[Immuno-oncologic monitoring of patients with bronchial carcinoma. III. Plasma glycoproteins]. / Monitoraggio immuno-oncologico di pazienti affetti da carcinoma bronchiale. Nota III. Le glicoproteine plasmatiche.

Alpha and beta serum glycoprotein levels were determined in lung cancer patients at time of diagnosis and during the natural course of the disease. The results do not suggest that these glycoproteins can be used as tumour markers. Moreover, some glycoproteins, which have activity in cell-mediated processes and macrophage functions, can suggest prognosis.

[Blood proteolytic enzyme inhibitors and their clinical study]. / Ingibitory proteoliticheskikh fermentov krovi i ikh issledovanie v klinike

Data on biochemistry, physiological significance and clinical investigations of two main inhibitors of proteinases in human blood serum (alpha 1-antitrypsin and alpha 2-macroglobulin) are reviewed. Physico-chemical properties of the inhibitors, mechanisms of their interaction with proteinases and methods for determination are discussed. Modification of the specificity of some proteinases by alpha 2-macroglobulin, which probably plays a significant role in the regulation of enzymatic systems of proteolysis in blood, is considered. The use of the inhibitors of proteolysis for diagnostics of pathological processes is discussed. Data on the alpha 1-antitrypsin deficiency and its relation to the development of degenerative diseases in lungs are reviewed.