ABSTRACT
Herpes virus type 1 and 2 antigens were detected in cells originating from malignant tumors with oromaxillofacial localization. A higher incidence of type 1 antigens was noted, as compared to the type 2. Investigated antigens were detected more frequently in the tumors of ectodermal origin. Antiherpesvirus FC antibodies were found in 74.5% of the tumor bearing subjects, but only in 22.3% of the controls.
Subject(s)
Antibodies, Viral/analysis , Antigens, Viral/analysis , Facial Neoplasms/microbiology , Maxillary Neoplasms/microbiology , Mouth Neoplasms/microbiology , Simplexvirus/isolation & purification , Adult , Aged , Aged, 80 and over , Complement Fixation Tests , Facial Neoplasms/pathology , Female , Fluorescent Antibody Technique , Humans , Maxillary Neoplasms/pathology , Middle Aged , Mouth Neoplasms/pathology , Simplexvirus/immunologyABSTRACT
SV40 antigen was detected on sections through malignant oromaxillofacial tumors in 47.8% of the cases, with a higher incidence among the epithelium originating tumors. Anti-SV40 CF antibodies were detected in 83.6% of the examined subjects with cancer, but only in 57.9% of the blood donors. The titers were quite low in general. The results are discussed from the point of view of the immunologic status of the patients.