Color Changes Associated with Sandblasting, Hydrofluoric Acid Etching, and Er:YAG Laser Irradiation of Milled Feldspathic Porcelain Laminate Veneers.

OBJECTIVES: To evaluate color changes in milled feldspathic porcelain laminate veneers following hydrofluoric acid etching (HFA), sandblasting (SB), or Er:YAG laser irradiation (LI). METHODS AND MATERIALS: Disc-shaped specimens (thickness=1 mm, diameter=8 mm) were milled from feldspathic porcelain blocks (n=40). Glazed specimens were randomly assigned to four subgroups (n=10 each) according to surface treatment: negative control, HFA, SB, and LI. A layer of translucent, light-cured resin cement (thickness=0.1 mm) was then applied following silanization. The color was characterized by the L*, a*, and b* uniform color space (CIE) using a reflection spectrophotometer. CIEDE2000 (ΔE00) was calculated to determine the color difference between each surface treatment and negative control groups. Data were statistically analyzed using analysis of variance (ANOVA), Kruskal-Wallis, and Dunn-Bonferroni post hoc tests. RESULTS: There were no significant differences in CIEL* and CIEb* coordinates between negative control and all surface treatment groups (p≥0.108). The SB group demonstrated significantly lower mean CIEa* (higher greenish hue) compared to other groups (p≤0.003). HFA exhibited significantly higher CIEa* (closer to red) when compared to LI (p=0.039). LI induced the smallest overall color change compared to negative control (ΔE00=1.43 [1.07]). However, the differences in ΔE00 values were not statistically significant (p=0.648). CONCLUSIONS: The tested surface treatments did not affect the lightness or the yellowness of the 1-mm-thick milled feldspathic porcelain veneers. However, sandblasting resulted in a significant increase in the greenish hue. The Er:YAG laser resulted in the closest ΔE00 (1.43) to the 50:50% perceptibility threshold (ΔE00=1.2).

Calcium, magnesium and aluminium ions as decontaminating agents against dermal fluoride absorption following hydrofluoric acid exposure.

The fluoride ions of the industrially largely irreplaceable, locally corrosive hydrofluoric acid (HF) can scavenge cations in biological tissues, which explains their high toxic potential, and also leads to local acidification through proton release. The influence of three complexing agents, calcium (Ca2+) gluconate (as 2.5% Ca2+gel and individually (2.84%) or commercially (10%) formulated Ca2+solution), magnesium (Mg2+) gluconate (2.84%) solution and aluminium (Al3+) solution (Hexafluorine®, pure and diluted) on the absorption of fluoride following HF exposure (1-3 min, 100 µl, 30%/0.64 cm2) through human skin was investigated in an ex-vivo diffusion cell model. Fluoride absorption was assessed over 6-24 h and analysed with a fluoride electrode. Decreasing the contamination time reduced the fluoride absorption distinctly which was further reduced by the application of fluoride-binding decontamination agents (Ca2+, Mg2+, Al3+) or water alone without being significantly different. Ca2+ appeared slightly more effective than Mg2+ in reducing fluoride absorption. Moreover, the addition of pH adjusting buffer promoted the decontamination efficacy. Fluoride-binding agents can facilitate the decontamination of dermal HF exposure. However, prompt decontamination appeared to be the key to successful limitation of fluoride absorption and pushes the choice of decontamination agent almost into the background.

Effect of hydrofluoric acid concentration and etching time on resin-bond strength to different glass ceramics.

The objective of this study was to evaluate the effect of the hydrofluoridric acid (HF) concentration and time of acid conditioning on bond strength of three glass ceramics to a resin cement. Thus, fifty blocks (10 mm x 5 mm x 2 mm) of each ceramic (LDCAD: IPS e.max CAD; LCAD: IPS Empress CAD and LDHP: IPS e.max Press) were made and embedded in acrylic resin. The surfaces were polished with sandpaper (#600, 800, 1000, and 1200 grits) and blocks were randomly divided into 15 groups (n = 10) according to the following factors: Concentration of HF (10% and 5%), conditioning time (20 s and 60 s) and ceramic (LDCAD, LDHP, and L). After conditioning, silane (Prosil / FGM) was applied and after 2 min, cylinders (Ø = 2 mm; h = 2 mm) of dual resin cement (AllCem / FGM) were made in the center of each block using a Teflon strip as matrix and light cured for 40 s (1,200 mW/cm2). Then, the samples were thermocycled (10,000 cycles, 5/55°C, 30s) and submitted to the shear bond test (50 KgF, 0.5 mm/min). The data (MPa) were analyzed with 3-way ANOVA and Tukey's test (5%). Failure analysis was performed using a stereomicroscope (20x) and a scanning electron microscope (SEM). ANOVA revealed that the "concentration" factor (p = 0.01) and the interaction "acid concentration X ceramic" (p = 0.009) had a significant effect, however, the "ceramic" (p = 0.897) and "conditioning time" (p = 0.260) factors did not influence the results. The LDHP10%60s (10.98 MPa)aA* group presented significantly higher bond strength than LDHP10%20s (6.57 MPa)bA, LCAD5%20s (6,90 ±3,5)aB and LDHP5%60s (5.66 ± 2,9MPa)aA* groups (Tukey). Failure analysis revealed that 100% of specimens had mixed failure. In conclusion, etching with 5% HF for 20 seconds is recommended for lithium disilicate and leucite-reinforced CAD/CAM ceramics. However, for pressed lithium disilicate ceramic, 10% HF for 60 s showed significantly higher bond strength to resin cement.

