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1.
Acta Orthop Belg ; 82(4): 866-871, 2016 Dec.
Article in English | MEDLINE | ID: mdl-29182131

ABSTRACT

We compared results of lateral pinning procedure with crossed pinning, closed reduction, and open reduction in a retrospective review of 184 patients with displaced supracondylar humeral fractures. All patients had a minimum of 2 years follow-up (range 36-90 months). Patients were separated into 4 groups. Success was estimated by Flynn's criteria. We compared success of the lateral pinning to others procedures. Incidence of nerve palsy was recorded and compared. Esthetic effect of lateral pinning is significantly better than closed reduction (p=0.0007), but no significant difference was found comparing with cross pinning and open reduction. Elbow function was similar. Cross pinning procedure was followed with ulnar nerve palsy in ten patients (20.8%). There was 1 case (5%) of combined nerve palsy including ulnar, median and radial nerve after open reduction procedure. Lateral pinning is safe and effective method of therapy for Gartland type II and III supracondylar humeral fractures.


Subject(s)
Bone Nails , Elbow Injuries , Fracture Fixation, Internal/methods , Humeral Fractures/surgery , Peripheral Nervous System Diseases/epidemiology , Postoperative Complications/epidemiology , Adolescent , Child , Child, Preschool , Closed Fracture Reduction/methods , Elbow Joint/surgery , Female , Humans , Incidence , Male , Median Neuropathy/epidemiology , Open Fracture Reduction/methods , Radial Neuropathy/epidemiology , Retrospective Studies , Ulnar Neuropathies/epidemiology
2.
Diabetes Metab Res Rev ; 31(4): 385-94, 2015 May.
Article in English | MEDLINE | ID: mdl-25417846

ABSTRACT

BACKGROUND: To understand the impacts of disease chronicity and hyperglycaemia on sensorimotor control of hands of diabetic patients, this study investigated the differences in hand sensation, strength and motor control by applying the pinch-holding-up activity test for patients with diabetes mellitus (DM) with different levels of glycaemic control and disease chronicity. METHODS: One hundred and fifty-nine patients with clinically defined DM were included. Semmes-Weinstein monofilament, static two-point discrimination and moving two-point discrimination, maximal pinch strength precision pinch performance tests and nerve conduction studies (NCS) of the subjects were carried out. Forty-seven (29.6%) patients were in the HbA(1c) < 7% category, and 112 (70.4%) patients were in the >7% group. There were 87 (54.7%) patients with the disease duration <10 years, and 72 (45.3%) patients with disease duration ≧10 years. RESULTS: The severity of hyperglycaemia significantly impacts the results for Semmes-Weinstein monofilament, precision pinch force control, sensory and motor NCS tests (p < 0.05). In addition, the chronicity of disease influences the motor control of precision pinch performance and the amplitude of motor NCS (p < 0.05) for the diabetes patients. CONCLUSIONS: The evidence suggests that disease chronicity and hyperglycaemia have impacts on sensorimotor control in the hands of DM patients. In addition, the efficiency of prehensile forces of hand-to-object interactions in the pinch-holding-up activity test could be significant for identifying hand function, as well as pathologic changes in median nerve function, for patients with DM.


Subject(s)
Diabetic Neuropathies/blood , Feedback, Sensory , Glycated Hemoglobin/analysis , Hyperglycemia/etiology , Median Neuropathy/complications , Up-Regulation , Aged , Diabetes Mellitus/physiopathology , Diabetes Mellitus/therapy , Diabetic Neuropathies/epidemiology , Diabetic Neuropathies/physiopathology , Female , Hand , Hand Strength , Humans , Hyperglycemia/physiopathology , Male , Median Neuropathy/blood , Median Neuropathy/epidemiology , Median Neuropathy/physiopathology , Middle Aged , Motor Skills , Neural Conduction , Pinch Strength , Prospective Studies , Risk Factors , Severity of Illness Index , Taiwan/epidemiology
3.
Muscle Nerve ; 51(2): 201-6, 2015 Feb.
Article in English | MEDLINE | ID: mdl-24829063

ABSTRACT

INTRODUCTION: We evaluated the electrodiagnostic (EDX) pattern of severe and extreme median nerve lesions at the wrist (MNLW) in patients with idiopathic carpal tunnel syndrome. METHODS: EDX data were recorded in 229 patients with 314 severe and extreme MNLW and 447 patients with 777 non-severe MNLW. We recorded distal motor latency (DML) to abductor pollicis brevis (APB) and second lumbricalis (2L), sensory conduction (SC) from digits 2 and 3, and needle examination of APB. RESULTS: Preservation rate of DML to APB and 2L and of SC from digits 2 and 3 were 100%, 100%, 85%, and 76%, respectively, for severe MNLW, and 37%, 90%, 36%, and 26% for extreme MNLW. Active denervation, as demonstrated by fibrillation potentials, was found in 1% of non-severe NMLW, 7% of severe MNLW, and 56% of extreme MNLW cases. CONCLUSIONS: In idiopathic severe and extreme MNLW, the DML to the 2L and averaged SC from digit 2 can be present when other responses are absent.


