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1.
Nutrients ; 13(9)2021 Aug 25.
Article in English | MEDLINE | ID: mdl-34578836

ABSTRACT

Growing evidence confirms choline as a critical perinatal nutrient. However, intake levels of choline and betaine among the Spanish fertile population remain unknown. Given their role in one-carbon metabolism with potential epigenetic effects, the aim of the present study was to evaluate the dietary intakes, their adequacy to existing guidelines and the main food sources together with other micronutrients involved in the methylation-methionine cycle (vitamin B6, folates and vitamin B12) in women of childbearing age. The ANIBES study, a cross-sectional study of a representative sample of women of childbearing age (18-45 years, n = 641) resident in Spain, was used. The sample was divided into younger women (18-30 years, n = 251) and older women (31-45 years, n = 390). Dietary intake was assessed by a three-day dietary record by using a tablet device. Total median intakes for the total sample were 303.9 mg/d for choline; 122.6 mg/d for betaine; 1.3 mg/d for vitamin B6; 140.8 µg/d for folates, and 3.8 µg/d for vitamin B12. The older subgroup showed significantly higher choline (p < 0.05), betaine (p < 0.001) and folates (p < 0.05) intakes than younger women. Main food sources for the whole sample were meat and meat products for choline (28.3%), vitamin B6 (25.7%) and vitamin B12 (22.8%); cereals and derivatives (79.9%) for betaine; vegetables (20.0%) for folates. Overall intake adequacy was only observed for vitamin B12, with a very limited number of participants showing adequate intakes for all the other micronutrients. These results illustrate there is a relevant need to raise awareness about optimizing the status of the methionine cycle-related vitamins and cofactors in this potentially vulnerable population.


Subject(s)
Diet/methods , Diet/statistics & numerical data , Food/statistics & numerical data , Methionine/administration & dosage , Nutrients/administration & dosage , Vitamin B Complex/administration & dosage , Adolescent , Adult , Age Factors , Betaine/administration & dosage , Choline/administration & dosage , Cross-Sectional Studies , Diet Records , Edible Grain , Female , Folic Acid/administration & dosage , Humans , Meat/statistics & numerical data , Methylation , Middle Aged , Spain , Vegetables , Vitamin B 12/administration & dosage , Vitamin B 6/administration & dosage , Young Adult
2.
Clin Nutr ; 40(7): 4551-4559, 2021 07.
Article in English | MEDLINE | ID: mdl-34229259

ABSTRACT

BACKGROUND & AIMS: Processed meat and high sodium intake are common in Western diet. The objective was to examine their independent effects on the risk of colorectal cancer (CRC). METHODS: We performed both observational analysis with UK Biobank and genetic analysis with Mendelian randomization (MR). The 24-h urinary sodium (UNa) and reported intake of processed meat were fitted on incident CRC by multivariable Cox proportional hazard model, adjusted for covariates, such as age, gender, family history, etc. Different sodium measures were used for sensitivity analyses. Two-sample MR analyses were performed using summary data from genome-wide association studies of UNa and CRC. Multivariable MR was adjusted for body mass index. RESULTS: We included 415 524 eligible participants from UK Biobank. During a median follow-up of 11.1 years, 2663 participants were diagnosed with CRC. High intake of processed meat independently increased risk of CRC by 23% (HR 1.23; 95% CI: 1.03 to 1.46), but 24-h UNa was not significantly associated with CRC (HR 0.96; 95% CI: 0.87 to 1.06). Furthermore, MR also showed little evidence for the effect of UNa on CRC (OR 1.02; 95% CI: 0.11 to 9.42). Sensitivity analyses showed consistent results across different measurements of sodium intake. CONCLUSIONS: Intake of processed meat had an independent effect on the risk of CRC, but the risk was not associated with sodium level. Reduction of processed meat intake may be an effective strategy for CRC prevention, while sodium reduction should still be recommended to achieve other health benefits.


Subject(s)
Colorectal Neoplasms/epidemiology , Colorectal Neoplasms/etiology , Diet/adverse effects , Meat/adverse effects , Sodium, Dietary/adverse effects , Biological Specimen Banks , Diet/statistics & numerical data , Female , Food Handling , Genome-Wide Association Study , Humans , Incidence , Male , Meat/statistics & numerical data , Mendelian Randomization Analysis , Middle Aged , Proportional Hazards Models , Prospective Studies , Sodium/urine , United Kingdom/epidemiology
3.
Ecotoxicol Environ Saf ; 215: 112133, 2021 Jun 01.
Article in English | MEDLINE | ID: mdl-33740488