Effect of hydrofluoric acid concentration and etching time on resin-bond strength to different glass ceramics

Abstract: The objective of this study was to evaluate the effect of the hydrofluoridric acid (HF) concentration and time of acid conditioning on bond strength of three glass ceramics to a resin cement. Thus, fifty blocks (10 mm x 5 mm x 2 mm) of each ceramic (LDCAD: IPS e.max CAD; LCAD: IPS Empress CAD and LDHP: IPS e.max Press) were made and embedded in acrylic resin. The surfaces were polished with sandpaper (#600, 800, 1000, and 1200 grits) and blocks were randomly divided into 15 groups (n = 10) according to the following factors: Concentration of HF (10% and 5%), conditioning time (20 s and 60 s) and ceramic (LDCAD, LDHP, and L). After conditioning, silane (Prosil / FGM) was applied and after 2 min, cylinders (Ø = 2 mm; h = 2 mm) of dual resin cement (AllCem / FGM) were made in the center of each block using a Teflon strip as matrix and light cured for 40 s (1,200 mW/cm2). Then, the samples were thermocycled (10,000 cycles, 5/55°C, 30s) and submitted to the shear bond test (50 KgF, 0.5 mm/min). The data (MPa) were analyzed with 3-way ANOVA and Tukey's test (5%). Failure analysis was performed using a stereomicroscope (20x) and a scanning electron microscope (SEM). ANOVA revealed that the "concentration" factor (p = 0.01) and the interaction "acid concentration X ceramic" (p = 0.009) had a significant effect, however, the "ceramic" (p = 0.897) and "conditioning time" (p = 0.260) factors did not influence the results. The LDHP10%60s (10.98 MPa)aA* group presented significantly higher bond strength than LDHP10%20s (6.57 MPa)bA, LCAD5%20s (6,90 ±3,5)aB and LDHP5%60s (5.66 ± 2,9MPa)aA* groups (Tukey). Failure analysis revealed that 100% of specimens had mixed failure. In conclusion, etching with 5% HF for 20 seconds is recommended for lithium disilicate and leucite-reinforced CAD/CAM ceramics. However, for pressed lithium disilicate ceramic, 10% HF for 60 s showed significantly higher bond strength to resin cement.

Fatigue failure load of feldspathic ceramic crowns after hydrofluoric acid etching at different concentrations.

STATEMENT OF PROBLEM: Hydrofluoric acid etching modifies the cementation surface of ceramic restorations, which is the same surface where failure is initiated. Information regarding the influence of hydrofluoric acid etching on the cyclic loads to failure of ceramic crowns is lacking. PURPOSE: The purpose of this in vitro study was to evaluate the influence of different hydrofluoric acid concentrations on the fatigue failure loads of feldspathic ceramic crowns. MATERIAL AND METHODS: Eighty feldspathic ceramic crowns were cemented with resin cement to identical simplified complete crown preparations machined in a dentin-like polymer. The preparations were etched with 10% hydrofluoric acid for 60 seconds and received a primer coating. Before cementation, the intaglio of the ceramic crowns was treated with 1 of 4 surface conditionings (n=20): nonconditioned (control, CTRL), or etched for 60 seconds with different hydrofluoric acid concentrations: 1% (HF1), 5% (HF5), and 10% (HF10). A silane coupling agent was applied on this surface of all crowns, which were cemented to the preparations. Each crown was cyclically loaded in water with a G10 epoxy-glass piston positioned in the center of the occlusal surface. Fatigue failure loads of ceramic crowns were obtained by the staircase approach after 500000 cycles at 20 Hz. Mean failure loads were analyzed by 1-way ANOVA and the Tukey test (α=.05). RESULTS: Mean failure loads of groups CTRL (245.0 ±15.1 N), HF1 (242.5 ±24.7 N), and HF10 (255.7 ±53.8 N) were statistically similar (P>.05), while that of the HF5 group (216.7 ±22.5 N) was significantly lower (P<.05). CONCLUSIONS: HF5 acid had a negative effect on the fatigue loads of the tested feldspathic ceramic crowns, while HF1 and HF10 acids did not change the fatigue resistance.

