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J Clin Pathol ; 26(7): 499-502, 1973 Jul.
Article in English | MEDLINE | ID: mdl-4727059

ABSTRACT

Evaluation of a commercial preparation of (125)I-labelled albumin for use in the study of albumin metabolism is described. In eight subjects with normal albumin metabolism the proportion of the dose of radioiodide excreted was stable throughout a period of 17 days, indicating that there was no excessive denaturation of the iodinated albumin. Characteristics of albumin metabolism-pool sizes, catabolic rate, etc-were in agreement with currently accepted normal values. It is concluded that this preparation of iodinated albumin is suitable for metabolic use.


Subject(s)
Albumins/metabolism , Serum Albumin, Radio-Iodinated , Adult , Aged , Albuminuria , Female , Humans , Iodine Isotopes/urine , Male , Middle Aged , Plasma Volume , Protein Denaturation , Serum Albumin/analysis
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