ABSTRACT

BACKGROUND: Although short-term exposure to particulate matter (PM) was associated with increased glucocorticoids (GCs) levels, available evidence on associations of long-term exposure to PM and GCs levels is still scant. Previous studies has showed that meat intake is associated with sex hormones levels, but it is unknown whether meat intake is associated with GCs levels. Furthermore, the role of meat intake in the associations between PM and GCs levels remains unclear. AIMS: The aims of this study were to explore the associations of long-term exposure to PM and GCs levels among Chinese rural adults, and the role of meat intake in these associations. MATERIALS AND METHODS: A total of 6223 subjects were recruited from the Henan Rural Cohort Study. Serum GCs levels were measured with liquid chromatography-tandem mass spectrometry. The concentrations of PM (PM1 and PM2.5) for each subject were assessed with machine learning algorithms. The food frequency questionnaire (FFQ) was used to obtain each participant' information on meat intake. The effects of PM and meat intake on GCs levels were assessed using generalized linear models. In addition, modification analyses were performed to identify the role of meat intake played in the associations of PM with serum GCs levels. RESULTS: Per 1 µg/m3 increment in PM1 or PM2.5 concentration was associated with a 0.364 ng/ml (95% confidence interval (CI): 0.234, 0.494) or 0.227 ng/ml (95%CI: 0.110, 0.343) increase in serum cortisone, respectively. In addition, the moderation effects of total meat intake and red meat intake on the associations of long-term exposure to PM1 or PM2.5 with serum cortisone were observed (P < 0.05), indicating that individuals who had high levels of PM1 or PM2.5 and meat intake were more susceptible to have a higher state of serum cortisone. CONCLUSIONS: Our findings suggested that long-term exposure to PM1 or PM2.5 was associated with serum cortisone. Moreover, meat intake was found to be a significant moderator in the association of PM1 or PM2.5 with serum cortisone levels.


Subject(s)
Air Pollution/statistics & numerical data , Cortisone/blood , Diet/statistics & numerical data , Environmental Exposure/statistics & numerical data , Meat/statistics & numerical data , Particulate Matter/analysis , Adult , Air Pollutants/analysis , Air Pollution/analysis , Asian People , Cohort Studies , Cortisone/analysis , Environmental Exposure/analysis , Female , Humans , Linear Models , Male , Meat/analysis , Middle Aged , Rural Population
4.
Nutrients ; 13(2)2021 Feb 20.
Article in English | MEDLINE | ID: mdl-33672599

ABSTRACT

The association of meat consumption with mortality and morbidity for non-communicable diseases has been extensively studied. However, the relation of white meat consumption with health outcomes remains controversial. The present meta-analysis was conducted to comprehensively analyze the available evidence on the consistency and strength of the association between the consumption of white meat, death from any cause and incidence of fatal and non-fatal cardiovascular (CV) events. PubMed, Web of Science, Scopus and Embase databases were searched for articles published up to April 30, 2020. We included prospective cohort studies reporting relative risks and pertinent 95% confidence intervals (CI) for all-cause mortality and/or CV events (fatal or non-fatal). A total of 22 studies were included in the meta-analysis. Eleven studies (14 data sets) reported data on all-cause mortality, 10 studies (15 datasets) on cardiovascular disease (CVD) mortality and 10 studies (11 datasets) on non-fatal CV events. When comparing the highest versus the lowest consumption of white meat, the pooled OR and pertinent 95% CI were 0.94 (0.90, 0.97, p < 0.001) for all-cause mortality, 0.95 (0.89, 1.01, p = 0.13) for CV mortality, and 0.99 (0.95, 1.02, p = 0.48) for non-fatal CV events. In conclusion, the study shows for the first time a robust and inverse association between white meat consumption and all-cause mortality and a neutral association with CV mortality and morbidity. This highlights the importance of differentiating the meat types for what concerns their health effects and suggests that white meat might be a healthier alternative to read and processed meat consumption.


Subject(s)
Cardiovascular Diseases/mortality , Diet/mortality , Meat/statistics & numerical data , Aged , Cardiovascular Diseases/etiology , Cause of Death , Female , Heart Disease Risk Factors , Humans , Incidence , Male , Meat/analysis , Middle Aged , Prospective Studies , Red Meat/analysis , Red Meat/statistics & numerical data
5.
Clin Nutr ; 40(3): 1077-1084, 2021 03.
Article in English | MEDLINE | ID: mdl-32741682

ABSTRACT

BACKGROUND & AIMS: Accumulating evidence has linked distinct associations of red/processed and white meat consumption with chronic diseases and longevity among the general population. However, the associations of meat consumption and changes with mortality among hypertensive patients remain unknown. We aimed to assess the associations of red and white meat consumption with all-cause mortality among hypertensive patients in China. METHODS: We followed 8095 hypertensive patients from the China Health and Nutrition Survey between 1991 and 2015. In each survey year, 3-day 24-h dietary records were used to collect dietary data. Cumulative averages of dietary meat intake after the diagnosis of hypertension were calculated. Cox proportional hazards regression was used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) for mortality. RESULTS: Overall 927 deaths were documented among these hypertensive patients during an average of 11.4 years of follow-up. Red meat consumption was positively associated with all-cause mortality after multivariable adjustment [HR (95% CI) comparing the highest versus lowest quartile: 1.29 (1.05-1.57), P trend = 0.02]. White meat intake was associated with lower all-cause mortality [HR (95% CI) comparing the highest tertile with non-consumers: 0.77 (0.63-0.94), P trend = 0.002]. Increasing red meat consumption from before to after hypertension diagnosis was significantly associated with higher all-cause mortality [HR (95% CI): 1.55 (1.05-2.28), P trend = 0.04]. Theoretically replacing 1 ounce/day of red meat with the equivalent amount of white meat or eggs was associated with 5% and 10% lower all-cause mortality, respectively. CONCLUSIONS: High consumption of red meat, especially after hypertension diagnosis, is associated with higher mortality among hypertensive patients. Our findings suggest replacing red meat consumption with healthy alternative foods for long-term survival among hypertensive patients.