Subject(s)
Electrodiagnosis , Median Neuropathy/diagnosis , Median Neuropathy/physiopathology , Neural Conduction/physiology , Wrist/innervation , Action Potentials/physiology , Adult , Aged , Analysis of Variance , Female , Humans , Male , Median Neuropathy/epidemiology , Middle Aged , Reaction Time , Retrospective Studies , Severity of Illness Index
4.
Muscle Nerve ; 48(4): 539-44, 2013 Oct.
Article in English | MEDLINE | ID: mdl-24037717

ABSTRACT

INTRODUCTION: The prevalence of bifid median nerves and persistent median arteries, their co-occurrence, and their relationship to carpal tunnel syndrome (CTS) are only understood partially. METHODS: We screened 1026 wrists of 513 Latino manual laborers in North Carolina for bifid median nerves and persistent median arteries using electrodiagnosis and ultrasound. RESULTS: A total of 8.6% of wrists had a bifid median nerve, and 3.7% of wrists had a persistent median artery independent of subgroup ethnicity, age, gender, or type of work. An association with definite carpal tunnel syndrome was not found. The presence of either anatomic variant was associated with a high likelihood of co-occurrence of another variant in the same or the contralateral wrist. CONCLUSIONS: The occurrence of median anatomic variants can be determined in field studies using ultrasound. Persistent median arteries and bifid median nerves tend to co-occur but do not put manual laborers at additional risk of developing CTS.


Subject(s)
Brachial Artery/diagnostic imaging , Carpal Tunnel Syndrome/diagnosis , Median Neuropathy/diagnosis , Occupational Diseases/diagnosis , Peripheral Arterial Disease/diagnostic imaging , Adult , Carpal Tunnel Syndrome/epidemiology , Female , Food Industry , Hispanic or Latino , Humans , Male , Median Neuropathy/diagnostic imaging , Median Neuropathy/epidemiology , Middle Aged , North Carolina/epidemiology , Occupational Diseases/diagnostic imaging , Occupational Diseases/epidemiology , Peripheral Arterial Disease/epidemiology , Prevalence , Ultrasonography , Workforce
5.
Arch Orthop Trauma Surg ; 133(9): 1321-7, 2013 Sep.
Article in English | MEDLINE | ID: mdl-23864157

ABSTRACT

PURPOSE: Irritation of the median nerve is a well-characterized complication after acute fractures of the distal radius, but there is limited literature on median neuropathy in malunited fractures. The aims of our prospective study were to estimate the prevalence of the median neuropathy, explore the relationship between radiographic findings and the condition, and investigate whether corrective osteotomy without carpal tunnel release was a sufficient treatment. METHODS: Thirty consecutive patients, who were referred to us for treatment of symptomatic distal radial malunion, underwent nerve conduction studies of both wrists by one board-certified neurologist under standardized conditions. Test results were correlated with conventional radiographic parameters (radial tilt, radial inclination, palmar shift, ulnar variance, radiolunate and capitolunate angle) and computer tomography (CT) based measurements of the cross-sectional area of the carpal tunnel. After corrective osteotomy without carpal tunnel release, 10 of 13 patients with unilateral preoperative median neuropathy agreed to an electrodiagnostic re-examination by the same neurologist. RESULTS: Nineteen patients demonstrated abnormal test results, but only seven patients complained about paresthesias of median-innervated fingers. There was no correlation between median neuropathy and conventional radiographic parameters. Surprisingly, the cross-sectional area of the carpal canal was significantly greater for patients with median neuropathy. Symptoms resolved in all patients after corrective osteotomy. Postoperatively, six of ten patients demonstrated improved nerve conduction studies, although only four patients demonstrated normal test results. DISCUSSION: There is a high rate of subclinical median neuropathy in malunited distal radial fractures that cannot be predicted by conventional radiographic parameters. Corrective osteotomy without carpal tunnel release is a sufficient treatment for neuropathy in malunited distal radius fractures.