Durabilidade de união e carga cíclica para falha do silicato de litío reforçado por zircônia após cimentação adesiva / Bond stregth and and fadigue failure load of a zirconia reinforced lithium silicate ceramic after adhesive cementation

No presente trabalho, avaliou-se o efeito de diferentes concentrações de ácido fluorídrico (5% e 10%), na resistência de união entre uma cerâmica de silicato de lítio reforçado por zircônia (sem cristalização adicional, com queima de glaze e com queima adicional de cristalização) e um cimento resinoso, com e sem envelhecimento. Avaliou-se também o comportamento em fadiga de uma cerâmica à base de silicato de lítio reforçado por zircônia (sem cristalização adicional, com de queima de glaze e com queima adicional de cristalização) cimentada adesivamente a um material análogo a dentina (NEMA G10), na ausência ou presença de envelhecimento. Para o teste de microtração os blocos cerâmicos de silicato de lítio reforçado por zircônia foram cortados em blocos menores e divididos aleatoriamente em 12 grupos (N = 72; n = 6). No teste de fadiga os espécimes foram em formato de discos (diâmetro de 12 mm e espessura de 1,2 mm) cimentados a discos de resina epoxi Nema G10 (diâmetro de 12mm e espessura de 2,3mm), divididos em 6 grupos (N = 120; n = 20) e submetidos a ensaio de fadiga pelo método da escada (100.000 ciclos, 20 Hertz de frequência). Os dados resistência de união (MPa) e fadiga (N) foram submetidos à ANOVA 2-fatores, e respectivamente submetidos aos testes de Tukey e Bonferroni (p<0,05). Os resultados mostraram diferença estatisticamente significante para o fator "termociclagem" (ANOVA 2 fatores, p<0,05) sendo os grupos sem termociclagem superiores aos grupos com envelhecimento (Tukey). O teste de Bonferroni indicou que dentro da mesma condição (sem termociclagem ou com termociclagem), os grupos com queimas adicionais cristalização ou glaze apresentam resultados superiores aos grupos sem realização de queimas adicionais. Dessa forma, a união entre ZLS e cimento resinoso foi negativamente afetada pelo envelhecimento térmico em água. Já o comportamento em fadiga dos discos de ZLS cimentados em Nema G10 foi superior nos grupos que receberam queimas de glaze ou de cristalização e inferior nos grupos envelhecidos(AU)

This study evaluated the effect of different hydrofluoric acid concentrations (5% and 10%) on the bond strength between a zirconium-reinforced lithium silicate ceramic (without additional crystallization, glaze firing and additional crystallization firing) and a resinous cement, with and without aging. The fatigue behavior of a zirconium-reinforced lithium silicate-based ceramic (without additional crystallization, glaze firing and additional crystallization firing) adhesively cemented to a material like dentin (NEMA G10) was also evaluated with or without thermal aging. For the microtensile test, the zirconia reinforced lithium silicate ceramic blocks were cut into smaller blocks and randomly divided into 12 groups (N=72; n=6). In the fatigue test, discs (diameter 12 mm and thickness 1.2 mm) were cut, cemented to NEMA G10 epoxy resin discs (diameter 12 mm and thickness 2.3 mm), assigned into 6 groups (N=120, n=20) and subjected to the fatigue test by the ladder method (100,000 cycles, 20 Hertz frequency). The bond strength (MPa) and fatigue (N) data were submitted to 2-Way ANOVA, and respectively submitted to Tukey and Bonferroni tests (p <0.05). The results showed a statistically significant difference for the "thermocycling" factor (2-Way ANOVA, p <0.05), with the groups without thermocycling been superior to the aged groups (Tukey). The Bonferroni test indicated that within the same condition (with or without thermocycling), the groups with additional crystallization or glaze firing showed higher results than the groups without additional firing. Thus, the bond between ZLS and the resin cement was negatively affected by thermal aging in water. On the other hand, the fatigue behavior of ZLS discs cemented on NEMA G10 was higher in the groups that received glaze or crystallization firing and lower in the aged groups(AU)

Durabilidade de união e carga cíclica para falha do silicato de litío reforçado por zircônia após cimentação adesiva / Bond stregth and and fadigue failure load of a zirconia reinforced lithium silicate ceramic after adhesive cementation

No presente trabalho, avaliou-se o efeito de diferentes concentrações de ácido fluorídrico (5% e 10%), na resistência de união entre uma cerâmica de silicato de lítio reforçado por zircônia (sem cristalização adicional, com queima de glaze e com queima adicional de cristalização) e um cimento resinoso, com e sem envelhecimento. Avaliou-se também o comportamento em fadiga de uma cerâmica à base de silicato de lítio reforçado por zircônia (sem cristalização adicional, com de queima de glaze e com queima adicional de cristalização) cimentada adesivamente a um material análogo a dentina (NEMA G10), na ausência ou presença de envelhecimento. Para o teste de microtração os blocos cerâmicos de silicato de lítio reforçado por zircônia foram cortados em blocos menores e divididos aleatoriamente em 12 grupos (N = 72; n = 6). No teste de fadiga os espécimes foram em formato de discos (diâmetro de 12 mm e espessura de 1,2 mm) cimentados a discos de resina epoxi Nema G10 (diâmetro de 12mm e espessura de 2,3mm), divididos em 6 grupos (N = 120; n = 20) e submetidos a ensaio de fadiga pelo método da escada (100.000 ciclos, 20 Hertz de frequência). Os dados resistência de união (MPa) e fadiga (N) foram submetidos à ANOVA 2-fatores, e respectivamente submetidos aos testes de Tukey e Bonferroni (p<0,05). Os resultados mostraram diferença estatisticamente significante para o fator "termociclagem" (ANOVA 2 fatores, p<0,05) sendo os grupos sem termociclagem superiores aos grupos com envelhecimento (Tukey). O teste de Bonferroni indicou que dentro da mesma condição (sem termociclagem ou com termociclagem), os grupos com queimas adicionais cristalização ou glaze apresentam resultados superiores aos grupos sem realização de queimas adicionais. Dessa forma, a união entre ZLS e cimento resinoso foi negativamente afetada pelo envelhecimento térmico em água. Já o comportamento em fadiga dos discos de ZLS cimentados em Nema G10 foi superior nos grupos que receberam queimas de glaze ou de cristalização e inferior nos grupos envelhecidos(AU)