Subject(s)
Diet/mortality , Hypertension/mortality , Meat/statistics & numerical data , Aged , Cause of Death , China , Cohort Studies , Diet/methods , Diet Records , Diet Surveys , Eating , Eggs/statistics & numerical data , Female , Follow-Up Studies , Heart Disease Risk Factors , Humans , Male , Meat/adverse effects , Middle Aged , Proportional Hazards Models , Red Meat/adverse effects , Red Meat/statistics & numerical data
6.
Nutrients ; 12(12)2020 Dec 17.
Article in English | MEDLINE | ID: mdl-33348651

ABSTRACT

To our knowledge, no studies have investigated the relationship between a posteriori dietary patterns (DPs)-representing current dietary behavior-and disease activity in patients with rheumatoid arthritis (RA). We analyzed data from a recent Italian cross-sectional study including 365 RA patients (median age: 58.46 years, 78.63% females). Prevalent DPs were identified through principal component factor analysis on 33 nutrients. RA activity was measured according to the Disease Activity Score on 28 joints (DAS28) and the Simplified Disease Activity Index (SDAI). Single DPs were related to disease activity through linear and logistic regression models, adjusted for the remaining DPs and confounders. We identified five DPs (~80% variance explained). Among them, Vegetable unsaturated fatty acids (VUFA) and Animal unsaturated fatty acids (AUFA) DPs were inversely related to DAS28 in the overall analysis, and in the more severe or long-standing RA subgroups; the highest score reductions (VUFA: 0.81, AUFA: 0.71) were reached for the long-standing RA. The SDAI was inversely related with these DPs in subgroups only. This Italian study shows that scoring high on DPs based on unsaturated fats from either source provides independent beneficial effects of clinical relevance on RA disease activity, thus strengthening evidence on the topic.


Subject(s)
Arthritis, Rheumatoid/physiopathology , Diet/methods , Fatty Acids, Unsaturated/pharmacology , Meat/statistics & numerical data , Vegetables , Cross-Sectional Studies , Fatty Acids, Unsaturated/administration & dosage , Female , Humans , Italy , Male , Middle Aged , Principal Component Analysis , Reproducibility of Results , Risk Assessment , Severity of Illness Index
7.
Nutrients ; 12(6)2020 Jun 12.
Article in English | MEDLINE | ID: mdl-32545520

ABSTRACT

Eating behavior is an important aspect for dietary quality and long-term health. This study examined associations between eating vegetables first at a meal and food intakes among preschool children in Tokyo, Japan. We used cross-sectional data of 135 preschool children from seven nursery schools in Adachi City, Tokyo, Japan. Caregivers completed a survey on child's eating behaviors and a diet questionnaire. Linear regression was used to examine frequency of eating vegetables first at a meal and food intakes; percent difference and the corresponding 95% confidence interval (95% CI) were presented. Overall, 25.2% of children reported eating vegetables first at a meal every time, 52.6% sometimes, and 22.2% not often or never. In the multivariate analysis, higher vegetable intake remained significant after adjusting for other covariates (compared with the group of eating vegetables first not often or never, the group reported sometimes: 27%, 95% CI: 0-63%; the group reported every time: 93%, 95% CI: 43-159%). No significant difference in intake by frequency categories of eating vegetables first was observed for other food groups, including fruits, meat, fish, cereals, and sweets. Children eating vegetables first at a meal more was associated with higher total intake of vegetables compared with children who did not eat vegetables first, among Japanese preschool children.


Subject(s)
Child Nutritional Physiological Phenomena , Diet/statistics & numerical data , Feeding Behavior , Meals , Vegetables , Child , Child, Preschool , Cross-Sectional Studies , Diet/methods , Diet Surveys , Edible Grain , Energy Intake , Female , Fruit , Humans , Japan , Linear Models , Male , Meat/statistics & numerical data , Seafood/statistics & numerical data
8.
J Hum Nutr Diet ; 33(4): 505-517, 2020 08.
Article in English | MEDLINE | ID: mdl-32154639