Subject(s)
Fractures, Malunited/complications , Median Neuropathy/etiology , Radius/injuries , Wrist Injuries/complications , Adolescent , Adult , Aged , Female , Humans , Male , Median Neuropathy/diagnosis , Median Neuropathy/epidemiology , Median Neuropathy/surgery , Middle Aged , Osteotomy , Prevalence , Prospective Studies , Young Adult
6.
Joint Bone Spine ; 80(6): 632-7, 2013 Dec.
Article in English | MEDLINE | ID: mdl-23566665

ABSTRACT

OBJECTIVE: To evaluate the relationship among obesity, incidence of idiopathic median nerve lesion at the wrist (MNLW), idiopathic severe MNLW and diabetes mellitus type 2 (DMT2)-associated severe MNLW. METHODS: Clinical and electrodiagnostic data were prospectively collected from 676 patients (≥20 years, 76% females) with carpal tunnel syndrome who were referred to our electrodiagnostic laboratories. In total, 229 patients had 314 cases of severe idiopathic MNLW, 447 had 777 cases of idiopathic non-severe MNLW, and 43 DMT2 patients had 62 cases of severe MNLW. We computed the standardized prevalence ratio (SPR) for obesity and compared the prevalence of obesity and body mass index (BMI) in patients with idiopathic MNLW and the 2009 OBesity EPIdemilogic (OBEPI) sample representing the prevalence of obesity in 24,455 French adults. We compared the prevalence of obesity in DMT2 patients and the Échantillon national témoin représentatif des personnes diabétiques (ENTRED) sample representing the prevalence of cardiovascular risk factors, including obesity, in 3894 French patients with DMT2. RESULTS: The SPR for obesity was 1.60 (95% confidence interval 1.23-2.07) for idiopathic severe MNLW as compared with the OBEPI sample, and 1.72 (1.17-2.46) for DMT2-associated severe MNLW as compared with the ENTRED sample. The risk of severe MNLW increased with BMI: the adjusted odds ratio was 1.09 (1.05-1.13) for each 1-point increase in BMI. This risk was not significant for patients 60 years and older. DISCUSSION: The prevalence of obesity is increased for patients with severe MNLW and DMT2-associated severe MNLW as compared with their respective general populations.


Subject(s)
Diabetes Mellitus, Type 2/epidemiology , Median Neuropathy/epidemiology , Obesity/epidemiology , Adult , Aged , Carpal Tunnel Syndrome/diagnosis , Carpal Tunnel Syndrome/epidemiology , Carpal Tunnel Syndrome/etiology , Diabetes Mellitus, Type 2/etiology , Female , Humans , Male , Median Neuropathy/diagnosis , Median Neuropathy/etiology , Middle Aged , Prevalence , Risk Factors , Wrist
7.
US Army Med Dep J ; : 72-81, 2012.
Article in English | MEDLINE | ID: mdl-22815168

ABSTRACT

PURPOSE/HYPOTHESIS: Dental personnel including dentists, dental hygienists, and dental assistants have been reported as having a high prevalence of upper-extremity musculoskeletal disorders, including carpal tunnel syndrome. Previous research has not involved dental assistant students at the onset of dental training. Therefore, the purpose of this study was to determine the presence of median and ulnar neuropathies in US Army dental assistants at the onset of their training. NUMBER OF SUBJECTS: Fifty-five US Army Soldiers (28 female, 27 male) enrolled in the Dental Assistant (68E) course, volunteered to participate in the study. The mean age of the dental assistant students was 24±7.2 years (range 18-41 years). There were 45 right handed dental assistant students, and the mean length of time in the Army prior to dental training was 27 months (range 3-180 months). MATERIALS/METHODS: Subjects were evaluated during the first week of their 10-week dental assistant course. Subjects completed a history form, were interviewed, and underwent a physical examination. Electrophysiological status of the median and ulnar nerves of both upper extremities was obtained by performing motor and sensory nerve conduction studies. Descriptive statistics for subject demographics and nerve conduction study variables were calculated. RESULTS: Six of the 55 subjects (11%) presented with abnormal electrophysiologic values suggestive of median mononeuropathy at or distal to the wrist. Five of the subjects had abnormal electrophysiologic values in both hands. Five of these 6 subjects had clinical examination findings consistent with the electrophysiological findings. The ulnar nerve electrophysiologic assessment was normal in all subjects sampled. CONCLUSIONS: The prevalence of median mononeuropathies in this sample of Army dental assistants at the onset of training is greater than 5% prevalence reported in previous healthy populations and is less than 26% prevalence in previous research examining Army dental assistants with dental work experience. CLINICAL RELEVANCE: Median neuropathy at or distal to the wrist has been reported in dental personnel including dentists, dental hygienists, and dental assistants, and is also prevalent in this sample of dental assistants at the onset of training. Further long-term prospective research involving the impact of dental practice and techniques for reducing upper extremity injuries in dental professionals appears to be warranted.