This study evaluated the effect of different hydrofluoric acid concentrations (5% and 10%) on the bond strength between a zirconium-reinforced lithium silicate ceramic (without additional crystallization, glaze firing and additional crystallization firing) and a resinous cement, with and without aging. The fatigue behavior of a zirconium-reinforced lithium silicate-based ceramic (without additional crystallization, glaze firing and additional crystallization firing) adhesively cemented to a material like dentin (NEMA G10) was also evaluated with or without thermal aging. For the microtensile test, the zirconia reinforced lithium silicate ceramic blocks were cut into smaller blocks and randomly divided into 12 groups (N=72; n=6). In the fatigue test, discs (diameter 12 mm and thickness 1.2 mm) were cut, cemented to NEMA G10 epoxy resin discs (diameter 12 mm and thickness 2.3 mm), assigned into 6 groups (N=120, n=20) and subjected to the fatigue test by the ladder method (100,000 cycles, 20 Hertz frequency). The bond strength (MPa) and fatigue (N) data were submitted to 2-Way ANOVA, and respectively submitted to Tukey and Bonferroni tests (p <0.05). The results showed a statistically significant difference for the "thermocycling" factor (2-Way ANOVA, p <0.05), with the groups without thermocycling been superior to the aged groups (Tukey). The Bonferroni test indicated that within the same condition (with or without thermocycling), the groups with additional crystallization or glaze firing showed higher results than the groups without additional firing. Thus, the bond between ZLS and the resin cement was negatively affected by thermal aging in water. On the other hand, the fatigue behavior of ZLS discs cemented on NEMA G10 was higher in the groups that received glaze or crystallization firing and lower in the aged groups(AU)

Effect of Hydrofluoric Acid Concentration and Etching Time on Bond Strength to Lithium Disilicate Glass Ceramic.

The aim of this study was to evaluate the influence of different concentrations of hydrofluoric acid (HF) associated with varied etching times on the microshear bond strength (µSBS) of a resin cement to a lithium disilicate glass ceramic. Two hundred seventy-five ceramic blocks (IPS e.max Press [EMX], Ivoclar Vivadent), measuring 8 mm × 3 mm thickness, were randomly distributed into five groups according to the HF concentrations (n=50): 1%, 2.5%, 5%, 7.5%, and 10%. Further random distribution into subgroups was performed according to the following etching times (n=10): 20, 40, 60, 120, and 20 + 20 seconds. After etching, all blocks were treated with a silane coupling agent followed by a thin layer of an unfilled resin. Three resin cement cylinders (∅=1 mm) were made on each EMX surface, which was then stored in deionized water at 37°C for 24 hours before testing. The µSBS was in a universal testing machine at a crosshead speed of 1 mm/min until failure. Data were submitted to two-way analysis of variance, and multiple comparisons were performed using the Tukey post hoc test (α=0.05). One representative EMX sample was etched according to the description of each subgroup and evaluated using scanning electron microscopy for surface characterization. The HF concentrations of 5%, 7.5%, and 10% provided significantly higher µSBS values than 1% and 2.5% (p<0.05), regardless of the etching times. For 1% and 2.5% HF, the etching times from 40 to 120 seconds increased the µSBS values compared with 20 seconds (p<0.05), but etching periods did not differ within the 5%, 7.5%, and 10% HF groups (p>0.05). The effect of re-etching was more evident for 1% and 2.5% HF (p<0.05). Different HF concentrations/etching times directly influenced the bond strength and surface morphology of EMX.

Evaluación in vitro del efecto de la concentración y el tiempo de aplicación del ácido fluorhídrico sobre la resistencia a la flexión biaxial y la rugosidad del disilicato de litio de última generación / In vitro evaluation of the effect of concentration and time of application of hydrofluoric acid on the biaxial flexural strength and roughness of lithium disilicate