ABSTRACT

INTRODUCTION: Global public health recommendations advise limiting the intake of red and processed meats. There is a need for more comprehensive information on meat consumption in Australia, specifically usual intake of meat from a nationally representative sample. The aim of this study was to use the National Cancer Institute (NCI) method to examine usual meat intakes in the 2011-12 National Nutrition and Physical Activity Survey (NNPAS). METHODS: This was a secondary analysis of the cross-sectional 2011-12 NNPAS, which contains observations for 12 153 respondents (9341 adults and 2812 children/adolescents). Usual consumption of all meat, red and processed meats was calculated using the NCI method. Consumption of meat was explored by age and gender groups, as well as by household type. RESULTS: Amongst adults and children/adolescents, consumption of all meat was significantly higher in males (adults: 187.1 g day-1 ; children/adolescents: 125.0 g day-1 ) than females (adults: 125.5 g day-1 ; children/adolescents: 95.4 g day-1 ). Similar patterns were observed for red (males: adults 85.5 g day-1 , children/adolescents 42.9 g day-1 ; females: adults 57.1 g day-1 , children/adolescents 34.9 g day-1 ) and processed meat, although intakes of processed meats in children and adolescents (males: 26.5 g day-1 ; females: 16.8 g day-1 ) were found to be similar to those of adults aged ≥19 years (males: 28.3 g day-1 ; females: 15.3 g day-1 ). Patterns of meat consumption across household types appeared to differ between genders. CONCLUSIONS: The present study suggests that Australians are likely to be exceeding population recommendations for meat intakes, with differing patterns observed across gender and household types. These findings highlight a need for targeted dietetic and population strategies aimed at promoting a healthy consumption of meats within the Australian population.


Subject(s)
Diet/statistics & numerical data , Meat/statistics & numerical data , Adolescent , Adult , Aged , Australia , Child , Child, Preschool , Cross-Sectional Studies , Diet/standards , Eating , Exercise , Family Characteristics , Female , Humans , Male , Meat/standards , Middle Aged , Nutrition Surveys , Recommended Dietary Allowances , Sex Factors , Young Adult
9.
J Anim Breed Genet ; 137(5): 438-448, 2020 Sep.
Article in English | MEDLINE | ID: mdl-32020678

ABSTRACT

The goal of this study was to compare the predictive performance of artificial neural networks (ANNs) with Bayesian ridge regression, Bayesian Lasso, Bayes A, Bayes B and Bayes Cπ in estimating genomic breeding values for meat tenderness in Nellore cattle. The animals were genotyped with the Illumina Bovine HD Bead Chip (HD, 777K from 90 samples) and the GeneSeek Genomic Profiler (GGP Indicus HD, 77K from 485 samples). The quality control for the genotypes was applied on each Chip and comprised removal of SNPs located on non-autosomal chromosomes, with minor allele frequency <5%, deviation from HWE (p < 10-6 ), and with linkage disequilibrium >0.8. The FImpute program was used for genotype imputation. Pedigree-based analyses indicated that meat tenderness is moderately heritable (0.35), indicating that it can be improved by direct selection. Prediction accuracies were very similar across the Bayesian regression models, ranging from 0.20 (Bayes A) to 0.22 (Bayes B) and 0.14 (Bayes Cπ) to 0.19 (Bayes A) for the additive and dominance effects, respectively. ANN achieved the highest accuracy (0.33) of genomic prediction of genetic merit. Even though deep neural networks are recognized to deliver more accurate predictions, in our study ANN with one single hidden layer, 105 neurons and rectified linear unit (ReLU) activation function was sufficient to increase the prediction of genetic merit for meat tenderness. These results indicate that an ANN with relatively simple architecture can provide superior genomic predictions for meat tenderness in Nellore cattle.


Subject(s)
Breeding/statistics & numerical data , Genomics/statistics & numerical data , Neural Networks, Computer , Quantitative Trait, Heritable , Animals , Bayes Theorem , Cattle , Chromosomes , Gene Frequency , Genome/genetics , Genotype , Linkage Disequilibrium/genetics , Meat/analysis , Meat/statistics & numerical data , Pedigree , Polymorphism, Single Nucleotide
10.
Int J Cancer ; 146(5): 1333-1345, 2020 03 01.
Article in English | MEDLINE | ID: mdl-31525258

ABSTRACT

The current study aimed to investigate the relationship between red and white meat subtypes, processed meat (divided into traditional "Khlii, Kaddid" and industrially processed meat) and colorectal cancer (CRC) risk, considering CRC subsites, in Moroccan adults. A case-control study was conducted including 2,906 matched case-control pairs recruited from the five largest university hospitals in Morocco. Dietary data were collected through a validated Food Frequency Questionnaire (FFQ). Multivariable odds ratios (OR) and 95% confidence intervals (CI), for the association of CRC risk with meat consumption (high vs. low intake), were estimated using conditional logistic regression models, adjusted for relevant confounding variables. Overall, consumption of red meat was positively associated with colon cancer and CRC risk (OR = 1.23, 95% CI = 1.05-1.44; OR = 1.14, 95% CI = 1.02-1.27), respectively. In contrast, no significant association was observed between the consumption of red meat and rectal cancer risk (OR = 1.05, 95% = 0.90-1.23). Interestingly, while processed meat from industrial processes was positively associated with colon cancer, rectal cancer and CRC (OR = 1.61, 95% CI = 1.27-2.04; OR = 1.73, 95% CI = 1.34-2.23; OR = 1.67, 95% CI = 1.41-1.98), processed meat prepared using traditional methods was inversely associated with colon cancer and CRC risk (OR = 0.74, 95% CI = 0.57-0.98; OR = 0.77, 95% CI = 0.64-0.93), respectively. Furthermore, positive associations were observed between poultry intake and colon cancer risk among men (OR = 1.27, 95% CI = 1.01-1.59). Our study showed similar associations between the consumption of red meat and CRC risk in Morocco as in developed countries, while inverse associations were found for traditionally processed meat products. This is the first study to investigate the differential effects of traditional vs. westernized processed meat products in a developing country. Other studies are needed to confirm these findings and to understand the physiological pathways underlying these associations.


