[The effect of tachykinins microinjections into the solitary tract nucleus on respiration and blood circulation in rats]. / Vliianie mikroin''ektsií takhikininov v oblast' iadra solitarnogo trakta na dykhanie i krovoobrashchenie u krys.

Administration of substance P and kassinin into the solitary tract nucleus of anesthetized rats induced a dose-dependent increase in ventilation, tidal volume, inspiratory muscle activity, and a decrease in the mean blood pressure and heart rate. Microinjections of peptides caused a decrease in ventilatory response to hypoxia and an inhibition of the Breuer-Hering reflex. The data obtained suggest involvement of tachykinins in the respiratory and circulatory control via the solitary tract nucleus.