Subject(s)
Dental Assistants , Median Neuropathy/epidemiology , Military Personnel , Occupational Diseases/epidemiology , Ulnar Neuropathies/epidemiology , Adult , Dental Assistants/statistics & numerical data , Electrodiagnosis , Female , Humans , Male , Median Nerve/physiopathology , Military Personnel/statistics & numerical data , Neural Conduction , Physical Examination , Ulnar Nerve/physiopathology , United States , Young Adult
8.
Diabetes Care ; 33(5): 1090-6, 2010 May.
Article in English | MEDLINE | ID: mdl-20150297

ABSTRACT

OBJECTIVE: To evaluate the impact of former intensive versus conventional insulin treatment on neuropathy in Diabetes Control and Complications Trial (DCCT) intensive and conventional treatment subjects with type 1 diabetes 13-14 years after DCCT closeout, during which time the two groups had achieved similar A1C levels. RESEARCH DESIGN AND METHODS: Clinical and nerve conduction studies (NCSs) performed during the DCCT were repeated during the Epidemiology of Diabetes Interventions and Complications (EDIC) study by examiners masked to treatment status on 603 former intensive and 583 former conventional treatment subjects. Clinical neuropathy was defined by symptoms, sensory signs, or reflex changes consistent with distal polyneuropathy and confirmed with NCS abnormalities involving two or more nerves among the median, peroneal, and sural nerves. RESULTS: The prevalence of neuropathy increased 13-14 years after DCCT closeout from 9 to 25% in former intensive and from 17 to 35% in former conventional treatment groups, but the difference between groups remained significant (P < 0.001), and the incidence of neuropathy remained lower among former intensive (22%) than former conventional (28%) treatment subjects (P = 0.0125). Analytic models of incident neuropathy that adjusted for differences in NCS results at DCCT closeout showed no significant risk reduction associated with former intensive treatment during follow-up (odds ratio 1.17 [95% CI 0.84-1.63]). However, a significant persistent treatment group effect was observed for several NCS measures. Longitudinal analyses of overall glycemic control showed a significant association between mean A1C and measures of incident and prevalent neuropathy. CONCLUSIONS: The benefits of former intensive insulin treatment persisted for 13-14 years after DCCT closeout and provide evidence of a durable effect of prior intensive treatment on neuropathy.


Subject(s)
Diabetes Mellitus, Type 1/drug therapy , Diabetes Mellitus, Type 1/epidemiology , Diabetic Neuropathies/epidemiology , Insulin/administration & dosage , Randomized Controlled Trials as Topic , Diabetic Neuropathies/diagnosis , Follow-Up Studies , Glycated Hemoglobin/metabolism , Hyperglycemia/drug therapy , Hyperglycemia/epidemiology , Hypoglycemic Agents/administration & dosage , Incidence , Median Neuropathy/diagnosis , Median Neuropathy/epidemiology , Neural Conduction , Outcome Assessment, Health Care , Peroneal Neuropathies/diagnosis , Peroneal Neuropathies/epidemiology , Prevalence
9.
J Orthop Sports Phys Ther ; 39(9): 693-701, 2009 Sep.
Article in English | MEDLINE | ID: mdl-19721216

ABSTRACT

STUDY DESIGN: Descriptive. OBJECTIVES: To determine the presence of clinical and electrodiagnostic abnormalities of the median and ulnar nerves in both upper extremities of dental assistants. BACKGROUND: A high prevalence of median neuropathies at, or distal to, the wrist have been reported in dentists and dental hygienists. But there is a paucity of literature on the incidence of abnormalities of the median or ulnar nerves in dental assistants. METHODS: Thirty-five United States Army dental assistants (24 female, 11 male; age range, 18-41 years) volunteered for the study. Subjects completed a standardized history and physical examination. Nerve conduction status of the median and ulnar nerves of both upper extremities was obtained by performing motor, sensory, and F-wave (central) nerve conduction studies. RESULTS: All electrophysiological variables were normal for motor, sensory, and F-wave (central) values when compared to a chart of normal values. Based on comparison studies of median and ulnar motor latencies within the same hand, 9 subjects (26%) involving 14 hands (20%) were found to have electrodiagnostic abnormalities of the median nerve at, or distal to, the wrist. The other 26 dental assistants demonstrated normal comparison studies of the median and ulnar nerves in both upper extremities. CONCLUSIONS: In this descriptive study of 35 dental assistants, 9 subjects (26%) were found to have electrodiagnostic abnormalities of the median nerve at, or distal to, the wrist (when compared to the ulnar nerve of the same hand). Ulnar nerve electrophysiological function was within normal limits for all subjects examined.