El objetivo fue evaluar in vitro el efecto de la concentración y del tiempo de aplicación del ácido fluorhídrico sobre la rugosidad de la superficie y la resistencia a la fractura de la cerámica de Disilicato de litio de última generación. Se fabricaron 90 discos de cerámica IPS e.max press (14 mm diámetro, 1,2 mm espesor), mediante la técnica de inyección y posterior pulido. Se utilizaron 60 discos para evaluar la resistencia a la flexión biaxial mediante la prueba del pistón y las 3 esferas; se realizó un acondicionamiento con ácido fluorhídrico al 4,6% y al 9,5% durante 20, 40 y 60 segundos (10 discos por cada tiempo y concentración). Los 30 discos restantes se utilizaron para medir los valores de rugosidad superficial (Ra) con ácido fluorhídrico al 4,6% y al 9,5% durante 20, 40 y 60 segundos (5 discos por grupo) mediante microscopia óptica 3D, la cual permitió medir los valores de Rugosidad (Ra). Los datos fueron analizados mediante una prueba de ANOVA y Post- Hoc para determinar las diferencias significativas entre los grupos de estudio. Los valores promedio de la resistencia a la flexión biaxial en los grupos 1, 2 y 3 con la aplicación del ácido fluorhídrico al 4,6% y tiempos de 20, 40 y 60 fueron de 448,45±68,1 Mpa, 357,23±59,5 Mpa y 317,69±45,97 Mpa, respectivamente. Los valores en los grupos al 9,6% fueron de 365,40±46,93 Mpa, 334,38±40,75 Mpa y 348,83±79,39 Mpa. La resistencia a la flexión biaxial de la cerámica de disilicato de litio de última generación se ve afectada por la concentración y el tiempo de aplicación del ácido fluorhídrico. A mayor tiempo de aplicación y concentración del ácido fluorhídrico, menor la resistencia del material. El efecto de la concentración del ácido fluorhídrico y el tiempo de aplicación sobre la cerámica de disilicato de litio no altera significativamente su rugosidad superficial. Según los valores de resistencia a la flexión biaxial encontrados en el presente estudio se recomienda el uso del ácido fluorhídrico a una concentración 4,6% por 20 segundos tal como lo indica el fabricante.

The purpose of this study was to evaluate in vitro the effect of concentration and time of application of hydrofluoric acid on the surface roughness and fracture resistance of lithium disilicate ceramic generation. 90 IPS e.max press ceramic discs (14 mm diameter, 1.2 mm thick) were fabricated by the press technique and then polished. 60 discs to evaluate the biaxial flexural strength test by the piston and the three spheres were used; under 4.6% hydrofluoric acid and 9.6% conditioned treatment was carried out for 20, 40 and 60 seconds (10 disks per each time and concentration). The remaining 30 discs were used to measure the surface roughness values (Ra) with 4.6% and 9.6% hydrofluoric acid for 20, 40 and 60 seconds (5 discs per group) using 3D optical microscopy, which it possible to measure the values of roughness (Ra). Data were analyzed by ANOVA and Post Hoc to determine significant differences between the study groups. Average values of the biaxial flexural strength in groups 1, 2 and 3 with the application of 4.6% HFL and times of 20, 40 and 60 seconds were 448.45±68.1 MPa, 357.23±59.5 MPa and 317.69±45.97 MPa respectively. The values in groups of 9.6% were 365.40±46.93 MPa, 334.38±40.75 and 348.83±79.39 Mpa. The biaxial flexural strength of the ceramic lithium disilicate generation is affected by the concentration and time of application of hydrofluoric acid. A longer time of application and concentration of hydrofluoric acid, less material strength. The effect of the concentration of hydrofluoric acid and application time on the ceramic lithium disilicate did not significantly alter the roughness of the ceramic surface. According to the values of biaxial flexural strength found in the present study the use of hydrofluoric acid is recommended at a concentration 4.6% for 20 seconds as indicated by the manufacturer.

Influence of hydrofluoric acid concentration on the flexural strength of a feldspathic ceramic.

This study evaluated the effects of etching with increasing hydrofluoric (HF) acid concentrations on the roughness and flexural strength of a feldspathic ceramic. One hundred and fifty ceramic specimens (14×4×1.2 mm(2)) were produced from ceramic blocks (VitaBlocks Mark II). All specimens were polished, chamfered and sonically cleaned in isopropyl alcohol. Specimens were randomly divided into 5 groups (n=30): SC (control) no ceramic surface etching; HF1, HF3, HF5 and HF10 ceramic surface etching for 60s with 1%, 3%, 5% and 10% HF acid concentrations, respectively. Profilometry was performed in all specimens to evaluate roughness prior to flexural strength testing. Data were analyzed using one-way ANOVA and Tukey׳s test (α=0.05). Weibull module (m) and characteristic stress (σc) were also determined. HF acid etching, regardless of the concentration used, led to significantly rougher surfaces than the control (p<0.05). However, the mean flexural strength values were not statistically different among the etched groups (106.47 to 102.02 MPa). Acid etching significantly reduced the mean flexural strength when compared with the control (143.3 MPa). Weibull modulus of the groups was similar, except for the HF5 group that was higher compared to HF3. Flexural strength was similarly affected by the different HF acid concentrations tested, but roughness increased higher the acid concentration. Ceramic etching led to a significant reduction in strength when compared to the untreated ceramic, regardless of its concentration.

Effect of hydrofluoric acid concentration and etching duration on select surface roughness parameters for zirconia.