Subject(s)
Colorectal Neoplasms/epidemiology , Meat Products/statistics & numerical data , Meat/statistics & numerical data , Animals , Case-Control Studies , Colorectal Neoplasms/etiology , Female , Humans , Logistic Models , Male , Morocco/epidemiology , Poultry , Red Meat/statistics & numerical data , Risk , Rural Population/statistics & numerical data , Urban Population/statistics & numerical data
11.
Clin Nutr ; 39(1): 242-249, 2020 01.
Article in English | MEDLINE | ID: mdl-30739809

ABSTRACT

BACKGROUND & AIMS: High protein intake has been linked to increased type 2 diabetes (T2D) risk. However, if this association differs by protein from specific food sources, and if a habitual high protein intake affects insulin resistance and prediabetes risk are largely unknown. We aimed to investigate associations between protein intake from different food sources with longitudinal insulin resistance, and risk of prediabetes and T2D. METHODS: Our analyses included 6822 participants aged ≥45 years without diabetes at baseline in three sub-cohorts of the prospective population-based Rotterdam Study. We measured protein intake at baseline using food-frequency questionnaires. Data on longitudinal homeostatic model assessment of insulin resistance (HOMA-IR), and incidence of prediabetes and T2D were available from 1993 to 2014. RESULTS: During follow-up, we documented 931 prediabetes cases and 643 T2D cases. After adjusting for sociodemographic, lifestyle, and dietary factors, higher total protein intake was associated with higher longitudinal HOMA-IR and with higher risk of prediabetes and T2D (per 5% increment in energy from protein at the expense of carbohydrate, for HOMA-IR: ß = 0.10, (95%CI 0.07, 0.12); for prediabetes: HR = 1.34 (1.24 1.44); for T2D: HR = 1.37 (1.26, 1.49)). These associations were mainly driven by total animal protein (for HOMA-IR: 0.10 (0.07, 0.12); for prediabetes: 1.35 (1.24, 1.45); for T2D: 1.37 (1.26; 1.49)). The harmful associations of total animal protein were contributed to by protein from meat, fish, and dairy (e.g. for HOMA-IR: protein from meat, 0.13 (0.10, 0.17); from fish, 0.08 (0.03, 0.13); from dairy, 0.04 (0.0003, 0.08)). After additional adjustment for longitudinal waist circumference, associations of total protein and total animal protein with longitudinal HOMA-IR and prediabetes risk were attenuated, but remained statistically significant. Total plant protein, as well as protein from legumes and nuts, from grains, from potatoes, or from fruits and vegetables, was not associated with any of the outcomes. CONCLUSIONS: Higher intake of animal protein, from meat, dairy and fish food sources, is associated with higher longitudinal insulin resistance and risk of prediabetes and T2D, which may be partly mediated by obesity over time. Furthermore, plant protein from different sources is not related to insulin resistance, and risk of prediabetes and T2D. Our findings highlight the importance of specific protein food sources and that habitual high animal protein intake may already in early stages be harmful in the development of T2D.


Subject(s)
Dairy Products/statistics & numerical data , Diabetes Mellitus, Type 2/epidemiology , Dietary Proteins/administration & dosage , Insulin Resistance , Meat/statistics & numerical data , Prediabetic State/epidemiology , Seafood/statistics & numerical data , Aged , Diet Records , Female , Follow-Up Studies , Humans , Incidence , Longitudinal Studies , Male , Middle Aged , Netherlands/epidemiology
12.
Int J Cancer ; 146(8): 2156-2165, 2020 04 15.
Article in English | MEDLINE | ID: mdl-31389007

