1.
J Neurol
; 256(2): 264-5, 2009 Feb.
Article
in English
| MEDLINE
| ID: mdl-19266142
Subject(s)
DNA, Mitochondrial/genetics , Depressive Disorder/genetics , Depressive Disorder/metabolism , Genetic Predisposition to Disease/genetics , MERRF Syndrome/complications , MERRF Syndrome/genetics , Adult , Brain/metabolism , Brain/physiopathology , DNA Mutational Analysis , Depressive Disorder/physiopathology , Female , Genetic Markers/genetics , Genetic Testing , Genotype , Humans , MERRF Syndrome/psychology , Male , Middle Aged , Muscle Weakness/genetics , Muscle Weakness/metabolism , Muscle Weakness/physiopathology , Muscle, Skeletal/metabolism , Muscle, Skeletal/physiopathology , Mutation/genetics , RNA, Transfer, Lys/genetics
2.
CNS Spectr
; 12(4): 289-92, 2007 Apr.
Article
in English
| MEDLINE
| ID: mdl-17426666
ABSTRACT
A case is presented of a 56-year-old woman with a history of an eating disorder that preceded recognition of a mitochondrial myopathy. The possibility exists that her eating disorder was causally related to a more fundamental defect in mitochondrial oxidative metabolism. This case report highlights the phenotypic variability of mitochondrial myopathies. An increased risk of eating disorder may be associated with drugs that interfere with mitochondrial oxidative respiration.