STATEMENT OF PROBLEM: The surface of zirconia is resistant to chemical treatment. Roughening the surface of densely sintered zirconia still poses a challenge in dentistry. PURPOSE: The purpose of the study was to examine the effects of hydrofluoric acid on the quality of surface roughening of zirconia. MATERIAL AND METHODS: One hundred cylindrical disks made from zirconia (Ceramill Zi; Amann Girrbach AG) were divided into 4 groups. Three groups (n=30) were distinguished on the basis of hydrofluoric acid (HF) concentration: 40% HF, 9.5% HF, and 5% HF. The groups were then further divided into 3 groups of 10 specimens, each based on etch time (1, 5, or 15 minutes). The control group (n=10) consisted of specimens polished with SiC abrasive paper. The surface was examined with scanning electron microscopy, and the roughness was measured with a profilometer and confocal laser scanning microscope. The mean arithmetic profile deviation (Ra(mean)) and mean maximum height of profile (Rz(mean)) results for the etched surfaces in relationship to the baseline surfaces were compared with the Student t test for averaged data (α=.05). RESULTS: When etched with 40% HF concentration, the Ra(mean) and Rz(mean) results were statistically higher (P<.01) for the etched surfaces than for the baseline surfaces. When etched with 9.5% HF concentration, the higher Ra(mean) and Rz(mean) results were only statistically significant (P<.01) after 15 minutes. Etching with 5% HF concentration showed no significant differences (P>.05). CONCLUSIONS: Etching with a 5% HF solution should not be recommended as a method for roughening zirconia surfaces.

O ácido fluorídrico na resistência ao cisalhamento entre cerâmica feldspática e resina composta / The hydrofluoric acid in the shear strength between feldspathic ceramic and composite resin

Dentre os materiais restauradores, a porcelana se destaca pelo seu alto potencial em reproduzir o aspecto dental. Desta maneira, a sua utilização vem crescendo cada vez mais, e com ela a possibilidade de fraturas. Entretanto, nem sempre uma falha exige a troca da restauração, pois existe a possibilidade de um reparo utilizando resina composta. Este estudo avaliou a resistência ao cisalhamento entre resina composta e cerâmica feldspática submetida ao condicionamento com ácido fluorídrico (HF) em diferentes concentrações. Foram confeccionadas 36 pastilhas de porcelana feldspática e incluídas em resina acrílica, aplainadas com lixas d’água, asperizadas com pontas diamantadas e divididas em três grupos (n=12) de acordo com os tratamentos de superfície: G1) sem condicionamento (controle); G2) condicionamento com HF a 10% por 120 segundos; G3) condicionamento com HF a 5% por 120 segundos. Em seguida, silano e adesivo foram aplicados sobre a superfície da porcelana, seguido da inserção da resina composta com o auxílio de uma matriz metálica bipartida. Após sete dias de armazenamento em estufa, os corpos de prova foram submetidos ao teste de cisalhamento em uma máquina de ensaios universal (EMIC). As médias de resistência foram: G1 105,3N; G2 182,5N e G3 154,51N. Na análise dos dados quantitativos (T student) houve diferença estatística significante entre todos os grupos (p<0,05). A microscopia óptica revelou aproximadamente 58% de falhas coesivas para o G1, 75% para o G3 e 83% para o G2. Concluiu-se que a adesão com o uso do HF a 10% foi superior a adesão obtida quando utilizado o HF a 5%.

Among the restorative materials the porcelain is distinguished by its high potential in reproducing the dental aspect. In this way, their use has been growing increasingly, and, with it the possibility of fracture. However, not every failure demands the exchange the restoration because the possibility of a repair exists with compounded resin. This study evaluated the shear bond strength between composite resin and feldspathic ceramic subjected to etching surface with hydrofluoric acid (HF) at different concentrations. Thirty-six porcelain specimens were mounted into acrylic resin, polished and divided into 3 groups (n=12), according to the following surface treatments: G1) without treatment (control); G2) etched with 10% HF for 120 seconds; G3) etched with 5% HF for 120 seconds. Then the treatment, silane coupling agent and adhesive were applied to the treated specimens, after being bonded with of composite resin with the aid of a bipartite metal matrix. After a 7 days of storage at 37° C, the specimens were subjected to a shearing force in a universal testing machine at a crosshead speed of 0.5 mm/min. The average shear strength were: G1 105.3 N; G2 182.5 N and G3 154.51 N. In the analysis of quantitative data (T student) was difference statistically significant between all groups (p <0.05). Optical microscopy revealed approximately 58% of cohesive failures in the control group, 75% to G3 and 83% for G2. It was concluded that adherence with HF was 10% greater adhesion with the 5% HF.

The effect of hydrofluoric acid treatment on titanium implant osseointegration in ovariectomized rats.

This study aimed to investigate the effects of hydrofluoric acid (HF) treatment of grit-blasted Ti implants on osseointegration in ovariectomized (OVX) rats. After blasting with aluminium oxide particles, half implants were treated with 0.2 vol.% HF, and the other half were kept non-modified as control. The topographical and chemical changes of implant surface were determined by Scanning Electron Microscope, Atomic Force Microscope, and X-ray Photoemission Spectroscopy. 12 Weeks after bilateral ovariectomy, each rat accepted two implants in distal femora, with the control implant on the left and the fluoride-modified on the right. As a result, fluoride modification induced markedly changed surface topography and chemical composition. 12 Weeks after implant insertion, the fluoride-modified implants showed improved osseointegration compared to control, with the bone area ratio and bone-to-implant contact increased by 0.9- and 1.4-fold in histomorphometry, the bone volume ratio and percent osseointegration by 0.8- and 1.3-fold in micro-CT evaluation, and the maximal push-out force and ultimate shear strength by 1.2- and 2.0-fold in biomechanical test. These promising results indicated that HF treatment of Ti surface improved implant osseointegration in OVX rats, and suggested the feasibility of using fluoride modification to improve Ti implant osseointegration in osteoporotic bone.