Subject(s)
Dental Assistants/statistics & numerical data , Median Neuropathy/diagnosis , Median Neuropathy/epidemiology , Military Personnel/statistics & numerical data , Ulnar Neuropathies/diagnosis , Ulnar Neuropathies/epidemiology , Adolescent , Adult , Cohort Studies , Electromyography , Female , Humans , Male , Neural Conduction/physiology , Prevalence , Reaction Time , United States , Young Adult
10.
J Neurol Sci ; 278(1-2): 41-3, 2009 Mar 15.
Article in English | MEDLINE | ID: mdl-19059612

ABSTRACT

BACKGROUND: Asymptomatic median mononeuropathy (AMM) and diabetic polyneuropathy (DPN) often coexist and can be difficult to distinguish electrophysiologically. Moreover, the potential association between AMM and DPN has not been extensively evaluated. OBJECTIVE: We investigated the relation between AMM and DPN severity in consecutive diabetic patients. METHODS: The non-dominant limb was studied electrophysiologically in 100 consecutive diabetic patients with no symptoms of carpal tunnel syndrome on the non-dominant side. AMM was diagnosed based on previously validated electrophysiological criteria. DPN severity was graded according to the Michigan diabetic neuropathy score. RESULTS: AMM was discovered in 28% of the study population (Adjusted Wald 95% CI: 20%-37%). It was more common in women, displayed a tendency of being more common in patients over 50 years old and correlated with the severity of DPN and the number of abnormal nerves on nerve conduction studies. It was present in 18.1% of patients without evidence of DPN. No correlation was found with the duration and type of diabetes. In multivariate logistic regression models increasing severity of DPN was independently associated with the presence AMM (Wald test=10.557, df=3, p=0.014). Patients with DPN stage III and IV had a five-fold (OR=5.06, 95% CI=1.49-17.19) and a four-fold (OR=4.50, 95% CI=1.15-17.65) respectively increased likelihood to present with AMM in comparison to DPN stage I (reference group). CONCLUSIONS: Our results confirmed the high incidence of AMM in diabetic patients. AMM was present in a significant number of patients in the absence of DPN and the likelihood of AMM detection increased with increasing severity of DPN.


Subject(s)
Diabetic Neuropathies/epidemiology , Median Neuropathy/epidemiology , Adult , Age Factors , Aged , Female , Humans , Incidence , Logistic Models , Male , Middle Aged , Neural Conduction , Severity of Illness Index , Sex Factors
11.
J Occup Environ Med ; 50(12): 1355-64, 2008 Dec.
Article in English | MEDLINE | ID: mdl-19092490

ABSTRACT

OBJECTIVE: To assess whether work-related physical activities are associated with Carpal tunnel syndrome (CTS), even when controlling for personal risk factors. METHODS: A cross-sectional assessment of 1108 workers from eight employers and three unions completed nerve conduction testing, physical examination, and questionnaires. CTS was defined by median neuropathy and associated symptoms. RESULTS: Eighteen workers had CTS and 131 had evidence of median neuropathy. CTS was highest among construction workers (3.0%) compared to other subjects (<1%). Logistic regression models for median neuropathy both personal and work-related risk factors. Work-related exposures were estimated by two methods: self-report and job title based ratings. CONCLUSIONS: Both work and personal factors mediated median nerve impairment. Construction workers are at an increased risk of CTS so awareness should be raised and interventions should specifically target this risk group.


Subject(s)
Carpal Tunnel Syndrome/epidemiology , Median Neuropathy/epidemiology , Occupational Diseases/epidemiology , Occupational Exposure/adverse effects , Adolescent , Adult , Aged , Carpal Tunnel Syndrome/etiology , Cross-Sectional Studies , Female , Humans , Logistic Models , Male , Median Neuropathy/etiology , Middle Aged , Missouri/epidemiology , Motor Activity , Occupational Diseases/etiology , Occupations , Prevalence , Risk Factors , Sex Distribution , Surveys and Questionnaires
14.
Eur J Radiol ; 68(3): 499-502, 2008 Dec.
Article in English | MEDLINE | ID: mdl-19189431

