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J Ovarian Res ; 7: 36, 2014 Apr 07.
Article in English | MEDLINE | ID: mdl-24708577

ABSTRACT

A Krukenberg tumor is a rare and potentially deadly cause of elevated serum ß-hCG as part of a paraneoplastic syndrome. This study aims to describe the unusual case of a 36-year-old woman that presented to the Emergency Department (ED) with back pain and a positive urine pregnancy test. Assessment revealed no intrauterine pregnancy and a small left ovarian cyst. Further investigation showed moderately differentiated gastric adenocarcinoma with distant metastases to the spine. The patient died less than 3 months after her first presentation to the ED. Paraneoplastic syndrome, albeit rare, should be considered in the differential diagnosis of elevated ß-hCG due to the high mortality associated with Krukenberg tumors.


Subject(s)
Back Pain/etiology , Chorionic Gonadotropin, beta Subunit, Human/urine , Krukenberg Tumor/complications , Ovarian Neoplasms/complications , Pregnancy Tests , Adult , Back Pain/diagnosis , Biomarkers/blood , Biomarkers/urine , Biopsy , Chorionic Gonadotropin, beta Subunit, Human/blood , False Positive Reactions , Fatal Outcome , Female , Humans , Immunohistochemistry , Krukenberg Tumor/blood , Krukenberg Tumor/diagnosis , Krukenberg Tumor/therapy , Krukenberg Tumor/urine , Ovarian Neoplasms/blood , Ovarian Neoplasms/diagnosis , Ovarian Neoplasms/therapy , Ovarian Neoplasms/urine , Pain Measurement , Predictive Value of Tests , Time Factors , Tomography, X-Ray Computed , Treatment Outcome
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