In vivo and in vitro irritation testing of low concentrations of hydrofluoric acid.

OBJECTIVE: Acidic fluorides are proposed for the treatment of dental erosion. The aim of this study was to examine the irritation properties of dilute hydrofluoric acid (HF) solutions for potential use in the oral cavity. MATERIAL AND METHODS: Hen's egg test-chorioallantoic membrane (HET-CAM): The CAM was accessed by careful dissection through the egg shell (n=36, 6 eggs/test solution) and exposed to 300 µl of the HF solutions (0.05%, 0.10%, 0.20%, and 1.0%) under macroscope examination over the course of 5 min. Mean time-to-coagulation and average irritation score were recorded based on appearance of hemorrhage, coagulation, and lysis of the blood vessels in the membrane. Mouse skin test: 60 male mice were randomly divided into 10 groups of 6 animals each (control, 0.05%, 0.10%, 0.20%, and 1.0% HF), shaved on the back, exposed to test solution, and euthanized after 2 h or 24 h. Skin samples were evaluated by light microscopy, scoring epithelial leukocyte infiltration, vascular congestion, and edema. RESULTS: HET-CAM: 0.05% HF was slightly irritant, 0.1% HF moderately irritant, 0.2% and 1% HF strongly irritant. 0.1-1% HF solutions were severely irritating on the eye. Mouse skin test: HF concentration was significantly correlated with tissue response, and 24-h exposure to 1% HF solution showed focal erosion of the epithelium and marked localized subepithelial leukocyte infiltration. CONCLUSION: The results of the studies suggest that accidental exposure of soft tissues to solutions containing more than 0.2% HF may be harmful.

Time-dependent changes of blood parameters and fluoride kinetics in rats after acute exposure to subtoxic hydrofluoric acid.

OBJECTIVES: In our previous study, we reported that even a sublethal dose of hydrofluoric acid (HFA) could cause acute toxic effects 60 min after intravenous injection. This study was designed to investigate the time- and dose-dependent changes associated with these disorders. The serum fluoride (F) kinetics are also considered in the discussion of the relationship between the concentrations of serum F and the disorders. METHODS: Rats were injected with HFA (1.6 or 9.6 mg/kg body weight) for the dose-response relationship study. For each dose, the rats were assigned to one of seven groups. Blood samples of the 0-min group were obtained from the carotid artery prior to injection as a control. The other six groups were labeled according to sampling times (5, 10, 30, 60, 120 and 300-min) in the time-dependent study. RESULTS: The 1.6 mg/kg dose decreased the ionized calcium (Ca2+) level significantly after 30 min, and it also decreased the total calcium (Ca) level after 300 min. The 9.6 mg/kg dose rapidly worsened renal dysfunction after 60 min. It increased the serum potassium level after 60 and 120 min and it decreased Ca and Ca2+ levels until 300 min. Although there was respiratory compensation, the base excess and HCO3(-) level and had not completely recovered by 300 min. CONCLUSIONS: Even low exposure to HFA caused renal dysfunction, and electrolyte abnormalities and metabolic acidosis lasted for several hours in rats. Therefore, persons involved in HFA accidental exposure should be closely monitored over time, even if the exposure is less than the sublethal dose.

Effects of different silanes and acid concentrations on bond strength of brackets to porcelain surfaces.

The aim of this study was to determine the optimum silane-coupling agent and the optimum concentration of acid agent when bonding to porcelain surfaces. Eighty deglazed feldspathic porcelain discs with a diameter of 10 mm and a thickness of 2 mm mounted in acrylic resin blocks were randomly divided into four groups. In groups 1 and 2, the porcelain surfaces were etched with 9.6 per cent hydrofluoric (HF) acid and in groups 3 and 4 with 5 per cent HF acid. In groups 1 and 3, the Dynalock maxillary central incisor brackets were bonded with Pulpdent silane and Unite bonding adhesive and in groups 2 and 4 with Reliance silane and Unite. Shear forces were applied to the samples using an Instron universal test machine. The non-parametric Kruskal-Wallis test was used to determine significant differences in bond strengths between the four groups and Dunn's multiple comparison test to compare subgroups. The mean bond strengths and standard deviations of groups 1 to 4 were 5.51 +/- 1.19, 6.54 +/- 0.002, 4.55 +/- 1.93, and 6.39 +/- 0.45 MPa, respectively. Specimens bonded with Reliance showed a statistically significantly higher in vitro bond strength than those bonded with Pulpdent. The concentration of etching gels did not result in any statistically significant difference on the in vitro bond strength when evaluated separately.

The effects of acidic fluoride solutions on early enamel erosion in vivo.