ABSTRACT

PURPOSE: Parkinson's disease (PD) is a chronic progressive disorder which is characterized by rest tremor, akinesia or bradykinesia and rigidity. Carpal tunnel syndrome (CTS) is caused by compression of median nerve and can occur as a result of repetitive trauma. The aim of this study was to estimate the prevalence of CTS in PD and evaluate the median nerve sonographically. MATERIALS AND METHODS: Fifty-three wrist of 29 patients with PD were included in the study according to Hoehn and Yahr (H&Y) clinical stage and divided into two groups. The first group consisted of 29 wrists of patients with mild PD (H&Y stage I-II). The second group consisted of 24 wrists of patients with severe PD (H&Y stage III-IV). Thirty-six wrists of 20 age-matched patients were used as control group. Both of the patients with PD and control group underwent sonography and electromyography (EMG). Axial sonograms of the median nerve were obtained at the level of distal radioulnar joint (level 1) and at the level of pisiform bone in the carpal tunnel (level 2). At each level, the cross-sectional area of the median nerve and flattening ratio were calculated. RESULTS: There was no significant difference for all parameters, except one parameter, between the patients with PD and control group, and also among mild and severe groups of PD and control group (p > 0.05). Interestingly, amplitude of median nerve in the second finger was significantly lower in PD patients than control group within normal limits (p=0.010). Of all wrists of PD patients, 13 (24.4%) have been diagnosed as CTS and 7 (19.4%) control wrists had CTS. Median nerve cross-sectional area of CTS patients were more than 10 mm2 in 6 (46%) wrists of PD patients but in only 1 (14%) control wrist at each level. Although it was not statistically significant, there was higher cross-sectional area at each level in patients with severe PD (level 1: 10.43+/-2.30 mm2, level 2: 10.35+/-3.19 mm2) than patients with mild PD (level 1: 9.93+/-2.61 mm2, level 2: 9.51+/-2.83 mm2) and control group (level 1: 9.69+/-3.19 mm2, level 2: 9.07+/-3.61 mm2). CONCLUSION: PD may pose a risk for the development of CTS due to the repetitive movement of tremor. Although sonography is not an ideal method of diagnosis for CTS, it may take our attention for indicating CTS in patients with PD especially in severe ones.


Subject(s)
Carpal Tunnel Syndrome/diagnostic imaging , Carpal Tunnel Syndrome/epidemiology , Median Neuropathy/diagnostic imaging , Median Neuropathy/epidemiology , Parkinson Disease/diagnostic imaging , Parkinson Disease/epidemiology , Risk Assessment/methods , Adult , Aged , Comorbidity , Female , Humans , Male , Middle Aged , Prevalence , Risk Factors , Turkey/epidemiology , Ultrasonography
16.
Eur J Radiol ; 67(3): 546-50, 2008 Sep.
Article in English | MEDLINE | ID: mdl-17855036

ABSTRACT

PURPOSE: Parkinson's disease (PD) is a chronic progressive disorder which is characterized by rest tremor, akinesia or bradykinesia and rigidity. Carpal tunnel syndrome (CTS) is caused by compression of median nerve and can occur as a result of repetitive trauma. The aim of this study was to estimate the prevalence of CTS in PD and evaluate the median nerve sonographically. MATERIALS AND METHODS: Fifty-three wrist of 29 patients with PD were included in the study according to Hoehn and Yahr (H&Y) clinical stage and divided into two groups. The first group consisted of 29 wrists of patients with mild PD (H&Y stage I-II). The second group consisted of 24 wrists of patients with severe PD (H&Y stage III-IV). Thirty-six wrists of 20 age-matched patients were used as control group. Both of the patients with PD and control group underwent sonography and electromyography (EMG). Axial sonograms of the median nerve were obtained at the level of distal radioulnar joint (level 1) and at the level of pisiform bone in the carpal tunnel (level 2). At each level, the cross-sectional area of the median nerve and flattening ratio were calculated. RESULTS: There was no significant difference for all parameters, except one parameter, between the patients with PD and control group, and also among mild and severe groups of PD and control group (p>0.05). Interestingly, amplitude of median nerve in the second finger was significantly lower in PD patients than control group within normal limits (p=0.010). Of all wrists of PD patients, 13 (24.4%) have been diagnosed as CTS and 7 (19.4%) control wrists had CTS. Median nerve cross-sectional area of CTS patients were more than 10mm(2) in 6 (46%) wrists of PD patients but in only 1 (14%) control wrist at each level. Although it was not statistically significant, there was higher cross-sectional area at each level in patients with severe PD (level 1: 10.43+/-2.30 mm(2), level 2: 10.35+/-3.19 mm(2)) than patients with mild PD (level 1: 9.93+/-2.61 mm(2), level 2: 9.51+/-2.83 mm(2)) and control group (level 1: 9.69+/-3.19 mm(2), level 2: 9.07+/-3.61 mm(2)). CONCLUSION: PD may pose a risk for the development of CTS due to the repetitive movement of tremor. Although sonography is not an ideal method of diagnosis for CTS, it may take our attention for indicating CTS in patients with PD especially in severe ones.


