ABSTRACT
In 188 coronary angiographies Jodamide was found to be a substance which resulted in good to excellent contrasts and is so the best basis for an exact evaluation. It caused a transient fall of heart rate and blood pressure. Changes of E.C.G. disappeared quickly. Severe disturbances of the heart rhythm didn't appear. Severe general reactions were seldom and never fatal. More frequently mild reactions occurred, but only in two cases a therapy was necessary. The results show that Jodamide is an excellent contrast medium for selective coronary angiography.
Subject(s)
Coronary Angiography , Iodamide/standards , Iodobenzoates/standards , Aortic Valve Insufficiency/diagnosis , Blood Pressure/drug effects , Cardiomyopathies/diagnosis , Contrast Media , Coronary Disease/diagnosis , Heart Rate/drug effects , Humans , Mitral Valve Insufficiency/diagnosisABSTRACT
Iodamide 420 is a high concentrated, water solubile contrast medium of 420 mg/ml iodine content. Clinical observations were made on 31 patients, following 68 contrast injections. The administered iodine solution amounted to 3 to 100 ml pro injection, i.e. 0.6 to 2.0 ml/kg body weight and a total of 12 to 160 ml, i.e. 0.8 to 5.0 mg/kg pro angiographic study. Tests of sensitivity were not done. Iodamide 420 is characterized by a strikingly good tolerability. No severe complication was observed. The side effects were rare and negligible. The use of this high concentrated contrast medium improves the quality of angiograms, especially in cases, where the injection of the necessary amount is troublesome due to the high flow/small catheter lumen ratio.