Acidic fluoride solutions may reduce dental erosion. The aim of this study was to compare the effect of different acidic fluoride solutions on enamel dissolution using an established in vivo model. When possible 4 anterior teeth (255 teeth in a total of 67 subjects) were isolated and exposed to 0.01 M citric acid. The acid was collected in test tubes before (etch I) and 5 min after (etch II) application of test fluoride preparations. Acidic fluoride solutions (pH range 1.5-2.9), i.e. SnF(2), TiF(4) and hydrogen fluoride (HF) (all approx. 0.1 M F), HF (0.027, 0.055, 0.082 M F) and neutral NaF solution (0.1 M F) as control were applied to the labial surfaces of the teeth for 1 min (6 ml/min). Enamel dissolution was examined by chemical analysis of calcium content in the citric acid etch solutions using atom absorption spectrometry. The change in calcium concentration (DeltaCa) and the percentage of mean calcium reduction were calculated from the difference in calcium loss between etch I and etch II. Statistical analysis was carried out using the Wilcoxon signed rank test and Kruskal-Wallis tests with Dunn's multiple comparison. Results showed a mean DeltaCa of 0.671 mg/l (SD 0.625) for SnF(2), and ranged from 0.233 mg/l (SD 0.248) for the weakest HF solution to 0.373 mg/l (SD 0.310) for the strongest HF solution. This represented a 67% reduction in enamel dissolution for SnF(2) and a 40-76% reduction for the HF solutions. No reduction was observed for TiF(4) or NaF. The types of metal, pH and fluoride concentration are all important for the in vivo effect.

Toxic myocarditis due to oral ingestion of hydrofluoric acid.

We report the case of a 32-year-old man, admitted to cardiac care unit with congestive heart failure, caused by a reduced global cardiac function four months after oral hydrofluoric acid ingestion while attempting suicide. Biopsy results of left ventricular myocardium confirmed toxic myocarditis due to ingestion of hydrofluoric acid. This case represents an uncommon example of toxic myocarditis as a long-term complication of oral hydrofluoric acid ingestion. We recommend cardiological follow-up consultations in patients with hydrofluoric acid intoxication for early detection of cardiac deterioration.

Hydrofluoric acid burn in a child from a compressed air duster.

Abuse of fluorinated hydrocarbons is on the rise, especially among the adolescent population. These products are potentially hazardous and pose substantial risks when abused. The psychosocial aspects related to inhalant abuse, and the treatment of adolescents with inhalant injuries is unique. We retrospectively reviewed our experience with burns from these products. We present a case of a 12-year-old girl who suffered first- and second-degree burns to her face, neck, shoulder, and chest during an episode of recreational inhalant abuse with 1,1-difluoroethane from an aerosolized computer cleaner. This is one of the youngest cases reported in literature with such burns from questionable fluorinated hydrocarbon abuse. Because of the accessible nature of these compounds around homes, schools, and offices, it is critical for health care providers to have an awareness of the potential hazards and devastating consequences of their abuse. We propose an approach to the care of these patients that provides a focus on both prevention and attention to mental health.

Harmful effects and acute lethal toxicity of intravenous administration of low concentrations of hydrofluoric acid in rats.

The acute toxicity of hydrofluoric acid (HFA) was investigated in a 24-h lethal dose study of intravenous infusion in rats. The lethal dose lowest (LDLo) and LD50 were 13.1 and 17.4 mg/kg, respectively. Harmful systemic effects were also studied 1 h after acute sublethal exposure to HFA. The maximum dose was set at 9.6 mg/kg (LD5). Rats were injected with HFA (1.6, 3.2, 6.4 or 9.6 mg/kg), saline, sodium fluoride (NaF) or HCl solution. NaF and HCl solution concentrations corresponded to the F- and H+ concentrations of 9.6 mg/kg HFA. Blood urea nitrogen (BUN) and Cr were significantly increased in response to HFA concentrations greater than 3.2mg/kg. Acute glomerular dysfunction also occurred at HFA concentrations greater than 3.2 mg/kg. HCO3- and base excess (BE) were significantly decreased in the 6.4 and 9.6 mg/kg groups. Ca2+ was significantly decreased, and K+ was increased in the 9.6 mg/kg group. BUN was significantly increased in the NaF and HFA groups and was increased in the HFA group compared with that in the NaF group. Cr was significantly increased in the HFA group only. HCO3- and BE were significantly decreased in the NaF and HFA groups and were increased in the HFA group compared with values in the NaF group. Ca2+ was significantly decreased in the NaF and HFA groups, and K+ was significantly increased in the NaF and HFA groups. F- exposure directly affected serum electrolytes. Mortality was thought to be due to cardiac arrhythmia resulting from hypocalcemia and hyperkalemia. Metabolic acidosis and renal failure were more severe in response to HFA exposure than in response to NaF exposure because of more free F-, which has strong cytotoxicity, in the HFA group than in the NaF group. Lethal effects of HFA are promoted by exposure routes such as inhalation that cause rapid absorption into the body. Even low exposure to HFA can cause acute renal dysfunction, electrolyte abnormalities and metabolic acidosis. These complications result in a poor prognosis.