1.
Lancet
; 388(10057): 2232, 2016 Nov 05.
Article
in English
| MEDLINE
| ID: mdl-27831470
Subject(s)
Alzheimer Disease/history , Apolipoproteins E/history , Membrane Transport Proteins/history , Neurodegenerative Diseases/history , Neurology/history , Alzheimer Disease/diagnosis , Alzheimer Disease/drug therapy , Alzheimer Disease/genetics , Amyotrophic Lateral Sclerosis/genetics , Amyotrophic Lateral Sclerosis/history , Apolipoproteins E/genetics , Faculty, Medical/history , Genetic Markers/drug effects , Genetic Markers/genetics , History, 20th Century , History, 21st Century , Humans , Membrane Transport Proteins/genetics , Mitochondrial Precursor Protein Import Complex Proteins , Muscular Dystrophies/genetics , Muscular Dystrophies/history , Neurodegenerative Diseases/genetics , Parkinson Disease/genetics , Parkinson Disease/history , United States
2.
Annu Rev Biophys
; 44: 257-83, 2015.
Article
in English
| MEDLINE
| ID: mdl-26098515
ABSTRACT
The ancient and ubiquitous major facilitator superfamily (MFS) represents the largest secondary transporter family and plays a crucial role in a multitude of physiological processes. MFS proteins transport a broad spectrum of ions and solutes across membranes via facilitated diffusion, symport, or antiport. In recent years, remarkable advances in understanding the structural biology of the MFS transporters have been made. This article reviews the history, classification, and general features of the MFS proteins; summarizes recent structural progress with a focus on the sugar porter family transporters exemplified by GLUT1; and discusses the molecular mechanisms of substrate binding, alternating access, and cotransport coupling.
Subject(s)
Membrane Transport Proteins/chemistry , Animals , Bacteria/chemistry , Crystallography, X-Ray , History, 20th Century , History, 21st Century , Humans , Membrane Transport Proteins/genetics , Membrane Transport Proteins/history , Membrane Transport Proteins/metabolism
3.
J Immunol
; 180(5): 2723-4, 2008 Mar 01.
Article
in English
| MEDLINE
| ID: mdl-18292486
Subject(s)
ATP-Binding Cassette Transporters/history , Antigen Presentation/immunology , Membrane Transport Proteins/history , ATP Binding Cassette Transporter, Subfamily B, Member 2 , ATP Binding Cassette Transporter, Subfamily B, Member 3 , Animals , Antigen Presentation/genetics , History, 20th Century , Humans , T-Lymphocytes, Cytotoxic/immunology , T-Lymphocytes, Cytotoxic/metabolism , T-Lymphocytes, Cytotoxic/virology
4.
J Immunol
; 180(5): 2729-32, 2008 Mar 01.
Article
in English
| MEDLINE
| ID: mdl-18292488
Subject(s)
ATP-Binding Cassette Transporters/history , Drug Resistance, Multiple , Histocompatibility Antigens Class II/history , Membrane Transport Proteins/history , Multigene Family/immunology , ATP Binding Cassette Transporter, Subfamily B, Member 2 , Amino Acid Sequence , Animals , Base Sequence , Biological Transport , Cell Line, Transformed , History, 20th Century , Humans , Mice , Mice, Inbred BALB C , Molecular Sequence Data , Rats
5.
C R Biol
; 328(6): 514-20, 2005 Jun.
Article
in English, French
| MEDLINE
| ID: mdl-15999435
Subject(s)
Lac Operon , Acetyltransferases/genetics , Acetyltransferases/history , Escherichia coli/genetics , Escherichia coli Proteins/genetics , Escherichia coli Proteins/history , History, 20th Century , Membrane Transport Proteins/genetics , Membrane Transport Proteins/history , Translations , beta-Galactosidase/genetics , beta-Galactosidase/history
6.
Pflugers Arch
; 448(6): 557-60, 2004 Sep.
Article
in English
| MEDLINE
| ID: mdl-15316782
7.
Neurology
; 57(10 Suppl 3): S52-9, 2001 Nov.
Article
in English
| MEDLINE
| ID: mdl-11775602