Subject(s)
Carpal Tunnel Syndrome/diagnostic imaging , Carpal Tunnel Syndrome/epidemiology , Median Neuropathy/diagnostic imaging , Median Neuropathy/epidemiology , Risk Assessment/methods , Adult , Aged , Comorbidity , Female , Humans , Male , Middle Aged , Prevalence , Risk Factors , Turkey/epidemiology , Ultrasonography
17.
Acta Neurol Scand ; 116(2): 113-7, 2007 Aug.
Article in English | MEDLINE | ID: mdl-17661797

ABSTRACT

Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy. Many factors such as diabetes mellitus, hypothyroidism, hormonal replacement therapy, corticosteroid use, rheumatoid arthritis and wrist fractures may cause CTS. Metabolic syndrome includes abdominal obesity, dyslipidemia, hyperglycemia, and hypertension that may cause CTS. In this study, we aimed to evaluate the relation between CTS and metabolic syndrome. We studied 107 (96 female and 11 male) right-handed patients who had a clinical and electrophysiologically confirmed diagnosis of CTS. We then divided the patients into two groups (patients with and without metabolic syndrome) according to the criteria of ATP III definition. Eighty (75%) of the patients with CTS had metabolic syndrome. Among the 80 patients with metabolic syndrome, CTS was found in 150 hands (43 mild, 58 moderate and 49 severe cases). Among the 27 patients without metabolic syndrome, CTS was found in 43 hands (27 mild, 14 moderate and 2 severe cases). The electrophysiological parameters (median nerve distal motor latency, median nerve motor amplitude, median nerve motor conduction velocity, median nerve sensory onset latency, median nerve sensory amplitude and median nerve sensory conduction velocity) were worse in patients with metabolic syndrome (P < 0.05). In conclusion, metabolic syndrome was found to be three times more common in patients with CTS and CTS was more severe in patients with metabolic syndrome when compared with those without metabolic syndrome.


Subject(s)
Carpal Tunnel Syndrome/epidemiology , Carpal Tunnel Syndrome/physiopathology , Metabolic Syndrome/epidemiology , Metabolic Syndrome/physiopathology , Adult , Aged , Carpal Tunnel Syndrome/diagnosis , Comorbidity , Dyslipidemias/diagnosis , Dyslipidemias/epidemiology , Dyslipidemias/physiopathology , Electrodiagnosis/methods , Female , Humans , Hyperglycemia/diagnosis , Hyperglycemia/epidemiology , Hyperglycemia/physiopathology , Male , Median Nerve/physiopathology , Median Neuropathy/diagnosis , Median Neuropathy/epidemiology , Median Neuropathy/physiopathology , Metabolic Syndrome/diagnosis , Middle Aged , Neural Conduction/physiology , Obesity/diagnosis , Obesity/epidemiology , Obesity/physiopathology , Risk Factors
18.
J Agric Saf Health ; 10(4): 247-56, 2004 Nov.
Article in English | MEDLINE | ID: mdl-15603224

ABSTRACT

Pronator syndrome (median nerve entrapment at the elbow) is a rare condition, but it is more common among women than men. A long-term retrospective follow-up study evaluating the outcome of surgical release of the median nerve for female machine milkers has never been carried out before, nor has a long-term study of non-treated female milkers with pronator syndrome. In the present study, two groups of machine milkers (surgical and non-surgical) were compared. The clinical examination focused on two parameters: focal tenderness and individual muscle strength. The results showed that the surgical group had no focal tenderness on palpation over the median nerve at the elbow and no selective weakness in the muscles examined, as compared to what was found before surgery. In the non-surgical group, focal tenderness was found in 12 out of 14, and 10 out of 14 showed the same weakness as in an earlier examination. While this study has limitations in sample size, surgical release of the median nerve at the elbow level, in cases of pronator syndrome, appears to provide an immediate as well as long-term return to normal strength of FPL and FDP II, along with a significant improvement in subjective status. In the non-surgical group, spontaneous improvement of the strength of FPL and FDP II was found in only four out of the 14 cases.


