgery , Autoimmune Diseases , Behcet Syndrome/complications , Behcet Syndrome/diagnosis , Bronchial Arteries/surgery , Bronchoscopy , Catheter Ablation/adverse effects , Endovascular Procedures/adverse effects , Female , Hemoptysis/diagnostic imaging , Hemoptysis/etiology , Humans , Hyperemia/diagnostic imaging , Hyperemia/etiology , Iatrogenic Disease , Lung , Male , Middle Aged , Postoperative Complications/diagnostic imaging , Postoperative Complications/etiology , Pulmonary Veins/diagnostic imaging , Thoracic Surgery, Video-Assisted , Varicose Veins/etiology , Young Adult
13.
J Vet Intern Med ; 33(6): 2718-2724, 2019 Nov.
Article in English | MEDLINE | ID: mdl-31663636

ABSTRACT

An 8-year-old 24.6 kg mixed breed dog underwent bronchoscopy for evaluation of a persistent progressive cough. Bronchoscopy documented a markedly thick and irregular, cobblestone appearance of the mucosa. A bronchoscopic biopsy was obtained; immediately after the biopsy, a large amount of hemorrhage poured from the endotracheal tube. Multiple efforts to control the hemorrhage were unsuccessful and the dog suffered a cardiopulmonary arrest and could not be revived. A necropsy was performed, which was significant for pallor, evidence of prior heartworm disease, prominent bronchial arteries, and erosion of the submucosal vessels at the site of the biopsy. The cause of death was hemorrhage associated with transbronchial biopsy of an enlarged bronchial artery associated with heartworm disease. This report describes a rare complication of a routine diagnostic procedure.


Subject(s)
Bronchoscopy/veterinary , Dog Diseases/etiology , Hemoptysis/veterinary , Animals , Biopsy/adverse effects , Biopsy/veterinary , Bronchoscopy/adverse effects , Dog Diseases/pathology , Dogs , Fatal Outcome , Hemoptysis/etiology , Hemoptysis/pathology , Male , Respiratory Mucosa/pathology
15.
J Int Med Res ; 47(4): 1766-1770, 2019 Apr.
Article in English | MEDLINE | ID: mdl-30871394

ABSTRACT

Pulmonary endometriosis is a rare form of thoracic endometriosis. We herein describe a 29-year-old woman with recurrent hemoptysis associated with her menstrual cycle. The patient had a 4-month history of catamenial hemoptysis without thoracic pain, respiratory embarrassment, cough, fever, night sweating, or loss of appetite. Chest computed tomography revealed exudation shadows in the right lower pulmonary lobe and small fiber lesions in the right middle lobe and left lung. Thoracoscopic wedge resection of the right lower pulmonary lobe was performed, and the pathological result was pulmonary endometriosis. No evidence of hemoptysis during menstruation was found following the operation.


Subject(s)
Endometriosis/pathology , Hemoptysis/pathology , Adult , Endometriosis/complications , Endometriosis/surgery , Female , Hemoptysis/complications , Hemoptysis/surgery , Humans , Menstruation , Prognosis , Thoracic Surgery, Video-Assisted
17.
Respir Res ; 20(1): 23, 2019 Jan 31.
Article in English | MEDLINE | ID: mdl-30704502

ABSTRACT

BACKGROUND: To determine the clinical role, safety, and diagnostic accuracy of percutaneous transthoracic needle biopsy in the evaluation of pulmonary consolidation. METHODS: A retrospective review of all computed tomography (CT)-guided percutaneous transthoracic needle biopsies (PTNB) at a tertiary care hospital over a 4-year period was performed to identify all cases of PTNB performed for pulmonary consolidation. For each case, CT Chest images were reviewed by two thoracic radiologists. Histopathologic and microbiologic results were obtained and clinical follow-up was performed. RESULTS: Thirty of 1090 (M:F 17:30, mean age 67 years) patients underwent PTNB for pulmonary consolidation (2.8% of all biopsies). A final diagnosis was confirmed in 29 patients through surgical resection, microbiology, or clinicoradiologic follow-up for at least 18 months after biopsy. PTNB had an overall diagnostic accuracy of 83%. A final diagnosis of malignancy was made in 20/29 patients, of which 19 were correctly diagnosed by PTNB, resulting in a sensitivity of 95% and specificity of 100% for malignancy. In all cases of primary lung cancer, adequate tissue for molecular testing was obtained. A benign final diagnosis was made in 9 patients, infection in 5 cases and non-infectious benign etiology in 4 cases. PTNB correctly diagnosed all cases of infection. Minor complications occurred in 13% (4/30) of patients. CONCLUSIONS: Pulmonary consolidation can be safely evaluated with CT-guided percutaneous needle biopsy. Diagnostic yield is high, especially for malignancy. PTNB of pulmonary consolidation should be considered following non-diagnostic bronchoscopy.


Subject(s)
Biopsy, Needle/methods , Image-Guided Biopsy/methods , Lung Diseases/diagnosis , Lung/pathology , Respiratory Tract Infections/diagnosis , Aged , Aged, 80 and over , Biopsy, Needle/adverse effects , Female , Hemoptysis/diagnosis , Hemoptysis/pathology , Humans , Image Processing, Computer-Assisted , Image-Guided Biopsy/adverse effects , Lung/diagnostic imaging , Lung Diseases/diagnostic imaging , Lung Neoplasms/diagnosis , Lung Neoplasms/pathology , Male , Middle Aged , Reproducibility of Results , Respiratory Tract Infections/diagnostic imaging , Retrospective Studies , Sensitivity and Specificity , Tomography, X-Ray Computed
18.
Clin Lab ; 65(1)2019 Jan 01.
Article in English | MEDLINE | ID: mdl-30775886

ABSTRACT

BACKGROUND: To report a case of broncholithiasis with recurrent hemoptysis and fever initially misdiagnosed as active tuberculosis. METHODS: The chest contrast-enhanced CT scan, electronic bronchoscope, and ultrathin bronchoscope were performed leading to the diagnosis of broncholithiasis, open lung lobectomy was done after thoracic surgery consultation. RESULTS: The chest contrast-enhanced CT scan showed a high-density intratracheal shadow and calcified lymph nodes. Ultrathin bronchoscopy manifested calcified lesions located at the distal portion of the right lower lobe bronchus. Histopathology of lobectomy showed lithiasis in the right lower lobe tracheobronchial tree. CONCLUSIONS: We should pay attention to calcified intratracheal lesions and make differential diagnosis with tuberculosis, especially when accompanied with calcified lymph nodes and fever.


Subject(s)
Bronchial Diseases/diagnosis , Fever/complications , Hemoptysis/complications , Lithiasis/diagnosis , Tuberculosis, Pulmonary/diagnosis , Tuberculosis/diagnosis , Adult , Bronchial Diseases/complications , Diagnosis, Differential , Diagnostic Errors , Female , Fever/pathology , Hemoptysis/pathology , Humans , Lithiasis/complications , Lung/diagnostic imaging , Lung/pathology , Lung/surgery , Pulmonary Surgical Procedures , Recurrence , Tomography, X-Ray Computed
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