ABSTRACT
Renal lymphangiomatosis is a rare disease characterized by lymphatic vessel proliferation. We present a case of an adult patient with chronic flank pain, hypertension, and a right kidney mass. The magnetic resonance imaging findings were consistent with unilateral renal lymphangiomatosis. Technetium-99m dimercaptosuccinic acid renal scintilography revealed decreased ipsilateral renal function. From these findings, the patient underwent right nephrectomy, which resulted in complete remission of his hypertension and pain.
Subject(s)
Hypertension/etiology , Kidney Neoplasms/complications , Kidney Neoplasms/diagnosis , Lymphatic Vessel Tumors/complications , Lymphatic Vessel Tumors/diagnosis , Adult , Humans , Kidney Neoplasms/surgery , Lymphatic Vessel Tumors/surgery , Magnetic Resonance Imaging , Male , NephrectomyABSTRACT
Lymphatic malformations and lymphatic-derived tumors commonly involve the head and neck, where they may be associated with bony abnormalities and other systemic symptoms. The reasons for the association between these disorders and local skeletal changes are largely unknown, but such changes may cause significant disease-related morbidity. Ongoing work in molecular and developmental biology is beginning to uncover potential reasons for the bony abnormalities found in head and neck lymphatic disease; this article summarizes current knowledge on possible mechanisms underlying this association.
Subject(s)
Bone Diseases/diagnosis , Head and Neck Neoplasms/diagnosis , Head and Neck Neoplasms/metabolism , Lymphatic Vessel Tumors/diagnosis , Lymphatic Vessel Tumors/metabolism , Bone Diseases/complications , Bone Diseases/diagnostic imaging , Bone and Bones/metabolism , Bone and Bones/pathology , Endothelial Cells/metabolism , Extracellular Matrix/metabolism , Extracellular Matrix/pathology , Head and Neck Neoplasms/complications , Humans , Lymphatic Vessel Tumors/complications , Radiography , Signal TransductionABSTRACT
Epstein-Barr virus (EBV) a ubiquitous gamma herpesvirus persists for life, generally without health consequences. However, it is associated with several well-recognized malignancies, such as Burkitt's lymphoma and nasopharyngeal carcinoma. A growing list of malignancies has been proposed to be EBV-associated: most of which are consistently EBV-positive whereas others show inconsistent results. The possible contribution of EBV to the development and/or progression of different "non-classical" tumors is discussed in terms of putative "non-traditional'' infection in EBV-related tumors.
Subject(s)
Breast Neoplasms/virology , Liver Neoplasms/virology , Lymphatic Vessel Tumors/virology , Breast Neoplasms/complications , Carcinoma/complications , Carcinoma/virology , Disease Progression , Epstein-Barr Virus Infections/complications , Epstein-Barr Virus Infections/virology , Female , Herpesvirus 4, Human/immunology , Humans , Liver Neoplasms/complications , Lymphatic Vessel Tumors/complications , Models, Biological , Salivary Gland Neoplasms/complications , Salivary Gland Neoplasms/virology , Stomach Neoplasms/complications , Stomach Neoplasms/virology , Uterine Cervical Neoplasms/complications , Uterine Cervical Neoplasms/virologyABSTRACT
No disponible
Subject(s)
Female , Infant , Humans , Lymphatic Vessel Tumors/complications , Lymphangioma, Cystic/pathology , Fever/etiology , Sclerotherapy , Skin Neoplasms/pathologyABSTRACT
Cervical lymphadenopathy is a common problem in children. The condition most commonly represents a transient response to a benign local or generalized infection, but occasionally it might herald the presence of a more serious disorder. Acute bilateral cervical lymphadenopathy usually is caused by a viral upper respiratory tract infection or streptococcal pharyngitis. Acute unilateral cervical lymphadenitis is caused by streptococcal or staphylococcal infection in 40% to 80% of cases. The most common causes of subacute or chronic lymphadenitis are cat scratch disease, mycobacterial infection, and toxoplasmosis. Supraclavicular or posterior cervical lymphadenopathy carries a much higher risk for malignancies than does anterior cervical lymphadenopathy. Generalized lymphadenopathy is often caused by a viral infection, and less frequently by malignancies, collagen vascular diseases, and medications. Laboratory tests are not necessary in the majority of children with cervical lymphadenopathy. Most cases of lymphadenopathy are self-limited and require no treatment. The treatment of acute bacterial cervical lymphadenitis without a known primary source should provide adequate coverage for both Staphylococcus aureus and group A beta hemolytic streptococci.
