ABSTRACT
Although diagnosis of cutaneous granulomatous disorders (CGDs) is usually suspected based on morphologic findings, localization, and anamnestic data, clinical differentiation from each other and from similar dermatoses may be challenging. Recently, dermatoscopy has been demonstrated to be a useful tool for assisting the recognition of several CGDs. This article provides a current overview of the dermatoscopic features of the main noninfectious and infectious CGDs, including sarcoidosis, necrobiosis lipoidica, granuloma annulare, rheumatoid nodules, and leishmaniasis. Other, less common, CGDs are briefly addressed, including granulomatous rosacea, acne agminata, and leprosy.
Subject(s)
Dermoscopy , Sarcoidosis/diagnostic imaging , Skin Diseases/diagnostic imaging , Granuloma Annulare/diagnostic imaging , Humans , Leishmaniasis, Cutaneous/diagnostic imaging , Leprosy, Borderline/diagnostic imaging , Lupus Vulgaris/diagnostic imaging , Necrobiosis Lipoidica/diagnostic imaging , Rheumatoid Nodule/diagnostic imagingSubject(s)
Lupus Erythematosus, Discoid/diagnostic imaging , Lupus Erythematosus, Discoid/diagnosis , Lupus Vulgaris/diagnostic imaging , Lupus Vulgaris/diagnosis , Tuberculosis, Cutaneous/diagnostic imaging , Tuberculosis, Cutaneous/diagnosis , Antibiotics, Antitubercular/therapeutic use , Female , Humans , Lupus Erythematosus, Discoid/drug therapy , Lupus Vulgaris/drug therapy , Middle Aged , Skin Neoplasms/diagnosis , Skin Neoplasms/diagnostic imaging , Skin Neoplasms/drug therapy , Tuberculosis, Cutaneous/drug therapyABSTRACT
We report a case of a 28-year-old female with the diagnosis of systemic lupus erythematosus (SLE) referred to our breast pathology consultancy in 2002 due to a left breast nodule. Further investigation revealed bilateral coarse calcifications. Biopsy was consistent with a diagnosis of lupus mastitis.
Subject(s)
Lupus Vulgaris/diagnosis , Mastitis/diagnosis , Adult , Antimalarials/therapeutic use , Biopsy, Needle , Diagnosis, Differential , Female , Humans , Hydroxychloroquine/therapeutic use , Lupus Vulgaris/diagnostic imaging , Lupus Vulgaris/drug therapy , Lupus Vulgaris/pathology , Mastitis/diagnostic imaging , Mastitis/drug therapy , Mastitis/pathology , Radiography , UltrasonographySubject(s)
Chagas Cardiomyopathy/complications , Chagas Cardiomyopathy/diagnostic imaging , Lupus Vulgaris/complications , Lupus Vulgaris/diagnostic imaging , Respiratory Distress Syndrome/diagnostic imaging , Respiratory Distress Syndrome/etiology , Sodium Pertechnetate Tc 99m/administration & dosage , Acute Disease , Administration, Inhalation , Adult , Chagas Cardiomyopathy/diagnosis , Diagnosis, Differential , Diagnostic Errors/prevention & control , Female , Humans , Lupus Vulgaris/diagnosis , Pulmonary Embolism/complications , Pulmonary Embolism/diagnosis , Pulmonary Embolism/diagnostic imaging , Radionuclide Imaging , Radiopharmaceuticals/administration & dosage , Rare Diseases/diagnosis , Rare Diseases/diagnostic imaging , Rare Diseases/etiology , Ventilation-Perfusion RatioABSTRACT
A prospective study was performed enrolling 11 newborns with neonatal lupus syndrome (NLS) and 22 control newborns to investigate cerebral ultrasound (US) anomalies and their relationship with clinical neurological signs and laboratory findings. Cerebral US detected a significantly higher incidence in the study group of both subependymal pseudocysts (SEPC) and subependymal hemorrhage (SEH), neither of which correlated to autoantibody levels. All infants had completely normal neurological examinations both at birth and follow-up. The etiopathogenesis of central nervous system findings in NLS is discussed. US evaluation identified minimal anomalies compatible with favorable outcome: further studies are necessary to investigate the possible long-term sequelae, pathogenesis and spectrum of cerebral US findings.
Subject(s)
Echoencephalography , Lupus Vulgaris/diagnostic imaging , Autoantibodies/immunology , Autoantigens , Brain Diseases/diagnostic imaging , Cerebral Hemorrhage/diagnostic imaging , Cysts/diagnostic imaging , Female , Follow-Up Studies , Humans , Infant, Newborn , Lupus Vulgaris/immunology , Male , Prospective Studies , Ribonucleoproteins/immunology , Syndrome , SS-B AntigenABSTRACT
We evaluated 4 cases of lupus enteritis by US, abdominal X-ray and CT. On US examinations, in particular, we observed ascites and edematous thickening of the small intestine where Kerckring folds with submucosal edema resembled an accordion. After steroid treatment and consequent improvement of the disease, we noticed disappearance of the intestinal thickening and ascites on US examination, compatible with the diagnosis of lupus enteritis. Based on these results, US was useful for the diagnosis and follow-up of lupus enteritis.
