Klüver & Bucy syndrome: an investigation of social and affective cognition.

Klüver-Bucy syndrome (KBS) leads to important behavioral symptoms and social maladaptation. Rarely described, no previous study has investigated its social and affective cognitive profile. We report the case of ASP, a patient who developed a complete KBS at 9 years that evolved into an incomplete KBS. Orbitofrontal and temporal damages were evidenced. While a classic neuropsychological assessment showed a preserved global functioning, an extensive evaluation of her social and affective cognition (reversal learning, decision-making, emotion recognition, theory of mind, creative thinking) showed remarkable deficits. The relevancy of such findings for the characterization KBS and the field of neuropsychology are discussed.

Kluver-Bucy syndrome in one case with systemic lupus erythematosus.

Kluver-Bucy syndrome (KBS) is a collection of neuropsychiatric symptoms, including visual agnosia (prosopagnosia), hypermetamorphosis, placidity, hypersexuality, and hyperorality. Although neuropsychiatric manifestation is prevalent in cases with systemic lupus erythematosus (SLE), only one literature reported a case with SLE that had KBS previously. In this article, a 37-year-old woman with SLE who developed KBS and other neuropsychiatric symptoms is presented. Brain imaging proved the relevant structural lesion. The possible explanation of pathogenesis of KBS in SLE is discussed.

[Postraumatic klüver-Bucy syndrome--description and comparison of two clinical cases]. / Pourazowy zespól klüvera-Bucy'ego--opis i porównanie dwóch przypadków klinicznych.

AIM: Klüver-Bucy syndrome was described in the fifties of the 20th century as a group of neuropsychological symptoms, such as visual agnosia, "oral" tendency, hypermetamorphosis, changes in behaviour, hyper-sexuality (homo-, hetero-, autosexuality) and changes in dietary habits (anorexia, bulimia) that may develop in humans after bilateral damage or dysfunction of the medial temporal lobes. The cause of Klüver-Bucy syndrome may be an injury, central nervous system infection, especially herpetic, Pick disease, temporal epilepsy and paraneoplastic encephalopathy. The condition is very rare in children; its occurrence in childhood was described in a few cases only. Symptom intensity and their manifestation depend on numerous diversified factors. METHODS: A comparative presentation of two clinical cases of Klüver-Bucy syndrome following severe head injuries accompanied by description of computed tomography scans. RESULTS: The diagnosis of the syndrome does not require the presence of all the axial symptoms. Both patients were treated with carbamazepine. Regression of neuropsychological symptoms took a different course in each child, despite their similar brain damage. CONCLUSIONS: Fully symptomatic Klüver-Bucy syndrome is very rare. The psychological status of patients with this disorder depends not only on the extent of the lesion, but also on pre-injury emotional and intellectual development and post-injury social stimulation.