ABSTRACT

Meat consumption has been postulated to increase the risk of breast cancer, but this association has not been consistently seen. We examined the association between consumption of different types of meat, meat mutagens and incident invasive breast cancer. Information on consumption of different meat categories and meat cooking practice behaviors was obtained from 42,012 Sister Study participants who completed a Block 1998 Food Frequency Questionnaire at enrollment (2003-2009) and satisfied eligibility criteria. Exposure to meat type and meat mutagens was calculated, and associations with invasive breast cancer risk were estimated using multivariable Cox proportional hazards regression. During follow-up (mean, 7.6 years), 1,536 invasive breast cancers were diagnosed at least 1 year after enrollment. Increasing consumption of red meat was associated with increased risk of invasive breast cancer (HRhighest vs. lowest quartile :1.23, 95% CI: 1.02-1.48, ptrend = 0.01). Conversely, increasing consumption of poultry was associated with decreased invasive breast cancer risk (HR highest vs. lowest quartile : 0.85; 95% CI: 0.72-1.00; ptrend = 0.03). In a substitution model with combined red meat and poultry consumption held constant, substituting poultry for red meat was associated with decreased invasive breast cancer risk (HR highest vs. lowest quartile of poultry consumption: 0.72, 95% CI: 0.58-0.89). No associations were observed for cooking practices, estimated heterocyclic amines or heme iron from red meat consumption with breast cancer risk. Red meat consumption may increase the risk of invasive breast cancer, whereas poultry consumption may be associated with reduced risk. Substituting poultry for red meat could reduce breast cancer risk.


Subject(s)
Breast Neoplasms/epidemiology , Meat/statistics & numerical data , Animals , Cooking/methods , Cooking/statistics & numerical data , Female , Humans , Middle Aged , Poultry , Proportional Hazards Models , Puerto Rico/epidemiology , Red Meat/statistics & numerical data
13.
J Ren Nutr ; 30(2): 111-118, 2020 03.
Article in English | MEDLINE | ID: mdl-31422013

ABSTRACT

OBJECTIVE: The aim of the present study was to investigate the association of different meat intake and substitution of them with risk of incident chronic kidney disease (CKD). METHODS: At the baseline, habitual dietary intakes of 4881 participants of the Tehran Lipid and Glucose Study who were free of CKD were assessed by a valid and reliable food-frequency questionnaire. Logistic regression, adjusted for age, sex, smoking, total energy intake, triglycerides, body mass index, physical activity, hypertension, and diabetes, was used to assess the relationship between major protein sources of food (total red meat, unprocessed red meat, and processed red meat) and incident CKD. Odds ratios (ORs) and 95% confidence intervals (CIs) for the CKD were estimated for substituting one serving of total red meat with one serving of low-fat dairy, nuts, whole grains, and legumes. RESULTS: The mean ± standard deviation age of participants was 40.1 ± 12.8 years. After adjustment for confounders, compared with the lowest quartile of total red meat intake, OR of incident CKD in the highest quartile was 1.73 (95% CI: 1.33 to 2.24; P for trend <0.001) in the final model. OR for participants in the highest compared with that in the lowest quartile of processed red meat was 1.99 (95% CI: 2.54 to 2.56; P for trend <0.001). In the substitution analyses, replacing 1 serving of total red meat and processed meat with 1 serving of low-fat dairy, nuts, whole grains, and legumes was associated with a lower risk of incident CKD. CONCLUSIONS: Higher consumption of total red meat and processed meat was associated with increased risk of incident CKD. Furthermore, substitution of total red and processed meat in the diet with other sources of dietary protein was associated with lower CKD risk.


Subject(s)
Diet/adverse effects , Diet/methods , Meat/statistics & numerical data , Renal Insufficiency, Chronic/epidemiology , Adult , Female , Humans , Iran/epidemiology , Male , Middle Aged , Prospective Studies , Risk Factors
14.
Public Health Nutr ; 23(2): 319-328, 2020 02.
Article in English | MEDLINE | ID: mdl-31397262

ABSTRACT

OBJECTIVE: To investigate the association between dietary patterns (DP) and overweight risk in the Malaysian Adult Nutrition Surveys (MANS) of 2003 and 2014. DESIGN: DP were derived from the MANS FFQ using principal component analysis. The cross-sectional association of the derived DP with prevalence of overweight was analysed. SETTING: Malaysia. PARTICIPANTS: Nationally representative sample of Malaysian adults from MANS (2003, n 6928; 2014, n 3000). RESULTS: Three major DP were identified for both years. These were 'Traditional' (fish, eggs, local cakes), 'Western' (fast foods, meat, carbonated beverages) and 'Mixed' (ready-to-eat cereals, bread, vegetables). A fourth DP was generated in 2003, 'Flatbread & Beverages' (flatbread, creamer, malted beverages), and 2014, 'Noodles & Meat' (noodles, meat, eggs). These DP accounted for 25·6 and 26·6 % of DP variations in 2003 and 2014, respectively. For both years, Traditional DP was significantly associated with rural households, lower income, men and Malay ethnicity, while Western DP was associated with younger age and higher income. Mixed DP was positively associated with women and higher income. None of the DP showed positive association with overweight risk, except for reduced adjusted odds of overweight with adherence to Traditional DP in 2003. CONCLUSIONS: Overweight could not be attributed to adherence to a single dietary pattern among Malaysian adults. This may be due to the constantly morphing dietary landscape in Malaysia, especially in urban areas, given the ease of availability and relative affordability of multi-ethnic and international foods. Timely surveys are recommended to monitor implications of these changes.


