1.
Sci Rep
; 11(1): 3673, 2021 02 11.
Article
in English
| MEDLINE
| ID: mdl-33574462
ABSTRACT
The morbidity and mortality of cryptococcal meningoencephalitis (CM) in previously healthy, HIV-negative individuals is increasingly recognized. We administered a healthcare associated quality of life (QOL) survey to the largest longitudinally followed cohort of these patients in the United States. We identified moderate or severe self-reported impairment in at least one QOL domain in 61% of subjects at least one year following diagnosis. Self-reported cognitive impairment was noted in 52% and sleep disturbance was noted in 55%. This is the first comprehensive study of cross-sectional long-term QOL in previously healthy patients following cryptococcal infection.
Subject(s)
Cryptococcus neoformans/pathogenicity , HIV Infections/epidemiology , HIV/pathogenicity , Meningitis, Cryptococcal/epidemiology , Adult , Cohort Studies , Female , HIV Infections/complications , HIV Infections/virology , Health Status , Humans , Male , Meningitis, Cryptococcal/ethnology , Meningitis, Cryptococcal/microbiology , Meningitis, Cryptococcal/virology , Middle Aged , Quality of Life
2.
Med J Aust
; 165(7): 403, 406, 1996 Oct 07.
Article
in English
| MEDLINE
| ID: mdl-8890853