Subject(s)
Agricultural Workers' Diseases/epidemiology , Dairying/instrumentation , Median Neuropathy/epidemiology , Nerve Compression Syndromes/epidemiology , Adult , Aged , Agricultural Workers' Diseases/etiology , Agricultural Workers' Diseases/prevention & control , Female , Forearm/innervation , Humans , Longitudinal Studies , Median Nerve , Median Neuropathy/etiology , Median Neuropathy/prevention & control , Middle Aged , Nerve Compression Syndromes/etiology , Nerve Compression Syndromes/prevention & control , Neurologic Examination , Pronation , Retrospective Studies , Surveys and Questionnaires , Sweden/epidemiology
19.
Eur J Epidemiol ; 18(10): 983-93, 2003.
Article in English | MEDLINE | ID: mdl-14598929

ABSTRACT

OBJECTIVE: To ascertain whether carpal tunnel syndrome (CTS) in patients affected with toxic oil syndrome (TOS) is associated with conditions and diseases considered risk factors for CTS in the general population and/or with certain clinical manifestations of TOS. METHODS: We conducted a case-control study to compare 89 TOS patients residing in Madrid diagnosed with CTS from 1981 through July 2001 (cases) against 638 TOS patients not affected with CTS (controls). Risk factors for CTS and clinical manifestations of TOS were analyzed. RESULTS: Multivariate logistic regression analysis yielded the following odds ratios (95% confidence interval): 3.32 (1.47-7.50) for TOS-related neuropathy; 2.85 (1.14-7.13) for TOS-related thromboembolic events; 2.63 (1.36-5.06) for female gender; 0.43 (0.24-0.80) for TOS-related scleroderma; 0.26 (0.12 0.59) for smoking; and, in women, 2.53 (1.06-5.70) for fibrositis and 1.84 (1.04-3.20) for miscarriages. CONCLUSION: Our study findings support the hypothesis that CTS in TOS patients is more linked to certain clinical manifestations of TOS, mainly neuropathy, than to conditions and diseases considered risk factors for CTS in the general population.


Subject(s)
Carpal Tunnel Syndrome/epidemiology , Food Contamination , Plant Oils/poisoning , Carpal Tunnel Syndrome/chemically induced , Case-Control Studies , Fatty Acids, Monounsaturated , Female , Humans , Male , Median Neuropathy/chemically induced , Median Neuropathy/epidemiology , Odds Ratio , Poisoning/epidemiology , Poisoning/physiopathology , Rapeseed Oil , Risk Factors , Spain/epidemiology
20.
Am J Sports Med ; 31(4): 585-9, 2003.
Article in English | MEDLINE | ID: mdl-12860549

ABSTRACT

BACKGROUND: Although case reports have identified the presence of distal ulnar nerve sensory and motor dysfunction in long-distance cyclists, the actual incidence of this condition, referred to as "cyclist's palsy," is unknown. PURPOSE: To determine the incidence of distal ulnar nerve compression in cyclists. STUDY DESIGN: Prospective study. METHODS: Twenty-five road or mountain bike riders responded to a questionnaire and were then physically examined and interviewed before and after a 600-km bicycle ride. RESULTS: Twenty-three of the 25 cyclists experienced either motor or sensory symptoms, or both. Motor symptoms alone occurred in 36% of the hands (11 cyclists) tested; no significant difference in the incidence of motor symptoms was found among cyclists of various experience levels or based on handlebar types (mountain bike versus road bike). Sensory symptoms alone occurred in 10% of hands (four cyclists) tested, with the majority of these being in the ulnar distribution. A significantly higher proportion of mountain bike riders had sensory deficits compared with road bike riders; however, there was no significant difference in the occurrence of sensory deficits based on level of experience. A total of 24% of the hands (eight cyclists) tested experienced a combination of motor and sensory symptoms. These motor and sensory symptoms were equally distributed between road bike riders and mountain bike riders and riders of various experience levels. CONCLUSIONS: Cyclist's palsy occurs at high rates in both experienced and inexperienced cylists. Steps may be taken to decrease the incidence of cyclist's palsy; these include wearing cycling gloves, ensuring proper bicycle fit, and frequently changing hand position.


Subject(s)
Athletic Injuries/epidemiology , Bicycling/injuries , Median Neuropathy/epidemiology , Ulnar Neuropathies/epidemiology , Adult , Bicycling/classification , Female , Humans , Incidence , Male , Middle Aged , Prospective Studies , United States/epidemiology
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