Subject(s)
Diet/statistics & numerical data , Feeding Behavior , Obesity/epidemiology , Overweight/epidemiology , Adolescent , Adult , Body Mass Index , Carbonated Beverages/statistics & numerical data , Cross-Sectional Studies , Diet, Western/statistics & numerical data , Female , Humans , Income , Malaysia/epidemiology , Male , Meat/statistics & numerical data , Middle Aged , Nutrition Surveys , Risk Factors , Rural Population , Vegetables , Young Adult
15.
Int J Cancer ; 147(1): 45-55, 2020 07 01.
Article in English | MEDLINE | ID: mdl-31584199

ABSTRACT

The consumption of processed meat has been associated with noncardia gastric cancer, but evidence regarding a possible role of red meat is more limited. Our study aims to quantify the association between meat consumption, namely white, red and processed meat, and the risk of gastric cancer, through individual participant data meta-analysis of studies participating in the "Stomach cancer Pooling (StoP) Project". Data from 22 studies, including 11,443 cases and 28,029 controls, were used. Study-specific odds ratios (ORs) were pooled through a two-stage approach based on random-effects models. An exposure-response relationship was modeled, using one and two-order fractional polynomials, to evaluate the possible nonlinear association between meat intake and gastric cancer. An increased risk of gastric cancer was observed for the consumption of all types of meat (highest vs. lowest tertile), which was statistically significant for red (OR: 1.24; 95% CI: 1.00-1.53), processed (OR: 1.23; 95% CI: 1.06-1.43) and total meat (OR: 1.30; 95% CI: 1.09-1.55). Exposure-response analyses showed an increasing risk of gastric cancer with increasing consumption of both processed and red meat, with the highest OR being observed for an intake of 150 g/day of red meat (OR: 1.85; 95% CI: 1.56-2.20). This work provides robust evidence on the relation between the consumption of different types of meat and gastric cancer. Adherence to dietary recommendations to reduce meat consumption may contribute to a reduction in the burden of gastric cancer.


Subject(s)
Meat/statistics & numerical data , Stomach Neoplasms/epidemiology , Adult , Aged , Case-Control Studies , Cohort Studies , Diet/adverse effects , Diet/statistics & numerical data , Female , Humans , Male , Meat Products/adverse effects , Meat Products/statistics & numerical data , Middle Aged , Red Meat/adverse effects , Red Meat/statistics & numerical data , Stomach Neoplasms/etiology
16.
Animal ; 14(3): 626-635, 2020 Mar.
Article in English | MEDLINE | ID: mdl-31608861

ABSTRACT

In rabbit farms, quantitative feed restriction in the post-weaning period is widely used with the aim of reducing the impact of digestive diseases, whereas less information is available about feed restriction strategies based on the reduction of access time to feeders in different housing systems. This study compared morbidity, mortality, growth performance, carcass characteristics and meat quality of 368 crossbred rabbits fed ad libitum (L) or subjected to a time-based feed restriction programme (R) and housed from 31 to 73 days of age in cages or pens with different dimensions and group sizes, that is, eight conventional cages (0.33 m2, six rabbits/cage), eight small open-top pens (0.50 m2, eight rabbits/pen), eight medium open-top pens (1.00 m2, 16 rabbits/pen) and four large open-top pens (2.00 m2, 32 rabbits/pen). Feed restriction was attained by progressively reducing the access time to feeders in the 1st week from 14 to 8 h/day, maintaining 8 h in the 2nd week and then by increasing access time by 1 h/day during the 3rd and 4th week up to 24 h/day. In the first 2 weeks, R rabbits showed a lower (P ≤ 0.001) daily weight gain, feed intake and feed conversion as compared with L rabbits. During the 3rd and 4th weeks, R rabbits exhibited a greater daily weight gain and better feed conversion (P ≤ 0.001). In the last 2 weeks of trial, daily weight gain tended (P = 0.06) to be greater in the R than L rabbits. In the whole trial, R rabbits manifested a lower daily weight gain, feed intake and feed conversion, as well as lower final live weight and the carcass dressing percentage at slaughter (0.05 ≤ P ≤ 0.01). During feed restriction, R rabbits did not show digestive problems, which, however, appeared in the following 2 weeks of refeeding. Thus, R rabbits had a higher health risk index in the whole trial as compared with L rabbits (P ≤ 0.05). The housing system did not affect growth performance, characteristics at slaughter, and carcass and meat quality. Mortality tended to increase with group size (P = 0.06). In conclusion, the time-based feed restriction significantly improved feed efficiency of growing rabbits housed collectively but had somewhat negative effects on characteristics at slaughter and on morbidity and mortality rate.


Subject(s)
Feeding Behavior , Meat/statistics & numerical data , Rabbits/physiology , Animal Feed/analysis , Animals , Female , Housing, Animal , Male , Morbidity , Mortality , Rabbits/growth & development , Time Factors , Weaning , Weight Gain
17.
Am J Mens Health ; 13(6): 1557988319885561, 2019.
Article in English | MEDLINE | ID: mdl-31694460

ABSTRACT

Food choice is complex and influenced by a range of social, environmental, structural, and individual factors. Poor diet is one of the major contributors to the burden of disease, in particular for men who habitually have lower intakes of fruits and vegetables and higher intakes of meat. Food choice has been linked to the expression of masculine identities. This research used a Bourdieusian framework to explore the influential drivers of young Australian men's eating habits based on occupational groupings. Twenty men aged 19-30 years participated in in-depth semistructured interviews. Analysis used a grounded theory, social constructivist approach and identified five themes: performative masculinities and meat; meat cuts across social class; the influence of masculine autonomy on dietary choice; women protecting Australian men's health; and the role of environmental and structural barriers. These results indicated that habitus remains a useful conceptual framework to explain the results, and cultural capital is reinforced as a phenomenon. Occupation and gender appear to no longer be primary drivers of food choice in this group of men. Rather there is a shift toward an understanding of multiple masculinities and the development of microcultures with interactions between structure and agency. Meat still features in the food world of Australian men, but there are shifts to deprioritize its importance. There needs to be a more nuanced understanding of the importance of autonomy and control as well as the role of women in relation to men's dietary intakes and how this can be harnessed for positive dietary change.


Subject(s)
Feeding Behavior/psychology , Gender Identity , Meat/statistics & numerical data , Men's Health , Social Class , Surveys and Questionnaires , Adult , Australia , Cultural Characteristics , Diet , Humans , Male , Masculinity , Occupations , Qualitative Research , Young Adult
18.
Trop Anim Health Prod ; 51(8): 2405-2412, 2019 Nov.
Article in English | MEDLINE | ID: mdl-31183800

ABSTRACT

Carcass performance of 12 fattened male buffalo calves equally grouped by slaughter weights of 300, 350, 400, and 450 kg was evaluated. Six parameters of body measurements such as chest girth, height at withers, body length, body depth, width at pin bones, and diagonal body length were recorded for each calf immediately before slaughter to test their relationships with live body weight, carcass weight (hot and cold) and its components (head, legs, liver, heart, etc.), and eye muscle area at the 10th-13th ribs. Boneless meat and bones formed 36.6 to 39.0% and 9.3 to 11.0% of live weight, respectively. Chest girth had strong correlation with all carcass traits except bone weight and was the best predictor of boneless meat and carcass fat weights (R2 = 0.90, 0.78). The slaughter weight and height at withers and the 10th-13th rib fat weight were the best predictors of hot and cold carcass (R2 ≥ 97.0), carcass bones (R2 = 76%), and hot and cold carcass (R2 = 85.0, 86.5%) weights, respectively.


Subject(s)
Body Composition , Body Weight , Buffaloes/anatomy & histology , Meat/statistics & numerical data , Adipose Tissue , Animals , Bone and Bones , Egypt , Male , Muscles/anatomy & histology , Phenotype
20.
Asia Pac J Clin Nutr ; 28(2): 276-284, 2019.
Article in English | MEDLINE | ID: mdl-31192557

ABSTRACT

BACKGROUND AND OBJECTIVES: Information about an association between animal food intakes and risk of anemia is still limited. This study aimed to investigate the association between fish and meat intake and anemia risk in the Japanese elderly. METHODS AND STUDY DESIGN: A nationally representative sample of 6,469 aged 65 years and over was obtained from pooled data of annual National Health and Nutritional Survey in Japan during 2002-2011. Anemia was defined as hemoglobin concentrations <13.0 g/dL in males and <12.0 g/dL in females. Logistic regression analysis, with the lowest intake tertile as the reference, was applied to estimate anemia risk for each nutrient and food group. RESULTS: After adjustment for putative confounding factors, males in the highest tertile of animal protein intake had significantly lower risk of anemia than those in the lowest tertile (odds ratio (OR): 0.77; 95% confidence interval (CI): 0.63, 0.95; p for trend=0.017). These associations were not seen in females (OR: 0.72, 95% CI: 0.49, 1.06; p for trend=0.100). Multivariate analyses revealed that anemia risk (OR: 0.80; 95% CI: 0.65, 0.97; p for trend =0.002) was lower for males in the highest tertile of fish intake than in the lowest tertile; this effect was also observed for females (OR: 0.64; 95% CI: 0.45, 0.92; p for trend =0.014). In both sexes, the highest tertile of meat intake was not associated with lower anemia risk in the multivariate-adjusted models. CONCLUSIONS: The current cross-sectional study in Japanese elderly males suggests that higher animal protein, specifically the high protein content of fish may be associated with a lower prevalence of anemia.


Subject(s)
Anemia/epidemiology , Geriatric Assessment/methods , Health Surveys/statistics & numerical data , Meat/statistics & numerical data , Seafood/statistics & numerical data , Aged , Aged, 80 and over , Cross-Sectional Studies , Female , Geriatric Assessment/statistics & numerical data , Health Surveys/methods , Humans , Japan/epidemiology , Male , Prevalence , Risk Factors
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